메뉴 건너뛰기




Volumn 26, Issue 4, 2014, Pages 521-533

Hedgehog signaling restrains bladder cancer progression by eliciting stromal production of urothelial differentiation factors

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 5; SONIC HEDGEHOG PROTEIN;

EID: 84907996793     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccell.2014.09.001     Document Type: Article
Times cited : (171)

References (51)
  • 1
    • 27144487469 scopus 로고    scopus 로고
    • Invivo analysis of quiescent adult neural stem cells responding to Sonic hedgehog
    • Ahn S., Joyner A.L. Invivo analysis of quiescent adult neural stem cells responding to Sonic hedgehog. Nature 2005, 437:894-897.
    • (2005) Nature , vol.437 , pp. 894-897
    • Ahn, S.1    Joyner, A.L.2
  • 3
    • 0017755913 scopus 로고
    • The pathogenesis of experimental bladder cancer
    • Bryan G.T. The pathogenesis of experimental bladder cancer. Cancer Res. 1977, 37:2813-2816.
    • (1977) Cancer Res. , vol.37 , pp. 2813-2816
    • Bryan, G.T.1
  • 4
    • 0020644903 scopus 로고
    • Pathogenesis of human urinary bladder cancer
    • Bryan G.T. Pathogenesis of human urinary bladder cancer. Environ. Health Perspect. 1983, 49:201-207.
    • (1983) Environ. Health Perspect. , vol.49 , pp. 201-207
    • Bryan, G.T.1
  • 5
    • 84897022815 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of urothelial bladder carcinoma
    • Cancer Genome Atlas Research Network
    • Comprehensive molecular characterization of urothelial bladder carcinoma. Nature 2014, 507:315-322. Cancer Genome Atlas Research Network.
    • (2014) Nature , vol.507 , pp. 315-322
  • 6
    • 0036829397 scopus 로고    scopus 로고
    • Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened
    • Chen J.K., Taipale J., Cooper M.K., Beachy P.A. Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened. Genes Dev. 2002, 16:2743-2748.
    • (2002) Genes Dev. , vol.16 , pp. 2743-2748
    • Chen, J.K.1    Taipale, J.2    Cooper, M.K.3    Beachy, P.A.4
  • 8
    • 84893520397 scopus 로고    scopus 로고
    • Identification of distinct basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapy
    • Choi W., Porten S., Kim S., Willis D., Plimack E.R., Hoffman-Censits J., Roth B., Cheng T., Tran M., Lee I.-L., et al. Identification of distinct basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapy. Cancer Cell 2014, 25:152-165.
    • (2014) Cancer Cell , vol.25 , pp. 152-165
    • Choi, W.1    Porten, S.2    Kim, S.3    Willis, D.4    Plimack, E.R.5    Hoffman-Censits, J.6    Roth, B.7    Cheng, T.8    Tran, M.9    Lee, I.-L.10
  • 9
    • 0032486433 scopus 로고    scopus 로고
    • Teratogen-mediated inhibition of target tissue response to Shh signaling
    • Cooper M.K., Porter J.A., Young K.E., Beachy P.A. Teratogen-mediated inhibition of target tissue response to Shh signaling. Science 1998, 280:1603-1607.
    • (1998) Science , vol.280 , pp. 1603-1607
    • Cooper, M.K.1    Porter, J.A.2    Young, K.E.3    Beachy, P.A.4
  • 10
    • 67649667324 scopus 로고    scopus 로고
    • SnapShot: Ca2+-calcineurin-NFAT signaling
    • Crabtree G.R., Schreiber S.L. SnapShot: Ca2+-calcineurin-NFAT signaling. Cell 2009, 138:210-210.e211.
    • (2009) Cell , vol.138 , pp. 210-210.e211
    • Crabtree, G.R.1    Schreiber, S.L.2
  • 13
    • 84883510623 scopus 로고    scopus 로고
    • New cast for a new era: preclinical cancer drug development revisited
    • Herter-Sprie G.S., Kung A.L., Wong K.-K. New cast for a new era: preclinical cancer drug development revisited. J.Clin. Invest. 2013, 123:3639-3645.
    • (2013) J.Clin. Invest. , vol.123 , pp. 3639-3645
    • Herter-Sprie, G.S.1    Kung, A.L.2    Wong, K.-K.3
  • 15
    • 0031723219 scopus 로고    scopus 로고
    • The teratogenic Veratrum alkaloid cyclopamine inhibits sonic hedgehog signal transduction
    • Incardona J.P., Gaffield W., Kapur R.P., Roelink H. The teratogenic Veratrum alkaloid cyclopamine inhibits sonic hedgehog signal transduction. Development 1998, 125:3553-3562.
    • (1998) Development , vol.125 , pp. 3553-3562
    • Incardona, J.P.1    Gaffield, W.2    Kapur, R.P.3    Roelink, H.4
  • 17
    • 0034894756 scopus 로고    scopus 로고
    • Characterization of human bone morphogenetic protein (BMP)-4 and -7 gene promoters: activation of BMP promoters by Gli, a sonic hedgehog mediator
    • Kawai S., Sugiura T. Characterization of human bone morphogenetic protein (BMP)-4 and -7 gene promoters: activation of BMP promoters by Gli, a sonic hedgehog mediator. Bone 2001, 29:54-61.
    • (2001) Bone , vol.29 , pp. 54-61
    • Kawai, S.1    Sugiura, T.2
  • 19
    • 20444433526 scopus 로고    scopus 로고
    • Gli1 is important for medulloblastoma formation in Ptc1+/- mice
    • Kimura H., Stephen D., Joyner A., Curran T. Gli1 is important for medulloblastoma formation in Ptc1+/- mice. Oncogene 2005, 24:4026-4036.
    • (2005) Oncogene , vol.24 , pp. 4026-4036
    • Kimura, H.1    Stephen, D.2    Joyner, A.3    Curran, T.4
  • 20
    • 0037218819 scopus 로고    scopus 로고
    • Sonic hedgehog regulates adult neural progenitor proliferation invitro and invivo
    • Lai K., Kaspar B.K., Gage F.H., Schaffer D.V. Sonic hedgehog regulates adult neural progenitor proliferation invitro and invivo. Nat. Neurosci. 2003, 6:21-27.
    • (2003) Nat. Neurosci. , vol.6 , pp. 21-27
    • Lai, K.1    Kaspar, B.K.2    Gage, F.H.3    Schaffer, D.V.4
  • 22
    • 79961123152 scopus 로고    scopus 로고
    • RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
    • Li B., Dewey C.N. RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. BMC Bioinformatics 2011, 12:323-338.
    • (2011) BMC Bioinformatics , vol.12 , pp. 323-338
    • Li, B.1    Dewey, C.N.2
  • 23
    • 0025893168 scopus 로고
    • Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
    • Liu J., Farmer J.D., Lane W.S., Friedman J., Weissman I., Schreiber S.L. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 1991, 66:807-815.
    • (1991) Cell , vol.66 , pp. 807-815
    • Liu, J.1    Farmer, J.D.2    Lane, W.S.3    Friedman, J.4    Weissman, I.5    Schreiber, S.L.6
  • 24
    • 0035691559 scopus 로고    scopus 로고
    • Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation
    • Long F., Zhang X.M., Karp S., Yang Y., McMahon A.P. Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation. Development 2001, 128:5099-5108.
    • (2001) Development , vol.128 , pp. 5099-5108
    • Long, F.1    Zhang, X.M.2    Karp, S.3    Yang, Y.4    McMahon, A.P.5
  • 25
    • 0037167519 scopus 로고    scopus 로고
    • Id: a target of BMP signaling
    • Miyazono K., Miyazawa K. Id: a target of BMP signaling. Sci. STKE 2002, 2002:pe40.
    • (2002) Sci. STKE , vol.2002 , pp. pe40
    • Miyazono, K.1    Miyazawa, K.2
  • 26
    • 21344455768 scopus 로고    scopus 로고
    • BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk
    • Miyazono K., Maeda S., Imamura T. BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk. Cytokine Growth Factor Rev. 2005, 16:251-263.
    • (2005) Cytokine Growth Factor Rev. , vol.16 , pp. 251-263
    • Miyazono, K.1    Maeda, S.2    Imamura, T.3
  • 27
    • 65549083387 scopus 로고    scopus 로고
    • Bone morphogenetic protein 4 signaling regulates epithelial renewal in the urinary tract in response to uropathogenic infection
    • Mysorekar I.U., Isaacson-Schmid M., Walker J.N., Mills J.C., Hultgren S.J. Bone morphogenetic protein 4 signaling regulates epithelial renewal in the urinary tract in response to uropathogenic infection. Cell Host Microbe 2009, 5:463-475.
    • (2009) Cell Host Microbe , vol.5 , pp. 463-475
    • Mysorekar, I.U.1    Isaacson-Schmid, M.2    Walker, J.N.3    Mills, J.C.4    Hultgren, S.J.5
  • 28
    • 0017334803 scopus 로고
    • Mutagenicity of N-butyl-N-(4-hydroxybutyl)nitrosamine, a bladder carcinogen, and related compounds
    • Nagao M., Suzuki E., Yasuo K., Yahagi T., Seino Y. Mutagenicity of N-butyl-N-(4-hydroxybutyl)nitrosamine, a bladder carcinogen, and related compounds. Cancer Res. 1977, 37:399-407.
    • (1977) Cancer Res. , vol.37 , pp. 399-407
    • Nagao, M.1    Suzuki, E.2    Yasuo, K.3    Yahagi, T.4    Seino, Y.5
  • 29
    • 0018143293 scopus 로고
    • Ultrastructure, karyology and immunology of a cell line originated from a human transitional-cell carcinoma
    • O'Toole C., Price Z.H., Ohnuki Y., Unsgaard B. Ultrastructure, karyology and immunology of a cell line originated from a human transitional-cell carcinoma. Br. J. Cancer 1978, 38:64-76.
    • (1978) Br. J. Cancer , vol.38 , pp. 64-76
    • O'Toole, C.1    Price, Z.H.2    Ohnuki, Y.3    Unsgaard, B.4
  • 34
    • 0028875032 scopus 로고
    • Sonic hedgehog is an endodermal signal inducing Bmp-4 and Hox genes during induction and regionalization of the chick hindgut
    • Roberts D.J., Johnson R.L., Burke A.C., Nelson C.E., Morgan B.A., Tabin C. Sonic hedgehog is an endodermal signal inducing Bmp-4 and Hox genes during induction and regionalization of the chick hindgut. Development 1995, 121:3163-3174.
    • (1995) Development , vol.121 , pp. 3163-3174
    • Roberts, D.J.1    Johnson, R.L.2    Burke, A.C.3    Nelson, C.E.4    Morgan, B.A.5    Tabin, C.6
  • 35
    • 0029004233 scopus 로고
    • Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis
    • Roelink H., Porter J.A., Chiang C., Tanabe Y., Chang D.T., Beachy P.A., Jessell T.M. Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis. Cell 1995, 81:445-455.
    • (1995) Cell , vol.81 , pp. 445-455
    • Roelink, H.1    Porter, J.A.2    Chiang, C.3    Tanabe, Y.4    Chang, D.T.5    Beachy, P.A.6    Jessell, T.M.7
  • 36
    • 84878643242 scopus 로고    scopus 로고
    • Hedgehog signaling pathway and cancer therapeutics: progress to date
    • Ruch J.M., Kim E.J. Hedgehog signaling pathway and cancer therapeutics: progress to date. Drugs 2013, 73:613-623.
    • (2013) Drugs , vol.73 , pp. 613-623
    • Ruch, J.M.1    Kim, E.J.2
  • 38
    • 4644223417 scopus 로고    scopus 로고
    • Interactions between ID and OLIG proteins mediate the inhibitory effects of BMP4 on oligodendroglial differentiation
    • Samanta J., Kessler J.A. Interactions between ID and OLIG proteins mediate the inhibitory effects of BMP4 on oligodendroglial differentiation. Development 2004, 131:4131-4142.
    • (2004) Development , vol.131 , pp. 4131-4142
    • Samanta, J.1    Kessler, J.A.2
  • 39
    • 0031018002 scopus 로고    scopus 로고
    • A role for bone morphogenetic proteins in the induction of cardiac myogenesis
    • Schultheiss T.M., Burch J.B., Lassar A.B. A role for bone morphogenetic proteins in the induction of cardiac myogenesis. Genes Dev. 1997, 11:451-462.
    • (1997) Genes Dev. , vol.11 , pp. 451-462
    • Schultheiss, T.M.1    Burch, J.B.2    Lassar, A.B.3
  • 41
    • 79953746223 scopus 로고    scopus 로고
    • Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder
    • Shin K., Lee J., Guo N., Kim J., Lim A., Qu L., Mysorekar I.U., Beachy P.A. Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder. Nature 2011, 472:110-114.
    • (2011) Nature , vol.472 , pp. 110-114
    • Shin, K.1    Lee, J.2    Guo, N.3    Kim, J.4    Lim, A.5    Qu, L.6    Mysorekar, I.U.7    Beachy, P.A.8
  • 45
    • 0035902140 scopus 로고    scopus 로고
    • The Hedgehog and Wnt signalling pathways in cancer
    • Taipale J., Beachy P.A. The Hedgehog and Wnt signalling pathways in cancer. Nature 2001, 411:349-354.
    • (2001) Nature , vol.411 , pp. 349-354
    • Taipale, J.1    Beachy, P.A.2
  • 47
    • 77649337790 scopus 로고    scopus 로고
    • Hedgehog beyond medulloblastoma and basal cell carcinoma
    • Teglund S., Toftgård R. Hedgehog beyond medulloblastoma and basal cell carcinoma. Biochim. Biophys. Acta 2010, 1805:181-208.
    • (2010) Biochim. Biophys. Acta , vol.1805 , pp. 181-208
    • Teglund, S.1    Toftgård, R.2
  • 48
    • 16344364134 scopus 로고    scopus 로고
    • Hedgehog signaling in normal urothelial cells and in urothelial carcinoma cell lines
    • Thievessen I., Wolter M., Prior A., Seifert H.H., Schulz W.A. Hedgehog signaling in normal urothelial cells and in urothelial carcinoma cell lines. J.Cell. Physiol. 2005, 203:372-377.
    • (2005) J.Cell. Physiol. , vol.203 , pp. 372-377
    • Thievessen, I.1    Wolter, M.2    Prior, A.3    Seifert, H.H.4    Schulz, W.A.5
  • 49
    • 0032857527 scopus 로고    scopus 로고
    • Bmp signaling regulates proximal-distal differentiation of endoderm in mouse lung development
    • Weaver M., Yingling J.M., Dunn N.R., Bellusci S., Hogan B.L. Bmp signaling regulates proximal-distal differentiation of endoderm in mouse lung development. Development 1999, 126:4005-4015.
    • (1999) Development , vol.126 , pp. 4005-4015
    • Weaver, M.1    Yingling, J.M.2    Dunn, N.R.3    Bellusci, S.4    Hogan, B.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.