Analysis of high-throughput screening assays using cluster enrichment

Statistics in Medicine

Volumn 31, Issue 30, 2012, Pages 4175-4189

  Pu, Minya ^a   Hayashi, Tomoko ^a   Cottam, Howard ^a   Mulvaney, Joseph ^b   Arkin, Michelle ^b   Corr, Maripat ^a   Carson, Dennis ^a   Messer, Karen ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cluster analysis; Fingerprint descriptors; High throughput screening; Hit selection; HTS hit selection; Murcko fragments; Top X

Indexed keywords

LIPOPOLYSACCHARIDE; PHOSPHATE BUFFERED SALINE;

ALGORITHM; ARTICLE; CELL ASSAY; CLUSTER ANALYSIS; COMPUTER PROGRAM; FALSE POSITIVE RESULT; GENE EXPRESSION; HIGH THROUGHPUT SCREENING; HUMAN; KOLMOGOROV SMIRNOV TEST; PROSPECTIVE STUDY; QUALITY CONTROL; ROBOTICS; SCORING SYSTEM; SENSITIVITY AND SPECIFICITY; STATISTICAL ANALYSIS;

ANTINEOPLASTIC AGENTS; CLUSTER ANALYSIS; DATA INTERPRETATION, STATISTICAL; DRUG DISCOVERY; FALSE POSITIVE REACTIONS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; ODDS RATIO; PROSPECTIVE STUDIES; RESEARCH DESIGN;

EID: 84870875356     PISSN: 02776715     EISSN: 10970258     Source Type: Journal    
DOI: 10.1002/sim.5455     Document Type: Article

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