Euodenine A: A small-molecule agonist of human TLR4

Journal of Medicinal Chemistry

Volumn 57, Issue 4, 2014, Pages 1252-1275

  Neve, Juliette E ^a   Wijesekera, Hasanthi P ^a   Duffy, Sandra ^a   Jenkins, Ian D ^a   Ripper, Justin A ^a   Teague, Simon J ^b   Campitelli, Marc ^a   Garavelas, Agatha ^a   Nikolakopoulos, George ^a   Le, Phuc V ^a   De A Leone, Priscila ^a   Pham, Ngoc B ^a   Shelton, Philip ^b   Fraser, Neil ^b   Carroll, Anthony R ^a   Avery, Vicky M ^a   McCrae, Christopher ^c   Williams, Nicola ^b   Quinn, Ronald J ^a  

^a GRIFFITH UNIVERSITY   (Australia)

^b ASTRAZENECA   (United Kingdom)

^c ASTRAZENECA R AND D   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOBUTANE; EUODENINE A; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 5; INTERLEUKIN 8; NATURAL PRODUCT; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG POTENCY; DRUG SYNTHESIS; EUODIA ASTERIDULA; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOMODULATION; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PLANT LEAF; RUTACEAE; STRUCTURE ACTIVITY RELATION; TH2 CELL;

ANIMALS; CYTOKINES; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; HUMANS; QUINOLONES; STRUCTURE-ACTIVITY RELATIONSHIP; TOLL-LIKE RECEPTOR 4;

EID: 84896872957     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm401321v     Document Type: Article

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