Upregulated ROS production induced by the proteasome inhibitor MG-132 on XBP1 gene expression and cell apoptosis in Tca-8113 cells

Biomedicine and Pharmacotherapy

Volumn 68, Issue 6, 2014, Pages 709-713

  Chen, Hai ying ^a   Ren, Xiao yan ^a   Wang, Wei hua ^a   Zhang, Ying xin ^a   Chen, Shuang feng ^a   Zhang, Bin ^a   Wang, Le xin ^b  

^a LIAOCHENG PEOPLE'S HOSPITAL   (China)

^b CHARLES STURT UNIVERSITY   (Australia)

Author keywords

Apoptosis; ER stress; MG 132; Reactive oxygen species; Tca 8113 cells

Indexed keywords

ACETYLCYSTEINE; APOPTOSIS SIGNAL REGULATING KINASE 1; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; PROTEIN C JUN; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; X BOX BINDING PROTEIN 1; BENZYLOXYCARBONYLLEUCYL-LEUCYL-LEUCINE ALDEHYDE; DNA BINDING PROTEIN; LEUPEPTIN; PROTEASOME INHIBITOR; REGULATORY FACTOR X TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; IMMUNOCYTOCHEMISTRY; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA CELL LINE; TONGUE CARCINOMA; WESTERN BLOTTING; BIOSYNTHESIS; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; HUMAN; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE; UPREGULATION;

APOPTOSIS; CELL LINE, TUMOR; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LEUPEPTINS; PROTEASOME INHIBITORS; REACTIVE OXYGEN SPECIES; TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 84908093424     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2014.07.011     Document Type: Article

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