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Volumn 2, Issue 4, 2007, Pages

Identification of the endogenous key substrates of the human organic cation transporter OCT2 and their implication in function of dopaminergic neurons

Author keywords

[No Author keywords available]

Indexed keywords

CYCLO(HISTIDYLPROLINE); ORGANIC CATION TRANSPORTER 3; SALSOLINOL; TETRAZOLIUM; TYROSINE 3 MONOOXYGENASE; CYCLOPEPTIDE; DOPAMINE; HISTIDYL-PROLINE DIKETOPIPERAZINE; NEUROPROTECTIVE AGENT; ORGANIC CATION TRANSPORTER; PIPERAZINE DERIVATIVE; SLC22A2 PROTEIN, HUMAN;

EID: 34548030734     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0000385     Document Type: Article
Times cited : (53)

References (26)
  • 1
    • 55349142058 scopus 로고    scopus 로고
    • Lesch KP, Murphy DL (2004) Molecular genetics of transporters for norepinephrine, dopamine, and serotonin in behavioral traits and complex diseases. In: Bröer S, Wagner CA, eds (2004) Membrane Transporter Diseases. New York: Kluwer Academic/Plenum Publishers. pp 349-364.
    • Lesch KP, Murphy DL (2004) Molecular genetics of transporters for norepinephrine, dopamine, and serotonin in behavioral traits and complex diseases. In: Bröer S, Wagner CA, eds (2004) Membrane Transporter Diseases. New York: Kluwer Academic/Plenum Publishers. pp 349-364.
  • 2
    • 0345866860 scopus 로고    scopus 로고
    • Pharmacological and physiological functions of the polyspecific organic cation transporters: OCT1, 2, and 3 (SLC22A1-3)
    • Jonker JW, Schinkel AH (2004) Pharmacological and physiological functions of the polyspecific organic cation transporters: OCT1, 2, and 3 (SLC22A1-3). J Pharmacol Exp Ther 308: 2-9.
    • (2004) J Pharmacol Exp Ther , vol.308 , pp. 2-9
    • Jonker, J.W.1    Schinkel, A.H.2
  • 3
    • 3042569768 scopus 로고    scopus 로고
    • Polyspecific organic cation transporters: Their functions and interactions with drugs
    • Koepsell H (2004) Polyspecific organic cation transporters: their functions and interactions with drugs. Trends Pharmacol Sci 25: 375-381.
    • (2004) Trends Pharmacol Sci , vol.25 , pp. 375-381
    • Koepsell, H.1
  • 4
    • 0025348687 scopus 로고
    • Structure and expression of the mouse Oct2a and Oct2b, two differentially spliced products of the same gene
    • Hatzopoulos AK, Stoykova AS, Erselius JR, Goulding M, Neuman T, et al. (1990) Structure and expression of the mouse Oct2a and Oct2b, two differentially spliced products of the same gene. Development 109: 349-362.
    • (1990) Development , vol.109 , pp. 349-362
    • Hatzopoulos, A.K.1    Stoykova, A.S.2    Erselius, J.R.3    Goulding, M.4    Neuman, T.5
  • 5
    • 0031824347 scopus 로고    scopus 로고
    • Human neurons express the polyspecific cation transporter hOCT2, which translocates monoamine neurotransmitters, amantadine, and memantine
    • Busch AE, Karbach U, Miska D, Gorboulev V, Akhoundova A, et al. (1998) Human neurons express the polyspecific cation transporter hOCT2, which translocates monoamine neurotransmitters, amantadine, and memantine. Mol Pharmacol 54: 342-352.
    • (1998) Mol Pharmacol , vol.54 , pp. 342-352
    • Busch, A.E.1    Karbach, U.2    Miska, D.3    Gorboulev, V.4    Akhoundova, A.5
  • 6
    • 34249989197 scopus 로고    scopus 로고
    • Extraneuronal moricamine transporter and organic cation transporters 1 and 2: A review of transport efficiency
    • Schomig E, Lazar A, Grundemann D (2006) Extraneuronal moricamine transporter and organic cation transporters 1 and 2: A review of transport efficiency. Handb Exp Pharmacol: 151-180.
    • (2006) Handb Exp Pharmacol , pp. 151-180
    • Schomig, E.1    Lazar, A.2    Grundemann, D.3
  • 8
    • 0032553546 scopus 로고    scopus 로고
    • Transport of monoamine transmitters by the organic cation transporter type 2, OCT2
    • Grundemann D, Koster S, Kiefer N, Breidert T, Engelhardt M, et al. (1998) Transport of monoamine transmitters by the organic cation transporter type 2, OCT2. J Biol Chem 273: 30915-30920.
    • (1998) J Biol Chem , vol.273 , pp. 30915-30920
    • Grundemann, D.1    Koster, S.2    Kiefer, N.3    Breidert, T.4    Engelhardt, M.5
  • 9
    • 0031766707 scopus 로고    scopus 로고
    • Limited proteolysis and physiological regulation: An example from thyrotropin-releasing hormone metabolism
    • Prasad C (1998) Limited proteolysis and physiological regulation: an example from thyrotropin-releasing hormone metabolism. Thyroid 8: 969-975.
    • (1998) Thyroid , vol.8 , pp. 969-975
    • Prasad, C.1
  • 10
    • 0025021697 scopus 로고
    • Neuropeptide-dopamine interactions. V. Cyclo(His-Pro) regulation of striatal dopamine transporter complex
    • Ikegami H, Prasad C (1990) Neuropeptide-dopamine interactions. V. Cyclo(His-Pro) regulation of striatal dopamine transporter complex. Peptides 11: 145-148.
    • (1990) Peptides , vol.11 , pp. 145-148
    • Ikegami, H.1    Prasad, C.2
  • 11
    • 0036719906 scopus 로고    scopus 로고
    • Physiological role of salsolinol: Its hypophysiotrophic function in the regulation of pituitary prolactin secretion
    • Toth BE, Bodnar I, Homicsko KG, Fulop F, Fekete MI, et al. (2002) Physiological role of salsolinol: its hypophysiotrophic function in the regulation of pituitary prolactin secretion. Neurotoxicol Teratol 24: 655-666.
    • (2002) Neurotoxicol Teratol , vol.24 , pp. 655-666
    • Toth, B.E.1    Bodnar, I.2    Homicsko, K.G.3    Fulop, F.4    Fekete, M.I.5
  • 13
    • 18344395117 scopus 로고    scopus 로고
    • Selective dopaminergic neurotoxicity of isoquinoline derivatives related to Parkinson's disease: Studies using heterologous expression systems of the dopamine transporter
    • Storch A, Ott S, Hwang YI, Ortmann R, Hein A, et al. (2002) Selective dopaminergic neurotoxicity of isoquinoline derivatives related to Parkinson's disease: studies using heterologous expression systems of the dopamine transporter. Biochem Pharmacol 63: 909-920.
    • (2002) Biochem Pharmacol , vol.63 , pp. 909-920
    • Storch, A.1    Ott, S.2    Hwang, Y.I.3    Ortmann, R.4    Hein, A.5
  • 14
    • 0036717067 scopus 로고    scopus 로고
    • Dopamine-derived endogenous; N-methyl-(R)-salsolinol: Its role in Parkinson's disease
    • Naoi M, Maruyama W, Akao Y, Yi H (2002) Dopamine-derived endogenous; N-methyl-(R)-salsolinol: its role in Parkinson's disease. Neurotoxicol Teratol 24: 579-591.
    • (2002) Neurotoxicol Teratol , vol.24 , pp. 579-591
    • Naoi, M.1    Maruyama, W.2    Akao, Y.3    Yi, H.4
  • 15
    • 0042840641 scopus 로고    scopus 로고
    • Primary structure and functional expression of the apical organic cation transporter from kidney epithehal LLC-PK1 cells
    • Grundemann D, Babin-Ebell J, Martel F, Ording N, Schmidt A, et al. (1997) Primary structure and functional expression of the apical organic cation transporter from kidney epithehal LLC-PK1 cells. J Biol Chem 272: 10408-10413.
    • (1997) J Biol Chem , vol.272 , pp. 10408-10413
    • Grundemann, D.1    Babin-Ebell, J.2    Martel, F.3    Ording, N.4    Schmidt, A.5
  • 16
    • 0030764929 scopus 로고    scopus 로고
    • Increase in salsolinol level in the cerebrospinal fluid of parkinsonian patients is related to dementia: Advantage of a new high-performance liquid chromatography methodology
    • Antkiewicz-Michaluk L, Krygowska-Wajs A, Szczudlik A, Romanska. I, Vetulani J (1997) Increase in salsolinol level in the cerebrospinal fluid of parkinsonian patients is related to dementia: advantage of a new high-performance liquid chromatography methodology. Biol Psychiatry 42: 514-518.
    • (1997) Biol Psychiatry , vol.42 , pp. 514-518
    • Antkiewicz-Michaluk, L.1    Krygowska-Wajs, A.2    Szczudlik, A.3    Romanska, I.4    Vetulani, J.5
  • 17
    • 0030614651 scopus 로고    scopus 로고
    • N-melhyl-(R)salsolinol as a dopaminergic neurotoxin: From an animal model to an early market of Parkinson's disease
    • Naoi M, Maruyama W, Dostert P, Hashizume Y (1997) N-melhyl-(R)salsolinol as a dopaminergic neurotoxin: from an animal model to an early market of Parkinson's disease. J Neural Transm Suppl 50: 89-105.
    • (1997) J Neural Transm , Issue.SUPPL. 50 , pp. 89-105
    • Naoi, M.1    Maruyama, W.2    Dostert, P.3    Hashizume, Y.4
  • 19
    • 0036020986 scopus 로고    scopus 로고
    • Polymorphisms in a human kidney xenobiotic transporter, OCT2, exhibit altered function
    • Leabman MK, Huang CG, Kawamoto M, Johns SJ, Stryke D, et al. (2002) Polymorphisms in a human kidney xenobiotic transporter, OCT2, exhibit altered function. Pharmacogenetics 12: 395-405.
    • (2002) Pharmacogenetics , vol.12 , pp. 395-405
    • Leabman, M.K.1    Huang, C.G.2    Kawamoto, M.3    Johns, S.J.4    Stryke, D.5
  • 20
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium, thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium, thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 21
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl MW (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29: e45.
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1
  • 22
    • 0032790412 scopus 로고    scopus 로고
    • HEK-293 cells expressing the human dopamine transporter are susceptible to low concentrations of 1-methyl-4-phenylpyridine (MPP+) via impairment of energy metabolism
    • Storch A, Ludolph AC, Schwarz J (1999) HEK-293 cells expressing the human dopamine transporter are susceptible to low concentrations of 1-methyl-4-phenylpyridine (MPP+) via impairment of energy metabolism. Neurochem Int 35: 393-403.
    • (1999) Neurochem Int , vol.35 , pp. 393-403
    • Storch, A.1    Ludolph, A.C.2    Schwarz, J.3
  • 23
    • 12144255196 scopus 로고    scopus 로고
    • Excitotoxic and post-ischemic neurodegeneration: Involvement of transglutaminases
    • Caccamo D, Campisi A, Curro M, Li Volti G, Vanella A, et al. (2004) Excitotoxic and post-ischemic neurodegeneration: Involvement of transglutaminases. Amino Acids 27: 373-379.
    • (2004) Amino Acids , vol.27 , pp. 373-379
    • Caccamo, D.1    Campisi, A.2    Curro, M.3    Li Volti, G.4    Vanella, A.5
  • 24
    • 0342785865 scopus 로고
    • Über 2,5-Diketopiperazine, II. Die Umsetzung des 2,5-Diketopiperazins mit Aldehyden und Nitrosoverbindungen.
    • Augustin M (1966) Über 2,5-Diketopiperazine, II. Die Umsetzung des 2,5-Diketopiperazins mit Aldehyden und Nitrosoverbindungen. J Prakt Chem 32: 158-166.
    • (1966) J Prakt Chem , vol.32 , pp. 158-166
    • Augustin, M.1
  • 25
    • 0036022593 scopus 로고    scopus 로고
    • Expression and pharmacological profile of the human organic cation transporters hOCT1 hOCT2 and hOCT3
    • Hayer-Zillgen M, Bruss M, Bonisch H (2002) Expression and pharmacological profile of the human organic cation transporters hOCT1 hOCT2 and hOCT3. Br J Pharmacol 136: 829-836.
    • (2002) Br J Pharmacol , vol.136 , pp. 829-836
    • Hayer-Zillgen, M.1    Bruss, M.2    Bonisch, H.3
  • 26
    • 0025954066 scopus 로고
    • Ageing and Parkinson's disease: Substantia. nigra regional selectivity
    • Fearnley JM, Lees AJ (1991) Ageing and Parkinson's disease: substantia. nigra regional selectivity. Brain 114(Pt 5): 2283-2301.
    • (1991) Brain , vol.114 , Issue.PART 5 , pp. 2283-2301
    • Fearnley, J.M.1    Lees, A.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.