Indexes of polar interactions between ionizable drugs and membrane phospholipids measured by IAM-HPLC: Their relationships with data of Blood-Brain Barrier passage

European Journal of Pharmaceutical Sciences

Volumn 65, Issue , 2014, Pages 139-146

  Grumetto, Lucia ^a   Russo, Giacomo ^a   Barbato, Francesco ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

BBB Blood Brain Barrier; IAM HPLC; Lipophilicity; Membrane; Phospholipids

Indexed keywords

ALPRAZOLAM; AMINOPHENAZONE; AMITRIPTYLINE; BETAHISTINE; BROMPERIDOL; CARBAMAZEPINE 10,11 OXIDE; CHLORAMBUCIL; CLOBAZAM; CODEINE; COTININE; DESIPRAMINE; DOMPERIDONE; FLUPHENAZINE; HEXOBARBITAL; HYDROXYZINE; MEMBRANE PHOSPHOLIPID; MEPYRAMINE; METHOHEXITAL; PHOSPHOLIPID; PHYSOSTIGMINE; PROPOFOL; RISPERIDONE; ARTIFICIAL MEMBRANE; DRUG; OCTANOL;

ARTICLE; ARTIFICIAL MEMBRANE; BLOOD BRAIN BARRIER; DRUG PENETRATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIPOPHILICITY; STATIC ELECTRICITY; CHEMICAL PHENOMENA; METABOLISM; PERMEABILITY; PHYSIOLOGY; PROCEDURES; TRANSPORT AT THE CELLULAR LEVEL;

1-OCTANOL; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MEMBRANES, ARTIFICIAL; PERMEABILITY; PHARMACEUTICAL PREPARATIONS; PHOSPHOLIPIDS; STATIC ELECTRICITY;

EID: 84908007900     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2014.09.015     Document Type: Article

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