Imidazo [4,5f][1,10] phenanthroline derivatives as inhibitor of c-myc gene expression in A549 cells via NF-κB pathway

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 1, 2012, Pages 102-105

  Sun, Dong Dong ^a,b   Wang, Wei Zhang ^a   Mao, Jian Wen ^a   Mei, Wen Jie ^a,b   Liu, Jie ^b  

^a GUANGDONG PHARMACEUTICAL UNIVERSITY   (China)

^b JINAN UNIVERSITY   (China)

Author keywords

Anticancer; Apoptosis; Imidazo 4,5f 1,10 phenanthroline derivatives; NF B pathway

Indexed keywords

ANTINEOPLASTIC AGENT; I KAPPA B; I KAPPA B ALPHA; IMIDAZO[4,5F][1,10]PHENANTHROLINE DERIVATIVE; PHENANTHROLINE DERIVATIVE; SYNAPTOTAGMIN I; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL DEATH; CELL GROWTH; CELL PROLIFERATION; CHEMOPROPHYLAXIS; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; DRUG POTENCY; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME REPRESSION; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; IC 50; LUNG CANCER; ONCOGENE C MYC; SIGNAL TRANSDUCTION; UPREGULATION;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; FLOW CYTOMETRY; HUMANS; INHIBITORY CONCENTRATION 50; LUNG NEOPLASMS; MODELS, CHEMICAL; NECROSIS; NF-KAPPA B; PHENANTHROLINES; PROTO-ONCOGENE PROTEINS C-MYC; TETRAZOLIUM SALTS; THIAZOLES;

EID: 84655162025     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.11.063     Document Type: Article

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