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Volumn 288, Issue 25, 2013, Pages 18484-18493

Hepatitis B viral RNA directly mediates down-regulation of the tumor suppressor microRNA miR-15a/miR-16-1 in hepatocytes

Author keywords

[No Author keywords available]

Indexed keywords

DOWN-REGULATION; HBV REPLICATION; HEPATITIS B; HEPATITIS B VIRUS; HEPATOCELLULAR CARCINOMA; HEPATOCYTES; MICRORNA EXPRESSION; TUMOR SUPPRESSORS;

EID: 84880055807     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.458158     Document Type: Article
Times cited : (104)

References (38)
  • 1
    • 77949654113 scopus 로고    scopus 로고
    • Mechanisms of HBVrelated hepatocarcinogenesis
    • Neuveut, C., Wei, Y., and Buendia, M. A. (2010) Mechanisms of HBVrelated hepatocarcinogenesis. J. Hepatol. 52, 594-604
    • (2010) J. Hepatol. , vol.52 , pp. 594-604
    • Neuveut, C.1    Wei, Y.2    Buendia, M.A.3
  • 2
    • 0022341264 scopus 로고
    • The hepatitis B virus
    • DOI 10.1038/317489a0
    • Tiollais, P., Pourcel, C., and Dejean, A. (1985) The hepatitis B virus. Nature 317, 489-495 (Pubitemid 16224154)
    • (1985) Nature , vol.317 , Issue.6037 , pp. 489-495
    • Tiollais, P.1    Pourcel, C.2    Dejean, A.3
  • 4
    • 33745517203 scopus 로고    scopus 로고
    • Hepatitis B virus-related hepatocellular carcinoma: Paradigms for viral-related human carcinogenesis
    • DOI 10.1038/sj.onc.1209559, PII 1209559
    • Kremsdorf, D., Soussan, P., Paterlini-Brechot, P., and Brechot, C. (2006) Hepatitis B virus-related hepatocellular carcinoma. Paradigms for viralrelated human carcinogenesis. Oncogene 25, 3823-3833 (Pubitemid 43980478)
    • (2006) Oncogene , vol.25 , Issue.27 , pp. 3823-3833
    • Kremsdorf, D.1    Soussan, P.2    Paterlini-Brechot, P.3    Brechot, C.4
  • 5
    • 33748288087 scopus 로고    scopus 로고
    • Molecular functions and biological roles of hepatitis B virus x protein
    • DOI 10.1111/j.1349-7006.2006.00299.x
    • Tang, H., Oishi, N., Kaneko, S., and Murakami, S. (2006) Molecular functions and biological roles of hepatitis B virus X protein. Cancer Sci. 97, 977-983 (Pubitemid 44322542)
    • (2006) Cancer Science , vol.97 , Issue.10 , pp. 977-983
    • Tang, H.1    Oishi, N.2    Kaneko, S.3    Murakami, S.4
  • 6
    • 0034099208 scopus 로고    scopus 로고
    • Putative role of hepatitis B virus X protein in hepatocarcinogenesis: Effects on apoptosis, DNA repair, mitogen-activated protein kinase and JAK/STAT pathways
    • DOI 10.1046/j.1440-1746.2000.02069.x
    • Arbuthnot, P., Capovilla, A., and Kew, M. (2000) Putative role of hepatitis B virus X protein in hepatocarcinogenesis: Effects on apoptosis, DNA repair, mitogen-activated protein kinase and JAK/STAT pathways. J. Gastroenterol. Hepatol. 15, 357-368 (Pubitemid 30262201)
    • (2000) Journal of Gastroenterology and Hepatology , vol.15 , Issue.4 , pp. 357-368
    • Arbuthnot, P.1    Capovilla, A.2    Michael, K.3
  • 7
    • 8644274040 scopus 로고    scopus 로고
    • The enigmatic X gene of hepatitis B virus
    • DOI 10.1128/JVI.78.23.12725-12734.2004
    • Bouchard, M. J., and Schneider, R. J. (2004) The enigmatic X gene of hepatitis B virus. J. Virol. 78, 12725-12734 (Pubitemid 39507781)
    • (2004) Journal of Virology , vol.78 , Issue.23 , pp. 12725-12734
    • Bouchard, M.J.1    Schneider, R.J.2
  • 8
    • 33947528120 scopus 로고    scopus 로고
    • The hepatitis B virus X protein functionally interacts with CREB-binding protein/p300 in the regulation of CREB-mediated transcription
    • DOI 10.1074/jbc.M606774200
    • Cougot, D., Wu, Y., Cairo, S., Caramel, J., Renard, C. A., Lévy, L., Buendia, M. A., and Neuveut, C. (2007) The hepatitis B virus X protein functionally interacts with CREB-binding protein/p300 in the regulation of CREBmediated transcription. J. Biol. Chem. 282, 4277-4287 (Pubitemid 47100918)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.7 , pp. 4277-4287
    • Cougot, D.1    Wu, Y.2    Cairo, S.3    Caramel, J.4    Renard, C.-A.5    Levy, L.6    Buendia, M.A.7    Neuveut, C.8
  • 10
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs. Target recognition and regulatory functions
    • Bartel, D. P. (2009) MicroRNAs. Target recognition and regulatory functions. Cell 136, 215-233
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 11
    • 44649110160 scopus 로고    scopus 로고
    • Viral and Cellular MicroRNAs as Determinants of Viral Pathogenesis and Immunity
    • DOI 10.1016/j.chom.2008.05.002, PII S1931312808001509
    • Gottwein, E., and Cullen, B. R. (2008) Viral and cellular microRNAs as determinants of viral pathogenesis and immunity. Cell Host Microbe 3, 375-387 (Pubitemid 351773098)
    • (2008) Cell Host and Microbe , vol.3 , Issue.6 , pp. 375-387
    • Gottwein, E.1    Cullen, B.R.2
  • 12
    • 84866138079 scopus 로고    scopus 로고
    • Silencing of microRNA-122 enhances interferon-signaling in the liver through regulating SOCS3 promoter methylation
    • Yoshikawa, T., Takata, A., Otsuka, M., Kishikawa, T., Kojima, K., Yoshida, H., and Koike, K. (2012) Silencing of microRNA-122 enhances interferon-signaling in the liver through regulating SOCS3 promoter methylation. Sci. Rep. 2, 637
    • (2012) Sci. Rep. , vol.2 , pp. 637
    • Yoshikawa, T.1    Takata, A.2    Otsuka, M.3    Kishikawa, T.4    Kojima, K.5    Yoshida, H.6    Koike, K.7
  • 14
    • 84984539055 scopus 로고    scopus 로고
    • Role of microRNAs in hepatitis B virus replication and pathogenesis
    • Liu, W. H., Yeh, S. H., and Chen, P. J. (2011) Role of microRNAs in hepatitis B virus replication and pathogenesis. Biochim. Biophys. Acta 1809, 678-685
    • (2011) Biochim. Biophys. Acta , vol.1809 , pp. 678-685
    • Liu, W.H.1    Yeh, S.H.2    Chen, P.J.3
  • 17
    • 82655181501 scopus 로고    scopus 로고
    • A liver-specific microRNA binds to a highly conserved RNA sequence of hepatitis B virus and negatively regulates viral gene expression and replication
    • Chen, Y., Shen, A., Rider, P. J., Yu, Y., Wu, K., Mu, Y., Hao, Q., Liu, Y., Gong, H., Zhu, Y., Liu, F., and Wu, J. (2011) A liver-specific microRNA binds to a highly conserved RNA sequence of hepatitis B virus and negatively regulates viral gene expression and replication. FASEB J. 25, 4511-4521
    • (2011) FASEB J. , vol.25 , pp. 4511-4521
    • Chen, Y.1    Shen, A.2    Rider, P.J.3    Yu, Y.4    Wu, K.5    Mu, Y.6    Hao, Q.7    Liu, Y.8    Gong, H.9    Zhu, Y.10    Liu, F.11    Wu, J.12
  • 18
    • 77953727116 scopus 로고    scopus 로고
    • MicroRNA-602 regulating tumor suppressive gene RASSF1A is overexpressed in hepatitis B virus-infected liver and hepatocellular carcinoma
    • Yang, L., Ma, Z., Wang, D., Zhao, W., Chen, L., and Wang, G. (2010) MicroRNA-602 regulating tumor suppressive gene RASSF1A is overexpressed in hepatitis B virus-infected liver and hepatocellular carcinoma. Cancer Biol. Ther. 9, 803-808
    • (2010) Cancer Biol. Ther. , vol.9 , pp. 803-808
    • Yang, L.1    Ma, Z.2    Wang, D.3    Zhao, W.4    Chen, L.5    Wang, G.6
  • 19
    • 77953574309 scopus 로고    scopus 로고
    • Lethal-7 is down-regulated by the hepatitis B virus X protein and targets signal transducer and activator of transcription 3
    • Wang, Y., Lu, Y., Toh, S. T., Sung, W. K., Tan, P., Chow, P., Chung, A. Y., Jooi, L. L., and Lee, C. G. (2010) Lethal-7 is down-regulated by the hepatitis B virus X protein and targets signal transducer and activator of transcription 3. J. Hepatol. 53, 57-66
    • (2010) J. Hepatol. , vol.53 , pp. 57-66
    • Wang, Y.1    Lu, Y.2    Toh, S.T.3    Sung, W.K.4    Tan, P.5    Chow, P.6    Chung, A.Y.7    Jooi, L.L.8    Lee, C.G.9
  • 20
    • 79959702659 scopus 로고    scopus 로고
    • Hepatitis B virus X protein downregulates expression of the miR-16 family in malignant hepatocytes in vitro
    • Wu, G., Yu, F., Xiao, Z., Xu, K., Xu, J., Tang, W., Wang, J., and Song, E. (2011) Hepatitis B virus X protein downregulates expression of the miR-16 family in malignant hepatocytes in vitro. Br. J. Cancer 105, 146-153
    • (2011) Br. J. Cancer , vol.105 , pp. 146-153
    • Wu, G.1    Yu, F.2    Xiao, Z.3    Xu, K.4    Xu, J.5    Tang, W.6    Wang, J.7    Song, E.8
  • 21
    • 0034688143 scopus 로고    scopus 로고
    • Transcriptional repression of the human p53 gene by hepatitis B viral X protein
    • Lee, S. G., and Rho, H. M. (2000) Transcriptional repression of the human p53 gene by hepatitis B viral X protein. Oncogene 19, 468-471 (Pubitemid 30077349)
    • (2000) Oncogene , vol.19 , Issue.3 , pp. 468-471
    • Lee, S.G.1    Rho, H.M.2
  • 25
    • 77953798171 scopus 로고    scopus 로고
    • Down-regulation of a host microRNA by a Herpesvirus saimiri noncoding RNA
    • Cazalla, D., Yario, T., and Steitz, J. A. (2010) Down-regulation of a host microRNA by a Herpesvirus saimiri noncoding RNA. Science 328, 1563-1566
    • (2010) Science , vol.328 , pp. 1563-1566
    • Cazalla, D.1    Yario, T.2    Steitz, J.A.3
  • 26
    • 84873852453 scopus 로고    scopus 로고
    • HBV mRNAs-mediated miR-122 inhibition up-regulates PTTG1-binding protein which promotes HCC tumor growth and cell invasion
    • Li, C., Wang, Y., Wang, S., Wu, B., Hao, J., Fan, H., Ju, Y., Ding, Y., Chen, L., Chu, X., Liu, W., Ye, X., and Meng, S. (2012) HBV mRNAs-mediated miR-122 inhibition up-regulates PTTG1-binding protein which promotes HCC tumor growth and cell invasion. J. Virol. 87, 2193-2205
    • (2012) J. Virol. , vol.87 , pp. 2193-2205
    • Li, C.1    Wang, Y.2    Wang, S.3    Wu, B.4    Hao, J.5    Fan, H.6    Ju, Y.7    Ding, Y.8    Chen, L.9    Chu, X.10    Liu, W.11    Ye, X.12    Meng, S.13
  • 28
    • 24644483623 scopus 로고    scopus 로고
    • Molecular biology: Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA
    • DOI 10.1126/science.1113329
    • Jopling, C. L., Yi, M., Lancaster, A. M., Lemon, S. M., and Sarnow, P. (2005) Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science 309, 1577-1581 (Pubitemid 41266486)
    • (2005) Science , vol.309 , Issue.5740 , pp. 1577-1581
    • Jopling, C.L.1    Yi, M.2    Lancaster, A.M.3    Lemon, S.M.4    Sarnow, P.5
  • 29
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • DOI 10.1016/j.cell.2004.12.035, PII S0092867404012607
    • Lewis, B. P., Burge, C. B., and Bartel, D. P. (2005) Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120, 15-20 (Pubitemid 40094598)
    • (2005) Cell , vol.120 , Issue.1 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 31
    • 33750370444 scopus 로고    scopus 로고
    • MicroRNA signatures in human cancers
    • DOI 10.1038/nrc1997, PII NRC1997
    • Calin, G. A., and Croce, C. M. (2006) MicroRNA signatures in human cancers. Nat. Rev. Cancer 6, 857-866 (Pubitemid 44629897)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.11 , pp. 857-866
    • Calin, G.A.1    Croce, C.M.2
  • 32
    • 0035992384 scopus 로고    scopus 로고
    • Clinicopathological significance of loss of heterozygosity on chromosome 13q in hepatocellular carcinoma
    • Wong, C. M., Lee, J. M., Lau, T. C., Fan, S. T., and Ng, I. O. (2002) Clinicopathological significance of loss of heterozygosity on chromosome 13q in hepatocellular carcinoma. Clin Cancer Res. 8, 2266-2272 (Pubitemid 34753600)
    • (2002) Clinical Cancer Research , vol.8 , Issue.7 , pp. 2266-2272
    • Wong, C.M.1    Lee, J.M.F.2    Lau, T.C.M.3    Fan, S.T.4    Ng, I.O.L.5
  • 33
    • 77958152970 scopus 로고    scopus 로고
    • Suppression of hepatitis B virus replication by microRNA-199a-3p and microRNA-210
    • Zhang, G. L., Li, Y. X., Zheng, S. Q., Liu, M., Li, X., and Tang, H. (2010) Suppression of hepatitis B virus replication by microRNA-199a-3p and microRNA-210. Antiviral Res. 88, 169-175
    • (2010) Antiviral Res. , vol.88 , pp. 169-175
    • Zhang, G.L.1    Li, Y.X.2    Zheng, S.Q.3    Liu, M.4    Li, X.5    Tang, H.6
  • 35
    • 0031952176 scopus 로고    scopus 로고
    • Cloning and characterization of a novel hepatitis B virus x binding protein that inhibits viral replication
    • Melegari, M., Scaglioni, P. P., and Wands, J. R. (1998) Cloning and characterization of a novel hepatitis B virusXbinding protein that inhibits viral replication. J. Virol. 72, 1737-1743 (Pubitemid 28100722)
    • (1998) Journal of Virology , vol.72 , Issue.3 , pp. 1737-1743
    • Melegari, M.1    Scaglioni, P.P.2    Wands, J.R.3
  • 36
    • 77957850291 scopus 로고    scopus 로고
    • Emerging roles for natural microRNA sponges
    • Ebert, M. S., and Sharp, P. A. (2010) Emerging roles for natural microRNA sponges. Curr. Biol. 20, R858-R861
    • (2010) Curr. Biol. , vol.20
    • Ebert, M.S.1    Sharp, P.A.2
  • 37
    • 79955109306 scopus 로고    scopus 로고
    • Modulation of hepatitis B virus replication and hepatocyte differentiation by MicroRNA-1
    • Zhang, X., Zhang, E., Ma, Z., Pei, R., Jiang, M., Schlaak, J. F., Roggendorf, M., and Lu, M. (2011) Modulation of hepatitis B virus replication and hepatocyte differentiation by MicroRNA-1. Hepatology 53, 1476-1485
    • (2011) Hepatology , vol.53 , pp. 1476-1485
    • Zhang, X.1    Zhang, E.2    Ma, Z.3    Pei, R.4    Jiang, M.5    Schlaak, J.F.6    Roggendorf, M.7    Lu, M.8
  • 38
    • 84863116887 scopus 로고    scopus 로고
    • Loss of microRNA 122 expression in patients with hepatitis B enhances hepatitis B virus replication through cyclin G(1)-modulated P53 activity
    • Wang, S., Qiu, L., Yan, X., Jin, W., Wang, Y., Chen, L., Wu, E., Ye, X., Gao, G. F., Wang, F., Chen, Y., Duan, Z., and Meng, S. (2012) Loss of microRNA 122 expression in patients with hepatitis B enhances hepatitis B virus replication through cyclin G(1)-modulated P53 activity. Hepatology 55, 730-741
    • (2012) Hepatology , vol.55 , pp. 730-741
    • Wang, S.1    Qiu, L.2    Yan, X.3    Jin, W.4    Wang, Y.5    Chen, L.6    Wu, E.7    Ye, X.8    Gao, G.F.9    Wang, F.10    Chen, Y.11    Duan, Z.12    Meng, S.13


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