Prophylactic effect of baicalein against renal dysfunction in type 2 diabetic rats

Biochimie

Volumn 106, Issue , 2014, Pages 101-110

  Ahad, Amjid ^a   Mujeeb, Mohd ^b   Ahsan, Haseeb ^c   Siddiqui, Waseem Ahmad ^a  

^a HAMDARD UNIVERSITY   (India)

^b HAMDARD UNIVERSITY   (India)

^c JAMIA MILLIA ISLAMIA CENTRAL UNIVERSITY   (India)

Author keywords

Baicalein; Diabetic nephropathy; Insulin resistance; Oxidative stress; Renal function

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BAICALEIN; CATALASE; GLUCOSE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HEMOGLOBIN A1C; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; NITRIC OXIDE; ROSIGLITAZONE; STREPTOZOCIN; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIDIABETIC AGENT; ANTIOXIDANT; CYTOKINE; FLAVANONE DERIVATIVE; GLUCOSE BLOOD LEVEL;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY WEIGHT; COMA; CONTROLLED STUDY; CONVULSION; CREATININE CLEARANCE; DIABETIC NEPHROPATHY; DIARRHEA; DRUG EFFICACY; FOOD INTAKE; GLUCOSE BLOOD LEVEL; HEMOGLOBIN BLOOD LEVEL; HISTOPATHOLOGY; KIDNEY FUNCTION; KIDNEY PARENCHYMA; LETHARGY; LIVER FUNCTION; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN BLOOD LEVEL; PROTEIN URINE LEVEL; RAT; RENAL PROTECTION; SALIVATION DISORDER; SLEEP DISORDER; THERAPY EFFECT; TREMOR; WISTAR RAT; ANIMAL; BLOOD; CHEMICALLY INDUCED; COMPLICATION; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; DRUG EFFECTS; EATING; KIDNEY; LIPID DIET; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; TREATMENT OUTCOME; WESTERN BLOTTING;

ALANINE TRANSAMINASE; ANIMALS; ANTIOXIDANTS; ASPARTATE AMINOTRANSFERASES; BLOOD GLUCOSE; BLOTTING, WESTERN; BODY WEIGHT; CYTOKINES; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; DIET, HIGH-FAT; EATING; FLAVANONES; HYPOGLYCEMIC AGENTS; KIDNEY; MALE; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; RATS, WISTAR; STREPTOZOCIN; THIAZOLIDINEDIONES; TRANSFORMING GROWTH FACTOR BETA1; TREATMENT OUTCOME;

EID: 84908046289     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2014.08.006     Document Type: Article

References (55)

1. E. Ritz, C. Keller, K. Bergis, and K. Strojek Pathogenesis and course of renal disease in IDDM/NIDDM: differences and similarities Am. J. Hypertens. 10 1997 202S 207S
2. J.L. Gross, M.J. de Azevedo, S.P. Silveiro, L.H. Canani, M.L. Caramori, and T. Zelmanovitz Diabetic nephropathy: diagnosis, prevention, and treatment Diabetes Care 28 2005 164 176
3. C. Mora, and J.F. Navarro Inflammation and diabetic nephropathy Curr. Diabetes Rep. 6 2006 463 468
4. D. Nguyen, F. Ping, W. Mu, P. Hill, R.C. Atkins, and S.J. Chadban Macrophage accumulation in human progressive diabetic nephropathy Nephrol. Carlt. 11 2006 226 231
5. F.Y. Chow, D.J. Nikolic-Paterson, R.C. Atkins, and G.H. Tesch Macrophages in streptozotocin-induced diabetic nephropathy: potential role in renal fibrosis Nephrol. Dial. Transpl. 19 2004 2987 2996
6. H. Ha, M.R. Yu, Y.J. Choi, M. Kitamura, and H.B. Lee Role of high glucose-induced nuclear factor-kappaB activation in monocyte chemoattractant protein-1 expression by mesangial cells J. Am. Soc. Nephrol. 13 2002 894 902
7. S. Pillarisetti, and U. Saxena Role of oxidative stress and inflammation in the origin of Type 2 diabetes - a paradigm shift Exp. Opin. Ther. Target 8 2004 401 408
8. B. Yang, A. Hodgkinson, P.J. Oates, B.A. Millward, and A.G. Demaine High glucose induction of DNA-binding activity of the transcription factor NFκB in patients with diabetic nephropathy Biochim. Biophys. Acta Mol. Basis Dis. 1782 2008 295 302
9. C.W. Park, J.H. Kim, J.H. Lee, Y.S. Kim, H.J. Ahn, Y.S. Shin, S.Y. Kim, E.J. Choi, Y.S. Chang, and B.K. Bang High glucose-induced intercellular adhesion molecule-1 (ICAM-1) expression through an osmotic effect in rat mesangial cells is PKC-NF-kappa B-dependent Diabetologia 43 2000 1544 1553
10. L. Dey, A.S. Attele, and C.S. Yuan Alternative therapies for type 2 diabetes Altern. Med. Rev. 7 2002 45 58
11. M. Zamboni, V. Di Francesco, U. Garbin, A. Fratta Pasini, G. Mazzali, C. Stranieri, E. Zoico, F. Fantin, O. Bosello, and L. Cominacini Adiponectin gene expression and adipocyte NF-kappaB transcriptional activity in elderly overweight and obese women: inter-relationships with fat distribution, hs-CRP, leptin and insulin resistance Int. J. Obes. 31 2007 1104 1109
12. C.F. Skibola, and M.T. Smith Potential health impacts of excessive flavonoid intake Free Radic. Biol. Med. 29 2000 375 383
13. Z. Gao, K. Huang, X. Yang, and H. Xu Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi Biochim. Biophys. Acta 1472 1999 643 650
14. Y.C. Shen, W.F. Chiou, Y.C. Chou, and C.F. Chen Mechanisms in mediating the anti-inflammatory effects of baicalin and baicalein in human leukocytes Eur. J. Pharmacol. 465 2003 171 181
15. C.C. Lin, and D.E. Shieh The anti-inflammatory activity of Scutellaria rivularis extracts and its active components, baicalin, baicalein and wogonin Am. J. Chin. Med. 24 1996 31 36
16. P. Pu, X.A. Wang, M. Salim, L.H. Zhu, L. Wang, K.J. Chen, J.F. Xiao, W. Deng, H.W. Shi, H. Jiang, and H.L. Li Baicalein, a natural product, selectively activating AMPKalpha(2) and ameliorates metabolic disorder in diet-induced mice Mol. Cell. Endocrinol. 362 2012 128 138
17. L. Cui, X. Zhang, R. Yang, L. Liu, L. Wang, M. Li, and W. Du Baicalein is neuroprotective in rat MCAO model: role of 12/15-lipoxygenase, mitogen-activated protein kinase and cytosolic phospholipase A2 Pharmacol. Biochem. Behav. 96 2010 469 475
18. C. Ghai A Text Book of Practical Physiology 1990 Jaypee Brothers (P) Ltd. India 119 120
19. M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem. 72 1976 248 254
20. H. Ohkawa, N. Ohishi, and K. Yagi Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction Anal. Biochem. 95 1979 351 358
21. S. Marklund, and G. Marklund Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase Eur. J. Biochem. 47 1974 469 474
22. A. Claiborne Catalase activity R.A. Greenwald, CRC Handbook of Methods in Oxygen Radical Research 1985 CRC Press Boca Raton 283 284
23. R.S. Danda, N.M. Habiba, H. Rincon-Choles, B.K. Bhandari, J.L. Barnes, H.E. Abboud, and P.E. Pergola Kidney involvement in a nongenetic rat model of type 2 diabetes Kidney Int. 68 2005 2562 2571
24. L. Arreola-Mendoza, J.L. Reyes, E. Melendez, D. Martin, M.C. Namorado, E. Sanchez, and L.M. Del Razo Alpha-tocopherol protects against the renal damage caused by potassium dichromate Toxicology 218 2006 237 246
25. D.J. Jollow, J.R. Mitchell, N. Zampaglione, and J.R. Gillette Bromobenzene-induced liver necrosis. Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite Pharmacology 11 1974 151 169
26. J. Mohandas, J.J. Marshall, G.G. Duggin, J.S. Horvath, and D.J. Tiller Differential distribution of glutathione and glutathione-related enzymes in rabbit kidney. Possible implications in analgesic nephropathy Biochem. Pharmacol. 33 1984 1801 1807
27. I. Carlberg, and B. Mannervik Purification and characterization of the flavoenzyme glutathione reductase from rat liver J. Biol. Chem. 250 1975 5475 5480
28. S. Siddiqui, H. Ahsan, M.R. Khan, and W.A. Siddiqui Protective effects of tocotrienols against lipid-induced nephropathy in experimental type-2 diabetic rats by modulation in TGF-β expression Toxicol. Appl. Pharmacol. 273 2013 314 324
29. A. Ahad, A.A. Ganai, M. Mujeeb, and W.A. Siddiqui Ellagic acid, an NF-κB inhibitor, ameliorates renal function in experimental diabetic nephropathy Chem. Biol. Interact. 219 2014 64 75
30. T.M. Coimbra, U. Janssen, H.J. Grone, T. Ostendorf, U. Kunter, H. Schmidt, G. Brabant, and J. Floege Early events leading to renal injury in obese Zucker (fatty) rats with type II diabetes Kidney Int. 57 2000 167 182
31. A. Kuhad, and K. Chopra Attenuation of diabetic nephropathy by tocotrienol: involvement of NFkB signaling pathway Life Sci. 84 2009 296 301
32. T. Nishioka, J. Kawabata, and Y. Aoyama Baicalein, an alpha-glucosidase inhibitor from Scutellaria baicalensis J. Nat. Prod. 61 1998 1413 1415
33. R. Stavniichuk, V.R. Drel, H. Shevalye, Y. Maksimchyk, T.M. Kuchmerovska, J.L. Nadler, and I.G. Obrosova Baicalein alleviates diabetic peripheral neuropathy through inhibition of oxidative-nitrosative stress and p38 MAPK activation Exp. Neurol. 230 2011 106 113
34. L. Raij, and C. Baylis Glomerular actions of nitric oxide Kidney Int. 48 1995 20 32
35. S. Keynan, B. Hirshberg, N. Levin-Iaina, I.D. Wexler, R. Dahan, E. Reinhartz, H. Ovadia, Y. Wollman, T. Chernihovskey, A. Iaina, and I. Raz Renal nitric oxide production during the early phase of experimental diabetes mellitus Kidney Int. 58 2000 740 747
36. A. Maree, G. Peer, A. Iaina, M. Blum, Y. Wollman, T. Csernihovsky, D.S. Silverberg, and S. Cabili Nitric oxide in streptozotocin-induced diabetes mellitus in rats Clin. Sci. Lond. 90 1996 379 384
37. P.A. Craven, M.F. Melhem, and F.R. DeRubertis Thromboxane in the pathogenesis of glomerular injury in diabetes Kidney Int. 42 1992 937 946
38. R.J. Falk, J.I. Scheinman, S.M. Mauer, and A.F. Michael Polyantigenic expansion of basement membrane constituents in diabetic nephropathy Diabetes 32 Suppl. 2 1983 34 39
39. A. Nerlich, and E. Schleicher Immunohistochemical localization of extracellular matrix components in human diabetic glomerular lesions Am. J. Pathol. 139 1991 889 899
40. G. Wolf, and F.N. Ziyadeh Molecular mechanisms of diabetic renal hypertrophy Kidney Int. 56 1999 393 405
41. J.E. Kim, M.H. Lee, D.H. Nam, H.K. Song, Y.S. Kang, J.E. Lee, H.W. Kim, J.J. Cha, Y.Y. Hyun, S.Y. Han, K.H. Han, J.Y. Han, and D.R. Cha Celastrol, an NF-kappaB inhibitor, improves insulin resistance and attenuates renal injury in db/db mice PloS One 8 2013 e62068
42. D. Macconi, M. Abbate, M. Morigi, S. Angioletti, M. Mister, S. Buelli, M. Bonomelli, P. Mundel, K. Endlich, A. Remuzzi, and G. Remuzzi Permselective dysfunction of podocyte-podocyte contact upon angiotensin II unravels the molecular target for renoprotective intervention Am. J. Pathol. 168 2006 1073 1085
43. P. Alonso-Magdalena, A.B. Ropero, M. Garcia-Arevalo, S. Soriano, I. Quesada, S.J. Muhammed, A. Salehi, J.A. Gustafsson, and A. Nadal Antidiabetic actions of an estrogen receptor β selective agonist Diabetes 62 6 2013 2015 2025
44. E.T. McCarthy, R. Sharma, M. Sharma, J.Z. Li, X.L. Ge, K.N. Dileepan, and V.J. Savin TNF-alpha increases albumin permeability of isolated rat glomeruli through the generation of superoxide J. Am. Soc. Nephrol. 9 1998 433 438
45. L. Baud, and R. Ardaillou Tumor necrosis factor in renal injury Miner. Electrol. Metabol. 21 1995 336 341
46. H. Trachtman, S. Futterweit, E. Pine, J. Mann, and E. Valderrama Chronic diabetic nephropathy: role of inducible nitric oxide synthase Pediatr. Nephrol. 17 2002 20 29
47. B.B. Hoffman, K. Sharma, Y. Zhu, and F.N. Ziyadeh Transcriptional activation of transforming growth factor-beta1 in mesangial cell culture by high glucose concentration Kidney Int. 54 1998 1107 1116
48. Y.J. Surh, K.S. Chun, H.H. Cha, S.S. Han, Y.S. Keum, K.K. Park, and S.S. Lee Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation Mutat. Res. 480-481 2001 243 268
49. J. Wada, and H. Makino Inflammation and the pathogenesis of diabetic nephropathy Clin. Sci. Lond. 124 2013 139 152
50. P. Paueksakon, M.P. Revelo, L.J. Ma, C. Marcantoni, and A.B. Fogo Microangiopathic injury and augmented PAI-1 in human diabetic nephropathy Kidney Int. 61 2002 2142 2148
51. H. Abrahamian, G. Endler, M. Exner, H. Mauler, M. Raith, L. Endler, H. Rumpold, M. Gerdov, C. Mannhalter, R. Prager, K. Irsigler, and O.F. Wagner Association of low-grade inflammation with nephropathy in type 2 diabetic patients: role of elevated CRP-levels and 2 different gene-polymorphisms of proinflammatory cytokines Exp. Clin. Endocrinol. Diabetes 115 2007 38 41
52. G. Hasegawa, K. Nakano, and M. Kondo Role of TNF and IL-1 in the development of diabetic nephropathy Nefrologia 5 1995 1 4
53. T. Nakamura, M. Fukui, I. Ebihara, S. Osada, I. Nagaoka, Y. Tomino, and H. Koide mRNA expression of growth factors in glomeruli from diabetic rats Diabetes 42 1993 450 456
54. N. Kashihara, Y. Haruna, V.K. Kondeti, and Y.S. Kanwar Oxidative stress in diabetic nephropathy Curr. Med. Chem. 17 2010 4256 4269
55. Z. Gao, K. Huang, and H. Xu Protective effects of flavonoids in the roots of Scutellaria baicalensis Georgi against hydrogen peroxide-induced oxidative stress in HS-SY5Y cells Pharmacol. Res. 43 2001 173 178