A refined-JinQi-JiangTang tablet ameliorates prediabetes by reducing insulin resistance and improving beta cell function in mice

Journal of Ethnopharmacology

Volumn 151, Issue 1, 2014, Pages 675-685

  Gao, Li Hui ^a   Liu, Quan ^a   Liu, Shuai Nan ^a   Chen, Zhi Yu ^a   Li, Cai Na ^a   Lei, Lei ^a   Sun, Su Juan ^a   Li, Lin Yi ^a   Liu, Jing Long ^a   Shen, Zhu Fang ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Beta cell function; Herbal effective fractions; High fat diet; Insulin resistance; Prediabetes

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ANTIDIABETIC AGENT; CHOLESTEROL; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; JQ R; METFORMIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; BODY WEIGHT; CELL FUNCTION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG DOSE COMPARISON; ENZYME PHOSPHORYLATION; EXPERIMENTAL OBESITY; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE INFUSION; HISTOPATHOLOGY; HYPERCHOLESTEROLEMIA; IMPAIRED GLUCOSE TOLERANCE; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; LIPID BLOOD LEVEL; LIPID DIET; MALE; MOUSE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET BETA CELL; TABLET; TRIACYLGLYCEROL BLOOD LEVEL;

ASTRAGALUS MEMBRANACEUS; CAPRIFOLIACEAE; COPTIS CHINENSIS; FABACEAE; LONICERA JAPONICA; MUS; RANUNCULACEAE;

ACC; ACETYL COA CARBOXYLASE; ADENOSINE MONOPHOSPHATE-ACTIVATED PROTEIN KINASE; AMPK; AREA UNDER THE CURVES; AUC; BETA CELL FUNCTION; CON; ELSD; EVAPORATIVE LIGHT SCATTERING DETECTOR; GIR; GLUCOSE INFUSION RATE; GLUCOSE TRANSPORTER 2; GLUT2; GROUP TREATED WITH METFORMIN; HERBAL EFFECTIVE FRACTIONS; HFD; HIGH FAT DIET; HIGH FAT-DIET; HOMA-IR; HOMEOSTASIS MODEL ASSESSMENT RATIO OF INSULIN RESISTANCE; IFG; IGT; IMPAIRED FASTING GLUCOSE; IMPAIRED GLUCOSE TOLERANCE; INSULIN RESISTANCE; INSULIN TOLERANCE TEST; INTEGRATED OPTICAL DENSITY; IOD; IR; ITT; JQ-R; MET; NOR; NORMAL CONTROL; OGTT; ORAL GLUCOSE TOLERANCE TEST; PREDIABETES; REFINED-JINQI-JIANGTANG TABLET; S.E.M; STANDARD ERROR OF MEAN; T2DM; TC; TG; TOTAL CHOLESTEROL; TOTAL TRIGLYCERIDE; TYPE 2 DIABETES MELLITUS; UNTREATED CONTROL GROUP;

ANIMALS; BLOOD GLUCOSE; DIETARY FATS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; HYPOGLYCEMIC AGENTS; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; MICE; MICE, INBRED C57BL; PREDIABETIC STATE; WEIGHT-BEARING;

EID: 84891483344     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.11.024     Document Type: Article

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