메뉴 건너뛰기




Volumn 32, Issue 10, 2014, Pages 2596-2604

Neural stem cells differentiated from iPS cells spontaneously regain pluripotency

Author keywords

Exogenous factors; Induced pluripotent stem cells; Neural stem cells; Pluripotent stem cells; Reprogramming

Indexed keywords

DNA METHYLTRANSFERASE; DOXYCYCLINE; GREEN FLUORESCENT PROTEIN; NESTIN; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; DNA (CYTOSINE 5) METHYLTRANSFERASE;

EID: 84908103530     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.1757     Document Type: Article
Times cited : (53)

References (44)
  • 1
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006;126:663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 2
    • 34249909232 scopus 로고    scopus 로고
    • Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution
    • Maherali N, Sridharan R, Xie W et al. Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell 2007;1:55-70.
    • (2007) Cell Stem Cell , vol.1 , pp. 55-70
    • Maherali, N.1    Sridharan, R.2    Xie, W.3
  • 3
    • 34249880066 scopus 로고    scopus 로고
    • Generation of germline-competent induced pluripotent stem cells
    • Okita K, Ichisaka T, Yamanaka S. Generation of germline-competent induced pluripotent stem cells. Nature 2007;448:313-317.
    • (2007) Nature , vol.448 , pp. 313-317
    • Okita, K.1    Ichisaka, T.2    Yamanaka, S.3
  • 4
    • 41949134533 scopus 로고    scopus 로고
    • Generation of pluripotent stem cells from adult mouse liver and stomach cells
    • Aoi T, Yae K, Nakagawa M et al. Generation of pluripotent stem cells from adult mouse liver and stomach cells. Science 2008; 321:699-702.
    • (2008) Science , vol.321 , pp. 699-702
    • Aoi, T.1    Yae, K.2    Nakagawa, M.3
  • 5
    • 38049028459 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
    • Nakagawa M, Koyanagi M, Tanabe K et al. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol 2008;26: 101-106.
    • (2008) Nat Biotechnol , vol.26 , pp. 101-106
    • Nakagawa, M.1    Koyanagi, M.2    Tanabe, K.3
  • 6
    • 34249908901 scopus 로고    scopus 로고
    • In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
    • Wernig M, Meissner A, Foreman R et al. In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 2007; 448:318-324.
    • (2007) Nature , vol.448 , pp. 318-324
    • Wernig, M.1    Meissner, A.2    Foreman, R.3
  • 7
    • 64749111225 scopus 로고    scopus 로고
    • Virus-free induction of pluripotency and subsequent excision of reprogramming factors
    • Kaji K, Norrby K, Paca A et al. Virus-free induction of pluripotency and subsequent excision of reprogramming factors. Nature 2009;458:771-775.
    • (2009) Nature , vol.458 , pp. 771-775
    • Kaji, K.1    Norrby, K.2    Paca, A.3
  • 8
    • 77958536106 scopus 로고    scopus 로고
    • Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA
    • Warren L, Manos PD, Ahfeldt T et al. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 2010;7:618-630.
    • (2010) Cell Stem Cell , vol.7 , pp. 618-630
    • Warren, L.1    Manos, P.D.2    Ahfeldt, T.3
  • 9
    • 65649116572 scopus 로고    scopus 로고
    • Human induced pluripotent stem cells free of vector and transgene sequences
    • Yu J, Hu K, Smuga-Otto K et al. Human induced pluripotent stem cells free of vector and transgene sequences. Science 2009;324: 797-801.
    • (2009) Science , vol.324 , pp. 797-801
    • Yu, J.1    Hu, K.2    Smuga-Otto, K.3
  • 10
    • 66049143859 scopus 로고    scopus 로고
    • Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins
    • Kim D, Kim CH, Moon JI et al. Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell 2009;4:472-476.
    • (2009) Cell Stem Cell , vol.4 , pp. 472-476
    • Kim, D.1    Kim, C.H.2    Moon, J.I.3
  • 11
    • 66049135249 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells using recombinant proteins
    • Zhou H, Wu S, Joo JY et al. Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 2009;4: 381-384.
    • (2009) Cell Stem Cell , vol.4 , pp. 381-384
    • Zhou, H.1    Wu, S.2    Joo, J.Y.3
  • 12
    • 84881256653 scopus 로고    scopus 로고
    • Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds
    • Hou P, Li Y, Zhang X et al. Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds. Science 2013; 341:651-654.
    • (2013) Science , vol.341 , pp. 651-654
    • Hou, P.1    Li, Y.2    Zhang, X.3
  • 13
    • 38649094609 scopus 로고    scopus 로고
    • Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells
    • Brambrink T, Foreman R, Welstead GG et al. Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells. Cell Stem Cell 2008;2: 151-159.
    • (2008) Cell Stem Cell , vol.2 , pp. 151-159
    • Brambrink, T.1    Foreman, R.2    Welstead, G.G.3
  • 14
    • 55849117368 scopus 로고    scopus 로고
    • Generation of mouse induced pluripotent stem cells without viral vectors
    • Okita K, Nakagawa M, Hyenjong H et al. Generation of mouse induced pluripotent stem cells without viral vectors. Science 2008;322:949-953.
    • (2008) Science , vol.322 , pp. 949-953
    • Okita, K.1    Nakagawa, M.2    Hyenjong, H.3
  • 15
    • 84893155560 scopus 로고    scopus 로고
    • Intrachromosomal looping is required for activation of endogenous pluripotency genes during reprogramming
    • Zhang H, Jiao W, Sun L et al. Intrachromosomal looping is required for activation of endogenous pluripotency genes during reprogramming. Cell Stem Cell 2013;13:30-35.
    • (2013) Cell Stem Cell , vol.13 , pp. 30-35
    • Zhang, H.1    Jiao, W.2    Sun, L.3
  • 16
    • 84887852466 scopus 로고    scopus 로고
    • Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming
    • Apostolou E, Ferrari F, Walsh RM et al. Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming. Cell Stem Cell 2013;12: 699-712.
    • (2013) Cell Stem Cell , vol.12 , pp. 699-712
    • Apostolou, E.1    Ferrari, F.2    Walsh, R.M.3
  • 17
    • 68649109365 scopus 로고    scopus 로고
    • Regulatory circuits underlying pluripotency and reprogramming
    • Do JT, Scholer HR. Regulatory circuits underlying pluripotency and reprogramming. Trends Pharmacol Sci 2009;30:296-302.
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 296-302
    • Do, J.T.1    Scholer, H.R.2
  • 18
    • 39149130361 scopus 로고    scopus 로고
    • Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming
    • Jaenisch R, Young R. Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell 2008;132:567-582.
    • (2008) Cell , vol.132 , pp. 567-582
    • Jaenisch, R.1    Young, R.2
  • 19
    • 33645381936 scopus 로고    scopus 로고
    • The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
    • Loh YH, Wu Q, Chew JL et al. The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet 2006;38:431-440.
    • (2006) Nat Genet , vol.38 , pp. 431-440
    • Loh, Y.H.1    Wu, Q.2    Chew, J.L.3
  • 20
    • 33845229131 scopus 로고    scopus 로고
    • Transgene expression and RNA interference in embryonic stem cells
    • Zaehres H, Daley GQ. Transgene expression and RNA interference in embryonic stem cells. Methods Enzymol 2006;420:49-64.
    • (2006) Methods Enzymol , vol.420 , pp. 49-64
    • Zaehres, H.1    Daley, G.Q.2
  • 21
    • 74049138336 scopus 로고    scopus 로고
    • A reprogrammable mouse strain from gene-targeted embryonic stem cells
    • Stadtfeld M, Maherali N, Borkent M et al. A reprogrammable mouse strain from gene-targeted embryonic stem cells. Nat Methods 2010;7:53-55.
    • (2010) Nat Methods , vol.7 , pp. 53-55
    • Stadtfeld, M.1    Maherali, N.2    Borkent, M.3
  • 22
    • 84871586080 scopus 로고    scopus 로고
    • A molecular roadmap of reprogramming somatic cells into iPS cells
    • Polo JM, Anderssen E, Walsh RM et al. A molecular roadmap of reprogramming somatic cells into iPS cells. Cell 2012;151:1617-1632.
    • (2012) Cell , vol.151 , pp. 1617-1632
    • Polo, J.M.1    Anderssen, E.2    Walsh, R.M.3
  • 23
    • 84880009647 scopus 로고    scopus 로고
    • Conversion of genomic imprinting by reprogramming and redifferentiation
    • Kim MJ, Choi HW, Jang HJ et al. Conversion of genomic imprinting by reprogramming and redifferentiation. J Cell Sci 2013; 126:2516-2524.
    • (2013) J Cell Sci , vol.126 , pp. 2516-2524
    • Kim, M.J.1    Choi, H.W.2    Jang, H.J.3
  • 24
    • 0023150598 scopus 로고
    • HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells
    • Hooper M, Hardy K, Handyside A et al. HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells. Nature 1987;326:292-295.
    • (1987) Nature , vol.326 , pp. 292-295
    • Hooper, M.1    Hardy, K.2    Handyside, A.3
  • 25
    • 59349108302 scopus 로고    scopus 로고
    • Oct4- induced pluripotency in adult neural stem cells
    • Kim JB, Sebastiano V, Wu G et al. Oct4- induced pluripotency in adult neural stem cells. Cell 2009;136:411-419.
    • (2009) Cell , vol.136 , pp. 411-419
    • Kim, J.B.1    Sebastiano, V.2    Wu, G.3
  • 26
    • 54949115497 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with smallmolecule compounds
    • Shi Y, Desponts C, Do JT et al. Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with smallmolecule compounds. Cell Stem Cell 2008;3: 568-574.
    • (2008) Cell Stem Cell , vol.3 , pp. 568-574
    • Shi, Y.1    Desponts, C.2    Do, J.T.3
  • 27
    • 73349126088 scopus 로고    scopus 로고
    • Generation of parthenogenetic induced pluripotent stem cells from parthenogenetic neural stem cells
    • Do JT, Joo JY, Han DW et al. Generation of parthenogenetic induced pluripotent stem cells from parthenogenetic neural stem cells. Stem Cells 2009;27:2962-2968.
    • (2009) Stem Cells , vol.27 , pp. 2962-2968
    • Do, J.T.1    Joo, J.Y.2    Han, D.W.3
  • 28
    • 24944484633 scopus 로고    scopus 로고
    • Niche-independent symmetrical self-renewal of a mammalian tissue stem cell
    • Conti L, Pollard SM, Gorba T et al. Niche-independent symmetrical self-renewal of a mammalian tissue stem cell. PLoS Biol 2005;3:e283.
    • (2005) PLoS Biol , vol.3 , pp. e283
    • Conti, L.1    Pollard, S.M.2    Gorba, T.3
  • 29
    • 33847275530 scopus 로고    scopus 로고
    • Nuclear reprogramming of cloned embryos and its implications for therapeutic cloning
    • Yang X, Smith SL, Tian XC et al. Nuclear reprogramming of cloned embryos and its implications for therapeutic cloning. Nat Genet 2007;39:295-302.
    • (2007) Nat Genet , vol.39 , pp. 295-302
    • Yang, X.1    Smith, S.L.2    Tian, X.C.3
  • 30
    • 79957613988 scopus 로고    scopus 로고
    • Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors
    • Kim J, Lengner CJ, Kirak O et al. Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors. Stem Cells 2011;29:992-1000.
    • (2011) Stem Cells , vol.29 , pp. 992-1000
    • Kim, J.1    Lengner, C.J.2    Kirak, O.3
  • 31
    • 0034904598 scopus 로고    scopus 로고
    • Silencing of gene expression: Implications for design of retrovirus vectors
    • Pannell D, Ellis J. Silencing of gene expression: Implications for design of retrovirus vectors. Rev Med Virol 2001;11:205-217.
    • (2001) Rev Med Virol , vol.11 , pp. 205-217
    • Pannell, D.1    Ellis, J.2
  • 32
    • 22944464097 scopus 로고    scopus 로고
    • Retrovirus silencing and vector design: Relevance to normal and cancer stem cells?
    • Ellis J, Yao S. Retrovirus silencing and vector design: Relevance to normal and cancer stem cells? Curr Gene Ther 2005;5:367-373.
    • (2005) Curr Gene Ther , vol.5 , pp. 367-373
    • Ellis, J.1    Yao, S.2
  • 33
    • 0034329445 scopus 로고    scopus 로고
    • Retrovirus vector silencing is de novo methylase independent and marked by a repressive histone code
    • Pannell D, Osborne CS, Yao S et al. Retrovirus vector silencing is de novo methylase independent and marked by a repressive histone code. EMBO J 2000;19:5884-5894.
    • (2000) EMBO J , vol.19 , pp. 5884-5894
    • Pannell, D.1    Osborne, C.S.2    Yao, S.3
  • 34
    • 3042732990 scopus 로고    scopus 로고
    • Retrovirus silencing, variegation, extinction, and memory are controlled by a dynamic interplay of multiple epigenetic modifications
    • Yao S, Sukonnik T, Kean T et al. Retrovirus silencing, variegation, extinction, and memory are controlled by a dynamic interplay of multiple epigenetic modifications. Mol Ther 2004;10:27-36.
    • (2004) Mol Ther , vol.10 , pp. 27-36
    • Yao, S.1    Sukonnik, T.2    Kean, T.3
  • 35
    • 33947261036 scopus 로고    scopus 로고
    • Real-time fluorescence tracking of dynamic transgene variegation in stem cells
    • Ramunas J, Montgomery HJ, Kelly L et al. Real-time fluorescence tracking of dynamic transgene variegation in stem cells. Mol Ther 2007;15:810-817.
    • (2007) Mol Ther , vol.15 , pp. 810-817
    • Ramunas, J.1    Montgomery, H.J.2    Kelly, L.3
  • 36
    • 39149115929 scopus 로고    scopus 로고
    • Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse
    • Stadtfeld M, Maherali N, Breault DT et al. Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse. Cell Stem Cell 2008;2:230-240.
    • (2008) Cell Stem Cell , vol.2 , pp. 230-240
    • Stadtfeld, M.1    Maherali, N.2    Breault, D.T.3
  • 37
    • 64749083939 scopus 로고    scopus 로고
    • PiggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
    • Woltjen K, Michael IP, Mohseni P et al. piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature 2009;458:766-770.
    • (2009) Nature , vol.458 , pp. 766-770
    • Woltjen, K.1    Michael, I.P.2    Mohseni, P.3
  • 38
    • 44649086468 scopus 로고    scopus 로고
    • Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells
    • Liang J, Wan M, Zhang Y et al. Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells. Nat Cell Biol 2008;10:731-739.
    • (2008) Nat Cell Biol , vol.10 , pp. 731-739
    • Liang, J.1    Wan, M.2    Zhang, Y.3
  • 39
    • 75849152244 scopus 로고    scopus 로고
    • Neuropotent self-renewing neural stem (NS) cells derived from mouse induced pluripotent stem (iPS) cells
    • Onorati M, Camnasio S, Binetti M et al. Neuropotent self-renewing neural stem (NS) cells derived from mouse induced pluripotent stem (iPS) cells. Mol Cell Neurosci 2010;43:287-295.
    • (2010) Mol Cell Neurosci , vol.43 , pp. 287-295
    • Onorati, M.1    Camnasio, S.2    Binetti, M.3
  • 40
    • 68249087053 scopus 로고    scopus 로고
    • Variation in the safety of induced pluripotent stem cell lines
    • Miura K, Okada Y, Aoi T et al. Variation in the safety of induced pluripotent stem cell lines. Nat Biotechnol 2009;27:743-745.
    • (2009) Nat Biotechnol , vol.27 , pp. 743-745
    • Miura, K.1    Okada, Y.2    Aoi, T.3
  • 41
    • 0020048308 scopus 로고
    • De novo methylation and expression of retroviral genomes during mouse embryogenesis
    • Jahner D, Stuhlmann H, Stewart CL et al. De novo methylation and expression of retroviral genomes during mouse embryogenesis. Nature 1982;298:623-628.
    • (1982) Nature , vol.298 , pp. 623-628
    • Jahner, D.1    Stuhlmann, H.2    Stewart, C.L.3
  • 42
    • 0028230779 scopus 로고
    • Lack of expression from a retroviral vector after transduction of murine hematopoietic stem cells is associated with methylation in vivo
    • Challita PM, Kohn DB. Lack of expression from a retroviral vector after transduction of murine hematopoietic stem cells is associated with methylation in vivo. Proc Natl Acad Sci USA 1994;91:2567-2571.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2567-2571
    • Challita, P.M.1    Kohn, D.B.2
  • 43
    • 0011078712 scopus 로고
    • De novo methylation, expression, and infectivity of retroviral genomes introduced into embryonal carcinoma cells
    • Stewart CL, Stuhlmann H, Jahner D et al. De novo methylation, expression, and infectivity of retroviral genomes introduced into embryonal carcinoma cells. Proc Natl Acad Sci USA 1982;79:4098-4102.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 4098-4102
    • Stewart, C.L.1    Stuhlmann, H.2    Jahner, D.3
  • 44
    • 0020503308 scopus 로고
    • Independent mechanisms involved in suppression of the Moloney leukemia virus genome during differentiation of murine teratocarcinoma cells
    • Niwa O, Yokota Y, Ishida H et al. Independent mechanisms involved in suppression of the Moloney leukemia virus genome during differentiation of murine teratocarcinoma cells. Cell 1983;32:1105-1113.
    • (1983) Cell , vol.32 , pp. 1105-1113
    • Niwa, O.1    Yokota, Y.2    Ishida, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.