-
1
-
-
0019957222
-
Platelet-derived growth factor. I. High yield purification and evidence for multiple forms
-
7068680
-
Raines EW, Ross R. Platelet-derived growth factor. I. High yield purification and evidence for multiple forms. J Biol Chem 1982, 257(9):5154-5160. 7068680.
-
(1982)
J Biol Chem
, vol.257
, Issue.9
, pp. 5154-5160
-
-
Raines, E.W.1
Ross, R.2
-
2
-
-
0018319599
-
Platelet-derived growth factor: purification and partial characterization
-
291037
-
Heldin CH, Westermark B, Wasteson A. Platelet-derived growth factor: purification and partial characterization. Proc Natl Acad Sci U S A 1979, 76(8):3722-3726. 10.1073/pnas.76.8.3722, 291037.
-
(1979)
Proc Natl Acad Sci U S A
, vol.76
, Issue.8
, pp. 3722-3726
-
-
Heldin, C.H.1
Westermark, B.2
Wasteson, A.3
-
3
-
-
0019820367
-
Human platelet-derived growth factor. Purification and resolution into two active protein fractions
-
7263691
-
Deuel TF, Huang JS, Proffitt RT, Baenziger JU, Chang D, Kennedy BB. Human platelet-derived growth factor. Purification and resolution into two active protein fractions. J Biol Chem 1981, 256(17):8896-8899. 7263691.
-
(1981)
J Biol Chem
, vol.256
, Issue.17
, pp. 8896-8899
-
-
Deuel, T.F.1
Huang, J.S.2
Proffitt, R.T.3
Baenziger, J.U.4
Chang, D.5
Kennedy, B.B.6
-
4
-
-
0018770444
-
Purification of human platelet-derived growth factor
-
287022
-
Antoniades HN, Scher CD, Stiles CD. Purification of human platelet-derived growth factor. Proc Natl Acad Sci U S A 1979, 76(4):1809-1813. 10.1073/pnas.76.4.1809, 287022.
-
(1979)
Proc Natl Acad Sci U S A
, vol.76
, Issue.4
, pp. 1809-1813
-
-
Antoniades, H.N.1
Scher, C.D.2
Stiles, C.D.3
-
5
-
-
84859890474
-
Autocrine PDGF stimulation in malignancies
-
22512244
-
Heldin CH. Autocrine PDGF stimulation in malignancies. Ups J Med Sci 2012, 117(2):83-91. 10.3109/03009734.2012.658119, 22512244.
-
(2012)
Ups J Med Sci
, vol.117
, Issue.2
, pp. 83-91
-
-
Heldin, C.H.1
-
6
-
-
0141799739
-
Gleevec (STI-571) inhibits lung cancer cell growth (A549) and potentiates the cisplatin effect in vitro
-
Zhang P, Gao WY, Turner S, Ducatman BS: Gleevec (STI-571) inhibits lung cancer cell growth (A549) and potentiates the cisplatin effect in vitro.Mol Cancer 2003, 2:1..
-
(2003)
Mol Cancer
, vol.2
, pp. 1
-
-
Zhang, P.1
Gao, W.Y.2
Turner, S.3
Ducatman, B.S.4
-
7
-
-
12144261476
-
Oncogenic derivatives of platelet-derived growth factor receptors
-
15583853
-
Jones AV, Cross NC. Oncogenic derivatives of platelet-derived growth factor receptors. Cell Mol Life Sci 2004, 61(23):2912-2923. 10.1007/s00018-004-4272-z, 15583853.
-
(2004)
Cell Mol Life Sci
, vol.61
, Issue.23
, pp. 2912-2923
-
-
Jones, A.V.1
Cross, N.C.2
-
8
-
-
0034053156
-
Radioimmunoassay for the measurement of thrombospondin in plasma and breast cyst fluid: validation and clinical application
-
10817245
-
Hayden K, Tetlow L, Byrne G, Bundred N. Radioimmunoassay for the measurement of thrombospondin in plasma and breast cyst fluid: validation and clinical application. Ann Clin Biochem 2000, 37(Pt 3):319-325. 10817245.
-
(2000)
Ann Clin Biochem
, vol.37
, pp. 319-325
-
-
Hayden, K.1
Tetlow, L.2
Byrne, G.3
Bundred, N.4
-
9
-
-
85027925291
-
PDGF: the nuts and bolts of signalling toolbox
-
21769672
-
Farooqi AA, Waseem S, Riaz AM, Dilawar BA, Mukhtar S, Minhaj S, Waseem MS, Daniel S, Malik BA, Nawaz A, Bhatti S. PDGF: the nuts and bolts of signalling toolbox. Tumour Biol 2011, 32(6):1057-1070. 10.1007/s13277-011-0212-3, 21769672.
-
(2011)
Tumour Biol
, vol.32
, Issue.6
, pp. 1057-1070
-
-
Farooqi, A.A.1
Waseem, S.2
Riaz, A.M.3
Dilawar, B.A.4
Mukhtar, S.5
Minhaj, S.6
Waseem, M.S.7
Daniel, S.8
Malik, B.A.9
Nawaz, A.10
Bhatti, S.11
-
10
-
-
0027488086
-
Tissue platelet derived-growth factor (PDGF) predicts for shortened survival and treatment failure in advanced breast cancer
-
8251649
-
Seymour L, Dajee D, Bezwoda WR. Tissue platelet derived-growth factor (PDGF) predicts for shortened survival and treatment failure in advanced breast cancer. Breast Cancer Res Treat 1993, 26(3):247-252. 10.1007/BF00665802, 8251649.
-
(1993)
Breast Cancer Res Treat
, vol.26
, Issue.3
, pp. 247-252
-
-
Seymour, L.1
Dajee, D.2
Bezwoda, W.R.3
-
11
-
-
0030725954
-
Expression in lung carcinomas of platelet-derived growth factor and its receptors
-
9389786
-
Kawai T, Hiroi S, Torikata C. Expression in lung carcinomas of platelet-derived growth factor and its receptors. Lab Invest 1997, 77(5):431-436. 9389786.
-
(1997)
Lab Invest
, vol.77
, Issue.5
, pp. 431-436
-
-
Kawai, T.1
Hiroi, S.2
Torikata, C.3
-
12
-
-
84861112214
-
Preclinical and clinical studies of estrogen deprivation support the PDGF/Abl pathway as a novel therapeutic target for overcoming endocrine resistance in breast cancer
-
Weigel MT, Ghazoui Z, Dunbier A, Pancholi S, Dowsett M, Martin LA: Preclinical and clinical studies of estrogen deprivation support the PDGF/Abl pathway as a novel therapeutic target for overcoming endocrine resistance in breast cancer.Breast Cancer Res 2012, 14(3):R78..
-
(2012)
Breast Cancer Res
, vol.14
, Issue.3
, pp. R78
-
-
Weigel, M.T.1
Ghazoui, Z.2
Dunbier, A.3
Pancholi, S.4
Dowsett, M.5
Martin, L.A.6
-
13
-
-
84871568254
-
Enhanced expression of the PDGFR/Abl signaling pathway in aromatase inhibitor-resistant breast cancer
-
22865780
-
Weigel MT, Banerjee S, Arnedos M, Salter J, A'Hern R, Dowsett M, Martin LA. Enhanced expression of the PDGFR/Abl signaling pathway in aromatase inhibitor-resistant breast cancer. Ann Oncol 2013, 24(1):126-133. 10.1093/annonc/mds240, 22865780.
-
(2013)
Ann Oncol
, vol.24
, Issue.1
, pp. 126-133
-
-
Weigel, M.T.1
Banerjee, S.2
Arnedos, M.3
Salter, J.4
A'Hern, R.5
Dowsett, M.6
Martin, L.A.7
-
14
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
19945376
-
Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelial-mesenchymal transitions in development and disease. Cell 2009, 139(5):871-890. 10.1016/j.cell.2009.11.007, 19945376.
-
(2009)
Cell
, vol.139
, Issue.5
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
15
-
-
84856015098
-
Epithelial-mesenchymal transition, cancer stem cells and treatment resistance
-
Dave B, Mittal V, Tan NM, Chang JC: Epithelial-mesenchymal transition, cancer stem cells and treatment resistance.Breast Cancer Res 2012, 14(1):202..
-
(2012)
Breast Cancer Res
, vol.14
, Issue.1
, pp. 202
-
-
Dave, B.1
Mittal, V.2
Tan, N.M.3
Chang, J.C.4
-
16
-
-
84861676291
-
Epithelial-mesenchymal transition and breast cancer: role, molecular mechanisms and clinical impact
-
22118888
-
Foroni C, Broggini M, Generali D, Damia G. Epithelial-mesenchymal transition and breast cancer: role, molecular mechanisms and clinical impact. Cancer Treat Rev 2012, 38(6):689-697. 10.1016/j.ctrv.2011.11.001, 22118888.
-
(2012)
Cancer Treat Rev
, vol.38
, Issue.6
, pp. 689-697
-
-
Foroni, C.1
Broggini, M.2
Generali, D.3
Damia, G.4
-
17
-
-
80755173296
-
Breast cancer epithelial-to-mesenchymal transition: examining the functional consequences of plasticity
-
Drasin DJ, Robin TP, Ford HL: Breast cancer epithelial-to-mesenchymal transition: examining the functional consequences of plasticity.Breast Cancer Res 2011, 13(6):226..
-
(2011)
Breast Cancer Res
, vol.13
, Issue.6
, pp. 226
-
-
Drasin, D.J.1
Robin, T.P.2
Ford, H.L.3
-
18
-
-
0037468875
-
Discovery of 5-[5-fluoro-2-oxo-1,2- dihydroindol-(3Z)-ylidenemethyl]-2,4- dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide, a novel tyrosine kinase inhibitor targeting vascular endothelial and platelet-derived growth factor receptor tyrosine kinase
-
12646019
-
Sun L, Liang C, Shirazian S, Zhou Y, Miller T, Cui J, Fukuda JY, Chu JY, Nematalla A, Wang X, Chen H, Sistla A, Luu TC, Tang F, Wei J, Tang C. Discovery of 5-[5-fluoro-2-oxo-1,2- dihydroindol-(3Z)-ylidenemethyl]-2,4- dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide, a novel tyrosine kinase inhibitor targeting vascular endothelial and platelet-derived growth factor receptor tyrosine kinase. J Med Chem 2003, 46(7):1116-1119. 10.1021/jm0204183, 12646019.
-
(2003)
J Med Chem
, vol.46
, Issue.7
, pp. 1116-1119
-
-
Sun, L.1
Liang, C.2
Shirazian, S.3
Zhou, Y.4
Miller, T.5
Cui, J.6
Fukuda, J.Y.7
Chu, J.Y.8
Nematalla, A.9
Wang, X.10
Chen, H.11
Sistla, A.12
Luu, T.C.13
Tang, F.14
Wei, J.15
Tang, C.16
-
19
-
-
0038204144
-
SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo
-
12531805
-
O'Farrell AM, Abrams TJ, Yuen HA, Ngai TJ, Louie SG, Yee KW, Wong LM, Hong W, Lee LB, Town A, Smolich BD, Manning WC, Murray LJ, Heinrich MC, Cherrington JM. SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo. Blood 2003, 101(9):3597-3605. 10.1182/blood-2002-07-2307, 12531805.
-
(2003)
Blood
, vol.101
, Issue.9
, pp. 3597-3605
-
-
O'Farrell, A.M.1
Abrams, T.J.2
Yuen, H.A.3
Ngai, T.J.4
Louie, S.G.5
Yee, K.W.6
Wong, L.M.7
Hong, W.8
Lee, L.B.9
Town, A.10
Smolich, B.D.11
Manning, W.C.12
Murray, L.J.13
Heinrich, M.C.14
Cherrington, J.M.15
-
20
-
-
12244301581
-
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship
-
12538485
-
Mendel DB, Laird AD, Xin X, Louie SG, Christensen JG, Li G, Schreck RE, Abrams TJ, Ngai TJ, Lee LB, Murray LJ, Carver J, Chan E, Moss KG, Haznedar JO, Sukbuntherng J, Blake RA, Sun L, Tang C, Miller T, Shirazian S, McMahon G, Cherrington JM. In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship. Clin Cancer Res 2003, 9(1):327-337. 12538485.
-
(2003)
Clin Cancer Res
, vol.9
, Issue.1
, pp. 327-337
-
-
Mendel, D.B.1
Laird, A.D.2
Xin, X.3
Louie, S.G.4
Christensen, J.G.5
Li, G.6
Schreck, R.E.7
Abrams, T.J.8
Ngai, T.J.9
Lee, L.B.10
Murray, L.J.11
Carver, J.12
Chan, E.13
Moss, K.G.14
Haznedar, J.O.15
Sukbuntherng, J.16
Blake, R.A.17
Sun, L.18
Tang, C.19
Miller, T.20
Shirazian, S.21
McMahon, G.22
Cherrington, J.M.23
more..
-
21
-
-
79954499886
-
Regorafenib (BAY 73-4506): a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity
-
21170960
-
Wilhelm SM, Dumas J, Adnane L, Lynch M, Carter CA, Schutz G, Thierauch KH, Zopf D. Regorafenib (BAY 73-4506): a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity. Int J Cancer 2011, 129(1):245-255. 10.1002/ijc.25864, 21170960.
-
(2011)
Int J Cancer
, vol.129
, Issue.1
, pp. 245-255
-
-
Wilhelm, S.M.1
Dumas, J.2
Adnane, L.3
Lynch, M.4
Carter, C.A.5
Schutz, G.6
Thierauch, K.H.7
Zopf, D.8
-
22
-
-
77953441261
-
Targeted therapy for metastatic renal cell carcinoma: current treatment and future directions
-
21789125
-
Heng DY, Kollmannsberger C, Chi KN. Targeted therapy for metastatic renal cell carcinoma: current treatment and future directions. Ther Adv Med Oncol 2010, 2(1):39-49. 10.1177/1758834009352498, 21789125.
-
(2010)
Ther Adv Med Oncol
, vol.2
, Issue.1
, pp. 39-49
-
-
Heng, D.Y.1
Kollmannsberger, C.2
Chi, K.N.3
-
23
-
-
70349658639
-
Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT
-
Dubreuil P, Letard S, Ciufolini M, Gros L, Humbert M, Casteran N, Borge L, Hajem B, Lermet A, Sippl W, Voisset E, Arock M, Auclair C, Leventhal PS, Mansfield CD, Moussy A, Hermine O: Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT.PLoS One 2009, 4(9):e7258..
-
(2009)
PLoS One
, vol.4
, Issue.9
, pp. e7258
-
-
Dubreuil, P.1
Letard, S.2
Ciufolini, M.3
Gros, L.4
Humbert, M.5
Casteran, N.6
Borge, L.7
Hajem, B.8
Lermet, A.9
Sippl, W.10
Voisset, E.11
Arock, M.12
Auclair, C.13
Leventhal, P.S.14
Mansfield, C.D.15
Moussy, A.16
Hermine, O.17
-
24
-
-
57149112342
-
Masitinib is safe and effective for the treatment of canine mast cell tumors
-
18823406
-
Hahn KA, Ogilvie G, Rusk T, Devauchelle P, Leblanc A, Legendre A, Powers B, Leventhal PS, Kinet JP, Palmerini F, Dubreuil P, Moussy A, Hermine O. Masitinib is safe and effective for the treatment of canine mast cell tumors. J Vet Intern Med 2008, 22(6):1301-1309. 10.1111/j.1939-1676.2008.0190.x, 18823406.
-
(2008)
J Vet Intern Med
, vol.22
, Issue.6
, pp. 1301-1309
-
-
Hahn, K.A.1
Ogilvie, G.2
Rusk, T.3
Devauchelle, P.4
Leblanc, A.5
Legendre, A.6
Powers, B.7
Leventhal, P.S.8
Kinet, J.P.9
Palmerini, F.10
Dubreuil, P.11
Moussy, A.12
Hermine, O.13
-
25
-
-
80655139160
-
Mammary tumors that become independent of the type I insulin-like growth factor receptor express elevated levels of platelet-derived growth factor receptors
-
Campbell CI, Moorehead RA: Mammary tumors that become independent of the type I insulin-like growth factor receptor express elevated levels of platelet-derived growth factor receptors.BMC Cancer 2011, 11:480..
-
(2011)
BMC Cance
, vol.11
, pp. 480
-
-
Campbell, C.I.1
Moorehead, R.A.2
-
26
-
-
80051650773
-
Murine mammary tumor cells with a claudin-low genotype
-
Campbell CI, Thompson DE, Siwicky MD, Moorehead RA: Murine mammary tumor cells with a claudin-low genotype.Cancer Cell Int 2011, 11:28..
-
(2011)
Cancer Cell Int
, vol.11
, pp. 28
-
-
Campbell, C.I.1
Thompson, D.E.2
Siwicky, M.D.3
Moorehead, R.A.4
-
27
-
-
84863722180
-
Transgenic IGF-IR overexpression induces mammary tumors with basal-like characteristics while IGF-IR independent mammary tumors express a claudin-low gene signature
-
22020329
-
Franks SE, Campbell CI, Barnett EF, Siwicky MD, Livingstone J, Cory S, Moorehead RA. Transgenic IGF-IR overexpression induces mammary tumors with basal-like characteristics while IGF-IR independent mammary tumors express a claudin-low gene signature. Oncogene 2012, 31(27):3298-3309. 10.1038/onc.2011.486, 22020329.
-
(2012)
Oncogene
, vol.31
, Issue.27
, pp. 3298-3309
-
-
Franks, S.E.1
Campbell, C.I.2
Barnett, E.F.3
Siwicky, M.D.4
Livingstone, J.5
Cory, S.6
Moorehead, R.A.7
-
28
-
-
78049308800
-
Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer
-
Prat A, Parker JS, Karginova O, Fan C, Livasy C, Herschkowitz JI, He X, Perou CM: Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer.Breast Cancer Res 2010, 12(5):R68..
-
(2010)
Breast Cancer Res
, vol.12
, Issue.5
, pp. R68
-
-
Prat, A.1
Parker, J.S.2
Karginova, O.3
Fan, C.4
Livasy, C.5
Herschkowitz, J.I.6
He, X.7
Perou, C.M.8
-
29
-
-
66249109653
-
Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics
-
19435916
-
Hennessy BT, Gonzalez-Angulo AM, Stemke-Hale K, Gilcrease MZ, Krishnamurthy S, Lee JS, Fridlyand J, Sahin A, Agarwal R, Joy C, Liu W, Stivers D, Baggerly K, Carey M, Lluch A, Monteagudo C, He X, Weigman V, Fan C, Palazzo J, Hortobagyi GN, Nolden LK, Wang NJ, Valero V, Gray JW, Perou CM, Mills GB. Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics. Cancer Res 2009, 69(10):4116-4124. 10.1158/0008-5472.CAN-08-3441, 19435916.
-
(2009)
Cancer Res
, vol.69
, Issue.10
, pp. 4116-4124
-
-
Hennessy, B.T.1
Gonzalez-Angulo, A.M.2
Stemke-Hale, K.3
Gilcrease, M.Z.4
Krishnamurthy, S.5
Lee, J.S.6
Fridlyand, J.7
Sahin, A.8
Agarwal, R.9
Joy, C.10
Liu, W.11
Stivers, D.12
Baggerly, K.13
Carey, M.14
Lluch, A.15
Monteagudo, C.16
He, X.17
Weigman, V.18
Fan, C.19
Palazzo, J.20
Hortobagyi, G.N.21
Nolden, L.K.22
Wang, N.J.23
Valero, V.24
Gray, J.W.25
Perou, C.M.26
Mills, G.B.27
more..
-
30
-
-
51049089793
-
Characterization of a novel primary mammary tumor cell line reveals that cyclin D1 is regulated by the type I insulin-like growth factor receptor
-
18505926
-
Jones RA, Campbell CI, Petrik JJ, Moorehead RA. Characterization of a novel primary mammary tumor cell line reveals that cyclin D1 is regulated by the type I insulin-like growth factor receptor. Mol Cancer Res 2008, 6(5):819-828. 10.1158/1541-7786.MCR-07-2157, 18505926.
-
(2008)
Mol Cancer Res
, vol.6
, Issue.5
, pp. 819-828
-
-
Jones, R.A.1
Campbell, C.I.2
Petrik, J.J.3
Moorehead, R.A.4
-
31
-
-
77957572850
-
SU11248, a selective tyrosine kinases inhibitor suppresses breast tumor angiogenesis and growth via targeting both tumor vasculature and breast cancer cells
-
20686367
-
Young E, Miele L, Tucker KB, Huang M, Wells J, Gu JW. SU11248, a selective tyrosine kinases inhibitor suppresses breast tumor angiogenesis and growth via targeting both tumor vasculature and breast cancer cells. Cancer Biol Ther 2010, 10(7):703-711. 10.4161/cbt.10.7.12904, 20686367.
-
(2010)
Cancer Biol Ther
, vol.10
, Issue.7
, pp. 703-711
-
-
Young, E.1
Miele, L.2
Tucker, K.B.3
Huang, M.4
Wells, J.5
Gu, J.W.6
-
32
-
-
56349117935
-
Combination of imatinib and vinorelbine enhances cell growth inhibition in breast cancer cells via PDGFR beta signalling
-
18809244
-
Weigel MT, Meinhold-Heerlein I, Bauerschlag DO, Schem C, Bauer M, Jonat W, Maass N, Mundhenke C. Combination of imatinib and vinorelbine enhances cell growth inhibition in breast cancer cells via PDGFR beta signalling. Cancer Lett 2009, 273(1):70-79. 10.1016/j.canlet.2008.07.040, 18809244.
-
(2009)
Cancer Lett
, vol.273
, Issue.1
, pp. 70-79
-
-
Weigel, M.T.1
Meinhold-Heerlein, I.2
Bauerschlag, D.O.3
Schem, C.4
Bauer, M.5
Jonat, W.6
Maass, N.7
Mundhenke, C.8
-
33
-
-
84877709417
-
Imatinib as a key inhibitor of the platelet-derived growth factor receptor mediated expression of cell surface heparan sulfate proteoglycans and functional properties of breast cancer cells
-
23374223
-
Malavaki CJ, Roussidis AE, Gialeli C, Kletsas D, Tsegenidis T, Theocharis AD, Tzanakakis GN, Karamanos NK. Imatinib as a key inhibitor of the platelet-derived growth factor receptor mediated expression of cell surface heparan sulfate proteoglycans and functional properties of breast cancer cells. The FEBS journal 2013, 280(10):2477-2489. 10.1111/febs.12163, 23374223.
-
(2013)
The FEBS journal
, vol.280
, Issue.10
, pp. 2477-2489
-
-
Malavaki, C.J.1
Roussidis, A.E.2
Gialeli, C.3
Kletsas, D.4
Tsegenidis, T.5
Theocharis, A.D.6
Tzanakakis, G.N.7
Karamanos, N.K.8
-
34
-
-
77955295899
-
In vitro effects of imatinib mesylate on radiosensitivity and chemosensitivity of breast cancer cells
-
Weigel MT, Dahmke L, Schem C, Bauerschlag DO, Weber K, Niehoff P, Bauer M, Strauss A, Jonat W, Maass N, Mundhenke C: In vitro effects of imatinib mesylate on radiosensitivity and chemosensitivity of breast cancer cells.BMC Cancer 2010, 10:412..
-
(2010)
BMC Cancer
, vol.10
, pp. 412
-
-
Weigel, M.T.1
Dahmke, L.2
Schem, C.3
Bauerschlag, D.O.4
Weber, K.5
Niehoff, P.6
Bauer, M.7
Strauss, A.8
Jonat, W.9
Maass, N.10
Mundhenke, C.11
-
35
-
-
68149137164
-
Single- and multiple-dose disposition kinetics of sunitinib malate, a multitargeted receptor tyrosine kinase inhibitor: comparative plasma kinetics in non-clinical species
-
19169880
-
Haznedar JO, Patyna S, Bello CL, Peng GW, Speed W, Yu X, Zhang Q, Sukbuntherng J, Sweeny DJ, Antonian L, Wu EY. Single- and multiple-dose disposition kinetics of sunitinib malate, a multitargeted receptor tyrosine kinase inhibitor: comparative plasma kinetics in non-clinical species. Cancer Chemother Pharmacol 2009, 64(4):691-706. 10.1007/s00280-008-0917-1, 19169880.
-
(2009)
Cancer Chemother Pharmacol
, vol.64
, Issue.4
, pp. 691-706
-
-
Haznedar, J.O.1
Patyna, S.2
Bello, C.L.3
Peng, G.W.4
Speed, W.5
Yu, X.6
Zhang, Q.7
Sukbuntherng, J.8
Sweeny, D.J.9
Antonian, L.10
Wu, E.Y.11
-
36
-
-
37249072373
-
A phase I and pharmacokinetic study of sunitinib administered daily for 2 weeks, followed by a 1-week off period
-
17505827
-
Britten CD, Kabbinavar F, Hecht JR, Bello CL, Li J, Baum C, Slamon D. A phase I and pharmacokinetic study of sunitinib administered daily for 2 weeks, followed by a 1-week off period. Cancer Chemother Pharmacol 2008, 61(3):515-524. 10.1007/s00280-007-0498-4, 17505827.
-
(2008)
Cancer Chemother Pharmacol
, vol.61
, Issue.3
, pp. 515-524
-
-
Britten, C.D.1
Kabbinavar, F.2
Hecht, J.R.3
Bello, C.L.4
Li, J.5
Baum, C.6
Slamon, D.7
-
37
-
-
82555189379
-
Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance
-
21980135
-
Gotink KJ, Broxterman HJ, Labots M, de Haas RR, Dekker H, Honeywell RJ, Rudek MA, Beerepoot LV, Musters RJ, Jansen G, Griffioen AW, Assaraf YG, Pili R, Peters GJ, Verheul HM. Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance. Clin Cancer Res 2011, 17(23):7337-7346. 10.1158/1078-0432.CCR-11-1667, 21980135.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.23
, pp. 7337-7346
-
-
Gotink, K.J.1
Broxterman, H.J.2
Labots, M.3
de Haas, R.R.4
Dekker, H.5
Honeywell, R.J.6
Rudek, M.A.7
Beerepoot, L.V.8
Musters, R.J.9
Jansen, G.10
Griffioen, A.W.11
Assaraf, Y.G.12
Pili, R.13
Peters, G.J.14
Verheul, H.M.15
-
38
-
-
84899121465
-
Regorafenib in Japanese patients with solid tumors: phase I study of safety, efficacy, and pharmacokinetics
-
23553067
-
Sunakawa Y, Furuse J, Okusaka T, Ikeda M, Nagashima F, Ueno H, Mitsunaga S, Hashizume K, Ito Y, Sasaki Y. Regorafenib in Japanese patients with solid tumors: phase I study of safety, efficacy, and pharmacokinetics. Invest New Drugs 2014, 32(1):104-112. 10.1007/s10637-013-9953-8, 23553067.
-
(2014)
Invest New Drugs
, vol.32
, Issue.1
, pp. 104-112
-
-
Sunakawa, Y.1
Furuse, J.2
Okusaka, T.3
Ikeda, M.4
Nagashima, F.5
Ueno, H.6
Mitsunaga, S.7
Hashizume, K.8
Ito, Y.9
Sasaki, Y.10
-
39
-
-
84903814879
-
Population pharmacokinetics of imatinib in Iranian patients with chronic-phase chronic myeloid leukemia
-
24817601
-
Golabchifar AA, Rezaee S, Ghavamzadeh A, Alimoghaddam K, Dinan NM, Rouini MR. Population pharmacokinetics of imatinib in Iranian patients with chronic-phase chronic myeloid leukemia. Cancer Chemother Pharmacol 2014, 74(1):85-93. 10.1007/s00280-014-2473-1, 24817601.
-
(2014)
Cancer Chemother Pharmacol
, vol.74
, Issue.1
, pp. 85-93
-
-
Golabchifar, A.A.1
Rezaee, S.2
Ghavamzadeh, A.3
Alimoghaddam, K.4
Dinan, N.M.5
Rouini, M.R.6
-
40
-
-
70949104183
-
Pharmacokinetics of masitinib in cats
-
19533403
-
Bellamy F, Bader T, Moussy A, Hermine O. Pharmacokinetics of masitinib in cats. Vet Res Commun 2009, 33(8):831-837. 10.1007/s11259-009-9231-6, 19533403.
-
(2009)
Vet Res Commun
, vol.33
, Issue.8
, pp. 831-837
-
-
Bellamy, F.1
Bader, T.2
Moussy, A.3
Hermine, O.4
-
41
-
-
84884151634
-
Randomized phase II study of sunitinib versus standard of care for patients with previously treated advanced triple-negative breast cancer
-
23958375
-
Curigliano G, Pivot X, Cortes J, Elias A, Cesari R, Khosravan R, Collier M, Huang X, Cataruozolo PE, Kern KA, Goldhirsch A. Randomized phase II study of sunitinib versus standard of care for patients with previously treated advanced triple-negative breast cancer. Breast 2013, 22(5):650-656. 10.1016/j.breast.2013.07.037, 23958375.
-
(2013)
Breast
, vol.22
, Issue.5
, pp. 650-656
-
-
Curigliano, G.1
Pivot, X.2
Cortes, J.3
Elias, A.4
Cesari, R.5
Khosravan, R.6
Collier, M.7
Huang, X.8
Cataruozolo, P.E.9
Kern, K.A.10
Goldhirsch, A.11
-
42
-
-
84884126500
-
Phase III trial of sunitinib in combination with capecitabine versus capecitabine monotherapy for the treatment of patients with pretreated metastatic breast cancer
-
23857972
-
Crown JP, Dieras V, Staroslawska E, Yardley DA, Bachelot T, Davidson N, Wildiers H, Fasching PA, Capitain O, Ramos M, Greil R, Cognetti F, Fountzilas G, Blasinska-Morawiec M, Liedtke C, Kreienberg R, Miller WH, Tassell V, Huang X, Paolini J, Kern KA, Romieu G. Phase III trial of sunitinib in combination with capecitabine versus capecitabine monotherapy for the treatment of patients with pretreated metastatic breast cancer. J Clin Oncol 2013, 31(23):2870-2878. 10.1200/JCO.2012.43.3391, 23857972.
-
(2013)
J Clin Oncol
, vol.31
, Issue.23
, pp. 2870-2878
-
-
Crown, J.P.1
Dieras, V.2
Staroslawska, E.3
Yardley, D.A.4
Bachelot, T.5
Davidson, N.6
Wildiers, H.7
Fasching, P.A.8
Capitain, O.9
Ramos, M.10
Greil, R.11
Cognetti, F.12
Fountzilas, G.13
Blasinska-Morawiec, M.14
Liedtke, C.15
Kreienberg, R.16
Miller, W.H.17
Tassell, V.18
Huang, X.19
Paolini, J.20
Kern, K.A.21
Romieu, G.22
more..
-
43
-
-
84860625265
-
First-line treatment of advanced breast cancer with sunitinib in combination with docetaxel versus docetaxel alone: results of a prospective, randomized phase III study
-
22331954
-
Bergh J, Bondarenko IM, Lichinitser MR, Liljegren A, Greil R, Voytko NL, Makhson AN, Cortes J, Lortholary A, Bischoff J, Chan A, Delaloge S, Huang X, Kern KA, Giorgetti C. First-line treatment of advanced breast cancer with sunitinib in combination with docetaxel versus docetaxel alone: results of a prospective, randomized phase III study. J Clin Oncol 2012, 30(9):921-929. 10.1200/JCO.2011.35.7376, 22331954.
-
(2012)
J Clin Oncol
, vol.30
, Issue.9
, pp. 921-929
-
-
Bergh, J.1
Bondarenko, I.M.2
Lichinitser, M.R.3
Liljegren, A.4
Greil, R.5
Voytko, N.L.6
Makhson, A.N.7
Cortes, J.8
Lortholary, A.9
Bischoff, J.10
Chan, A.11
Delaloge, S.12
Huang, X.13
Kern, K.A.14
Giorgetti, C.15
-
44
-
-
84883621632
-
Protein kinase C alpha is a central signaling node and therapeutic target for breast cancer stem cells
-
24029232
-
Tam WL, Lu H, Buikhuisen J, Soh BS, Lim E, Reinhardt F, Wu ZJ, Krall JA, Bierie B, Guo W, Chen X, Liu XS, Brown M, Lim B, Weinberg RA. Protein kinase C alpha is a central signaling node and therapeutic target for breast cancer stem cells. Cancer Cell 2013, 24(3):347-364. 10.1016/j.ccr.2013.08.005, 24029232.
-
(2013)
Cancer Cell
, vol.24
, Issue.3
, pp. 347-364
-
-
Tam, W.L.1
Lu, H.2
Buikhuisen, J.3
Soh, B.S.4
Lim, E.5
Reinhardt, F.6
Wu, Z.J.7
Krall, J.A.8
Bierie, B.9
Guo, W.10
Chen, X.11
Liu, X.S.12
Brown, M.13
Lim, B.14
Weinberg, R.A.15
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