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Volumn 11, Issue , 2011, Pages

Mammary tumors that become independent of the type I insulin-like growth factor receptor express elevated levels of platelet-derived growth factor receptors

Author keywords

Breast cancer; Igf ir; Migration; Pdgfr; Resistance

Indexed keywords

PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; SOMATOMEDIN C RECEPTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR;

EID: 80655139160     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-11-480     Document Type: Article
Times cited : (18)

References (47)
  • 1
    • 33646712747 scopus 로고    scopus 로고
    • Mechanisms of Disease: understanding resistance to HER2-targeted therapy in human breast cancer
    • 10.1038/ncponc0509, 16683005
    • Nahta R, Yu D, Hung MC, Hortobagyi GN, Esteva FJ. Mechanisms of Disease: understanding resistance to HER2-targeted therapy in human breast cancer. Nat Clin Pract Oncol 2006, 3:269-280. 10.1038/ncponc0509, 16683005.
    • (2006) Nat Clin Pract Oncol , vol.3 , pp. 269-280
    • Nahta, R.1    Yu, D.2    Hung, M.C.3    Hortobagyi, G.N.4    Esteva, F.J.5
  • 2
    • 57149143868 scopus 로고    scopus 로고
    • Growth hormone and insulin-like growth factor-I in the transition from normal mammary development to preneoplastic mammary lesions
    • Kleinberg DL, Wood TL, Furth PA, Lee AV. Growth hormone and insulin-like growth factor-I in the transition from normal mammary development to preneoplastic mammary lesions. Endocr Rev 2009, 30:51-74.
    • (2009) Endocr Rev , vol.30 , pp. 51-74
    • Kleinberg, D.L.1    Wood, T.L.2    Furth, P.A.3    Lee, A.V.4
  • 3
    • 0024460381 scopus 로고
    • Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice
    • 10.1172/JCI114315, 304004, 2553774
    • Arteaga C, Kitten K, Coronado E. Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice. J Clin Invest 1989, 84:1418-1423. 10.1172/JCI114315, 304004, 2553774.
    • (1989) J Clin Invest , vol.84 , pp. 1418-1423
    • Arteaga, C.1    Kitten, K.2    Coronado, E.3
  • 4
    • 9144234724 scopus 로고    scopus 로고
    • A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo
    • Burtrum D, Zhu Z, Lu D, Anderson DM, Prewett M, Pereira DS, et al. A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo. Cancer Res 2003, 63:8912-8921.
    • (2003) Cancer Res , vol.63 , pp. 8912-8921
    • Burtrum, D.1    Zhu, Z.2    Lu, D.3    Anderson, D.M.4    Prewett, M.5    Pereira, D.S.6
  • 5
    • 0034115368 scopus 로고    scopus 로고
    • Treatment of human breast cancer cells with antisense RNA to the type I insulin-like growth factor receptor inhibits cell growth, suppresses tumorigenesis, alters the metastatic potential, and prolongs survival in vivo
    • 10.1038/sj.cgt.7700126, 10766344
    • Chernicky CL, Yi L, Tan H, Gan SU, Ilan J. Treatment of human breast cancer cells with antisense RNA to the type I insulin-like growth factor receptor inhibits cell growth, suppresses tumorigenesis, alters the metastatic potential, and prolongs survival in vivo. Cancer Gene Ther 2000, 7:384-395. 10.1038/sj.cgt.7700126, 10766344.
    • (2000) Cancer Gene Ther , vol.7 , pp. 384-395
    • Chernicky, C.L.1    Yi, L.2    Tan, H.3    Gan, S.U.4    Ilan, J.5
  • 6
    • 0036214015 scopus 로고    scopus 로고
    • Treatment of murine breast cancer cells with antisense RNA to the type I insulin-like growth factor receptor decreases the level of plasminogen activator transcripts, inhibits cell growth in vitro, and reduces tumorigenesis in vivo
    • 10.1136/mp.55.2.102, 1187158, 11950959
    • Chernicky CL, Tan H, Yi L, Loret D, Ilan J. Treatment of murine breast cancer cells with antisense RNA to the type I insulin-like growth factor receptor decreases the level of plasminogen activator transcripts, inhibits cell growth in vitro, and reduces tumorigenesis in vivo. Mol Pathol 2002, 55:102-109. 10.1136/mp.55.2.102, 1187158, 11950959.
    • (2002) Mol Pathol , vol.55 , pp. 102-109
    • Chernicky, C.L.1    Tan, H.2    Yi, L.3    Loret, D.4    Ilan, J.5
  • 7
    • 3142717695 scopus 로고    scopus 로고
    • Inhibition of in vivo breast cancer growth by antisense oligodeoxynucleotides to type I insulin-like growth factor receptor mRNA involves inactivation of ErbBs, PI-3 K/Akt and p42/p44 MAPK signaling pathways but not modulation of progesterone receptor activity
    • 10.1038/sj.onc.1207659, 15122317
    • Salatino M, Schillaci R, Proietti CJ, Carnevale R, Frahm I, Molinolo AA, et al. Inhibition of in vivo breast cancer growth by antisense oligodeoxynucleotides to type I insulin-like growth factor receptor mRNA involves inactivation of ErbBs, PI-3 K/Akt and p42/p44 MAPK signaling pathways but not modulation of progesterone receptor activity. Oncogene 2004, 23:5161-5174. 10.1038/sj.onc.1207659, 15122317.
    • (2004) Oncogene , vol.23 , pp. 5161-5174
    • Salatino, M.1    Schillaci, R.2    Proietti, C.J.3    Carnevale, R.4    Frahm, I.5    Molinolo, A.A.6
  • 8
    • 57749089652 scopus 로고    scopus 로고
    • Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival
    • 10.1158/0008-5472.CAN-08-2755, 19074892
    • Law JH, Habibi G, Hu K, Masoudi H, Wang MY, Stratford AL, et al. Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival. Cancer Res 2008, 68:10238-10246. 10.1158/0008-5472.CAN-08-2755, 19074892.
    • (2008) Cancer Res , vol.68 , pp. 10238-10246
    • Law, J.H.1    Habibi, G.2    Hu, K.3    Masoudi, H.4    Wang, M.Y.5    Stratford, A.L.6
  • 9
    • 69449097339 scopus 로고    scopus 로고
    • Emerging role of insulin-like growth factor receptor inhibitors in oncology: early clinical trial results and future directions
    • 10.1038/onc.2009.172, 19581933
    • Gualberto A, Pollak M. Emerging role of insulin-like growth factor receptor inhibitors in oncology: early clinical trial results and future directions. Oncogene 2009, 28:3009-3021. 10.1038/onc.2009.172, 19581933.
    • (2009) Oncogene , vol.28 , pp. 3009-3021
    • Gualberto, A.1    Pollak, M.2
  • 10
    • 57149127369 scopus 로고    scopus 로고
    • IGF-1 receptor inhibitors in clinical trials--early lessons
    • 10.1007/s10911-008-9104-6, 2728362, 19023648
    • Weroha SJ, Haluska P. IGF-1 receptor inhibitors in clinical trials--early lessons. J Mammary Gland Biol Neoplasia 2008, 13:471-483. 10.1007/s10911-008-9104-6, 2728362, 19023648.
    • (2008) J Mammary Gland Biol Neoplasia , vol.13 , pp. 471-483
    • Weroha, S.J.1    Haluska, P.2
  • 11
    • 0242637268 scopus 로고    scopus 로고
    • Potential therapeutic strategies to interrupt insulin-like growth factor signaling in breast cancer
    • Byron SA, Yee D. Potential therapeutic strategies to interrupt insulin-like growth factor signaling in breast cancer. Semin Oncol 2003, 30:125-132.
    • (2003) Semin Oncol , vol.30 , pp. 125-132
    • Byron, S.A.1    Yee, D.2
  • 12
    • 33947121226 scopus 로고    scopus 로고
    • Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation
    • 10.1038/sj.onc.1209955, 16953219
    • Jones RA, Campbell CI, Gunther EJ, Chodosh LA, Petrik JJ, Khokha R, et al. Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation. Oncogene 2007, 26:1636-1644. 10.1038/sj.onc.1209955, 16953219.
    • (2007) Oncogene , vol.26 , pp. 1636-1644
    • Jones, R.A.1    Campbell, C.I.2    Gunther, E.J.3    Chodosh, L.A.4    Petrik, J.J.5    Khokha, R.6
  • 14
    • 84863727486 scopus 로고    scopus 로고
    • Transgenic IGF-IR overexpression induces mammary tumors with basal-like characteristics while IGF-IR independent mammary tumors express a claudin-low gene signature
    • Franks SE, Campbell CI, Barnett EF, Siwicky MD, Livingstone J, Cory S, et al. Transgenic IGF-IR overexpression induces mammary tumors with basal-like characteristics while IGF-IR independent mammary tumors express a claudin-low gene signature. Oncogene 2011,
    • (2011) Oncogene
    • Franks, S.E.1    Campbell, C.I.2    Barnett, E.F.3    Siwicky, M.D.4    Livingstone, J.5    Cory, S.6
  • 15
    • 33748175142 scopus 로고    scopus 로고
    • Biology of platelet-derived growth factor and its involvement in disease
    • 10.4065/81.9.1241, 16970222
    • Alvarez RH, Kantarjian HM, Cortes JE. Biology of platelet-derived growth factor and its involvement in disease. Mayo Clin Proc 2006, 81:1241-1257. 10.4065/81.9.1241, 16970222.
    • (2006) Mayo Clin Proc , vol.81 , pp. 1241-1257
    • Alvarez, R.H.1    Kantarjian, H.M.2    Cortes, J.E.3
  • 16
    • 2942676788 scopus 로고    scopus 로고
    • The PDGF family: four gene products form five dimeric isoforms
    • 10.1016/j.cytogfr.2004.03.007, 15207811
    • Fredriksson L, Li H, Eriksson U. The PDGF family: four gene products form five dimeric isoforms. Cytokine Growth Factor Rev 2004, 15:197-204. 10.1016/j.cytogfr.2004.03.007, 15207811.
    • (2004) Cytokine Growth Factor Rev , vol.15 , pp. 197-204
    • Fredriksson, L.1    Li, H.2    Eriksson, U.3
  • 17
    • 0346024111 scopus 로고    scopus 로고
    • Biology of platelet-derived growth factors in development
    • 10.1002/bdrc.10030, 14745969
    • Betsholtz C. Biology of platelet-derived growth factors in development. Birth Defects Res C Embryo Today 2003, 69:272-285. 10.1002/bdrc.10030, 14745969.
    • (2003) Birth Defects Res C Embryo Today , vol.69 , pp. 272-285
    • Betsholtz, C.1
  • 18
    • 0038544202 scopus 로고    scopus 로고
    • Platelet-derived growth factor signaling and human cancer
    • 10.5483/BMBRep.2003.36.1.049, 12542975
    • Yu J, Ustach C, Kim HR. Platelet-derived growth factor signaling and human cancer. J Biochem Mol Biol 2003, 36:49-59. 10.5483/BMBRep.2003.36.1.049, 12542975.
    • (2003) J Biochem Mol Biol , vol.36 , pp. 49-59
    • Yu, J.1    Ustach, C.2    Kim, H.R.3
  • 19
    • 0029978211 scopus 로고    scopus 로고
    • Localization of platelet-derived growth factor beta receptor expression in the periepithelial stroma of human breast carcinoma
    • Bhardwaj B, Klassen J, Cossette N, Sterns E, Tuck A, Deeley R, et al. Localization of platelet-derived growth factor beta receptor expression in the periepithelial stroma of human breast carcinoma. Clin Cancer Res 1996, 2:773-782.
    • (1996) Clin Cancer Res , vol.2 , pp. 773-782
    • Bhardwaj, B.1    Klassen, J.2    Cossette, N.3    Sterns, E.4    Tuck, A.5    Deeley, R.6
  • 20
    • 0029039982 scopus 로고
    • Expression of platelet-derived growth factor B-chain and the platelet-derived growth factor receptor beta subunit in human breast tissue and breast carcinoma
    • Coltrera MD, Wang J, Porter PL, Gown AM. Expression of platelet-derived growth factor B-chain and the platelet-derived growth factor receptor beta subunit in human breast tissue and breast carcinoma. Cancer Res 1995, 55:2703-2708.
    • (1995) Cancer Res , vol.55 , pp. 2703-2708
    • Coltrera, M.D.1    Wang, J.2    Porter, P.L.3    Gown, A.M.4
  • 21
    • 33644873490 scopus 로고    scopus 로고
    • Overexpression of platelet-derived growth factor receptor alpha in breast cancer is associated with tumour progression
    • 10.1186/bcr1304, 1242156, 16168125
    • Carvalho I, Milanezi F, Martins A, Reis RM, Schmitt F. Overexpression of platelet-derived growth factor receptor alpha in breast cancer is associated with tumour progression. Breast Cancer Res 2005, 7:R788-R795. 10.1186/bcr1304, 1242156, 16168125.
    • (2005) Breast Cancer Res , vol.7
    • Carvalho, I.1    Milanezi, F.2    Martins, A.3    Reis, R.M.4    Schmitt, F.5
  • 22
    • 33745192635 scopus 로고    scopus 로고
    • Autocrine PDGFR signaling promotes mammary cancer metastasis
    • 10.1172/JCI24652, 1469776, 16741576
    • Jechlinger M, Sommer A, Moriggl R, Seither P, Kraut N, Capodiecci P, et al. Autocrine PDGFR signaling promotes mammary cancer metastasis. J Clin Invest 2006, 116:1561-1570. 10.1172/JCI24652, 1469776, 16741576.
    • (2006) J Clin Invest , vol.116 , pp. 1561-1570
    • Jechlinger, M.1    Sommer, A.2    Moriggl, R.3    Seither, P.4    Kraut, N.5    Capodiecci, P.6
  • 23
    • 0023193815 scopus 로고
    • Possible positive autocrine feedback in the prereplicative phase of human fibroblasts
    • 10.1038/328715a0, 3497351
    • Paulsson Y, Hammacher A, Heldin CH, Westermark B. Possible positive autocrine feedback in the prereplicative phase of human fibroblasts. Nature 1987, 328:715-717. 10.1038/328715a0, 3497351.
    • (1987) Nature , vol.328 , pp. 715-717
    • Paulsson, Y.1    Hammacher, A.2    Heldin, C.H.3    Westermark, B.4
  • 24
    • 51049089793 scopus 로고    scopus 로고
    • Characterization of a novel primary mammary tumor cell line reveals that cyclin D1 is regulated by the type I insulin-like growth factor receptor
    • 10.1158/1541-7786.MCR-07-2157, 18505926
    • Jones RA, Campbell CI, Petrik JJ, Moorehead RA. Characterization of a novel primary mammary tumor cell line reveals that cyclin D1 is regulated by the type I insulin-like growth factor receptor. Mol Cancer Res 2008, 6:819-828. 10.1158/1541-7786.MCR-07-2157, 18505926.
    • (2008) Mol Cancer Res , vol.6 , pp. 819-828
    • Jones, R.A.1    Campbell, C.I.2    Petrik, J.J.3    Moorehead, R.A.4
  • 26
    • 0030612749 scopus 로고    scopus 로고
    • JC-1, but not DiOC6(3) or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells: implications for studies on mitochondrial functionality during apoptosis
    • 10.1016/S0014-5793(97)00669-8, 9247146
    • Salvioli S, Ardizzoni A, Franceschi C, Cossarizza A. JC-1, but not DiOC6(3) or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells: implications for studies on mitochondrial functionality during apoptosis. FEBS Lett 1997, 411:77-82. 10.1016/S0014-5793(97)00669-8, 9247146.
    • (1997) FEBS Lett , vol.411 , pp. 77-82
    • Salvioli, S.1    Ardizzoni, A.2    Franceschi, C.3    Cossarizza, A.4
  • 27
    • 77956922669 scopus 로고    scopus 로고
    • Differential mechanisms of acquired resistance to insulin-like growth factor-i receptor antibody therapy or to a small-molecule inhibitor, BMS-754807, in a human rhabdomyosarcoma model
    • 10.1158/0008-5472.CAN-10-0391, 20807811
    • Huang F, Hurlburt W, Greer A, Reeves KA, Hillerman S, Chang H, et al. Differential mechanisms of acquired resistance to insulin-like growth factor-i receptor antibody therapy or to a small-molecule inhibitor, BMS-754807, in a human rhabdomyosarcoma model. Cancer Res 2010, 70:7221-7231. 10.1158/0008-5472.CAN-10-0391, 20807811.
    • (2010) Cancer Res , vol.70 , pp. 7221-7231
    • Huang, F.1    Hurlburt, W.2    Greer, A.3    Reeves, K.A.4    Hillerman, S.5    Chang, H.6
  • 28
    • 46149104384 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumors
    • 10.1073/pnas.0803383105, 2448846, 18550829
    • Tarn C, Rink L, Merkel E, Flieder D, Pathak H, Koumbi D, et al. Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumors. Proc Natl Acad Sci USA 2008, 105:8387-8392. 10.1073/pnas.0803383105, 2448846, 18550829.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 8387-8392
    • Tarn, C.1    Rink, L.2    Merkel, E.3    Flieder, D.4    Pathak, H.5    Koumbi, D.6
  • 29
    • 0025216650 scopus 로고
    • Differential effects of the various isoforms of platelet-derived growth factor on chemotaxis of fibroblasts, monocytes, and granulocytes
    • 10.1172/JCI114519, 296510, 2155930
    • Siegbahn A, Hammacher A, Westermark B, Heldin CH. Differential effects of the various isoforms of platelet-derived growth factor on chemotaxis of fibroblasts, monocytes, and granulocytes. J Clin Invest 1990, 85:916-920. 10.1172/JCI114519, 296510, 2155930.
    • (1990) J Clin Invest , vol.85 , pp. 916-920
    • Siegbahn, A.1    Hammacher, A.2    Westermark, B.3    Heldin, C.H.4
  • 30
    • 0026753688 scopus 로고
    • Neomycin is a platelet-derived growth factor (PDGF) antagonist that allows discrimination of PDGF alpha- and beta-receptor signals in cells expressing both receptor types
    • Vassbotn FS, Ostman A, Siegbahn A, Holmsen H, Heldin CH. Neomycin is a platelet-derived growth factor (PDGF) antagonist that allows discrimination of PDGF alpha- and beta-receptor signals in cells expressing both receptor types. J Biol Chem 1992, 267:15635-15641.
    • (1992) J Biol Chem , vol.267 , pp. 15635-15641
    • Vassbotn, F.S.1    Ostman, A.2    Siegbahn, A.3    Holmsen, H.4    Heldin, C.H.5
  • 31
    • 0028089005 scopus 로고
    • Membrane ruffling and chemotaxis transduced by the PDGF beta-receptor require the binding site for phosphatidylinositol 3' kinase
    • Wennstrom S, Siegbahn A, Yokote K, Arvidsson AK, Heldin CH, Mori S, et al. Membrane ruffling and chemotaxis transduced by the PDGF beta-receptor require the binding site for phosphatidylinositol 3' kinase. Oncogene 1994, 9:651-660.
    • (1994) Oncogene , vol.9 , pp. 651-660
    • Wennstrom, S.1    Siegbahn, A.2    Yokote, K.3    Arvidsson, A.K.4    Heldin, C.H.5    Mori, S.6
  • 32
    • 79151479321 scopus 로고    scopus 로고
    • Platelet-derived growth factor-D contributes to aggressiveness of breast cancer cells by up-regulating Notch and NF-kappaB signaling pathways
    • 10.1007/s10549-010-0883-2, 20379844
    • Ahmad A, Wang Z, Kong D, Ali R, Ali S, Banerjee S, et al. Platelet-derived growth factor-D contributes to aggressiveness of breast cancer cells by up-regulating Notch and NF-kappaB signaling pathways. Breast Cancer Res Treat 2011, 126:15-25. 10.1007/s10549-010-0883-2, 20379844.
    • (2011) Breast Cancer Res Treat , vol.126 , pp. 15-25
    • Ahmad, A.1    Wang, Z.2    Kong, D.3    Ali, R.4    Ali, S.5    Banerjee, S.6
  • 33
    • 77953024092 scopus 로고    scopus 로고
    • Platelet derived growth factor increases phospholipase D1 but not phospholipase D2 expression via NFkappaB signaling pathway and enhances invasion of breast cancer cells
    • 10.1016/j.canlet.2010.01.031, 20188462
    • Kang DW, Min D. Platelet derived growth factor increases phospholipase D1 but not phospholipase D2 expression via NFkappaB signaling pathway and enhances invasion of breast cancer cells. Cancer Lett 2010, 294:125-133. 10.1016/j.canlet.2010.01.031, 20188462.
    • (2010) Cancer Lett , vol.294 , pp. 125-133
    • Kang, D.W.1    Min, D.2
  • 34
    • 2942670180 scopus 로고    scopus 로고
    • PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma
    • 10.1016/j.cytogfr.2004.03.002, 15207817
    • Ostman A. PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma. Cytokine Growth Factor Rev 2004, 15:275-286. 10.1016/j.cytogfr.2004.03.002, 15207817.
    • (2004) Cytokine Growth Factor Rev , vol.15 , pp. 275-286
    • Ostman, A.1
  • 35
    • 34047127376 scopus 로고    scopus 로고
    • PDGF receptors as targets in tumor treatment
    • Ostman A, Heldin CH. PDGF receptors as targets in tumor treatment. Adv Cancer Res 2007, 97:247-274.
    • (2007) Adv Cancer Res , vol.97 , pp. 247-274
    • Ostman, A.1    Heldin, C.H.2
  • 36
    • 67650500874 scopus 로고    scopus 로고
    • Platelet-derived growth factor-receptor alpha strongly inhibits melanoma growth in vitro and in vivo
    • 2713586, 19649203
    • Faraone D, Aguzzi MS, Toietta G, Facchiano AM, Facchiano F, Magenta A, et al. Platelet-derived growth factor-receptor alpha strongly inhibits melanoma growth in vitro and in vivo. Neoplasia 2009, 11:732-742. 2713586, 19649203.
    • (2009) Neoplasia , vol.11 , pp. 732-742
    • Faraone, D.1    Aguzzi, M.S.2    Toietta, G.3    Facchiano, A.M.4    Facchiano, F.5    Magenta, A.6
  • 37
    • 34547662268 scopus 로고    scopus 로고
    • Overexpression of PDGF-BB decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content
    • 10.1172/JCI31334, 1913488, 17641778
    • McCarty MF, Somcio RJ, Stoeltzing O, Wey J, Fan F, Liu W, et al. Overexpression of PDGF-BB decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content. J Clin Invest 2007, 117:2114-2122. 10.1172/JCI31334, 1913488, 17641778.
    • (2007) J Clin Invest , vol.117 , pp. 2114-2122
    • McCarty, M.F.1    Somcio, R.J.2    Stoeltzing, O.3    Wey, J.4    Fan, F.5    Liu, W.6
  • 38
    • 0032462002 scopus 로고    scopus 로고
    • Evidence for distinct signaling properties and biological responses induced by the PDGF receptor alpha and beta subtypes
    • 10.3109/08977199909002130, 10372961
    • Rosenkranz S, Kazlauskas A. Evidence for distinct signaling properties and biological responses induced by the PDGF receptor alpha and beta subtypes. Growth Factors 1999, 16:201-216. 10.3109/08977199909002130, 10372961.
    • (1999) Growth Factors , vol.16 , pp. 201-216
    • Rosenkranz, S.1    Kazlauskas, A.2
  • 39
    • 0035499454 scopus 로고    scopus 로고
    • Ten years of protein kinase B signalling: a hard Akt to follow
    • 10.1016/S0968-0004(01)01958-2, 11701324
    • Brazil DP, Hemmings BA. Ten years of protein kinase B signalling: a hard Akt to follow. Trends Biochem Sci 2001, 26:657-664. 10.1016/S0968-0004(01)01958-2, 11701324.
    • (2001) Trends Biochem Sci , vol.26 , pp. 657-664
    • Brazil, D.P.1    Hemmings, B.A.2
  • 40
    • 34250788809 scopus 로고    scopus 로고
    • AKT/PKB signaling: navigating downstream
    • 10.1016/j.cell.2007.06.009, 2756685, 17604717
    • Manning BD, Cantley LC. AKT/PKB signaling: navigating downstream. Cell 2007, 129:1261-1274. 10.1016/j.cell.2007.06.009, 2756685, 17604717.
    • (2007) Cell , vol.129 , pp. 1261-1274
    • Manning, B.D.1    Cantley, L.C.2
  • 41
    • 33646253672 scopus 로고    scopus 로고
    • Akt signaling and cancer: surviving but not moving on
    • 10.1158/0008-5472.CAN-06-0743, 16618711
    • Toker A, Yoeli-Lerner M. Akt signaling and cancer: surviving but not moving on. Cancer Res 2006, 66:3963-3966. 10.1158/0008-5472.CAN-06-0743, 16618711.
    • (2006) Cancer Res , vol.66 , pp. 3963-3966
    • Toker, A.1    Yoeli-Lerner, M.2
  • 42
    • 58249101005 scopus 로고    scopus 로고
    • The mechanisms of differential sensitivity to an insulin-like growth factor-1 receptor inhibitor (BMS-536924) and rationale for combining with EGFR/HER2 inhibitors
    • 10.1158/0008-5472.CAN-08-0835, 19117999
    • Huang F, Greer A, Hurlburt W, Han X, Hafezi R, Wittenberg GM, et al. The mechanisms of differential sensitivity to an insulin-like growth factor-1 receptor inhibitor (BMS-536924) and rationale for combining with EGFR/HER2 inhibitors. Cancer Res 2009, 69:161-170. 10.1158/0008-5472.CAN-08-0835, 19117999.
    • (2009) Cancer Res , vol.69 , pp. 161-170
    • Huang, F.1    Greer, A.2    Hurlburt, W.3    Han, X.4    Hafezi, R.5    Wittenberg, G.M.6
  • 43
    • 78751489491 scopus 로고    scopus 로고
    • Drug efflux by breast cancer resistance protein is a mechanism of resistance to the benzimidazole insulin-like growth factor receptor/insulin receptor inhibitor, BMS-536924
    • 10.1158/1535-7163.MCT-10-0438, 21220496
    • Hou X, Huang F, Carboni JM, Flatten K, Asmann YW, Ten EC, et al. Drug efflux by breast cancer resistance protein is a mechanism of resistance to the benzimidazole insulin-like growth factor receptor/insulin receptor inhibitor, BMS-536924. Mol Cancer Ther 2011, 10:117-125. 10.1158/1535-7163.MCT-10-0438, 21220496.
    • (2011) Mol Cancer Ther , vol.10 , pp. 117-125
    • Hou, X.1    Huang, F.2    Carboni, J.M.3    Flatten, K.4    Asmann, Y.W.5    Ten, E.C.6
  • 44
  • 45
    • 80051650773 scopus 로고    scopus 로고
    • Murine mammary tumor cells with a claudin-low genotype
    • 10.1186/1475-2867-11-28, 3170246, 21846397
    • Campbell CI, Thompson DE, Siwicky MD, Moorehead RA. Murine mammary tumor cells with a claudin-low genotype. Cancer Cell International 2011, 11:28. 10.1186/1475-2867-11-28, 3170246, 21846397.
    • (2011) Cancer Cell International , vol.11 , pp. 28
    • Campbell, C.I.1    Thompson, D.E.2    Siwicky, M.D.3    Moorehead, R.A.4
  • 46
    • 34548863946 scopus 로고    scopus 로고
    • Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors
    • 10.1186/gb-2007-8-5-r76, 1929138, 17493263
    • Herschkowitz JI, Simin K, Weigman VJ, Mikaelian I, Usary J, Hu Z, et al. Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol 2007, 8:R76. 10.1186/gb-2007-8-5-r76, 1929138, 17493263.
    • (2007) Genome Biol , vol.8
    • Herschkowitz, J.I.1    Simin, K.2    Weigman, V.J.3    Mikaelian, I.4    Usary, J.5    Hu, Z.6
  • 47
    • 78049308800 scopus 로고    scopus 로고
    • Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer
    • 10.1186/bcr2635, 3096954, 20813035
    • Prat A, Parker JS, Karginova O, Fan C, Livasy C, Herschkowitz JI, et al. Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer. Breast Cancer Res 2010, 12:R68. 10.1186/bcr2635, 3096954, 20813035.
    • (2010) Breast Cancer Res , vol.12
    • Prat, A.1    Parker, J.S.2    Karginova, O.3    Fan, C.4    Livasy, C.5    Herschkowitz, J.I.6


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