-
1
-
-
0037096906
-
The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade
-
Albuquerque C., Breukel C., van der Luijt R., Fidalgo P., Lage P., Slors F.J., Leitão C.N., Fodde R., Smits R. The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade. Hum. Mol. Genet. 2002, 11:1549-1560.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1549-1560
-
-
Albuquerque, C.1
Breukel, C.2
van der Luijt, R.3
Fidalgo, P.4
Lage, P.5
Slors, F.J.6
Leitão, C.N.7
Fodde, R.8
Smits, R.9
-
2
-
-
28844455024
-
Constitutively active beta-catenin confers multilineage differentiation potential on lymphoid and myeloid progenitors
-
Baba Y., Garrett K.P., Kincade P.W. Constitutively active beta-catenin confers multilineage differentiation potential on lymphoid and myeloid progenitors. Immunity 2005, 23:599-609.
-
(2005)
Immunity
, vol.23
, pp. 599-609
-
-
Baba, Y.1
Garrett, K.P.2
Kincade, P.W.3
-
3
-
-
62049084688
-
Casein kinase 1alpha governs antigen-receptor-induced NF-kappaB activation and human lymphoma cell survival
-
Bidère N., Ngo V.N., Lee J., Collins C., Zheng L., Wan F., Davis R.E., Lenz G., Anderson D.E., Arnoult D., et al. Casein kinase 1alpha governs antigen-receptor-induced NF-kappaB activation and human lymphoma cell survival. Nature 2009, 458:92-96.
-
(2009)
Nature
, vol.458
, pp. 92-96
-
-
Bidère, N.1
Ngo, V.N.2
Lee, J.3
Collins, C.4
Zheng, L.5
Wan, F.6
Davis, R.E.7
Lenz, G.8
Anderson, D.E.9
Arnoult, D.10
-
4
-
-
35748956094
-
Gene expression profiling of CD34+ cells in patients with the 5q- syndrome
-
Boultwood J., Pellagatti A., Cattan H., Lawrie C.H., Giagounidis A., Malcovati L., Della Porta M.G., Jädersten M., Killick S., Fidler C., et al. Gene expression profiling of CD34+ cells in patients with the 5q- syndrome. Br. J. Haematol. 2007, 139:578-589.
-
(2007)
Br. J. Haematol.
, vol.139
, pp. 578-589
-
-
Boultwood, J.1
Pellagatti, A.2
Cattan, H.3
Lawrie, C.H.4
Giagounidis, A.5
Malcovati, L.6
Della Porta, M.G.7
Jädersten, M.8
Killick, S.9
Fidler, C.10
-
5
-
-
78650668810
-
Advances in the 5q- syndrome
-
Boultwood J., Pellagatti A., McKenzie A.N., Wainscoat J.S. Advances in the 5q- syndrome. Blood 2010, 116:5803-5811.
-
(2010)
Blood
, vol.116
, pp. 5803-5811
-
-
Boultwood, J.1
Pellagatti, A.2
McKenzie, A.N.3
Wainscoat, J.S.4
-
6
-
-
79551648987
-
Knockdown of Hspa9, a del(5q31.2) gene, results in a decrease in hematopoietic progenitors in mice
-
Chen T.H., Kambal A., Krysiak K., Walshauser M.A., Raju G., Tibbitts J.F., Walter M.J. Knockdown of Hspa9, a del(5q31.2) gene, results in a decrease in hematopoietic progenitors in mice. Blood 2011, 117:1530-1539.
-
(2011)
Blood
, vol.117
, pp. 1530-1539
-
-
Chen, T.H.1
Kambal, A.2
Krysiak, K.3
Walshauser, M.A.4
Raju, G.5
Tibbitts, J.F.6
Walter, M.J.7
-
8
-
-
28644444440
-
Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction
-
Davidson G., Wu W., Shen J., Bilic J., Fenger U., Stannek P., Glinka A., Niehrs C. Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction. Nature 2005, 438:867-872.
-
(2005)
Nature
, vol.438
, pp. 867-872
-
-
Davidson, G.1
Wu, W.2
Shen, J.3
Bilic, J.4
Fenger, U.5
Stannek, P.6
Glinka, A.7
Niehrs, C.8
-
9
-
-
84878593111
-
Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity
-
Dulak A.M., Stojanov P., Peng S., Lawrence M.S., Fox C., Stewart C., Bandla S., Imamura Y., Schumacher S.E., Shefler E., et al. Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity. Nat. Genet. 2013, 45:478-486.
-
(2013)
Nat. Genet.
, vol.45
, pp. 478-486
-
-
Dulak, A.M.1
Stojanov, P.2
Peng, S.3
Lawrence, M.S.4
Fox, C.5
Stewart, C.6
Bandla, S.7
Imamura, Y.8
Schumacher, S.E.9
Shefler, E.10
-
10
-
-
79953117045
-
Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells
-
Dutt S., Narla A., Lin K., Mullally A., Abayasekara N., Megerdichian C., Wilson F.H., Currie T., Khanna-Gupta A., Berliner N., et al. Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells. Blood 2011, 117:2567-2576.
-
(2011)
Blood
, vol.117
, pp. 2567-2576
-
-
Dutt, S.1
Narla, A.2
Lin, K.3
Mullally, A.4
Abayasekara, N.5
Megerdichian, C.6
Wilson, F.H.7
Currie, T.8
Khanna-Gupta, A.9
Berliner, N.10
-
11
-
-
80053198659
-
Molecular dissection of the 5q deletion in myelodysplastic syndrome
-
Ebert B.L. Molecular dissection of the 5q deletion in myelodysplastic syndrome. Semin. Oncol. 2011, 38:621-626.
-
(2011)
Semin. Oncol.
, vol.38
, pp. 621-626
-
-
Ebert, B.L.1
-
12
-
-
38349088899
-
Identification of RPS14 as a 5q- syndrome gene by RNA interference screen
-
Ebert B.L., Pretz J., Bosco J., Chang C.Y., Tamayo P., Galili N., Raza A., Root D.E., Attar E., Ellis S.R., Golub T.R. Identification of RPS14 as a 5q- syndrome gene by RNA interference screen. Nature 2008, 451:335-339.
-
(2008)
Nature
, vol.451
, pp. 335-339
-
-
Ebert, B.L.1
Pretz, J.2
Bosco, J.3
Chang, C.Y.4
Tamayo, P.5
Galili, N.6
Raza, A.7
Root, D.E.8
Attar, E.9
Ellis, S.R.10
Golub, T.R.11
-
13
-
-
79951784529
-
CKIα ablation highlights a critical role for p53 in invasiveness control
-
Elyada E., Pribluda A., Goldstein R.E., Morgenstern Y., Brachya G., Cojocaru G., Snir-Alkalay I., Burstain I., Haffner-Krausz R., Jung S., et al. CKIα ablation highlights a critical role for p53 in invasiveness control. Nature 2011, 470:409-413.
-
(2011)
Nature
, vol.470
, pp. 409-413
-
-
Elyada, E.1
Pribluda, A.2
Goldstein, R.E.3
Morgenstern, Y.4
Brachya, G.5
Cojocaru, G.6
Snir-Alkalay, I.7
Burstain, I.8
Haffner-Krausz, R.9
Jung, S.10
-
14
-
-
38949123096
-
Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML
-
Gondek L.P., Tiu R., O'Keefe C.L., Sekeres M.A., Theil K.S., Maciejewski J.P. Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML. Blood 2008, 111:1534-1542.
-
(2008)
Blood
, vol.111
, pp. 1534-1542
-
-
Gondek, L.P.1
Tiu, R.2
O'Keefe, C.L.3
Sekeres, M.A.4
Theil, K.S.5
Maciejewski, J.P.6
-
15
-
-
84887212500
-
Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis
-
Graubert T.A., Payton M.A., Shao J., Walgren R.A., Monahan R.S., Frater J.L., Walshauser M.A., Martin M.G., Kasai Y., Walter M.J. Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis. PLoS ONE 2009, 4:e4583.
-
(2009)
PLoS ONE
, vol.4
, pp. e4583
-
-
Graubert, T.A.1
Payton, M.A.2
Shao, J.3
Walgren, R.A.4
Monahan, R.S.5
Frater, J.L.6
Walshauser, M.A.7
Martin, M.G.8
Kasai, Y.9
Walter, M.J.10
-
16
-
-
84555192302
-
Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes
-
Graubert T.A., Shen D., Ding L., Okeyo-Owuor T., Lunn C.L., Shao J., Krysiak K., Harris C.C., Koboldt D.C., Larson D.E., et al. Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes. Nat. Genet. 2012, 44:53-57.
-
(2012)
Nat. Genet.
, vol.44
, pp. 53-57
-
-
Graubert, T.A.1
Shen, D.2
Ding, L.3
Okeyo-Owuor, T.4
Lunn, C.L.5
Shao, J.6
Krysiak, K.7
Harris, C.C.8
Koboldt, D.C.9
Larson, D.E.10
-
17
-
-
39649094569
-
New insights into the prognostic impact of the karyotype in MDS and correlation with subtypes: evidence from a core dataset of 2124 patients
-
Haase D., Germing U., Schanz J., Pfeilstöcker M., Nösslinger T., Hildebrandt B., Kundgen A., Lübbert M., Kunzmann R., Giagounidis A.A., et al. New insights into the prognostic impact of the karyotype in MDS and correlation with subtypes: evidence from a core dataset of 2124 patients. Blood 2007, 110:4385-4395.
-
(2007)
Blood
, vol.110
, pp. 4385-4395
-
-
Haase, D.1
Germing, U.2
Schanz, J.3
Pfeilstöcker, M.4
Nösslinger, T.5
Hildebrandt, B.6
Kundgen, A.7
Lübbert, M.8
Kunzmann, R.9
Giagounidis, A.A.10
-
18
-
-
68149162241
-
Myelodysplastic syndrome with isolated del(5q)
-
WHO Press, Geneva, Switzerland, S.H. Swerdlow, E. Campo, N.L. Harris, E.S. Jaffe, S.A. Pileri, H. Stein, J. Thiele, J.W. Vardiman (Eds.)
-
Hasserjian R.P., LeBeau M.M., List A.F., Bennett J.M., Thiele J. Myelodysplastic syndrome with isolated del(5q). WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues 2008, 102. WHO Press, Geneva, Switzerland. Fourth edition. S.H. Swerdlow, E. Campo, N.L. Harris, E.S. Jaffe, S.A. Pileri, H. Stein, J. Thiele, J.W. Vardiman (Eds.).
-
(2008)
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
, pp. 102
-
-
Hasserjian, R.P.1
LeBeau, M.M.2
List, A.F.3
Bennett, J.M.4
Thiele, J.5
-
19
-
-
70349306857
-
Accurate detection of uniparental disomy and microdeletions by SNP array analysis in myelodysplastic syndromes with normal cytogenetics
-
Heinrichs S., Kulkarni R.V., Bueso-Ramos C.E., Levine R.L., Loh M.L., Li C., Neuberg D., Kornblau S.M., Issa J.P., Gilliland D.G., et al. Accurate detection of uniparental disomy and microdeletions by SNP array analysis in myelodysplastic syndromes with normal cytogenetics. Leukemia 2009, 23:1605-1613.
-
(2009)
Leukemia
, vol.23
, pp. 1605-1613
-
-
Heinrichs, S.1
Kulkarni, R.V.2
Bueso-Ramos, C.E.3
Levine, R.L.4
Loh, M.L.5
Li, C.6
Neuberg, D.7
Kornblau, S.M.8
Issa, J.P.9
Gilliland, D.G.10
-
20
-
-
84897943177
-
Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia
-
Järås M., Miller P.G., Chu L.P., Puram R.V., Fink E.C., Schneider R.K., Al-Shahrour F., Peña P., Breyfogle L.J., Hartwell K.A., et al. Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia. J.Exp. Med. 2014, 211:605-612.
-
(2014)
J.Exp. Med.
, vol.211
, pp. 605-612
-
-
Järås, M.1
Miller, P.G.2
Chu, L.P.3
Puram, R.V.4
Fink, E.C.5
Schneider, R.K.6
Al-Shahrour, F.7
Peña, P.8
Breyfogle, L.J.9
Hartwell, K.A.10
-
21
-
-
84862248169
-
Topography, clinical, and genomic correlates of 5q myeloid malignancies revisited
-
Jerez A., Gondek L.P., Jankowska A.M., Makishima H., Przychodzen B., Tiu R.V., O'Keefe C.L., Mohamedali A.M., Batista D., Sekeres M.A., et al. Topography, clinical, and genomic correlates of 5q myeloid malignancies revisited. J.Clin. Oncol. 2012, 30:1343-1349.
-
(2012)
J.Clin. Oncol.
, vol.30
, pp. 1343-1349
-
-
Jerez, A.1
Gondek, L.P.2
Jankowska, A.M.3
Makishima, H.4
Przychodzen, B.5
Tiu, R.V.6
O'Keefe, C.L.7
Mohamedali, A.M.8
Batista, D.9
Sekeres, M.A.10
-
22
-
-
34547092452
-
Haploinsufficiency of EGR1, a candidate gene in the del(5q), leads to the development of myeloid disorders
-
Joslin J.M., Fernald A.A., Tennant T.R., Davis E.M., Kogan S.C., Anastasi J., Crispino J.D., Le Beau M.M. Haploinsufficiency of EGR1, a candidate gene in the del(5q), leads to the development of myeloid disorders. Blood 2007, 110:719-726.
-
(2007)
Blood
, vol.110
, pp. 719-726
-
-
Joslin, J.M.1
Fernald, A.A.2
Tennant, T.R.3
Davis, E.M.4
Kogan, S.C.5
Anastasi, J.6
Crispino, J.D.7
Le Beau, M.M.8
-
23
-
-
33748850636
-
Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block
-
Kirstetter P., Anderson K., Porse B.T., Jacobsen S.E., Nerlov C. Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block. Nat. Immunol. 2006, 7:1048-1056.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 1048-1056
-
-
Kirstetter, P.1
Anderson, K.2
Porse, B.T.3
Jacobsen, S.E.4
Nerlov, C.5
-
24
-
-
84863229597
-
VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing
-
Koboldt D.C., Zhang Q., Larson D.E., Shen D., McLellan M.D., Lin L., Miller C.A., Mardis E.R., Ding L., Wilson R.K. VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing. Genome Res. 2012, 22:568-576.
-
(2012)
Genome Res.
, vol.22
, pp. 568-576
-
-
Koboldt, D.C.1
Zhang, Q.2
Larson, D.E.3
Shen, D.4
McLellan, M.D.5
Lin, L.6
Miller, C.A.7
Mardis, E.R.8
Ding, L.9
Wilson, R.K.10
-
25
-
-
84893917461
-
Leukaemogenesis induced by an activating β-catenin mutation in osteoblasts
-
Kode A., Manavalan J.S., Mosialou I., Bhagat G., Rathinam C.V., Luo N., Khiabanian H., Lee A., Murty V.V., Friedman R., et al. Leukaemogenesis induced by an activating β-catenin mutation in osteoblasts. Nature 2014, 506:240-244.
-
(2014)
Nature
, vol.506
, pp. 240-244
-
-
Kode, A.1
Manavalan, J.S.2
Mosialou, I.3
Bhagat, G.4
Rathinam, C.V.5
Luo, N.6
Khiabanian, H.7
Lee, A.8
Murty, V.V.9
Friedman, R.10
-
26
-
-
80055071687
-
Coordinate loss of a microRNA and protein-coding gene cooperate in the pathogenesis of 5q- syndrome
-
Kumar M.S., Narla A., Nonami A., Mullally A., Dimitrova N., Ball B., McAuley J.R., Poveromo L., Kutok J.L., Galili N., et al. Coordinate loss of a microRNA and protein-coding gene cooperate in the pathogenesis of 5q- syndrome. Blood 2011, 118:4666-4673.
-
(2011)
Blood
, vol.118
, pp. 4666-4673
-
-
Kumar, M.S.1
Narla, A.2
Nonami, A.3
Mullally, A.4
Dimitrova, N.5
Ball, B.6
McAuley, J.R.7
Poveromo, L.8
Kutok, J.L.9
Galili, N.10
-
27
-
-
77951728570
-
The Apc(min) mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS
-
Lane S.W., Sykes S.M., Al-Shahrour F., Shterental S., Paktinat M., Lo Celso C., Jesneck J.L., Ebert B.L., Williams D.A., Gilliland D.G. The Apc(min) mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS. Blood 2010, 115:3489-3497.
-
(2010)
Blood
, vol.115
, pp. 3489-3497
-
-
Lane, S.W.1
Sykes, S.M.2
Al-Shahrour, F.3
Shterental, S.4
Paktinat, M.5
Lo Celso, C.6
Jesneck, J.L.7
Ebert, B.L.8
Williams, D.A.9
Gilliland, D.G.10
-
28
-
-
80053907201
-
Canonical wnt signaling regulates hematopoiesis in a dosage-dependent fashion
-
Luis T.C., Naber B.A., Roozen P.P., Brugman M.H., de Haas E.F., Ghazvini M., Fibbe W.E., van Dongen J.J., Fodde R., Staal F.J. Canonical wnt signaling regulates hematopoiesis in a dosage-dependent fashion. Cell Stem Cell 2011, 9:345-356.
-
(2011)
Cell Stem Cell
, vol.9
, pp. 345-356
-
-
Luis, T.C.1
Naber, B.A.2
Roozen, P.P.3
Brugman, M.H.4
de Haas, E.F.5
Ghazvini, M.6
Fibbe, W.E.7
van Dongen, J.J.8
Fodde, R.9
Staal, F.J.10
-
29
-
-
84857997303
-
Wnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia development
-
Luis T.C., Ichii M., Brugman M.H., Kincade P., Staal F.J. Wnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia development. Leukemia 2012, 26:414-421.
-
(2012)
Leukemia
, vol.26
, pp. 414-421
-
-
Luis, T.C.1
Ichii, M.2
Brugman, M.H.3
Kincade, P.4
Staal, F.J.5
-
30
-
-
84879121023
-
Response to lenalidomide in myelodysplastic syndromes with del(5q): influence of cytogenetics and mutations
-
Mallo M., Del Rey M., Ibáñez M., Calasanz M.J., Arenillas L., Larráyoz M.J., Pedro C., Jerez A., Maciejewski J., Costa D., et al. Response to lenalidomide in myelodysplastic syndromes with del(5q): influence of cytogenetics and mutations. Br. J. Haematol. 2013, 162:74-86.
-
(2013)
Br. J. Haematol.
, vol.162
, pp. 74-86
-
-
Mallo, M.1
Del Rey, M.2
Ibáñez, M.3
Calasanz, M.J.4
Arenillas, L.5
Larráyoz, M.J.6
Pedro, C.7
Jerez, A.8
Maciejewski, J.9
Costa, D.10
-
31
-
-
77956295988
-
The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data
-
McKenna A., Hanna M., Banks E., Sivachenko A., Cibulskis K., Kernytsky A., Garimella K., Altshuler D., Gabriel S., Daly M., DePristo M.A. The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. Genome Res. 2010, 20:1297-1303.
-
(2010)
Genome Res.
, vol.20
, pp. 1297-1303
-
-
McKenna, A.1
Hanna, M.2
Banks, E.3
Sivachenko, A.4
Cibulskis, K.5
Kernytsky, A.6
Garimella, K.7
Altshuler, D.8
Gabriel, S.9
Daly, M.10
DePristo, M.A.11
-
32
-
-
84880011146
-
InVivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling
-
Miller P.G., Al-Shahrour F., Hartwell K.A., Chu L.P., Järås M., Puram R.V., Puissant A., Callahan K.P., Ashton J., McConkey M.E., et al. InVivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling. Cancer Cell 2013, 24:45-58.
-
(2013)
Cancer Cell
, vol.24
, pp. 45-58
-
-
Miller, P.G.1
Al-Shahrour, F.2
Hartwell, K.A.3
Chu, L.P.4
Järås, M.5
Puram, R.V.6
Puissant, A.7
Callahan, K.P.8
Ashton, J.9
McConkey, M.E.10
-
33
-
-
41449118699
-
The transcription factor EGR1 controls both the proliferation and localization of hematopoietic stem cells
-
Min I.M., Pietramaggiori G., Kim F.S., Passegué E., Stevenson K.E., Wagers A.J. The transcription factor EGR1 controls both the proliferation and localization of hematopoietic stem cells. Cell Stem Cell 2008, 2:380-391.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 380-391
-
-
Min, I.M.1
Pietramaggiori, G.2
Kim, F.S.3
Passegué, E.4
Stevenson, K.E.5
Wagers, A.J.6
-
34
-
-
84865227709
-
Cancer vulnerabilities unveiled by genomic loss
-
Nijhawan D., Zack T.I., Ren Y., Strickland M.R., Lamothe R., Schumacher S.E., Tsherniak A., Besche H.C., Rosenbluh J., Shehata S., et al. Cancer vulnerabilities unveiled by genomic loss. Cell 2012, 150:842-854.
-
(2012)
Cell
, vol.150
, pp. 842-854
-
-
Nijhawan, D.1
Zack, T.I.2
Ren, Y.3
Strickland, M.R.4
Lamothe, R.5
Schumacher, S.E.6
Tsherniak, A.7
Besche, H.C.8
Rosenbluh, J.9
Shehata, S.10
-
35
-
-
0033598401
-
Casein kinase I transduces Wnt signals
-
Peters J.M., McKay R.M., McKay J.P., Graff J.M. Casein kinase I transduces Wnt signals. Nature 1999, 401:345-350.
-
(1999)
Nature
, vol.401
, pp. 345-350
-
-
Peters, J.M.1
McKay, R.M.2
McKay, J.P.3
Graff, J.M.4
-
36
-
-
1242276189
-
D4476, a cell-permeant inhibitor of CK1, suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a
-
Rena G., Bain J., Elliott M., Cohen P. D4476, a cell-permeant inhibitor of CK1, suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a. EMBO Rep. 2004, 5:60-65.
-
(2004)
EMBO Rep.
, vol.5
, pp. 60-65
-
-
Rena, G.1
Bain, J.2
Elliott, M.3
Cohen, P.4
-
37
-
-
84880967722
-
Integrated molecular analysis of clear-cell renal cell carcinoma
-
Sato Y., Yoshizato T., Shiraishi Y., Maekawa S., Okuno Y., Kamura T., Shimamura T., Sato-Otsubo A., Nagae G., Suzuki H., et al. Integrated molecular analysis of clear-cell renal cell carcinoma. Nat. Genet. 2013, 45:860-867.
-
(2013)
Nat. Genet.
, vol.45
, pp. 860-867
-
-
Sato, Y.1
Yoshizato, T.2
Shiraishi, Y.3
Maekawa, S.4
Okuno, Y.5
Kamura, T.6
Shimamura, T.7
Sato-Otsubo, A.8
Nagae, G.9
Suzuki, H.10
-
38
-
-
33748859509
-
Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation
-
Scheller M., Huelsken J., Rosenbauer F., Taketo M.M., Birchmeier W., Tenen D.G., Leutz A. Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation. Nat. Immunol. 2006, 7:1037-1047.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 1037-1047
-
-
Scheller, M.1
Huelsken, J.2
Rosenbauer, F.3
Taketo, M.M.4
Birchmeier, W.5
Tenen, D.G.6
Leutz, A.7
-
39
-
-
77956297018
-
Suppression of casein kinase 1alpha in melanoma cells induces a switch in beta-catenin signaling to promote metastasis
-
Sinnberg T., Menzel M., Kaesler S., Biedermann T., Sauer B., Nahnsen S., Schwarz M., Garbe C., Schittek B. Suppression of casein kinase 1alpha in melanoma cells induces a switch in beta-catenin signaling to promote metastasis. Cancer Res. 2010, 70:6999-7009.
-
(2010)
Cancer Res.
, vol.70
, pp. 6999-7009
-
-
Sinnberg, T.1
Menzel, M.2
Kaesler, S.3
Biedermann, T.4
Sauer, B.5
Nahnsen, S.6
Schwarz, M.7
Garbe, C.8
Schittek, B.9
-
40
-
-
73849121794
-
Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype
-
Starczynowski D.T., Kuchenbauer F., Argiropoulos B., Sung S., Morin R., Muranyi A., Hirst M., Hogge D., Marra M., Wells R.A., et al. Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype. Nat. Med. 2010, 16:49-58.
-
(2010)
Nat. Med.
, vol.16
, pp. 49-58
-
-
Starczynowski, D.T.1
Kuchenbauer, F.2
Argiropoulos, B.3
Sung, S.4
Morin, R.5
Muranyi, A.6
Hirst, M.7
Hogge, D.8
Marra, M.9
Wells, R.A.10
-
41
-
-
84898779089
-
Haploinsufficiency of del(5q) genes, Egr1 and Apc, cooperate with Tp53 loss to induce acute myeloid leukemia in mice
-
Stoddart A., Fernald A.A., Wang J., Davis E.M., Karrison T., Anastasi J., Le Beau M.M. Haploinsufficiency of del(5q) genes, Egr1 and Apc, cooperate with Tp53 loss to induce acute myeloid leukemia in mice. Blood 2014, 123:1069-1078.
-
(2014)
Blood
, vol.123
, pp. 1069-1078
-
-
Stoddart, A.1
Fernald, A.A.2
Wang, J.3
Davis, E.M.4
Karrison, T.5
Anastasi, J.6
Le Beau, M.M.7
-
42
-
-
30044444251
-
Glycogen synthase kinase-3 is an invivo regulator of hematopoietic stem cell repopulation
-
Trowbridge J.J., Xenocostas A., Moon R.T., Bhatia M. Glycogen synthase kinase-3 is an invivo regulator of hematopoietic stem cell repopulation. Nat. Med. 2006, 12:89-98.
-
(2006)
Nat. Med.
, vol.12
, pp. 89-98
-
-
Trowbridge, J.J.1
Xenocostas, A.2
Moon, R.T.3
Bhatia, M.4
-
43
-
-
34250331610
-
A microenvironment-induced myeloproliferative syndrome caused by retinoic acid receptor gamma deficiency
-
Walkley C.R., Olsen G.H., Dworkin S., Fabb S.A., Swann J., McArthur G.A., Westmoreland S.V., Chambon P., Scadden D.T., Purton L.E. A microenvironment-induced myeloproliferative syndrome caused by retinoic acid receptor gamma deficiency. Cell 2007, 129:1097-1110.
-
(2007)
Cell
, vol.129
, pp. 1097-1110
-
-
Walkley, C.R.1
Olsen, G.H.2
Dworkin, S.3
Fabb, S.A.4
Swann, J.5
McArthur, G.A.6
Westmoreland, S.V.7
Chambon, P.8
Scadden, D.T.9
Purton, L.E.10
-
44
-
-
77951757238
-
Haploinsufficiency of Apc leads to ineffective hematopoiesis
-
Wang J., Fernald A.A., Anastasi J., Le Beau M.M., Qian Z. Haploinsufficiency of Apc leads to ineffective hematopoiesis. Blood 2010, 115:3481-3488.
-
(2010)
Blood
, vol.115
, pp. 3481-3488
-
-
Wang, J.1
Fernald, A.A.2
Anastasi, J.3
Le Beau, M.M.4
Qian, Z.5
-
45
-
-
77950287628
-
The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML
-
Wang Y., Krivtsov A.V., Sinha A.U., North T.E., Goessling W., Feng Z., Zon L.I., Armstrong S.A. The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML. Science 2010, 327:1650-1653.
-
(2010)
Science
, vol.327
, pp. 1650-1653
-
-
Wang, Y.1
Krivtsov, A.V.2
Sinha, A.U.3
North, T.E.4
Goessling, W.5
Feng, Z.6
Zon, L.I.7
Armstrong, S.A.8
-
46
-
-
0037737726
-
Wnt proteins are lipid-modified and can act as stem cell growth factors
-
Willert K., Brown J.D., Danenberg E., Duncan A.W., Weissman I.L., Reya T., Yates J.R., Nusse R. Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature 2003, 423:448-452.
-
(2003)
Nature
, vol.423
, pp. 448-452
-
-
Willert, K.1
Brown, J.D.2
Danenberg, E.3
Duncan, A.W.4
Weissman, I.L.5
Reya, T.6
Yates, J.R.7
Nusse, R.8
-
47
-
-
84902480315
-
Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells invivo
-
Woll P.S., Kjällquist U., Chowdhury O., Doolittle H., Wedge D.C., Thongjuea S., Erlandsson R., Ngara M., Anderson K., Deng Q., et al. Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells invivo. Cancer Cell 2014, 25:794-808.
-
(2014)
Cancer Cell
, vol.25
, pp. 794-808
-
-
Woll, P.S.1
Kjällquist, U.2
Chowdhury, O.3
Doolittle, H.4
Wedge, D.C.5
Thongjuea, S.6
Erlandsson, R.7
Ngara, M.8
Anderson, K.9
Deng, Q.10
-
48
-
-
84871884749
-
Casein kinase 1α regulates an MDMX intramolecular interaction to stimulate p53 binding
-
Wu S., Chen L., Becker A., Schonbrunn E., Chen J. Casein kinase 1α regulates an MDMX intramolecular interaction to stimulate p53 binding. Mol. Cell. Biol. 2012, 32:4821-4832.
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 4821-4832
-
-
Wu, S.1
Chen, L.2
Becker, A.3
Schonbrunn, E.4
Chen, J.5
-
49
-
-
38349183265
-
Clinical significance of nuclear non-phosphorylated beta-catenin in acute myeloid leukaemia and myelodysplastic syndrome
-
Xu J., Suzuki M., Niwa Y., Hiraga J., Nagasaka T., Ito M., Nakamura S., Tomita A., Abe A., Kiyoi H., et al. Clinical significance of nuclear non-phosphorylated beta-catenin in acute myeloid leukaemia and myelodysplastic syndrome. Br. J. Haematol. 2008, 140:394-401.
-
(2008)
Br. J. Haematol.
, vol.140
, pp. 394-401
-
-
Xu, J.1
Suzuki, M.2
Niwa, Y.3
Hiraga, J.4
Nagasaka, T.5
Ito, M.6
Nakamura, S.7
Tomita, A.8
Abe, A.9
Kiyoi, H.10
-
50
-
-
78650003931
-
β-Catenin mediates the establishment and drug resistance of MLL leukemic stem cells
-
Yeung J., Esposito M.T., Gandillet A., Zeisig B.B., Griessinger E., Bonnet D., So C.W. β-Catenin mediates the establishment and drug resistance of MLL leukemic stem cells. Cancer Cell 2010, 18:606-618.
-
(2010)
Cancer Cell
, vol.18
, pp. 606-618
-
-
Yeung, J.1
Esposito, M.T.2
Gandillet, A.3
Zeisig, B.B.4
Griessinger, E.5
Bonnet, D.6
So, C.W.7
-
51
-
-
77749320194
-
A protocol for isolation and culture of mesenchymal stem cells from mouse compact bone
-
Zhu H., Guo Z.K., Jiang X.X., Li H., Wang X.Y., Yao H.Y., Zhang Y., Mao N. A protocol for isolation and culture of mesenchymal stem cells from mouse compact bone. Nat. Protoc. 2010, 5:550-560.
-
(2010)
Nat. Protoc.
, vol.5
, pp. 550-560
-
-
Zhu, H.1
Guo, Z.K.2
Jiang, X.X.3
Li, H.4
Wang, X.Y.5
Yao, H.Y.6
Zhang, Y.7
Mao, N.8
|