메뉴 건너뛰기




Volumn 19, Issue 9, 2013, Pages 2584-2591

Characteristics of lung cancers harboring NRAS mutations

(23)  Ohashi, Kadoaki a   Sequist, Lecia V e,f   Arcila, Maria E g   Lovly, Christine M a   Chen, Xi b   Rudin, Charles M h   Moran, Teresa i   Camidge, David Ross j   Vnencak Jones, Cindy L c   Berry, Lynne b   Pan, Yumei a   Sasaki, Hidefumi k   Engelman, Jeffrey A e,f   Garon, Edward B l   Dubinett, Steven M l   Franklin, Wilbur A j   Riely, Gregory J g   Sos, Martin L m,n,o   Kris, Mark G g   Dias Santagata, Dora d   more..


Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; CRIZOTINIB; ERLOTINIB; K RAS PROTEIN; LINSITINIB; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; SELUMETINIB; SOMATOMEDIN C RECEPTOR; TRAMETINIB; VASCULOTROPIN;

EID: 84877097856     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-12-3173     Document Type: Article
Times cited : (126)

References (47)
  • 5
    • 75249087060 scopus 로고    scopus 로고
    • Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): An open label, randomised phase 3 trial
    • Mitsudomi T, Morita S, Yatabe Y, Negoro S, Okamoto I, Tsurutani J, et al. Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial. Lancet Oncol 2010;11:121-8.
    • (2010) Lancet Oncol , vol.11 , pp. 121-128
    • Mitsudomi, T.1    Morita, S.2    Yatabe, Y.3    Negoro, S.4    Okamoto, I.5    Tsurutani, J.6
  • 8
    • 80053386829 scopus 로고    scopus 로고
    • Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: A retrospective analysis
    • Shaw AT, Yeap BY, Solomon BJ, Riely GJ, Gainor J, Engelman JA, et al. Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis. Lancet Oncol 2011;12:1004-12.
    • (2011) Lancet Oncol , vol.12 , pp. 1004-1012
    • Shaw, A.T.1    Yeap, B.Y.2    Solomon, B.J.3    Riely, G.J.4    Gainor, J.5    Engelman, J.A.6
  • 9
    • 79956316170 scopus 로고    scopus 로고
    • Clinical characteristics of patients with lung adenocarcinomas harboring BRAF mutations
    • Paik PK, Arcila ME, Fara M, Sima CS, Miller VA, Kris MG, et al. Clinical characteristics of patients with lung adenocarcinomas harboring BRAF mutations. J Clin Oncol 2011;29:2046-51.
    • (2011) J Clin Oncol , vol.29 , pp. 2046-2051
    • Paik, P.K.1    Arcila, M.E.2    Fara, M.3    Sima, C.S.4    Miller, V.A.5    Kris, M.G.6
  • 10
    • 82355191818 scopus 로고    scopus 로고
    • Implementing multiplexed genotyping of non-small-cell lung cancers into routine clinical practice
    • Sequist LV, Heist RS, Shaw AT, Fidias P, Rosovsky R, Temel JS, et al. Implementing multiplexed genotyping of non-small-cell lung cancers into routine clinical practice. Ann Oncol 2011;22:2616-24.
    • (2011) Ann Oncol , vol.22 , pp. 2616-2624
    • Sequist, L.V.1    Heist, R.S.2    Shaw, A.T.3    Fidias, P.4    Rosovsky, R.5    Temel, J.S.6
  • 12
    • 84655167862 scopus 로고    scopus 로고
    • Lung adenocarcinomas with HER2-activating mutations are associated with distinct clinical features and HER2/EGFR copy number gains
    • Li C, Sun Y, Fang R, Han X, Luo X, Wang R, et al. Lung adenocarcinomas with HER2-activating mutations are associated with distinct clinical features and HER2/EGFR copy number gains. J Thorac Oncol 2012;7:85-9.
    • (2012) J Thorac Oncol , vol.7 , pp. 85-89
    • Li, C.1    Sun, Y.2    Fang, R.3    Han, X.4    Luo, X.5    Wang, R.6
  • 14
    • 84856823963 scopus 로고    scopus 로고
    • Coexistence of PIK3CA and other oncogene mutations in lung adenocarcinoma-rationale for comprehensive mutation profiling
    • Chaft JE, Arcila ME, Paik PK, Lau C, Riely GJ, Pietanza MC, et al. Coexistence of PIK3CA and other oncogene mutations in lung adenocarcinoma- rationale for comprehensive mutation profiling. Mol Cancer Ther 2012;11:485-91.
    • (2012) Mol Cancer Ther , vol.11 , pp. 485-491
    • Chaft, J.E.1    Arcila, M.E.2    Paik, P.K.3    Lau, C.4    Riely, G.J.5    Pietanza, M.C.6
  • 16
    • 48649107410 scopus 로고    scopus 로고
    • Novel MEK1 mutation identified by mutational analysis of epidermal growth factor receptor signaling pathway genes in lung adenocarcinoma
    • Marks JL, Gong Y, Chitale D, Golas B, McLellan MD, Kasai Y, et al. Novel MEK1 mutation identified by mutational analysis of epidermal growth factor receptor signaling pathway genes in lung adenocarcinoma. Cancer Res 2008;68:5524-8.
    • (2008) Cancer Res , vol.68 , pp. 5524-5528
    • Marks, J.L.1    Gong, Y.2    Chitale, D.3    Golas, B.4    McLellan, M.D.5    Kasai, Y.6
  • 17
    • 82355161909 scopus 로고    scopus 로고
    • Spectrum of oncogenic driver mutations in lung adenocarcinomas from East Asian never smokers
    • Li C, Fang R, Sun Y, Han X, Li F, Gao B, et al. Spectrum of oncogenic driver mutations in lung adenocarcinomas from East Asian never smokers. PLoS One 2011;6:e28204.
    • (2011) PLoS One , vol.6
    • Li, C.1    Fang, R.2    Sun, Y.3    Han, X.4    Li, F.5    Gao, B.6
  • 21
    • 84862776857 scopus 로고    scopus 로고
    • Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies
    • Lipson D, Capelletti M, Yelensky R, Otto G, Parker A, Jarosz M, et al. Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies. Nat Med 2012;18:382-4.
    • (2012) Nat Med , vol.18 , pp. 382-384
    • Lipson, D.1    Capelletti, M.2    Yelensky, R.3    Otto, G.4    Parker, A.5    Jarosz, M.6
  • 23
    • 79251490374 scopus 로고    scopus 로고
    • New driver mutations in non-small-cell lung cancer
    • Pao W, Girard N. New driver mutations in non-small-cell lung cancer. Lancet Oncol 2011;12:175-80.
    • (2011) Lancet Oncol , vol.12 , pp. 175-180
    • Pao, W.1    Girard, N.2
  • 25
    • 0037542854 scopus 로고    scopus 로고
    • Ras proteins: Different signals from different locations
    • DOI 10.1038/nrm1105
    • Hancock JF. Ras proteins: different signals from different locations. Nat Rev Mol Cell Biol 2003;4:373-84. (Pubitemid 36565569)
    • (2003) Nature Reviews Molecular Cell Biology , vol.4 , Issue.5 , pp. 373-384
    • Hancock, J.F.1
  • 30
    • 42149192000 scopus 로고    scopus 로고
    • Activated Kras, but not Hras or Nras, may initiate tumors of endodermal origin via stem cell expansion
    • Quinlan MP, Quatela SE, Philips MR, Settleman J. Activated Kras, but not Hras or Nras, may initiate tumors of endodermal origin via stem cell expansion. Mol Cell Biol 2008;28:2659-74.
    • (2008) Mol Cell Biol , vol.28 , pp. 2659-2674
    • Quinlan, M.P.1    Quatela, S.E.2    Philips, M.R.3    Settleman, J.4
  • 32
    • 77954566882 scopus 로고    scopus 로고
    • Rapid targeted mutational analysis of human tumours: A clinical platform to guide personalized cancer medicine
    • Dias-Santagata D, Akhavanfard S, David SS, Vernovsky K, Kuhlmann G, Boisvert SL, et al. Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine. EMBO Mol Med 2010;2:146-58.
    • (2010) EMBO Mol Med , vol.2 , pp. 146-158
    • Dias-Santagata, D.1    Akhavanfard, S.2    David, S.S.3    Vernovsky, K.4    Kuhlmann, G.5    Boisvert, S.L.6
  • 33
    • 78651079558 scopus 로고    scopus 로고
    • A platform for rapid detection of multiple oncogenic mutations with relevance to targeted therapy in non-small-cell lung cancer
    • Su Z, Dias-Santagata D, Duke M, Hutchinson K, Lin YL, Borger DR, et al. A platform for rapid detection of multiple oncogenic mutations with relevance to targeted therapy in non-small-cell lung cancer. J Mol Diagn 2011;13:74-84.
    • (2011) J Mol Diagn , vol.13 , pp. 74-84
    • Su, Z.1    Dias-Santagata, D.2    Duke, M.3    Hutchinson, K.4    Lin, Y.L.5    Borger, D.R.6
  • 34
    • 70350218696 scopus 로고    scopus 로고
    • High expression levels of total IGF-1R and sensitivity of NSCLC cells in vitro to an anti-IGF-1R antibody (R1507)
    • Gong Y, Yao E, Shen R, Goel A, Arcila M, Teruya-Feldstein J, et al. High expression levels of total IGF-1R and sensitivity of NSCLC cells in vitro to an anti-IGF-1R antibody (R1507). PLoS One 2009;4:e7273.
    • (2009) PLoS One , vol.4
    • Gong, Y.1    Yao, E.2    Shen, R.3    Goel, A.4    Arcila, M.5    Teruya-Feldstein, J.6
  • 35
  • 37
    • 53249145767 scopus 로고    scopus 로고
    • Frequency and distinctive spectrum of KRAS mutations in never smokers with lung adenocarcinoma
    • Riely GJ, Kris MG, Rosenbaum D, Marks J, Li A, Chitale DA, et al. Frequency and distinctive spectrum of KRAS mutations in never smokers with lung adenocarcinoma. Clin Cancer Res 2008;14:5731-4.
    • (2008) Clin Cancer Res , vol.14 , pp. 5731-5734
    • Riely, G.J.1    Kris, M.G.2    Rosenbaum, D.3    Marks, J.4    Li, A.5    Chitale, D.A.6
  • 39
    • 84872853570 scopus 로고    scopus 로고
    • Oncogenic and wild-type Ras play divergent roles in the regulation of mitogen-activated protein kinase signaling
    • Young A, Lou D, McCormick F. Oncogenic and wild-type Ras play divergent roles in the regulation of mitogen-activated protein kinase signaling. Cancer Discov 2013;3:112-23.
    • (2013) Cancer Discov , vol.3 , pp. 112-123
    • Young, A.1    Lou, D.2    McCormick, F.3
  • 40
    • 84869447282 scopus 로고    scopus 로고
    • Sos-mediated cross-activation of wild-type Ras by oncogenic Ras is essential for tumorigenesis
    • Jeng HH, Taylor LJ, Bar-Sagi D. Sos-mediated cross-activation of wild-type Ras by oncogenic Ras is essential for tumorigenesis. Nat Commun 2012;3:1168.
    • (2012) Nat Commun , vol.3 , pp. 1168
    • Jeng, H.H.1    Taylor, L.J.2    Bar-Sagi, D.3
  • 41
    • 84861147473 scopus 로고    scopus 로고
    • A comprehensive survey of ras mutations in cancer
    • Prior IA, Lewis PD, Mattos C. A comprehensive survey of ras mutations in cancer. Cancer Res 2012;72:2457-67.
    • (2012) Cancer Res , vol.72 , pp. 2457-2467
    • Prior, I.A.1    Lewis, P.D.2    Mattos, C.3
  • 42
    • 0034745389 scopus 로고    scopus 로고
    • Patterns of p53G->T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke
    • Hainaut P, Pfeifer GP. Patterns of p53 G->T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke. Carcinogenesis 2001;22:367-74. (Pubitemid 32203813)
    • (2001) Carcinogenesis , vol.22 , Issue.3 , pp. 367-374
    • Hainaut, P.1    Pfeifer, G.P.2
  • 43
    • 0029077597 scopus 로고
    • N-ras mutation in 7,12-dimethylbenz[a]anthracene (DMBA)-induced erythroleukemia in Long-Evans rats
    • Osaka M, Matsuo S, Koh T, Liang P, Kinoshita H, Maeda S, et al. N-ras mutation in 7,12-dimethylbenz[a]anthracene (DMBA)-induced erythroleukemia in Long-Evans rats. Cancer Lett 1995;91:25-31.
    • (1995) Cancer Lett , vol.91 , pp. 25-31
    • Osaka, M.1    Matsuo, S.2    Koh, T.3    Liang, P.4    Kinoshita, H.5    Maeda, S.6
  • 45
    • 70449995469 scopus 로고    scopus 로고
    • Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer
    • Sos ML, Fischer S, Ullrich R, Peifer M, Heuckmann JM, Koker M, et al. Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer. Proc Natl Acad Sci U S A 2009;106:18351-6.
    • (2009) Proc Natl Acad Sci U S a , vol.106 , pp. 18351-18356
    • Sos, M.L.1    Fischer, S.2    Ullrich, R.3    Peifer, M.4    Heuckmann, J.M.5    Koker, M.6
  • 47
    • 67651006061 scopus 로고    scopus 로고
    • Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions
    • Sos ML, Michel K, Zander T, Weiss J, Frommolt P, Peifer M, et al. Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions. J Clin Invest 2009;119:1727-40.
    • (2009) J Clin Invest , vol.119 , pp. 1727-1740
    • Sos, M.L.1    Michel, K.2    Zander, T.3    Weiss, J.4    Frommolt, P.5    Peifer, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.