Studies on excretion kinetics of ten constituents in rat urine after oral administration of Shensong Yangxin Capsule by UPLC-MS/MS

Biomedical Chromatography

Volumn 28, Issue 4, 2014, Pages 525-533

  Liu, Minyan ^a,b   Li, Song ^b   Zhao, Shaohua ^b   Wang, Hongtao ^b   Wang, Hairong ^b   Tu, Pengfei ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b Shijiazhuang Yiling Pharmaceutical Co Ltd   (China)

Author keywords

Multiple reaction monitoring; Shensong Yangxin Capsule; Solid phase extraction; UPLC MS MS; Urinary excretion kinetics

Indexed keywords

BODY FLUIDS; ELECTROSPRAY IONIZATION; EXTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHASE SEPARATION; PHYSIOLOGY; RATS;

MULTIPLE REACTION MONITORING; ORAL ADMINISTRATION; RAT URINE; SHENSONG YANGXIN CAPSULE; SOLID-PHASE EXTRACTION; ULTRA HIGH PERFORMANCE LIQUID CHROMATOGRAPHY-MASS SPECTROMETRIES; UPLC-MS/MS; URINARY EXCRETION; URINARY EXCRETION KINETIC; URINE SAMPLE;

KINETICS;

ACETONITRILE; ALKALOID DERIVATIVE; BERBERINE; CHINESE DRUG; COPTISINE; DEOXYSCHIZANDRIN; EPIBERBERINE; FLAVONOID; FORMIC ACID; HERBACEOUS AGENT; LIGNAN DERIVATIVE; LOGANIN; MORRONISIDE; PAEONIFLORIN; PALMATINE; SCHISANTHERIN A; SHENSONG YANGXIN CAPSULE; SPINOSIN; TERPENOID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTICLE; CHROMATOGRAPHY; CONTROLLED STUDY; DRUG CAPSULE; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; IONIZATION; MALE; MEASUREMENT ACCURACY; NONHUMAN; RAT; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; URINALYSIS; URINARY EXCRETION; URINE FLOW RATE;

RATTUS;

MULTIPLE-REACTION MONITORING; SHENSONG YANGXIN CAPSULE; SOLID-PHASE EXTRACTION; UPLC-MS/MS; URINARY EXCRETION KINETICS;

ADMINISTRATION, ORAL; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUGS, CHINESE HERBAL; LIMIT OF DETECTION; LINEAR MODELS; MALE; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

EID: 84896546924     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.3064     Document Type: Article

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