Lynch Syndrome in patients with clear cell and endometrioid cancers of the ovary

Gynecologic Oncology

Volumn 135, Issue 1, 2014, Pages 81-84

  Vierkoetter, Koah R ^a   Ayabe, Asia R ^a   Vandrunen, Maya ^a   Ahn, Hyeong Jun ^a   Shimizu, David M ^a   Terada, Keith Y ^a  

^a UNIVERSITY OF HAWAII   (United States)

Author keywords

Clear cell ovarian carcinoma; Endometrioid ovarian carcinoma; Lynch Syndrome; Microsatellite instability; Mismatch repair; Ovarian cancer

Indexed keywords

MISMATCH REPAIR PROTEIN PMS2; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6;

ADULT; ARTICLE; CANCER PATIENT; CLEAR CELL CARCINOMA; CLEAR CELL OVARIAN CARCINOMA; DISEASE ASSOCIATION; DNA METHYLATION; ENDOMETRIOID OVARIAN CARCINOMA; FEMALE; GERMLINE MUTATION; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MISMATCH REPAIR; OVARY CARCINOMA; PREVALENCE; PRIMARY TUMOR; PROTEIN EXPRESSION; RISK ASSESSMENT; TISSUE MICROARRAY; ADENOCARCINOMA; AGED; ENDOMETRIOID CARCINOMA; GENETICS; MIDDLE AGED; MULTIPLE CANCER; OVARY TUMOR; RETROSPECTIVE STUDY; VERY ELDERLY;

ADENOCARCINOMA, CLEAR CELL; ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, ENDOMETRIOID; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA MISMATCH REPAIR; FEMALE; HUMANS; MIDDLE AGED; NEOPLASMS, MULTIPLE PRIMARY; OVARIAN NEOPLASMS; RETROSPECTIVE STUDIES;

EID: 84907976636     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2014.07.100     Document Type: Article

References (38)

1. A.K. Folkins, E.A. Jarboe, M.H. Roh, and C.P. Crum Precursors to pelvic serous carcinoma and their clinical implications Gynecol Oncol 113 3 Jun 2009 391 396
2. M.C. King, J.H. Marks, and J.B. Mandell New York Breast Cancer Study Group. Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2 Science 302 5645 Oct 24 2003 643 646
3. K.M. Schmeler, and K.H. Lu Gynecologic cancers associated with Lynch syndrome/HNPCC Clin Transl Oncol 10 6 Jun 2008 313 317
4. J.J. Koornstra, M.J. Mourits, R.H. Sijmons, A.M. Leliveld, H. Hollema, and J.H. Kleibeuker Management of extracolonic tumours in patients with Lynch syndrome Lancet Oncol 10 4 Apr 2009 400 408
5. P. Watson, H.F. Vasen, J.P. Mecklin, I. Bernstein, M. Aarnio, and H.J. Järvinen The risk of extra-colonic, extra-endometrial cancer in the Lynch syndrome Int J Cancer 123 2 Jul 15 2008 444 449
6. H.T. Lynch, M.J. Casey, C.L. Snyder, C. Bewtra, J.F. Lynch, and M. Butts Hereditary ovarian carcinoma: heterogeneity, molecular genetics, pathology, and management Mol Oncol 3 2 Apr 2009 97 137
7. M. Aarnio, R. Sankila, E. Pukkala, R. Salovaara, L.A. Aaltonen, and A. de la Chapelle Cancer risk in mutation carriers of DNA-mismatch-repair genes Int J Cancer 81 2 Apr 12 1999 214 218
8. Z. Ketabi, K. Bartuma, I. Bernstein, S. Malander, H. Grönberg, and E. Björck Ovarian cancer linked to Lynch syndrome typically presents as early-onset, non-serous epithelial tumors Gynecol Oncol 121 3 Jun 1 2011 462 465
9. F.I. Lu, C.B. Gilks, A.M. Mulligan, P. Ryan, G. Allo, and K. Sy Prevalence of loss of expression of DNA mismatch repair proteins in primary epithelial ovarian tumors Int J Gynecol Pathol 31 6 Nov 2012 524 531
10. T. Pal, J. Permuth-Wey, A. Kumar, and T.A. Sellers Systematic review and meta-analysis of ovarian cancers: estimation of microsatellite-high frequency and characterization of mismatch repair deficient tumor histology Clin Cancer Res 14 21 Nov 1 2008 6847 6854
11. M.A. Murphy, and N. Wentzensen Frequency of mismatch repair deficiency in ovarian cancer: a systematic review Int J Cancer 129 8 Oct 15 2011 1914 1922
12. E. Gras, L. Catasus, R. Argüelles, G. Moreno-Bueno, J. Palacios, and C. Gamallo Microsatellite instability, MLH-1 promoter hypermethylation, and frameshift mutations at coding mononucleotide repeat microsatellites in ovarian tumors Cancer 92 11 Dec 1 2001 2829 2836
13. K.Q. Cai, C. Albarracin, D. Rosen, R. Zhong, W. Zheng, and R. Luthra Microsatellite instability and alteration of the expression of hMLH1 and hMSH2 in ovarian clear cell carcinoma Hum Pathol 35 5 May 2004 552 559
14. J. Liu, C.T. Albarracin, K.H. Chang, J.A. Thompson-Lanza, W. Zheng, and D.M. Gershenson Microsatellite instability and expression of hMLH1 and hMSH2 proteins in ovarian endometrioid cancer Mod Pathol 17 1 Jan 2004 75 80
15. H. Ueda, Y. Watanabe, H. Nakai, H. Hemmi, M. Koi, and H. Hoshiai Microsatellite status and immunohistochemical features of ovarian clear-cell carcinoma Anticancer Res 25 4 Jul-Aug 2005 2785 2788
16. H.T. Lynch, P.M. Lynch, S.J. Lanspa, C.L. Snyder, J.F. Lynch, and C.R. Boland Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications Clin Genet 76 1 Jul 2009 1 18
17. G.M. Li Mechanisms and functions of DNA mismatch repair Cell Res 18 1 Jan 2008 85 98
18. P. Peltomäki, and H. Vasen Mutations associated with HNPCC predisposition - Update of ICG-HNPCC/INSiGHT mutation database Dis Markers 20 4-5 2004 269 276
19. V. Piñol, A. Castells, M. Andreu, S. Castellví-Bel, C. Alenda, and X. Llor Gastrointestinal Oncology Group of the Spanish Gastroenterological Association. Accuracy of revised Bethesda guidelines, microsatellite instability, and immunohistochemistry for the identification of patients with hereditary nonpolyposis colorectal cancer JAMA 293 16 Apr 27 2005 1986 1994
20. L.M. Baudhuin, L.J. Burgart, O. Leontovich, and S.N. Thibodeau Use of microsatellite instability and immunohistochemistry testing for the identification of individuals at risk for Lynch syndrome Fam Cancer 4 3 2005 255 265
21. V.A. Marcus, L. Madlensky, R. Gryfe, H. Kim, K. So, and A. Millar Immunohistochemistry for hMLH1 and hMSH2: a practical test for DNA mismatch repair-deficient tumors Am J Surg Pathol 23 10 Oct 1999 1248 1255
22. N.M. Lindor, L.J. Burgart, O. Leontovich, R.M. Goldberg, J.M. Cunningham, and D.J. Sargent Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors J Clin Oncol 20 4 Feb 15 2002 1043 1048
23. J.M. Lancaster, C.B. Powell, N.D. Kauff, I. Cass, L.M. Chen, and K.H. Lu Society of Gynecologic Oncologists Education Committee Society of Gynecologic Oncologists Education Committee statement on risk assessment for inherited gynecologic cancer predispositions Gynecol Oncol 107 2 Nov 2007 159 162
24. K.R. Lee, F.A. Tavassoli, and J. Prat Pathology and Genetics of Tumours of the Breast and Female Genital Organs F.A. Tavassoli, P. Devilee, Surface Epithelial-Stromal Tumors 2003 IARC Press Lyon 117 145
25. S. Malander, E. Rambech, U. Kristoffersson, B. Halvarsson, M. Ridderheim, and A. Borg The contribution of the hereditary nonpolyposis colorectal cancer syndrome to the development of ovarian cancer Gynecol Oncol 101 2 May 2006 238 243
26. K.C. Jensen, M.R. Mariappan, G.V. Putcha, A. Husain, N. Chun, and J.M. Ford Microsatellite instability and mismatch repair protein defects in ovarian epithelial neoplasms in patients 50 years of age and younger Am J Surg Pathol 32 7 Jul 2008 1029 1037
27. K. Domanska, S. Malander, A. Måsbäck, and M. Nilbert Ovarian cancer at young age: the contribution of mismatch-repair defects in a population-based series of epithelial ovarian cancer before age 40 Int J Gynecol Cancer 17 4 Jul-Aug 2007 789 793
28. D.G. Rosen, K.Q. Cai, R. Luthra, and J. Liu Immunohistochemical staining of hMLH1 and hMSH2 reflects microsatellite instability status in ovarian carcinoma Mod Pathol 19 11 Nov 2006 1414 1420
29. N.P. Zauber, T.R. Denehy, R.R. Taylor, E.H. Ongcapin, S.P. Marotta, and M. Sabbath-Solitare Microsatellite instability and DNA methylation of endometrial tumors and clinical features in young women compared with older women Int J Gynecol Cancer 20 9 Dec 2010 1549 1556
30. A.K. Sood, R. Holmes, M.J. Hendrix, and R.E. Buller Application of the National Cancer Institute international criteria for determination of microsatellite instability in ovarian cancer Cancer Res 61 11 Jun 1 2001 4371 4374
31. J.P. Geisler, M.J. Goodheart, A.K. Sood, R.J. Holmes, M.A. Hatterman-Zogg, and R.E. Buller Mismatch repair gene expression defects contribute to microsatellite instability in ovarian carcinoma Cancer 98 10 Nov 15 2003 2199 2206
32. G. Singer, T. Kallinowski, A. Hartmann, W. Dietmaier, P.J. Wild, and P. Schraml Different types of microsatellite instability in ovarian carcinoma Int J Cancer 112 4 Nov 20 2004 643 646
33. L.A. Loeb Microsatellite instability: marker of a mutator phenotype in cancer Cancer Res 54 19 Oct 1 1994 5059 5063
34. C.R. Boland, S.N. Thibodeau, S.R. Hamilton, D. Sidransky, J.R. Eshleman, and R.W. Burt A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer Cancer Res 58 22 Nov 15 1998 5248 5257
35. A.K. Folkins, and T.A. Longacre Hereditary gynaecological malignancies: advances in screening and treatment Histopathology 62 1 Jan 2013 2 30
36. K.M. Schmeler, H.T. Lynch, L.M. Chen, M.F. Munsell, P.T. Soliman, and M.B. Clark Prophylactic surgery to reduce the risk of gynecologic cancers in the Lynch syndrome N Engl J Med 354 3 Jan 19 2006 261 269
37. G. Zanetta, S. Chiari, S. Rota, G. Bratina, A. Maneo, and V. Torri Conservative surgery for stage I ovarian carcinoma in women of childbearing age Br J Obstet Gynaecol 104 9 Sep 1997 1030 1035
38. A. Aysal, A. Karnezis, I. Medhi, J.P. Grenert, C.J. Zaloudek, and J.T. Rabban Ovarian endometrioid adenocarcinoma: incidence and clinical significance of the morphologic and immunohistochemical markers of mismatch repair protein defects and tumor microsatellite instability Am J Surg Pathol 36 2 Feb 2012 163 172