Iron upregulates melanogenesis in cultured retinal pigment epithelial cells

Experimental Eye Research

Volumn 128, Issue , 2014, Pages 92-101

  Wolkow, Natalie ^a   Li, Yafeng ^a   Maminishkis, Arvydas ^b   Song, Ying ^a   Alekseev, Oleg ^a   Iacovelli, Jared ^a,c   Song, Delu ^a   Lee, Jennifer C ^a,d   Dunaief, Joshua L ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NATIONAL EYE INSTITUTE   (United States)

^c SCHEPENS EYE RESEARCH INSTITUTE   (United States)

^d SALUS UNIVERSITY   (United States)

Author keywords

ARPE 19 cells; FAC; HfRPE cells; Human fetal retinal pigment epithelial cells; Iron; LEF 1; Melanosome; MITF; Retinal pigment epithelium

Indexed keywords

DOPACHROME TAUTOMERASE; FERRIC AMMONIUM CITRATE; HERMANSKY PUDLAK SYNDROME 3 PROTEIN; IRON; LYMPHOID ENHANCER FACTOR 1; MELANIN; MELANOCYTE PROTEIN PMEL 17; MESSENGER RNA; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; MONOPHENOL MONOOXYGENASE; PROTEIN; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR OTX2; TRANSCRIPTION FACTOR PAX3; TRANSCRIPTION FACTOR SOX10; TRANSCRIPTION FACTOR SOX9; TRANSFERRIN RECEPTOR; TYROSINASE RELATED PROTEIN 1; UNCLASSIFIED DRUG; CARRIER PROTEIN; DOPACHROME ISOMERASE; FERRIC ION; HPS3 PROTEIN, HUMAN; ISOMERASE; MEMBRANE PROTEIN; OXIDOREDUCTASE; PMEL PROTEIN, HUMAN; QUATERNARY AMMONIUM DERIVATIVE; TYRP1 PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; FETUS; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IRON THERAPY; MELANOGENESIS; MELANOSOME; PIGMENT CELL; PIGMENTATION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; BIOSYNTHESIS; CELL CULTURE; DONOR; DRUG EFFECTS; EMBRYOLOGY; GENETICS; GESTATIONAL AGE; METABOLISM; PHYSIOLOGY; PIGMENT EPITHELIUM; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

BLOTTING, WESTERN; CARRIER PROTEINS; CELLS, CULTURED; FERRIC COMPOUNDS; GESTATIONAL AGE; GP100 MELANOMA ANTIGEN; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; MELANINS; MELANOSOMES; MEMBRANE GLYCOPROTEINS; MONOPHENOL MONOOXYGENASE; OXIDOREDUCTASES; QUATERNARY AMMONIUM COMPOUNDS; REAL-TIME POLYMERASE CHAIN REACTION; RETINAL PIGMENT EPITHELIUM; RNA, MESSENGER; TISSUE DONORS; UP-REGULATION;

EID: 84907959159     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2014.09.010     Document Type: Article

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