-
1
-
-
0033912062
-
Towards the Non-Stick Egg: Designing Fluorous Proteins
-
Marsh, E. N. G. Towards the Non-Stick Egg: Designing Fluorous Proteins Chem. Biol. 2000, 7, R153-R157
-
(2000)
Chem. Biol.
, vol.7
, pp. 153-R157
-
-
Marsh, E.N.G.1
-
3
-
-
0038372081
-
Fluorous Biphase Chemistry
-
Horvath, I. T. Fluorous Biphase Chemistry Acc. Chem. Res. 1998, 31, 641-650
-
(1998)
Acc. Chem. Res.
, vol.31
, pp. 641-650
-
-
Horvath, I.T.1
-
4
-
-
0034838165
-
Self-Association and Membrane-Binding Behavior of Melittins Containing Trifluoroleucine
-
Niemz, A.; Tirrell, D. A. Self-Association and Membrane-Binding Behavior of Melittins Containing Trifluoroleucine J. Am. Chem. Soc. 2001, 123, 7407-7413
-
(2001)
J. Am. Chem. Soc.
, vol.123
, pp. 7407-7413
-
-
Niemz, A.1
Tirrell, D.A.2
-
5
-
-
0035814931
-
Stabilization of Coiled-Coil Peptide Domains by Introduction of Trifluoroleucine
-
Tang, Y.; Ghirlanda, G.; Vaidehi, N.; Kua, J.; Mainz, D. T.; Goddard, W. A.; DeGrado, W. F.; Tirrell, D. A. Stabilization of Coiled-Coil Peptide Domains by Introduction of Trifluoroleucine Biochemistry 2001, 40, 2790-2796
-
(2001)
Biochemistry
, vol.40
, pp. 2790-2796
-
-
Tang, Y.1
Ghirlanda, G.2
Vaidehi, N.3
Kua, J.4
Mainz, D.T.5
Goddard, W.A.6
Degrado, W.F.7
Tirrell, D.A.8
-
6
-
-
7444241366
-
De Novo Design of Defined Helical Bundles in Membrane Environments
-
Bilgicer, B.; Kumar, K. De Novo Design of Defined Helical Bundles in Membrane Environments Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 15324-15329
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 15324-15329
-
-
Bilgicer, B.1
Kumar, K.2
-
7
-
-
33746320232
-
Fluorine in a Native Protein Environment - How the Spatial Demand and Polarity of Fluoroalkyl Groups Affect Protein Folding
-
Jackel, C.; Salwiczek, M.; Koksch, B. Fluorine in a Native Protein Environment-How the Spatial Demand and Polarity of Fluoroalkyl Groups Affect Protein Folding Angew. Chem., Int. Ed. 2006, 45, 4198-4203
-
(2006)
Angew. Chem., Int. Ed.
, vol.45
, pp. 4198-4203
-
-
Jackel, C.1
Salwiczek, M.2
Koksch, B.3
-
8
-
-
34548398596
-
Solution Structure of a Small Protein Containing a Fluorinated Side Chain in the Core
-
Cornilescu, G.; Hadley, E. B.; Woll, M. G.; Markley, J. L.; Gellman, S. H.; Cornilescu, C. C. Solution Structure of a Small Protein Containing a Fluorinated Side Chain in the Core Protein Sci. 2007, 16, 14-19
-
(2007)
Protein Sci.
, vol.16
, pp. 14-19
-
-
Cornilescu, G.1
Hadley, E.B.2
Woll, M.G.3
Markley, J.L.4
Gellman, S.H.5
Cornilescu, C.C.6
-
9
-
-
0041708049
-
Stereoelectronic Effects on Collagen Stability: The Dichotomy of 4-Fluoroproline Diastereomers
-
Hodges, J. A.; Raines, R. T. Stereoelectronic Effects on Collagen Stability: The Dichotomy of 4-Fluoroproline Diastereomers J. Am Chem Soc. 2003, 125, 9262-9263
-
(2003)
J. Am Chem Soc.
, vol.125
, pp. 9262-9263
-
-
Hodges, J.A.1
Raines, R.T.2
-
10
-
-
33845456590
-
Helix Propensity of Highly Fluorinated Amino Acids
-
Chiu, H. P.; Suzuki, Y.; Gullickson, D.; Ahmad, R.; Kokona, B.; Fairman, R.; Cheng, R. P. Helix Propensity of Highly Fluorinated Amino Acids J. Am. Chem. Soc. 2006, 128, 15556-15557
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 15556-15557
-
-
Chiu, H.P.1
Suzuki, Y.2
Gullickson, D.3
Ahmad, R.4
Kokona, B.5
Fairman, R.6
Cheng, R.P.7
-
11
-
-
70349318199
-
Fluorine-A New Element in the Design of Membrane-Active Peptides
-
Marsh, E. N. G.; Buer, B. C.; Ramamoorthy, A. Fluorine-A New Element in the Design of Membrane-Active Peptides Mol. BioSyst. 2009, 5, 1143-1147
-
(2009)
Mol. BioSyst.
, vol.5
, pp. 1143-1147
-
-
Marsh, E.N.G.1
Buer, B.C.2
Ramamoorthy, A.3
-
12
-
-
79959927774
-
Using Fluorine Nuclear Magnetic Resonance to Probe Changes in the Structure and Dynamics of Membrane-Active Peptides Interacting with Lipid Bilayers
-
Suzuki, Y.; Buer, B. C.; Al-Hashimi, H. M.; Marsh, E. N. G. Using Fluorine Nuclear Magnetic Resonance To Probe Changes in the Structure and Dynamics of Membrane-Active Peptides Interacting with Lipid Bilayers Biochemistry 2011, 50, 5979-5987
-
(2011)
Biochemistry
, vol.50
, pp. 5979-5987
-
-
Suzuki, Y.1
Buer, B.C.2
Al-Hashimi, H.M.3
Marsh, E.N.G.4
-
13
-
-
77954755663
-
Using Fluorine Nuclear Magnetic Resonance to Probe the Interaction of Membrane-Active Peptides with the Lipid Bilayer
-
Buer, B. C.; Chugh, J.; Al-Hashimi, H. M.; Marsh, E. N. G. Using Fluorine Nuclear Magnetic Resonance to Probe the Interaction of Membrane-Active Peptides with the Lipid Bilayer Biochemistry 2010, 49, 5760-5765
-
(2010)
Biochemistry
, vol.49
, pp. 5760-5765
-
-
Buer, B.C.1
Chugh, J.2
Al-Hashimi, H.M.3
Marsh, E.N.G.4
-
14
-
-
84876420343
-
19F NMR Reporter for Peptide-Membrane Interactions in Solution
-
19F NMR Reporter for Peptide-Membrane Interactions in Solution J. Pept. Sci. 2013, 19, 308-314
-
(2013)
J. Pept. Sci.
, vol.19
, pp. 308-314
-
-
Buer, B.C.1
Levin, B.J.2
Marsh, E.N.G.3
-
16
-
-
84875459494
-
19F NMR
-
19F NMR Biochemistry 2013, 52, 1903-1912
-
(2013)
Biochemistry
, vol.52
, pp. 1903-1912
-
-
Suzuki, Y.1
Brender, J.R.2
Soper, M.T.3
Krishnamoorthy, J.4
Zhou, Y.5
Ruotolo, B.T.6
Kotov, N.A.7
Ramamoorthy, A.8
Marsh, E.N.G.9
-
17
-
-
0037191625
-
A Short and Efficient Synthesis of l -5,5,5,5′,5′,5′-Hexafluoroleucine from N -Cbz- l -Serine
-
Anderson, J. T.; Toogood, P. L.; Marsh, E. N. G. A Short and Efficient Synthesis of l -5,5,5,5′,5′,5′-Hexafluoroleucine from N -Cbz- l -Serine Org. Lett. 2002, 4, 4281-4283
-
(2002)
Org. Lett.
, vol.4
, pp. 4281-4283
-
-
Anderson, J.T.1
Toogood, P.L.2
Marsh, E.N.G.3
-
18
-
-
0035799841
-
A Novel Synthesis of Enantiomerically Pure 5,5,5,5 ′,5 ′,5 ′-Hexafluoroleucine
-
Xing, X. C.; Fichera, A.; Kumar, K. A Novel Synthesis of Enantiomerically Pure 5,5,5,5 ′,5 ′,5 ′-Hexafluoroleucine Org. Lett. 2001, 3, 1285-1286
-
(2001)
Org. Lett.
, vol.3
, pp. 1285-1286
-
-
Xing, X.C.1
Fichera, A.2
Kumar, K.3
-
19
-
-
38349124527
-
Chemoenzymatic Synthesis of (S)-Hexafluoroleucine and (S)-Tetrafluoroleucine
-
Chiu, H.-P.; Cheng, R. P. Chemoenzymatic Synthesis of (S)-Hexafluoroleucine and (S)-Tetrafluoroleucine Org. Lett. 2007, 9, 5517-5520
-
(2007)
Org. Lett.
, vol.9
, pp. 5517-5520
-
-
Chiu, H.-P.1
Cheng, R.P.2
-
20
-
-
0037183472
-
Attenuation of the Editing Activity of the Escherichia coli Leucyl-tRNA Synthetase Allows Incorporation of Novel Amino Acids into Proteins in Vivo
-
Tang, Y.; Tirrell, D. A. Attenuation of the Editing Activity of the Escherichia coli Leucyl-tRNA Synthetase Allows Incorporation of Novel Amino Acids into Proteins in Vivo Biochemistry 2002, 41, 10635-10645
-
(2002)
Biochemistry
, vol.41
, pp. 10635-10645
-
-
Tang, Y.1
Tirrell, D.A.2
-
21
-
-
0029899119
-
Controlling Topology and Native-Like Behavior of de Novo- Designed Peptides: Design and Characterization of Antiparallel Four-Stranded Coiled Coils
-
Betz, S. F.; DeGrado, W. F. Controlling Topology and Native-Like Behavior of De Novo- Designed Peptides: Design and Characterization of Antiparallel Four-Stranded Coiled Coils Biochemistry 1996, 35, 6955-6962
-
(1996)
Biochemistry
, vol.35
, pp. 6955-6962
-
-
Betz, S.F.1
Degrado, W.F.2
-
22
-
-
0033694923
-
De Novo Design of Helical Bundles as Models for Understanding Protein Folding and Function
-
Hill, R. B.; Raleigh, D. P.; Lombardi, A.; Degrado, W. F. De Novo Design of Helical Bundles as Models for Understanding Protein Folding and Function Acc. Chem. Res. 2000, 33, 745-754
-
(2000)
Acc. Chem. Res.
, vol.33
, pp. 745-754
-
-
Hill, R.B.1
Raleigh, D.P.2
Lombardi, A.3
Degrado, W.F.4
-
23
-
-
11144320703
-
Fluorous Effect in Proteins: De Novo Design and Characterization of a Four-Alpha-Helix Bundle Protein Containing Hexafluoroleucine
-
Lee, K.-H.; Lee, H.-Y.; Slutsky, M. S.; Anderson, J. T.; Marsh, E. N. G. Fluorous Effect in Proteins: De Novo Design and Characterization of a Four-Alpha-Helix Bundle Protein Containing Hexafluoroleucine Biochemistry 2004, 43, 16277-16284
-
(2004)
Biochemistry
, vol.43
, pp. 16277-16284
-
-
Lee, K.-H.1
Lee, H.-Y.2
Slutsky, M.S.3
Anderson, J.T.4
Marsh, E.N.G.5
-
24
-
-
70449562250
-
Engineering Protein Stability and Specificity Using Fluorous Amino Acids: The Importance of Packing Effects
-
Buer, B. C.; de la Salud-Bea, R.; Al Hashimi, H. M.; Marsh, E. N. G. Engineering Protein Stability and Specificity Using Fluorous Amino Acids: The Importance of Packing Effects Biochemistry 2009, 48, 10810-10817
-
(2009)
Biochemistry
, vol.48
, pp. 10810-10817
-
-
Buer, B.C.1
De La Salud-Bea, R.2
Al Hashimi, H.M.3
Marsh, E.N.G.4
-
25
-
-
30744471668
-
Modulating Protein Structure with Fluorous Amino Acids: Increased Stability and Native-Like Structure Conferred on a 4-Helix Bundle Protein by Hexafluoroleucine
-
Lee, H. Y.; Lee, K. H.; Al-Hashimi, H. M.; Marsh, E. N. G. Modulating Protein Structure with Fluorous Amino Acids: Increased Stability and Native-Like Structure Conferred on a 4-Helix Bundle Protein by Hexafluoroleucine J. Am. Chem. Soc. 2006, 128, 337-343
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 337-343
-
-
Lee, H.Y.1
Lee, K.H.2
Al-Hashimi, H.M.3
Marsh, E.N.G.4
-
26
-
-
84864697431
-
Influence of Fluorination on the Thermodynamics of Protein Folding
-
Buer, B. C.; Levin, B. J.; Marsh, E. N. G. Influence of Fluorination on the Thermodynamics of Protein Folding J. Am. Chem. Soc. 2012, 134, 13027-13034
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 13027-13034
-
-
Buer, B.C.1
Levin, B.J.2
Marsh, E.N.G.3
-
28
-
-
0031029886
-
Fluorous Synthesis: A Fluorous-Phase Strategy for Improving Separation Efficiency in Organic Synthesis
-
Studer, A.; Hadida, S.; Ferritto, R.; Kim, S. Y.; Jeger, P.; Wipf, P.; Curran, D. P. Fluorous Synthesis: A Fluorous-Phase Strategy for Improving Separation Efficiency in Organic Synthesis Science 1997, 275, 823-826
-
(1997)
Science
, vol.275
, pp. 823-826
-
-
Studer, A.1
Hadida, S.2
Ferritto, R.3
Kim, S.Y.4
Jeger, P.5
Wipf, P.6
Curran, D.P.7
-
29
-
-
0000992534
-
The Solubility of Fluorocarbons
-
Scott, R. L. The Solubility of Fluorocarbons J. Am. Chem. Soc. 1948, 70, 4090-4093
-
(1948)
J. Am. Chem. Soc.
, vol.70
, pp. 4090-4093
-
-
Scott, R.L.1
-
30
-
-
84859465095
-
Structural Basis for the Enhanced Stability of Highly Fluorinated Proteins
-
Buer, B. C.; Meagher, J. L.; Stuckey, J. A.; Marsh, E. N. G. Structural Basis for the Enhanced Stability of Highly Fluorinated Proteins Proc. Natl. Acad. Sci. U.S.A. 2012, 109, 4810-4815
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 4810-4815
-
-
Buer, B.C.1
Meagher, J.L.2
Stuckey, J.A.3
Marsh, E.N.G.4
-
31
-
-
84867674672
-
Comparison of the Structures and Stabilities of Coiled-Coil Proteins Containing Hexafluoroleucine and t -Butylalanine Provides Insight into the Stabilizing Effects of Highly Fluorinated Amino Acid Side-Chains
-
Buer, B. C.; Meagher, J. L.; Stuckey, J. A.; Marsh, E. N. G. Comparison of the Structures and Stabilities of Coiled-Coil Proteins Containing Hexafluoroleucine and t -Butylalanine Provides Insight into the Stabilizing Effects of Highly Fluorinated Amino Acid Side-Chains Protein Sci. 2012, 21, 1705-1715
-
(2012)
Protein Sci.
, vol.21
, pp. 1705-1715
-
-
Buer, B.C.1
Meagher, J.L.2
Stuckey, J.A.3
Marsh, E.N.G.4
-
32
-
-
0035965730
-
Programmed Self-Sorting of Coiled Coils with Leucine and Hexafluoroleucine Cores
-
Bilgicer, B.; Xing, X. C.; Kumar, K. Programmed Self-Sorting of Coiled Coils with Leucine and Hexafluoroleucine Cores J. Am. Chem. Soc. 2001, 123, 11815-11816
-
(2001)
J. Am. Chem. Soc.
, vol.123
, pp. 11815-11816
-
-
Bilgicer, B.1
Xing, X.C.2
Kumar, K.3
-
33
-
-
0026567907
-
Response of a Protein-Structure to Cavity-Creating Mutations and Its Relation to the Hydrophobic Effect
-
Eriksson, A. E.; Baase, W. A.; Zhang, X. J.; Heinz, D. W.; Blaber, M.; Baldwin, E. P.; Matthews, B. W. Response of a Protein-Structure to Cavity-Creating Mutations and Its Relation to the Hydrophobic Effect Science 1992, 255, 178-183
-
(1992)
Science
, vol.255
, pp. 178-183
-
-
Eriksson, A.E.1
Baase, W.A.2
Zhang, X.J.3
Heinz, D.W.4
Blaber, M.5
Baldwin, E.P.6
Matthews, B.W.7
-
34
-
-
0029002720
-
The Hydrophobic Effect in Protein-Folding
-
Lins, L.; Brasseur, R. The Hydrophobic Effect in Protein-Folding FASEB J. 1995, 9, 535-540
-
(1995)
FASEB J.
, vol.9
, pp. 535-540
-
-
Lins, L.1
Brasseur, R.2
-
35
-
-
4544316921
-
The Polar Hydrophobicity of Fluorinated Compounds
-
Biffinger, J. C.; Kim, H. W.; DiMagno, S. G. The Polar Hydrophobicity of Fluorinated Compounds ChemBioChem. 2004, 5, 622-627
-
(2004)
ChemBioChem.
, vol.5
, pp. 622-627
-
-
Biffinger, J.C.1
Kim, H.W.2
Dimagno, S.G.3
-
37
-
-
0141816814
-
Role of Residual Structure in the Unfolded State of a Thermophilic Protein
-
Robic, S.; Guzman-Casado, M.; Sanchez-Ruiz, J. M.; Marqusee, S. Role of Residual Structure in the Unfolded State of a Thermophilic Protein Proc. Natl. Acad. Sci. U.S.A. 2003, 100, 11345-11349
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 11345-11349
-
-
Robic, S.1
Guzman-Casado, M.2
Sanchez-Ruiz, J.M.3
Marqusee, S.4
-
38
-
-
48849093330
-
Using Fluorous Amino Acids to Modulate the Biological Activity of an Antimicrobial Peptide
-
Gottler, L. M.; Lee, H.-Y.; Shelburne, C. E.; Ramamoorthy, A.; Marsh, E. N. G. Using Fluorous Amino Acids To Modulate the Biological Activity of an Antimicrobial Peptide ChemBioChem. 2008, 9, 370-373
-
(2008)
ChemBioChem.
, vol.9
, pp. 370-373
-
-
Gottler, L.M.1
Lee, H.-Y.2
Shelburne, C.E.3
Ramamoorthy, A.4
Marsh, E.N.G.5
-
39
-
-
50849120027
-
Using Fluorous Amino Acids to Probe the Effects of Changing Hydrophobicity on the Physical and Biological Properties of the Beta-Hairpin Antimicrobial Peptide Protegrin-1
-
Gottler, L. M.; de la Salud Bea, R.; Shelburne, C. E.; Ramamoorthy, A.; Marsh, E. N. Using Fluorous Amino Acids To Probe the Effects of Changing Hydrophobicity on the Physical and Biological Properties of the Beta-Hairpin Antimicrobial Peptide Protegrin-1 Biochemistry 2008, 47, 9243-9250
-
(2008)
Biochemistry
, vol.47
, pp. 9243-9250
-
-
Gottler, L.M.1
De La Salud Bea, R.2
Shelburne, C.E.3
Ramamoorthy, A.4
Marsh, E.N.5
-
40
-
-
0345549549
-
Non-Canonical Amino Acids in Protein Engineering
-
Link, A. J.; Mock, M. L.; Tirrell, D. A. Non-Canonical Amino Acids in Protein Engineering Curr. Opin. Biotechnol. 2003, 14, 603-609
-
(2003)
Curr. Opin. Biotechnol.
, vol.14
, pp. 603-609
-
-
Link, A.J.1
Mock, M.L.2
Tirrell, D.A.3
-
41
-
-
0041520960
-
An Expanded Eukaryotic Genetic Code
-
Chin, J. W.; Cropp, T. A.; Anderson, J. C.; Mukherji, M.; Zhang, Z. W.; Schultz, P. G. An Expanded Eukaryotic Genetic Code Science 2003, 301, 964-967
-
(2003)
Science
, vol.301
, pp. 964-967
-
-
Chin, J.W.1
Cropp, T.A.2
Anderson, J.C.3
Mukherji, M.4
Zhang, Z.W.5
Schultz, P.G.6
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