Repair-related activation of hedgehog signaling in stromal cells promotes intrahepatic hypothyroidism

Endocrinology (United States)

Volumn 155, Issue 11, 2014, Pages 4591-4601

  Bohinc, Brittany N ^a   Michelotti, Gregory ^b   Xie, Guanhua ^b   Pang, Herbert ^c,f   Suzuki, Ayako ^b,e   Guy, Cynthia D ^c   Piercy, Dawn ^a   Kruger, Leandi ^b   Swiderska Syn, Marzena ^b   Machado, Mariana ^b   Pereira, Thiago ^b   Zavacki, Ann Marie ^d   Abdelmalek, Manal ^b   Diehl, Anna Mae ^b  

^a DUKE UNIVERSITY   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e Div of Gastroenterol and Hepatol   (United States)

^f UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

3,3',5' TRIIODOTHYRONINE; LIOTHYRONINE; SONIC HEDGEHOG PROTEIN; THYROID HORMONE; THYROXINE 1 DEIODINASE; THYROXINE 3 DEIODINASE; THYROXINE DEIODINASE; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ARTICLE; BODY MASS; CELL DIFFERENTIATION; CHRONIC LIVER DISEASE; CLINICAL ARTICLE; FREE LIOTHYRONINE INDEX; FREE THYROXINE INDEX; HUMAN; HUMAN TISSUE; HYPOTHYROIDISM; INTRACELLULAR SIGNALING; INTRAHEPATIC HYPOTHYROIDISM; LIOTHYRONINE BLOOD LEVEL; LIQUID CHROMATOGRAPHY; LIVER BIOPSY; LIVER CELL; LIVER FIBROSIS; LIVER INJURY; MALE; MOUSE; MYOFIBROBLAST; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; STELLATE CELL; STROMA CELL; TANDEM MASS SPECTROMETRY; THYROXINE BLOOD LEVEL; UPREGULATION; ANIMAL; C57BL MOUSE; CASE CONTROL STUDY; CELL CULTURE; GENE EXPRESSION REGULATION; GENETICS; LIVER; LIVER REGENERATION; METABOLISM; NONALCOHOLIC FATTY LIVER; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; TRANSGENIC MOUSE; WOUND HEALING;

ANIMALS; CASE-CONTROL STUDIES; CELLS, CULTURED; GENE EXPRESSION REGULATION; HEDGEHOG PROTEINS; HUMANS; HYPOTHYROIDISM; LIVER; LIVER REGENERATION; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NON-ALCOHOLIC FATTY LIVER DISEASE; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STROMAL CELLS; THYROID HORMONES; WOUND HEALING;

EID: 84908042914     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2014-1302     Document Type: Article

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