Studies on the activity of three palladium(II) compounds of the form: Trans-PdL2Cl2 where L = 2-hydroxypyridine, 3-hydroxypyridine, and 4-hydroxypyridine

Journal of Inorganic Biochemistry

Volumn 101, Issue 1, 2007, Pages 30-35

  Huq, Fazlul ^a   Tayyem, Hasan ^a   Beale, Philip ^b   Yu, Jun Qing ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b ROYAL PRINCE ALFRED HOSPITAL   (Australia)

Author keywords

3 Hydroxypyridine; Antitumour activity; Cisplatin; MTT; Palladium; Transplatin

Indexed keywords

(2 HYDROXYPYRIDINE)DICHLOROPALLADIUM; BIS(3 HYDROXYPYRIDINE)DICHLOROPALLADIUM; BIS(4 HYDROXYPYRIDINE)DICHLOROPALLADIUM; CELL NUCLEUS DNA; CISPLATIN; HYDROXYL GROUP; PALLADIUM COMPLEX;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACCUMULATION; DRUG ACTIVITY; DRUG DNA BINDING; DRUG SYNTHESIS; DRUG UPTAKE; HUMAN; HUMAN CELL; OVARY CANCER; STATISTICAL SIGNIFICANCE; STEREOSPECIFICITY;

CELL LINE, TUMOR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; PALLADIUM;

EID: 33845344313     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2006.08.001     Document Type: Article

References (17)

1. Pinedo H.M., and Schornagel J.H. Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy 2 (1996), Plenum Press, New York
2. Loehrer P.J., and Einhorn L.H. Ann. Int. Med. 100 (1984) 704-713
3. Farrell N. Met. Ions Biol. Syst. 32 (1996) 603-639
4. Huq F., Daghriri H., Yu J.Q., Beale P., and Fisher K. Eur. J. Med. Chem. 39 8 (2004) 691-697
5. Huq F., Yu J.Q., Daghriri H., and Beale P. J. Inorg. Biochem. 98 (2004) 1261-1270
6. Chowdhury A., Huq F., Abdullah A., Beale P., and Fisher K. J. Inorg. Biochem. 99 5 (2005) 1098-1112
7. Berners-Price S., and Appleton T.G. The chemistry of cisplatin in aqueous solution. In: Kelland L.R., and Farrell N.P. (Eds). Platinum-Based Drugs in Cancer Therapy (2000), Humana Press, Totowa, NJ, USA 3-35
8. Huq F., Tayyem H., Abdullah A., Beale P., and Fisher K. Asian J. Chem. 18 1 (2006) 65-78
9. Kauffman G.B., and Cowan D.O. Inorg. Synth. 7 (1963) 239-245
10. Cheng H., Huq F., Beale P., and Fisher K. Eur. J. Med. Chem. 40 8 (2005) 772-781
11. Freshney R. Culture of Animal Cells: A Manual of Basic Technique (1994), Wiley Liss, New York
12. Mosmann T. J. Immunol. Methods 65 (1983) 55-63
13. Farrell N., and Kelland L.R. Cancer Res. 52 (1992) 5065-5072
14. Heptinstall J., and Rapley R. In: Rapley R. (Ed). The Nucleic Acid Protocols Handbook (2002), Humana Press, Totowa, NJ 57-60
15. Brown R. In: Kelland L.R., and Farrell N.P. (Eds). Platinum-Based Drugs in Cancer Therapy (2000), Humana Press, Totowa, NJ, USA 115-128
16. Huq F., Abdullah A., Beale P., Yu J.Q., and Zhang M. Int. J. Pure Appl. Chem. 1 2 (2006) 205-211
17. Bose R.N. Biomolecular targets for platinum antitumor drugs. Mini. Rev. Med. Chem. 2 (2002) 103-111