β-catenin regulates deiodinase levels and thyroid hormone signaling in colon cancer cells

Gastroenterology

Volumn 143, Issue 4, 2012, Pages 1037-1047

  Dentice, Monica ^a   Luongo, Cristina ^a   Ambrosio, Raffaele ^b   Sibilio, Annarita ^a   Casillo, Antonella ^a   Iaccarino, Antonino ^a   Troncone, Giancarlo ^a   Fenzi, Gianfranco ^a   Larsen, P Reed ^c   Salvatore, Domenico ^a,d  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b IRCCS SDN   (Italy)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d CEINGE BIOTECNOLOGIE AVANZATE   (Italy)

Author keywords

Colorectal Cancer; Hypothalamus; Intestinal Epithelium; Thyroid Receptor

Indexed keywords

BETA CATENIN; ENZYME; LIOTHYRONINE; T CELL FACTOR PROTEIN; THYROID HORMONE; TYPE 3 DEIODINASE; UNCLASSIFIED DRUG; UVOMORULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CARCINOGENESIS; CELL CULTURE; CELL DIFFERENTIATION; CELL MEMBRANE; CELL PROLIFERATION; COLON ADENOMA; COLON CARCINOMA; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME BLOOD LEVEL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT;

EID: 84866721523     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2012.06.042     Document Type: Article

References (34)

1. A.C. Bianco, D. Salvatore, B. Gereben Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases Endocr Rev 23 2002 38 89
2. V.A. Galton The roles of the iodothyronine deiodinases in mammalian development Thyroid 15 2005 823 834
3. M. Dentice, A. Marsili, R. Ambrosio et al. The FoxO3/type 2 deiodinase pathway is required for normal mouse myogenesis and muscle regeneration J Clin Invest 120 2010 4021 4030
4. M. Dentice, D. Salvatore Deiodinases: the balance of thyroid hormone Local impact of thyroid hormone inactivation J Endocrinol 209 2011 273 282
5. M.H. Kester, G.G. Kuiper, R. Versteeg Regulation of type III iodothyronine deiodinase expression in human cell lines Endocrinology 147 2006 5845 5854
6. A. Klaus, W. Birchmeier Wnt signalling and its impact on development and cancer Nat Rev Cancer 8 2008 387 398
7. R. Kemler From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion Trends Genet 9 1993 317 321
8. -/- colon carcinoma Science 275 1997 1784 1787
9. T.S. Stappenbeck, M.H. Wong, J.R. Saam Notes from some crypt watchers: regulation of renewal in the mouse intestinal epithelium Curr Opin Cell Biol 10 1998 702 709
10. K.M. Cadigan, R. Nusse Wnt signaling: a common theme in animal development Genes Dev 11 1997 3286 3305
11. Y.B. Shi, J. Wong, M. Puzianowska-Kuznicka, M.A. Stolow Tadpole competence and tissue-specific temporal regulation of amphibian metamorphosis: roles of thyroid hormone and its receptors Bioessays 18 1996 391 399
12. M. Sirakov, M. Plateroti The thyroid hormones and their nuclear receptors in the gut: from developmental biology to cancer Biochim Biophys Acta 1812 2011 938 946
13. E. Kress, A. Rezza, J. Nadjar The frizzled-related sFRP2 gene is a target of thyroid hormone receptor alpha1 and activates β-catenin signaling in mouse intestine J Biol Chem 284 2009 1234 1241
14. E. Saggiorato, R. De Pompa, M. Volante Characterization of thyroid "follicular neoplasms" in fine-needle aspiration cytological specimens using a panel of immunohistochemical markers: a proposal for clinical application Endocr Relat Cancer 12 2005 305 317
15. S.A. Huang, D.M. Dorfman, D.R. Genest Type 3 iodothyronine deiodinase is highly expressed in the human uteroplacental unit and in fetal epithelium J Clin Endocrinol Metab 88 2003 1384 1388
16. M. Dentice, C. Luongo, A. Elefante Transcription factor Nkx-2.5 induces sodium/iodide symporter gene expression and participates in retinoic acid- and lactation-induced transcription in mammary cells Mol Cell Biol 24 2004 7863 7877
17. M. Dentice, C. Luongo, A. Elefante Pendrin is a novel in vivo downstream target gene of the TTF-1/Nkx-2.1 homeodomain transcription factor in differentiated thyroid cells Mol Cell Biol 25 2005 10171 10182
18. M. Dentice, A. Bandyopadhyay, B. Gereben The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate Nat Cell Biol 7 2005 698 705
19. M. Dentice, C. Luongo, S. Huang Sonic Hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes Proc Natl Acad Sci U S A 104 2007 14466 144671
20. J.M. Mariadason, M. Bordonaro, F. Aslam Down-regulation of β-catenin TCF signaling is linked to colonic epithelial cell differentiation Cancer Res 61 2001 3465 3471
21. M. van de Wetering, E. Sancho, C. Verweij The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells Cell 111 2002 241 250
22. A.R. Clarke Wnt signalling in the mouse intestine Oncogene 25 2006 7512 7521
23. M. Dentice, R. Ambrosio, D. Salvatore Role of type 3 deiodinase in cancer Expert Opin Ther Targets 13 2009 1363 1373
24. H. Clevers Wnt/β-catenin signaling in development and disease Cell 127 2006 469 480
25. D.D. Brown The role of deiodinases in amphibian metamorphosis Thyroid 15 2005 815 821
26. M. Dentice Hedgehog-mediated regulation of thyroid hormone action through iodothyronine deiodinases Expert Opin Ther Targets 15 2011 493 504
27. M. Sirakov, M. Plateroti The thyroid hormones and their nuclear receptors in the gut: from developmental biology to cancer Biochim Biophys Acta 1812 2011 938 946
28. W.C. Watson, J.F. Tuckerman Effect of thyroid status on intestinal alkaline phosphatase levels in the rat Endocrinology 88 1971 1524 1527
29. M. Plateroti, E. Kress, J.I. Mori, J. Samarut Thyroid hormone receptor alpha1 directly controls transcription of the β-catenin gene in intestinal epithelial cells Mol Cell Biol 26 2006 3204 3214
30. C. Jumarie, F.E. Herring-Gillam, J.F. Beaulieu Triiodothyronine stimulates the expression of sucrase-isomaltase in Caco-2 cells cultured in serum-free medium Exp Cell Res 222 1996 319 325
31. H. Natsume, S. Sasaki, M. Kitagawa β-Catenin/Tcf-1-mediated transactivation of cyclin D1 promoter is negatively regulated by thyroid hormone Biochem Biophys Res Commun 309 2003 408 413
32. Y. Kang, J. Massague Epithelial-mesenchymal transitions: twist in development and metastasis Cell 118 2004 277 279
33. C.J. Guigon, L. Zhao, C. Lu Regulation of β-catenin by a novel nongenomic action of thyroid hormone beta receptor Mol Cell Biol 28 2008 4598 4608
34. C.J. Guigon, D.W. Kim, X. Zhu et al. Tumor suppressor action of liganded thyroid hormone receptor beta by direct repression of β-catenin gene expression Endocrinology 151 2010 5528 5536