Shensong Yangxin Capsule prevents diabetic myocardial fibrosis by inhibiting TGF-β1/Smad signaling

Journal of Ethnopharmacology

Volumn 157, Issue , 2014, Pages 161-170

  Shen, Nannan ^a   Li, Xiaoguang ^a   Zhou, Tong ^a   Bilal, Muhammad U ^a   Du, Ning ^a   Hu, Yingying ^a   Qin, Wei ^a   Xie, Yingming ^b   Wang, Hongtao ^c   Wu, Jianwei ^a   Ju, Jiaming ^a   Fang, Zhiwei ^a   Wang, Lihong ^b   Zhang, Yong ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

^c Hebei Yiling Pharmaceutical Group   (China)

Author keywords

Cardiac fibrosis; Diabetic cardiomyopathy; Shensong Yangxin Capsule; Smad; TGF 1

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANTIFIBROTIC AGENT; CHINESE DRUG; COLLAGEN TYPE 1; COLLAGEN TYPE 3; GELATINASE A; GELATINASE B; GLUCOSE; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; MESSENGER RNA; SHENSONG YANGXIN CAPSULE; SMAD PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; HERBACEOUS AGENT; SHENSONGYANGXIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL PROLIFERATION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; COPTIS CHINENSIS; CORNUS; DIABETIC CARDIOMYOPATHY; DOWN REGULATION; DRUG SYNTHESIS; EUPOLYPHAGA SINENSIS; FIBROBLAST; GINSENG; GLUCOSE BLOOD LEVEL; HEART FUNCTION; HEART MUSCLE FIBROSIS; HEART WEIGHT; HISTOPATHOLOGY; IMMUNOFLUORESCENCE; JUJUBE; LIPID DIET; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OPHIOPOGON JAPONICAS; PAEONIA LACTIFLORA; POLYPODIODES CHINENSIS; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SALVIA MILTIORRHIZA; SCHISANDRA SPHENANTHERA; SIGNAL TRANSDUCTION; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; TAXILLUS CHINENSIS; TRANSMISSION ELECTRON MICROSCOPY; TRANSTHORACIC ECHOCARDIOGRAPHY; UPREGULATION; VALERIANA JATAMANSI; WESTERN BLOTTING; ANIMAL; COMPLICATION; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC CARDIOMYOPATHIES; DRUG EFFECTS; FIBROSIS; HEART MUSCLE; METABOLISM; PATHOLOGY; WISTAR RAT;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC CARDIOMYOPATHIES; DOWN-REGULATION; DRUGS, CHINESE HERBAL; FIBROSIS; MALE; MYOCARDIUM; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

EID: 84907992346     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.09.035     Document Type: Article

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