Pre-Diagnostic Leukocyte Genomic DNA Methylation and the Risk of Colorectal Cancer in Women

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Nan, Hongmei ^a,b   Giovannucci, Edward L ^b,d   Wu, Kana ^d   Selhub, Jacob ^e   Paul, Ligi ^e   Rosner, Bernard ^b,d   Fuchs, Charles S ^b,c   Cho, Eunyoung ^b  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c DANA FARBER CANCER INSTITUTE   (United States)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^e TUFTS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA;

ADULT; AGED; ARTICLE; BLOOD ANALYSIS; CANCER RISK; CARBON METABOLISM; CASE CONTROL STUDY; COHORT ANALYSIS; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA METHYLATION; FEMALE; GENE INTERACTION; HUMAN; LEUKOCYTE; LIQUID CHROMATOGRAPHY; MAJOR CLINICAL STUDY; ONE CARBON METABOLISM; POPULATION RISK; RISK FACTOR; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY;

ADENOCARCINOMA; ADULT; CASE-CONTROL STUDIES; COLORECTAL NEOPLASMS; CYSTEINE; DNA METHYLATION; DNA, NEOPLASM; FEMALE; HEALTH SURVEYS; HOMOCYSTEINE; HUMANS; LEUKOCYTES, MONONUCLEAR; LOGISTIC MODELS; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MIDDLE AGED; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; PYRIDOXAL PHOSPHATE; RISK FACTORS;

EID: 84875674381     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0059455     Document Type: Article

References (42)

1. Mason JB, (2003) Biomarkers of nutrient exposure and status in one-carbon (methyl) metabolism. J Nutr 133Suppl 3: 941S-947S.
2. Choi SW, Mason JB, (2002) Folate status: effects on pathways of colorectal carcinogenesis. J Nutr 132: 2413S-2418S.
3. Lim U, Flood A, Choi SW, Albanes D, Cross AJ, et al. (2008) Genomic methylation of leukocyte DNA in relation to colorectal adenoma among asymptomatic women. Gastroenterology 134: 47-55.
4. Colditz GA, Hankinson SE, (2005) The Nurses' Health Study: lifestyle and health among women. Nat Rev Cancer 5: 388-396.
5. Smith-Warner SA, Spiegelman D, Ritz J, Albanes D, Beeson WL, et al. (2006) Methods for pooling results of epidemiologic studies: the Pooling Project of Prospective Studies of Diet and Cancer. Am J Epidemiol 163: 1053-1064.
6. Stampfer MJ, Willett WC, Speizer FE, Dysert DC, Lipnick R, et al. (1984) Test of the National Death Index. Am J Epidemiol 119: 837-839.
7. U.S. Department of Agriculture, Agriculture Research Service (1999) USDA Nutrient Data Laboratory. USDA Nutrient Database for Standard Reference, release 13. Washington, DC: Department of Agriculture.
8. Willett W, Stamper M (1998) Implications of total energy intake for epidemiologic analysis. In: Willett W, ed. Nutritional Epidemiology. 2nd ed. New York, HY: Oxford University Press 273-301.
9. Wei EK, Giovannucci E, Selhub J, Fuchs CS, Hankinson SE, et al. (2005) Plasma vitamin B6 and the risk of colorectal cancer and adenoma in women. J Natl Cancer Inst 97: 684-692.
10. Shin YS, Rasshofer R, Friedrich B, Endres W, (1983) Pyridoxal-5′-phosphate determination by a sensitive micromethod in human blood, urine and tissues; its relation to cystathioninuria in neuroblastoma and biliary atresia. Clin Chim Acta 127: 77-85.
11. Araki A, Sako Y, (1987) Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection. J Chromatogr 422: 43-52.
12. Zhang SM, Willett WC, Selhub J, Hunter DJ, Giovannucci EL, et al. (2003) Plasma folate, vitamin B6, vitamin B12, homocysteine, and risk of breast cancer. J Natl Cancer Inst 95: 373-380.
13. Friso S, Girelli D, Trabetti E, Olivieri O, Guarini P, et al. (2005) The MTHFR 1298A>C polymorphism and genomic DNA methylation in human lymphocytes. Cancer Epidemiol Biomarkers Prev 14: 938-943.
14. Levine AJ, Siegmund KD, Ervin CM, Diep A, Lee ER, et al. (2000) The methylenetetrahydrofolate reductase 677C->T polymorphism and distal colorectal adenoma risk. Cancer Epidemiol Biomarkers Prev 9: 657-663.
15. van der Put NM, Gabreels F, Stevens EM, Smeitink JA, Trijbels FJ, et al. (1998) A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects? Am J Hum Genet 62: 1044-1051.
16. Koushik A, Kraft P, Fuchs CS, Hankinson SE, Willett WC, et al. (2006) Nonsynonymous polymorphisms in genes in the one-carbon metabolism pathway and associations with colorectal cancer. Cancer Epidemiol Biomarkers Prev 15: 2408-2417.
17. Song L, James SR, Kazim L, Karpf AR, (2005) Specific method for the determination of genomic DNA methylation by liquid chromatography-electrospray ionization tandem mass spectrometry. Analytical chemistry 77: 504-510.
18. Ogino S, Nosho K, Kirkner GJ, Kawasaki T, Chan AT, et al. (2008) A cohort study of tumoral LINE-1 hypomethylation and prognosis in colon cancer. Journal of the National Cancer Institute 100: 1734-1738.
19. Schernhammer ES, Giovannucci E, Kawasaki T, Rosner B, Fuchs CS, et al. (2010) Dietary folate, alcohol and B vitamins in relation to LINE-1 hypomethylation in colon cancer. Gut 59: 794-799.
20. Kim YI, (2004) Folate and DNA methylation: a mechanistic link between folate deficiency and colorectal cancer? Cancer Epidemiol Biomarkers Prev 13: 511-519.
21. Agrawal A, Murphy RF, Agrawal DK, (2007) DNA methylation in breast and colorectal cancers. Mod Pathol 20: 711-721.
22. Laird PW, (2003) The power and the promise of DNA methylation markers. Nat Rev Cancer 3: 253-266.
23. Choi SW, Stickel F, Baik HW, Kim YI, Seitz HK, et al. (1999) Chronic alcohol consumption induces genomic but not p53-specific DNA hypomethylation in rat colon. J Nutr 129: 1945-1950.
24. Eden A, Gaudet F, Waghmare A, Jaenisch R, (2003) Chromosomal instability and tumors promoted by DNA hypomethylation. Science 300: 455.
25. Pufulete M, Al-Ghnaniem R, Rennie JA, Appleby P, Harris N, et al. (2005) Influence of folate status on genomic DNA methylation in colonic mucosa of subjects without colorectal adenoma or cancer. Br J Cancer 92: 838-842.
26. Stern LL, Mason JB, Selhub J, Choi SW, (2000) Genomic DNA hypomethylation, a characteristic of most cancers, is present in peripheral leukocytes of individuals who are homozygous for the C677T polymorphism in the methylenetetrahydrofolate reductase gene. Cancer Epidemiol Biomarkers Prev 9: 849-853.
27. Pufulete M, Al-Ghnaniem R, Leather AJ, Appleby P, Gout S, et al. (2003) Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: a case control study. Gastroenterology 124: 1240-1248.
28. Huang WY, Su LJ, Hayes RB, Moore LE, Katki HA, et al. (2012) Prospective Study of Genomic Hypomethylation of Leukocyte DNA and Colorectal Cancer Risk. Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
29. de Vogel S, Bongaerts BW, Wouters KA, Kester AD, Schouten LJ, et al. (2008) Associations of dietary methyl donor intake with MLH1 promoter hypermethylation and related molecular phenotypes in sporadic colorectal cancer. Carcinogenesis 29: 1765-1773.
30. Kim MS, Lebron C, Nagpal JK, Chae YK, Chang X, et al. (2008) Methylation of the DFNA5 increases risk of lymph node metastasis in human breast cancer. Biochem Biophys Res Commun 370: 38-43.
31. van Engeland M, Derks S, Smits KM, Meijer GA, Herman JG, (2011) Colorectal cancer epigenetics: complex simplicity. J Clin Oncol 29: 1382-1391.
32. Choi SW, Mason JB, (2000) Folate and carcinogenesis: an integrated scheme. J Nutr 130: 129-132.
33. Giovannucci E, (2004) Alcohol, one-carbon metabolism, and colorectal cancer: recent insights from molecular studies. J Nutr 134: 2475S-2481S.
34. Mason JB, Choi SW, (2005) Effects of alcohol on folate metabolism: implications for carcinogenesis. Alcohol 35: 235-241.
35. Lucock M, Yates Z, (2005) Folic acid- vitamin and panacea or genetic time bomb? Nat Rev Genet 6: 235-240.
36. Kim YI, (1999) Folate and carcinogenesis: evidence, mechanisms, and implications. J Nutr Biochem 10: 66-88.
37. Rampersaud GC, Kauwell GP, Hutson AD, Cerda JJ, Bailey LB, (2000) Genomic DNA methylation decreases in response to moderate folate depletion in elderly women. Am J Clin Nutr 72: 998-1003.
38. Friso S, Choi SW, (2002) Gene-nutrient interactions and DNA methylation. J Nutr 132: 2382S-2387S.
39. Friso S, Choi SW, Girelli D, Mason JB, Dolnikowski GG, et al. (2002) A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status. Proc Natl Acad Sci U S A 99: 5606-5611.
40. Kim YI, (2007) Folate and colorectal cancer: an evidence-based critical review. Mol Nutr Food Res 51: 267-292.
41. van Bemmel D, Lenz P, Liao LM, Baris D, Sternberg LR, et al. (2012) Correlation of LINE-1 methylation levels in patient-matched buffy coat, serum, buccal cell, and bladder tumor tissue DNA samples. Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 21: 1143-1148.
42. Breslow NE, Day NE (1987) Statistical methods in cancer research. IARC Workshop 25-27 May 1983. IARC Sci Publ: 1-406.