Inhibition of Factor XI activity as a promising antithrombotic strategy

Drug Discovery Today

Volumn 19, Issue 9, 2014, Pages 1435-1439

  Chen, Zhu ^a   Seiffert, Dietmar ^a   Hawes, Brian ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; BLOOD CLOTTING FACTOR 11; NEUTRALIZING ANTIBODY; FIBRINOLYTIC AGENT;

ANTICOAGULATION; BLEEDING TIME; BRAIN ISCHEMIA; DEEP VEIN THROMBOSIS; DRUG INHIBITION; FIBRIN FORMATION; HEART INFARCTION; HUMAN; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; REVIEW; RISK ASSESSMENT; THROMBOELASTOGRAPHY; THROMBOSIS; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; DISEASE MODEL; DRUG DESIGN; DRUG DEVELOPMENT; HEMORRHAGE; PROCEDURES; THROMBOEMBOLISM;

ANIMALS; DISEASE MODELS, ANIMAL; DRUG DESIGN; DRUG DISCOVERY; FACTOR XI; FIBRINOLYTIC AGENTS; HEMORRHAGE; HUMANS; THROMBOEMBOLISM;

EID: 84907859951     PISSN: 13596446     EISSN: 18785832     Source Type: Journal    
DOI: 10.1016/j.drudis.2014.04.018     Document Type: Review

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