메뉴 건너뛰기




Volumn 57, Issue , 2014, Pages 90-98

Design, synthesis, in silico and in vitro screening of 1,2,4-thiadiazole analogues as non-peptide inhibitors of beta-secretase

Author keywords

1,2,4 Thiadiazoles; Beta secretase; In vitro FRET assay; Molecular docking

Indexed keywords

1 (3' ACETYLPHENYL) 3 (3'' (ETHYLTHIO)1'',2'',4'' THIADIAZOL 5'' YL)UREA; 1 (3' ACETYLPHENYL) 3 (3'' (METHYL)1'',2'',4'' THIADIAZOL 5'' YL)UREA; 1 (3' ACETYLPHENYL) 3 (3'' (METHYLTHIO)1'',2'',4'' THIADIAZOL 5'' YL)UREA; 1 (3' ACETYLPHENYL) 3 (3'' (PHENYL)1'',2'',4'' THIADIAZOL 5'' YL)UREA; 1 (3' CHLOROPHENYL) 3 (3'' (ETHYLTHIO)1'',2'',4'' THIADIAZOL 5'' YL)UREA; 1 (3' CHLOROPHENYL) 3 (3'' (METHYL)1'',2'',4'' THIADIAZOL 5'' YL)UREA; 1 (3' CHLOROPHENYL) 3 (3'' (METHYLTHIO)1'',2'',4'' THIADIAZOL 5'' YL)UREA; 1 (3' CHLOROPHENYL) 3 (3'' (PHENYL)1'',2'',4'' THIADIAZOL 5'' YL)UREA; 1 (3' CYANOPHENYL) 3 (3'' (ETHYLTHIO)1'',2'',4'' THIADIAZOL 5'' YL)UREA; 1 (3' CYANOPHENYL) 3 (3'' (METHYL)1'',2'',4'' THIADIAZOL 5'' YL)UREA; 1 (3' CYANOPHENYL) 3 (3'' (METHYLTHIO)1'',2'',4'' THIADIAZOL 5'' YL)UREA; 1 (3' CYANOPHENYL) 3 (3'' (PHENYL)1'',2'',4'' THIADIAZOL 5'' YL)UREA; 1 (3' METHOXYPHENYL) 3 (3'' (ETHYLTHIO)1'',2'',4'' THIADIAZOL 5'' YL)UREA; 1 (3' METHOXYPHENYL) 3 (3'' (METHYL)1'',2'',4'' THIADIAZOL 5'' YL)UREA; 1 (3' METHOXYPHENYL) 3 (3'' (METHYLTHIO)1'',2'',4'' THIADIAZOL 5'' YL)UREA; 1 (3' METHYLTHIOPHENYL) 3 (3'' (ETHYLTHIO)1'',2'',4'' THIADIAZOL 5'' YL)UREA; 1 (3' METHYLTHIOPHENYL) 3 (3'' (METHYL)1'',2'',4'' THIADIAZOL 5'' YL)UREA; 1 (3' METHYLTHIOPHENYL) 3 (3'' (METHYLTHIO)1'',2'',4'' THIADIAZOL 5'' YL)UREA; 1 (3' NITROPHENYL) 3 (3'' (ETHYLTHIO)1'',2'',4'' THIADIAZOL 5'' YL)UREA; 1 (3' NITROPHENYL) 3 (3'' (METHYL)1'',2'',4'' THIADIAZOL 5'' YL)UREA; 1 (3' NITROPHENYL) 3 (3'' (METHYLTHIO)1'',2'',4'' THIADIAZOL 5'' YL)UREA; 1,2,4 THIADIAZOLE DERIVATIVE; 3 (ETHYLTHIO) 1,2,4 THIADIAZOL 5 AMINE; 3 (METHYLTHIO) 1,2,4 THIADIAZOL 5 AMINE; 3 METHYL 1,2,4 THIADIAZOL 5 AMINE; 3 PHENYL 1,2,4 THIADIAZOL 5 AMINE; 3 PHENYL 5 (1 (4 METHYLPHENYL)SULFONYL) 1,2,4 THIADIAZOLE (3 PHENYL 5 TOSYL 1,2,4 THIADIAZOLE; 5 PHENYL 1,3,4 OXTHIAZOL 2 ONE; BETA SECRETASE INHIBITOR; UNCLASSIFIED DRUG; UNINDEXED DRUG; SECRETASE; THIADIAZOLE DERIVATIVE;

EID: 84907943570     PISSN: 00452068     EISSN: 10902120     Source Type: Journal    
DOI: 10.1016/j.bioorg.2014.09.002     Document Type: Article
Times cited : (38)

References (43)
  • 41
    • 84907923593 scopus 로고    scopus 로고
    • Schrodinger, LLC, New York, USA
    • QikProp, version 3.0, Schrodinger, LLC, New York, USA.
    • QikProp, Version 3.0


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.