The kidney tight junction (Review)

International Journal of Molecular Medicine

Volumn 34, Issue 6, 2014, Pages 1451-1457

  Hou, Jianghui ^a  

^a WASHINGTON UNIVERSITY   (United States)

Author keywords

Calcium signaling; Epithelium; Ion channel; Kidney; Scanning ion conductance microscopy; Tight junction

Indexed keywords

CLAUDIN; JUNCTIONAL ADHESION MOLECULE; TIGHT JUNCTION PROTEIN;

GENE MUTATION; HENLE LOOP; HUMAN; HYPERCALCIURIA; HYPERTENSION; HYPOMAGNESEMIA; ION CONDUCTANCE; KIDNEY DISEASE; KIDNEY PROXIMAL TUBULE; KIDNEY STRUCTURE; MEMBRANE PERMEABILITY; NEPHROLITHIASIS; NEPHRON; NONHUMAN; PATHOPHYSIOLOGY; PERMEABILITY BARRIER; PROTEIN FUNCTION; PROTEIN STRUCTURE; REVIEW; TIGHT JUNCTION; TRANSGENIC MOUSE; TRANSPORT KINETICS; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; CYTOLOGY; KIDNEY; METABOLISM; TRANSPORT AT THE CELLULAR LEVEL; X RAY CRYSTALLOGRAPHY;

ANIMALS; BIOLOGICAL TRANSPORT; CLAUDINS; CRYSTALLOGRAPHY, X-RAY; HUMANS; JUNCTIONAL ADHESION MOLECULES; KIDNEY; MODELS, BIOLOGICAL; TIGHT JUNCTION PROTEINS; TIGHT JUNCTIONS;

EID: 84908074776     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2014.1955     Document Type: Review

References (66)

1. Farquhar MG and Palade GE: Junctional complexes in various epithelia. J Cell Biol 17: 375-412, 1963.
2. Goodenough DA and Revel JP: A fine structural analysis of intercellular junctions in the mouse liver. J Cell Biol 45: 272-290, 1970.
3. Stevenson BR and Goodenough DA: Zonulae occludentes in junctional complex-enriched fractions from mouse liver: preliminary morphological and biochemical characterization. J Cell Biol 98: 1209-1221, 1984
4. Hull BE and Staehelin LA: Functional significance of the variations in the geometrical organization of tight junction networks. J Cell Biol 68: 688-704, 1976.
5. Pitelka DR and Taggart BN: Mechanical tension induces lateral movement of intramembrane components of the tight junction: studies on mouse mammary cells in culture. J Cell Biol 96: 606-612, 1983.
6. Smith BE and Braun RE: Germ cell migration across Sertoli cell tight junctions. Science 338: 798-802, 2012.
7. Furuse M, Hirase T, Itoh M., et al: Occludin: a novel integral membrane protein localizing at tight junctions. J Cell Biol 123: 1777-1788, 1993.
8. Ebnet K, Suzuki A, Ohno S., et al: Junctional adhesion molecules (JAMs): more molecules with dual functions? J Cell Sci 117: 19-29, 2004.
9. Furuse M, Fujita K, Hiiragi T., et al: Claudin -1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J Cell Biol 141: 1539-1550, 1998.
10. Saitou M, Furuse M, Sasaki H., et al: Complex phenotype of mice lacking occludin, a component of tight junction strands. Mol Biol Cell 11: 4131-4142, 2000.
11. Du D, Xu F, Yu L., et al: The tight junction protein, occludin, regulates the directional migration of epithelial cells. Dev Cell 18: 52-63, 2010.
12. Bazzoni G: The JAM family of junctional adhesion molecules. Curr Opin Cell Biol 15: 525-530, 2003.
13. Mineta K, Yamamoto Y, Yamazaki Y., et al: Predicted expansion of the claudin multigene family. FEBS Lett 585: 606-612, 2011.
14. Hou J, Rajagopal M and Yu AS: Claudins and the kidney. Annu Rev Physiol 75: 479-501, 2013.
15. Krause G, Winkler L, Mueller S.L., et al: Structure and function of claudins. Biochim Biophys Acta 1778: 631-645, 2008.
16. Colegio OR, Van Itallie C, Rahner C and Anderson JM: Claudin extracellular domains determine paracellular charge selectivity and resistance but not tight junction fibril architecture. Am J Physiol Cell Physiol 284: C1346-C1354, 2003.
17. Hou J, Paul DL and Goodenough DA: Paracellin-1 and the modulation of ion selectivity of tight junctions. J Cell Sci 118: 5109-5118, 2005
18. Van Itallie C., Rahner C and Anderson JM: Regulated expression of claudin-4 decreases paracellular conductance through a selective decrease in sodium permeability. J Clin Iinvest 107: 1319-1327, 2001.
19. Colegio OR, Van Itallie CM, McCrea HJ, Rahner C and Anderson JM: Claudins create charge-selective channels in the paracellular pathway between epithelial cells. Am J Physiol Cell Physiol 283: C142-C147, 2002.
20. Cukierman L, Meertens L, Bertaux C., Kajumo F and Dragic T: Residues in a highly conserved claudin-1 motif are required for hepatitis C virus entry and mediate the formation of cell-cell contacts. J Virol 83: 5477-5484, 2009.
21. Yu AS, Cheng MH, Angelow S, et al: Molecular basis for cation selectivity in claudin-2-based paracellular pores: identification of an electrostatic interaction site. J Gen Physiol 133: 111-127, 2009
22. Piontek J, Winkler L, Wolburg H., et al: Formation of tight junction: determinants of homophilic interaction between classic claudins. FASEB J 22: 146-158, 2008.
23. Fujita K, Katahira J, Horiguchi Y., et al: Clostridium perfringens enterotoxin binds to the second extracellular loop of claudin-3, a tight junction integral membrane protein. FEBS Lett 476: 258-261, 2000.
24. Itoh M, Furuse M, Morita K., et al: Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins. J Cell Biol 147: 1351-1363, 1999
25. Kostrewa D, Brockhaus M, D'Arcy A., et al: X-ray structure of junctional adhesion molecule: structural basis for homophilic adhesion via a novel dimerization motif. EMBO J 20: 4391-4398, 2001.
26. Suzuki H, Nishizawa T, Tani K., et al: Crystal structure of a claudin provides insight into the architecture of tight junctions. Science 344: 304-307, 2014
27. Bagnat M, Cheung ID, Mostov KE and Stainier DY: Genetic control of single lumen formation in the zebrafish gut. Nat Cell Biol 9: 954-960, 2007
28. Suzuki H, Ito Y, Yamazaki Y., et al: The four-transmembrane protein IP39 of Euglena forms strands by a trimeric unit repeat. Nat Commun 4: 1766, 2013.
29. Fromter E: The route of passive ion movement through the epithelium of Necturus gallbladder. J Membr Biol 8: 259-301, 1972.
30. Van Os C.H., de Jong MD and Slegers JF: Dimensions of polar pathways through rabbit gallbladder epithelium. The effect of phloretin on nonelectrolyte permeability. J Membr Biol 15: 363-382, 1974
31. Jones DM, Smallwood RH, Hose D.R., Brown BH and Walker DC: Modelling of epithelial tissue impedance measured using three different designs of probe. Physiol Meas 24: 605-623, 2003.
32. Bendfeldt K, Gitter AH and Fromm M: Trans- and paracellular conductivity of HT-29/B6 cells measured by high-resolution conductance scanning. Ann NY Acad Sci 859: 295-299, 1998.
33. Gitter AH, Bendfeldt K, Schulzke JD and Fromm M: Trans/para-cellular, surface/crypt, and epithelial/subepithelial resistances of mammalian colonic epithelia. Pflugers Arch 439: 477-482, 2000.
34. Gitter AH, Bertog M, Schulzke J and Fromm M: Measurement of paracellular epithelial conductivity by conductance scanning. Pflugers Arch 434: 830-840, 1997
35. Kockerling A, Sorgenfrei D and Fromm M: Electrogenic Na+ absorption of rat distal colon is confined to surface epithelium: a voltage-scanning study. Am J Physiol 264: C1285-C1293, 1993.
36. Hansma PK, Drake B, Marti O., Gould SA and Prater CB: The scanning ion-conductance microscope. Science 243: 641-643, 1989
37. Chen CC, Zhou Y, Morris C.A., Hou J and Baker LA: Scanning ion conductance microscopy measurement of paracellular channel conductance in tight junctions. Anal Chem 85: 3621-3628, 2013.
38. Zhou Y, Chen CC, Weber A.E., Zhou L and Baker LA: Poten-tiometric-scanning ion conductance microscopy. Langmuir 30: 5669-5675, 2014
39. Ohse T, Chang AM, Pippin J.W., et al: A new function for parietal epithelial cells: a second glomerular barrier. Am J Physiol Renal Physiol 297: F1566-F1574, 2009
40. Hasegawa K, Wakino S, Simic P., et al: Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing claudin-1 over-expression in podocytes. Nat Med 19: 1496-1504, 2013.
41. Muto S, Hata M, Taniguchi J., et al: Claudin-2-deficient mice are defective in the leaky and cation-selective paracellular permeability properties of renal proximal tubules. Proc Natl Acad Sci USA 107: 8011-8016, 2010.
42. 2+ channel abundance explains thiazide-induced hypocalciuria and hypomagnesemia. J Clin Invest 115: 1651-1658, 2005
43. Vallon V, Verkman AS and Schnermann J: Luminal hypotonicity in proximal tubules of aquaporin-1-knockout mice. Am J Physiol Renal Physiol 278: F1030-F1033, 2000.
44. Rosenthal R, Milatz S, Krug S.M., et al: Claudin-2, a component of the tight junction, forms a paracellular water channel. J Cell Sci 123: 1913-1921, 2010.
45. 2+ resorption. Science 285: 103-106, 1999.
46. Konrad M, Schaller A, Seelow D., et al: Mutations in the tight-junction gene claudin 19 (CLDN19) are associated with renal magnesium wasting, renal failure, and severe ocular involvement. Am J Hum Genet 79: 949-957, 2006.
47. Hou J, Shan Q, Wang T., et al: Transgenic RNAi depletion of claudin-16 and the renal handling of magnesium. J Biol Chem 282: 17114-17122, 2007.
48. Hou J, Renigunta A, Gomes A.S., et al: Claudin-16 and claudin-19 interaction is required for their assembly into tight junctions and for renal reabsorption of magnesium. Proc Natl Acad Sci USA 106: 15350-15355, 2009.
49. Hou J, Renigunta A, Konrad M., et al: Claudin-16 and claudin-19 interact and form a cation-selective tight junction complex. J Clin Invest 118: 619-628, 2008.
50. Thorleifsson G, Holm H, Edvardsson V., et al: Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density. Nat Genet 41: 926-930, 2009.
51. ++ transport in response to CaSR signalling via a novel microRNA pathway. EMBO J 31: 1999-2012, 2012.
52. ++ metabolism via NFAT-microRNA-based mechanisms. J Am Soc Nephrol 25: 745-760, 2014.
53. Greger R: Cation selectivity of the isolated perfused cortical thick ascending limb of Henle's loop of rabbit kidney. Pflugers Arch 390: 30-37, 1981.
54. Greger R: Ion transport mechanisms in thick ascending limb of Henle's loop of mammalian nephron. Physiol Rev 65: 760-797, 1985.
55. Gong Y, Himmerkus N, Plain A., Bleich M and Hou J: Epigenetic regulation of microRNAs controlling CLDN14 expression as a mechanism for renal calcium handling. J Am Soc Nephrol: Jul 28, 2014 (Epub ahead of print).
56. Loupy A, Ramakrishnan SK, Wootla B, et al: PTH-independent regulation of blood calcium concentration by the calcium-sensing receptor. J Clin Invest 122: 3355-3367, 2012.
57. Hou J: Regulation of paracellular transport in the distal nephron. Curr Opin Nephrol Hypertens 21: 547-551, 2012.
58. Hou J, Renigunta A, Yang J and Waldegger S: Claudin-4 forms paracellular chloride channel in the kidney and requires claudin-8 for tight junction localization. Proc Natl Acad Sci USA 107: 18010-18015, 2010.
59. Fujita H, Hamazaki Y, Noda Y., Oshima M and Minato N: Claudin-4 deficiency results in urothelial hyperplasia and lethal hydronephrosis. PLoS One 7: e52272, 2012.
60. Tatum R, Zhang Y, Salleng K., et al: Renal salt wasting and chronic dehydration in claudin-7-deficient mice. Am J Physiol Renal Physiol 298: F24-F34, 2010.
61. Wilson FH, Disse-Nicodème S, Choate KA, et al: Human hypertension caused by mutations in WNK kinases. Science 293: 1107-1112, 2001.
62. Yamauchi K, Rai T, Kobayashi K., et al: Disease-causing mutant WNK4 increases paracellular chloride permeability and phos-phorylates claudins. Proc Natl Acad Sci USA 101: 4690-4694, 2004.
63. -permeability is regulated by WNK4 kinase: insight into normal physiology and hypertension. Proc Natl Acad Sci USA 101: 14877-14882, 2004.
64. Le Moellic C., Boulkroun S, González-Nunez D, et al: Aldosterone and tight junctions: modulation of claudin-4 phosphorylation in renal collecting duct cells. Am J Physiol Cell Physiol 289: C1513-C1521, 2005.
65. + absorption defends from paracellular back-leakage by claudin-8 upregulation. Biochem Biophys Res Commun 378: 45-50, 2009.
66. Zhou Y, Chen CC, Weber A.E., et al: Potentiometric-scanning ion conductance microscopy for measurement at tight junctions. Tissue Barriers 1: e25585, 2013.