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Volumn 24, Issue 21, 2014, Pages 4931-4938
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Discovery of substituted 4-aminoquinazolines as selective Toll-like receptor 4 ligands
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Author keywords
4 Aminoquinazolines; Innate immune response; MD 2; NF B activation; Toll like receptor 4
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Indexed keywords
4 AMINOQUINAZOLINE DERIVATIVE;
B7 ANTIGEN;
BROMINE;
CD14 ANTIGEN;
CD83 ANTIGEN;
CHLORINE;
IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;
IMMUNOMODULATING AGENT;
INTERLEUKIN 6;
INTERLEUKIN 8;
PROTEIN MD 2;
QUINAZOLINE DERIVATIVE;
TOLL LIKE RECEPTOR 4;
TOLL LIKE RECEPTOR AGONIST;
UNCLASSIFIED DRUG;
4-AMINOQUINAZOLINE;
LIGAND;
TOLL LIKE RECEPTOR;
ANIMAL TISSUE;
ANTIGEN PRESENTING CELL;
ARTICLE;
BONE MARROW DERIVED DENDRITIC CELL;
BONE MARROW DERIVED MACROPHAGE;
CELL VIABILITY;
COMPLEX FORMATION;
CRYSTAL STRUCTURE;
HIGH THROUGHPUT SCREENING;
HUMAN;
HUMAN TISSUE;
HYDROGEN BOND;
HYDROPHOBICITY;
INTERFERON PRODUCTION;
MOUSE;
NONHUMAN;
PERIPHERAL BLOOD MONONUCLEAR CELL;
SIGNAL TRANSDUCTION;
SPLEEN CELL;
STRUCTURE ACTIVITY RELATION;
ANIMAL;
CHEMICAL STRUCTURE;
CHEMISTRY;
CYTOLOGY;
INNATE IMMUNITY;
METABOLISM;
MONONUCLEAR CELL;
ANIMALS;
HIGH-THROUGHPUT SCREENING ASSAYS;
HUMANS;
IMMUNITY, INNATE;
INTERLEUKIN-6;
INTERLEUKIN-8;
LEUKOCYTES, MONONUCLEAR;
LIGANDS;
MICE;
MODELS, MOLECULAR;
MOLECULAR STRUCTURE;
NF-KAPPA B;
QUINAZOLINES;
SIGNAL TRANSDUCTION;
STRUCTURE-ACTIVITY RELATIONSHIP;
TOLL-LIKE RECEPTOR 4;
TOLL-LIKE RECEPTORS;
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EID: 84907970133
PISSN: 0960894X
EISSN: 14643405
Source Type: Journal
DOI: 10.1016/j.bmcl.2014.09.039 Document Type: Article |
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Times cited : (21)
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References (21)
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