메뉴 건너뛰기




Volumn 87, Issue SUPPL. 1, 2012, Pages

New oral anticoagulants: A view from the laboratory

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED PROTEIN C; APIXABAN; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 11; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 9; DABIGATRAN ETEXILATE; FONDAPARINUX; PLACEBO; RIVAROXABAN; THROMBIN; THROMBOPLASTIN; WARFARIN; XIMELAGATRAN;

EID: 84859971651     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.23139     Document Type: Article
Times cited : (29)

References (20)
  • 2
    • 70349306707 scopus 로고    scopus 로고
    • Dabigatran versus warfarin in patients with atrial fibrillation
    • Connolly SJ, Ezekowitz MD, Yusuf S, et al. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 2009; 361: 1139-1151.
    • (2009) N Engl J Med , vol.361 , pp. 1139-1151
    • Connolly, S.J.1    Ezekowitz, M.D.2    Yusuf, S.3
  • 3
    • 80052592404 scopus 로고    scopus 로고
    • Rivaroxaban versus warfarin in nonvalvular atrial fibrillation
    • Patel MR, Mahaffey KW, Garg J, et al. Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N Engl J Med 2011; 365: 883-891.
    • (2011) N Engl J Med , vol.365 , pp. 883-891
    • Patel, M.R.1    Mahaffey, K.W.2    Garg, J.3
  • 4
    • 80052825103 scopus 로고    scopus 로고
    • Apixaban versus warfarin in patients with atrial fibrillation
    • Granger CB, Alexander JH, McMurray JJ, et al. Apixaban versus warfarin in patients with atrial fibrillation. N Engl J Med 2011; 365: 981-982.
    • (2011) N Engl J Med , vol.365 , pp. 981-982
    • Granger, C.B.1    Alexander, J.H.2    McMurray, J.J.3
  • 5
    • 0035871772 scopus 로고    scopus 로고
    • Prothrombin protects factor Xa in the prothrombinase complex from inhibition by the heparin-antithrombin complex
    • Rezaie, AR. Prothrombin protects factor Xa in the prothrombinase complex from inhibition by the heparin-antithrombin complex. Blood 2001; 97: 2308-2313.
    • (2001) Blood , vol.97 , pp. 2308-2313
    • Rezaie, A.R.1
  • 6
    • 2142812859 scopus 로고    scopus 로고
    • Factor Xa is highly protected from antithrombin-fondaparinux and antithrombin-enoxaparin when incorporated into the prothrombinase complex
    • Brufatto N, Ward A, Nesheim ME. Factor Xa is highly protected from antithrombin-fondaparinux and antithrombin-enoxaparin when incorporated into the prothrombinase complex. J Thromb Haemost 2003; 1: 1258-1263.
    • (2003) J Thromb Haemost , vol.1 , pp. 1258-1263
    • Brufatto, N.1    Ward, A.2    Nesheim, M.E.3
  • 7
    • 34250755638 scopus 로고    scopus 로고
    • Factor Xa or thrombin: is thrombin a better target?
    • Weitz JI. Factor Xa or thrombin: is thrombin a better target? J Thromb Haemost 2007; 5(Suppl 1): 65-67.
    • (2007) J Thromb Haemost , vol.5 , Issue.SUPPL. 1 , pp. 65-67
    • Weitz, J.I.1
  • 8
    • 0025146426 scopus 로고
    • Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors
    • Weitz JI, Hudoba M, Massel D, et al. Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors. J Clin Invest 1990; 86: 385-391.
    • (1990) J Clin Invest , vol.86 , pp. 385-391
    • Weitz, J.I.1    Hudoba, M.2    Massel, D.3
  • 9
    • 34250700118 scopus 로고    scopus 로고
    • Factor Xa or thrombin: is factor Xa a better target?
    • Ansell J. Factor Xa or thrombin: is factor Xa a better target? J Thromb Haemost 2007; 5(Suppl 1): 60-64.
    • (2007) J Thromb Haemost , vol.5 , Issue.SUPPL. 1 , pp. 60-64
    • Ansell, J.1
  • 10
    • 71849117615 scopus 로고    scopus 로고
    • Dabigatran versus warfarin in the treatment of acute venous thromboembolism
    • Schulman S, Kearon C, Kakkar AK, et al. Dabigatran versus warfarin in the treatment of acute venous thromboembolism. N Engl J Med 2009; 361: 2342-2352.
    • (2009) N Engl J Med , vol.361 , pp. 2342-2352
    • Schulman, S.1    Kearon, C.2    Kakkar, A.K.3
  • 11
    • 78650619315 scopus 로고    scopus 로고
    • Oral rivaroxaban for symptomatic venous thromboembolism
    • EINSTEIN Investigators
    • EINSTEIN Investigators, Bauersachs R, Berkowitz SD, et al. Oral rivaroxaban for symptomatic venous thromboembolism. N Engl J Med 2010; 363: 2499-2510.
    • (2010) N Engl J Med , vol.363 , pp. 2499-2510
    • Bauersachs, R.1    Berkowitz, S.D.2
  • 12
    • 77949312944 scopus 로고    scopus 로고
    • Drug-induced liver injury in humans: the case of ximelagatran
    • Keisu M, Andersson TB. Drug-induced liver injury in humans: the case of ximelagatran. Handb Exp Pharmacol 2010; 196: 407-418.
    • (2010) Handb Exp Pharmacol , vol.196 , pp. 407-418
    • Keisu, M.1    Andersson, T.B.2
  • 13
    • 81355124069 scopus 로고    scopus 로고
    • Anticoagulants and the propagation phase of thrombin generation
    • Epub ahead of print).
    • Orfeo T, Gissel M, Butenas S, et al. Anticoagulants and the propagation phase of thrombin generation. PLoS One 2011; 6: e27852 (Epub ahead of print).
    • (2011) PLoS One , vol.6
    • Orfeo, T.1    Gissel, M.2    Butenas, S.3
  • 14
    • 34447522035 scopus 로고    scopus 로고
    • In-vitro profile and ex-vivo anticoagulant activity of the direct thrombin inhibitor dabigatran and its orally active prodrug, dabigatran etexilate
    • Wienen W, Stassen JM, Priepke H, et al. In-vitro profile and ex-vivo anticoagulant activity of the direct thrombin inhibitor dabigatran and its orally active prodrug, dabigatran etexilate. Thromb Haemost 2007; 98: 155-162.
    • (2007) Thromb Haemost , vol.98 , pp. 155-162
    • Wienen, W.1    Stassen, J.M.2    Priepke, H.3
  • 15
    • 34147147085 scopus 로고    scopus 로고
    • In vitro inhibition of thrombin generation, after tissue factor pathway activation, by the oral, direct factor Xa inhibitor rivaroxaban
    • Gerotziafas GT, Elalamy I, Depasse F, et al. In vitro inhibition of thrombin generation, after tissue factor pathway activation, by the oral, direct factor Xa inhibitor rivaroxaban. J Thromb Haemost 2007; 5: 886-888.
    • (2007) J Thromb Haemost , vol.5 , pp. 886-888
    • Gerotziafas, G.T.1    Elalamy, I.2    Depasse, F.3
  • 17
    • 38749131205 scopus 로고    scopus 로고
    • The metabolism and disposition of the oral direct thrombin inhibitor, dabigatran, in humans
    • Blech S, Ebner T, Ludwig-Schwellinger E, et al. The metabolism and disposition of the oral direct thrombin inhibitor, dabigatran, in humans. Drug Metab Dispos 2008; 36: 386-399.
    • (2008) Drug Metab Dispos , vol.36 , pp. 386-399
    • Blech, S.1    Ebner, T.2    Ludwig-Schwellinger, E.3
  • 18
    • 79958126202 scopus 로고    scopus 로고
    • Risk of bleeding with 2 doses of dabigatran compared with warfarin in older and younger patients with atrial fibrillation: an analysis of the randomized evaluation of long-term anticoagulant therapy (RE-LY) trial
    • Eikelboom JW, Wallentin L, Connolly SJ, et al. Risk of bleeding with 2 doses of dabigatran compared with warfarin in older and younger patients with atrial fibrillation: an analysis of the randomized evaluation of long-term anticoagulant therapy (RE-LY) trial. Circulation 2011; 123: 2363-2372.
    • (2011) Circulation , vol.123 , pp. 2363-2372
    • Eikelboom, J.W.1    Wallentin, L.2    Connolly, S.J.3
  • 19
    • 84863142762 scopus 로고    scopus 로고
    • Myocardial ischemic events in patients with atrial fibrillation treated with dabigatran or warfarin in the RE-LY Trial
    • Hohnloser SH, Oldgren J, Yang S, et al. Myocardial ischemic events in patients with atrial fibrillation treated with dabigatran or warfarin in the RE-LY Trial. Circulation 2012; 125: 669-676.
    • (2012) Circulation , vol.125 , pp. 669-676
    • Hohnloser, S.H.1    Oldgren, J.2    Yang, S.3
  • 20
    • 84859961880 scopus 로고    scopus 로고
    • Dabigatran associated with higher risk of acute coronary events: meta-analysis of noninferiority randomized controlled trials
    • Epub ahead of print].
    • Uchino K, Hernandez AV. Dabigatran associated with higher risk of acute coronary events: meta-analysis of noninferiority randomized controlled trials. Arch Intern Med 2011; 2012 [Epub ahead of print].
    • (2011) Arch Intern Med , pp. 2012
    • Uchino, K.1    Hernandez, A.V.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.