Experimental models for study of retinal pigment epithelial physiology and pathophysiology

Journal of Visualized Experiments

Volumn , Issue 45, 2010, Pages

  Maminishkis, Arvydas ^a   Miller, Sheldon S ^a  

^a NATIONAL EYE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 80055115628     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/2032     Document Type: Article

References (15)

1. Bharti, K., Miller, S.S., & Arnheiter, H. The new paradigm: Retinal pigment epithelium cells generated from embryonic stem cells or induced pluripotent cells. Pigment Cell & Melanoma Research (forthcoming).
2. Strunnikova, N.V., Maminishkis, A., Barb, J.J., Wang, F., Zhi, C., Sergeev, Y., Chen, W., Edwards, A.O., Stambolian, D., Abecasis, G., Swaroop, A., Munson, P.J., & Miller, S.S. Transcriptome analysis and molecular signature of human retinal pigment epithelium. Hum Mol Genet 19 (12), 2468-86 (2010).
3. Miller, S.S., Maminishkis, Li, R., & J. Adijanto. Retinal pigment epithelium: cytokine modulation of epithelial physiology. in Encyclopedia of the Eye, Chapter 184: Phototransduction: RPE transport Retina Phototransduction: RPE transport. Elsevier, 2540 (2010).
4. Bryant, D. M. & Mostov, K. E. From cells to organs: Building polarized tissue. Nature Reviews. Molecular Cell Biology 9(11): 887-901 (2008).
5. Maminishkis, A., Chen, S., Jalickee, S., Banzon, T., Shi, G., Wang, F.E., Ehalt, T., Hammer, J.A. & Miller, S.S. Confluent monolayers of cultured human fetal retinal pigment epithelium exhibit morphology and physiology of native tissue. Invest Ophthalmol Vis Sci 47, 3612-3624 (2006).
6. Shi, G., Maminishkis, A., Banzon, T., Jalickee, S., Li, R., Hammer, J. & Miller, S.S. Control of chemokine gradients by the retinal pigment epithelium. Invest Ophthalmol Vis Sci 49, 4620-4630 (2008).
7. Economopoulou, M., Hammer, J., Wang, F.E., Fariss, R., Maminishkis, A. & Miller, S.S. Expression, localization, and function of junctional adhesion molecule-C (JAM-C) in human retinal pigment epithelium. Invest Ophthalmol Vis Sci 50(3):1454-1463 (2008).
8. Li, R., Maminishkis, A., Banzon, T., Wan, Q., Jalickee, S., Chen, S. & Miller, S.S. IFN{gamma} Regulates Retinal Pigment Epithelial Fluid Transport. Am J Physiol Cell Physiol 297: C1452-C1465 (2009).
9. Li, R., Maminishkis, A., Wang, F.E. & Miller, S.S. PDGF-C and-D induced proliferation/migration of human RPE is abolished by inflammatory cytokines. Invest Ophthalmol Vis Sci 48, 5722-5732 (2007).
10. Maminishkis, A., Jalickee, S., Blaug, S.A., Rymer, J., Yerxa, B.R., Peterson, W.M. & Miller, S.S. The P2Y(2) receptor agonist INS37217 stimulates RPE fluid transport in vitro and retinal reattachment in rat. Invest Ophthalmol Vis Sci 43, 3555-3566 (2002).
11. Wang, F.E., Zhang, C., Maminishkis, A., Dong, L., Zhi, C., Li, R., Zhao, J., Majerciak, V., Gaur, A.B., Chen, S. et al. MicroRNA-204/211 alters epithelial physiology. FASEB J 24 (2010).
12. Adijanto, J., Banzon, T., Jalickee, S., Wang, N.S. & Miller, S.S. CO2-induced ion and fluid transport in human retinal pigment epithelium. J Gen Physiol 133, 603-622 (2009).
13. Li, R., Maminishkis, A., Zahn, G., Vossmeyer, D. & Miller, S.S. Integrin alpha5beta1 mediates attachment, migration, and proliferation in human retinal pigment epithelium: relevance for proliferative retinal disease. Invest Ophthalmol Vis Sci 50, 5988-5996 (2009).
14. Peterson, W.M., Meggyesy, C., Yu, K. & Miller, S.S. Extracellular ATP activates calcium signaling, ion, and fluid transport in retinal pigment epithelium. J Neurosci 17, 2324-2337 (1997).
15. Voloboueva, L.A., Liu, J., Suh, J.H., Ames, B.N. & Miller, S.S. (R)-alpha-lipoic acid protects retinal pigment epithelial cells from oxidative damage. Invest Ophthalmol Vis Sci 46, 4302-4310 (2005).