Association between hypermethylation of DNA repetitive elements in white blood cell DNA and pancreatic cancer

Cancer Epidemiology

Volumn 38, Issue 5, 2014, Pages 576-582

  Neale, Rachel E ^a   Clark, Paul J ^a   Fawcett, Jonathan ^b   Fritschi, Lin ^c   Nagler, Belinda N ^a   Risch, Harvey A ^d   Walters, Rhiannon J ^a   Crawford, William J ^a   Webb, Penelope M ^a   Whiteman, David C ^a   Buchanan, Daniel D ^e,f  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c CURTIN UNIVERSITY   (Australia)

^d YALE UNIVERSITY   (United States)

^e UNIVERSITY OF MELBOURNE   (Australia)

^f UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Alu; DNA methylation; LINE 1; Pancreatic cancer; Repetitive DNA elements; Sat2; White blood cell DNA

Indexed keywords

ALCOHOL; REPETITIVE DNA; DNA;

ADULT; AGED; ALCOHOL CONSUMPTION; ARTICLE; BLOOD SAMPLING; BODY MASS; CANCER PATIENT; CANCER RISK; CONTROLLED STUDY; DNA METHYLATION; EDUCATIONAL STATUS; FEMALE; GENETIC ASSOCIATION; HUMAN; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; PANCREAS CANCER; POPULATION BASED CASE CONTROL STUDY; SMOKING; BLOOD; CASE CONTROL STUDY; GENETICS; LONG INTERSPERSED REPEAT; METABOLISM; MIDDLE AGED; PANCREAS TUMOR; PATHOLOGY; POLYMERASE CHAIN REACTION; RISK; VERY ELDERLY;

AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; DNA; DNA METHYLATION; FEMALE; HUMANS; LEUKOCYTES; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; MALE; MIDDLE AGED; PANCREATIC NEOPLASMS; POLYMERASE CHAIN REACTION; RISK;

EID: 84908068697     PISSN: 18777821     EISSN: 1877783X     Source Type: Journal    
DOI: 10.1016/j.canep.2014.08.006     Document Type: Article

References (29)

1. Ferlay J., Shin H., Bray F., Forman D., Mathers C., Parkin D. GLOBOCAN 2008 v2.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 10 [Internet] 2010, International Agency for Research on Cancer, Lyon, France, Available from: http://globocan.iarc.fr [accessed on 19.11.13].
2. Key C. Chapter 7, Cancer of the Pancreas,National Cancer Institute, SEER Survival Monograph.
3. Howlader N., Noone A., Krapcho M., Garshell J., Neyman N., Altekruse S.F., et al. SEER Cancer Statistics Review, 1975-2010 2013, National Cancer Institute, Bethesda, MD, http://seer.cancer.gov/csr/1975_2010/, based on November 2012 SEER data submission, posted to the SEER web site, April 2013.
4. Walters R.J., Williamson E.J., English D.R., Young J.P., Rosty C., Clendenning M., et al. Association between hypermethylation of DNA repetitive elements in white blood cell DNA and early-onset colorectal cancer. Epigenetics 2013, 8:748-755.
5. Moore L.E., Pfeiffer R.M., Poscablo C., Real F.X., Kogevinas M., Silverman D., et al. Genomic DNA hypomethylation as a biomarker for bladder cancer susceptibility in the Spanish Bladder Cancer Study: a case-control study. Lancet Oncol. 2008, 9:359-366.
6. Choi J.Y., James S.R., Link P.A., McCann S.E., Hong C.C., Davis W., et al. Association between global DNA hypomethylation in leukocytes and risk of breast cancer. Carcinogenesis 2009, 30:1889-1897.
7. Liao L.M., Brennan P., van Bemmel D.M., Zaridze D., Matveev V., Janout V., et al. LINE-1 methylation levels in leukocyte DNA and risk of renal cell cancer. PLoS ONE 2011, 6:e27361.
8. Pedersen K.S., Bamlet W.R., Oberg A.L., de Andrade M., Matsumoto M.E., Tang H., et al. Leukocyte DNA methylation signature differentiates pancreatic cancer patients from healthy controls. PLoS ONE 2011, 6:e18223.
9. Dauksa A., Gulbinas A., Barauskas G., Pundzius J., Oldenburg J., El-Maarri O. Whole blood DNA aberrant methylation in pancreatic adenocarcinoma shows association with the course of the disease: a pilot study. PLOS ONE 2012, 7:e37509.
10. Tran B., Whiteman D.C., Webb P.M., Fritschi L., Fawcett J., Risch H.A., et al. Association between ultraviolet radiation, skin sun sensitivity and risk of pancreatic cancer. Cancer Epidemiol 2013, for the Queensland Pancreatic Cancer Study G.
11. Miller S.A., Dykes D.D., Polesky H.F. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988, 16:1215.
12. Weisenberger D.J., Campan M., Long T.I., Kim M., Woods C., Fiala E., et al. Analysis of repetitive element DNA methylation by MethyLight. Nucleic Acids Res 2005, 33:6823-6836.
13. Eads C.A., Danenberg K.D., Kawakami K., Saltz L.B., Blake C., Shibata D., et al. MethyLight: a high-throughput assay to measure DNA methylation. Nucleic Acids Res 2000, 28:E32.
14. Hsiung D.T., Marsit C.J., Houseman E.A., Eddy K., Furniss C.S., McClean M.D., et al. Global DNA methylation level in whole blood as a biomarker in head and neck squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev 2007, 16:108-114.
15. Woo H.D., Kim J. Global DNA hypomethylation in peripheral blood leukocytes as a biomarker for cancer risk: a meta-analysis. PLOS ONE 2012, 7:e34615.
16. Kitkumthorn N., Tuangsintanakul T., Rattanatanyong P., Tiwawech D., Mutirangura A. LINE-1 methylation in the peripheral blood mononuclear cells of cancer patients. Clin Chim Acta 2012, 413:869-874.
17. Nan H., Giovannucci E.L., Wu K., Selhub J., Paul L., Rosner B., et al. Pre-diagnostic leukocyte genomic DNA methylation and the risk of colorectal cancer in women. PLOS ONE 2013, 8:e59455.
18. Tajuddin S.M., Amaral A.F., Fernandez A.F., Rodriguez-Rodero S., Rodriguez R.M., Moore L.E., et al. Genetic and non-genetic predictors of LINE-1 methylation in leukocyte DNA. Environ Health Perspect 2013, 121:650-656.
19. Terry M.B., Delgado-Cruzata L., Vin-Raviv N., Wu H.C., Santella R.M. DNA methylation in white blood cells: association with risk factors in epidemiologic studies. Epigenetics 2011, 6:828-837.
20. Bonassi S., Norppa H., Ceppi M., Stromberg U., Vermeulen R., Znaor A., et al. Chromosomal aberration frequency in lymphocytes predicts the risk of cancer: results from a pooled cohort study of 22358 subjects in 11 countries. Carcinogenesis 2008, 29:1178-1183.
21. Li H., Hilmarsen H.T., Hossain M.B., Bjork J., Hansteen I.L., Albin M., et al. Telomere length and LINE1 methylation is associated with chromosomal aberrations in peripheral blood. Genes Chromosomes Cancer 2013, 52:1-10.
22. Brennan K., Flanagan J.M. Is there a link between genome-wide hypomethylation in blood and cancer risk?. Cancer Prev Res (Phila) 2012, 5:1345-1357.
23. Koestler D.C., Marsit C.J., Christensen B.C., Accomando W., Langevin S.M., Houseman E.A., et al. Peripheral blood immune cell methylation profiles are associated with nonhematopoietic cancers. Cancer Epidemiol. Biomarkers Prev. 2012, 21:1293-1302.
24. Hagner N., Joerger M. Cancer chemotherapy: targeting folic acid synthesis. Cancer Manag Res 2010, 2:293-301.
25. Hannum G., Guinney J., Zhao L., Zhang L., Hughes G., Sadda S., et al. Genome-wide methylation profiles reveal quantitative views of human aging rates. Mol. Cell 2013, 49:359-367.
26. Bocklandt S., Lin W., Sehl M.E., Sanchez F.J., Sinsheimer J.S., Horvath S., et al. Epigenetic predictor of age. PLoS One 2011, 6:e14821.
27. Koch C.M., Wagner W. Epigenetic-aging-signature to determine age in different tissues. Aging (Albany NY) 2011, 3:1018-1027.
28. Reinius L.E., Acevedo N., Joerink M., Pershagen G., Dahlen S.E., Greco D., et al. Differential DNA methylation in purified human blood cells: implications for cell lineage and studies on disease susceptibility. PLoS One 2012, 7:e41361.
29. Wu H.C., Delgado-Cruzata L., Flom J.D., Kappil M., Ferris J.S., Liao Y., et al. Global methylation profiles in DNA from different blood cell types. Epigenetics 2011, 6:76-85.