Cbl negatively regulates erythropoietin-induced growth and survival signaling through the proteasomal degradation of src kinase

Blood Cells, Molecules, and Diseases

Volumn 53, Issue 4, 2014, Pages 211-218

  Shintani, Takamichi ^a   Ohara Waki, Fusako ^b   Kitanaka, Akira ^c   Tanaka, Terukazu ^a   Kubota, Yoshitsugu ^a  

^a KAGAWA UNIVERSITY   (Japan)

^b TAKAMATSU RED CROSS HOSPITAL   (Japan)

^c UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

Cbl; Erythropoietin; Proteasome; Src; Ubiquitination

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CBL PROTEIN; ERYTHROPOIETIN; JANUS KINASE 2; PROTEIN TYROSINE KINASE; SMALL INTERFERING RNA; 4-AMINO-5-(4-METHYLPHENYL)-7-(TERT-BUTYL)PYRAZOLO(3,4-D)PYRIMIDINE; AMMONIUM CHLORIDE; ANTINEOPLASTIC AGENT; BENZYLOXYCARBONYLLEUCYL-LEUCYL-LEUCINE ALDEHYDE; CBL PROTEIN, HUMAN; EPO PROTEIN, HUMAN; JAK2 PROTEIN, HUMAN; LEUPEPTIN; PROTEASOME; PROTEIN KINASE P60; PYRAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE;

APOPTOSIS; ARTICLE; CBL GENE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEGRADATION; ERYTHROLEUKEMIA CELL; EXPRESSION VECTOR; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INHIBITION KINETICS; NORMAL HUMAN; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UBIQUITINATION; ANTAGONISTS AND INHIBITORS; CYTOLOGY; DRUG EFFECTS; GENETICS; LYMPHOCYTE; METABOLISM; PHOSPHORYLATION; TUMOR CELL LINE;

AMMONIUM CHLORIDE; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; ERYTHROPOIETIN; GENE EXPRESSION REGULATION; HUMANS; JANUS KINASE 2; LEUPEPTINS; LYMPHOCYTES; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-CBL; PROTO-ONCOGENE PROTEINS PP60(C-SRC); PYRAZOLES; PYRIMIDINES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; UBIQUITINATION;

EID: 84908113535     PISSN: 10799796     EISSN: 10960961     Source Type: Journal    
DOI: 10.1016/j.bcmd.2014.06.005     Document Type: Article

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