A non-redundant role for MKP5 in limiting ROS production and preventing LPS-induced vascular injury

EMBO Journal

Volumn 28, Issue 19, 2009, Pages 2896-2907

  Qian, Feng ^a   Deng, Jing ^a   Cheng, Ni ^a   Welch, Emily J ^a   Zhang, Yongliang ^b   Malik, Asrar B ^a   Flavell, Richard A ^c   Dong, Chen ^b   Ye, Richard D ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

LPS; MAPK; MKP5; NADPH oxidase; Neutrophils

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; MYELOPEROXIDASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL INJURY; CELL DIVISION; CELL ISOLATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; GENE DELETION; GENE LOSS; IN VIVO STUDY; INFLAMMATION; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SHWARTZMAN PHENOMENON; SKIN DEFECT; WILD TYPE;

ANIMALS; DUAL-SPECIFICITY PHOSPHATASES; GENE DELETION; LIPOPOLYSACCHARIDES; MICE; MICROVESSELS; NADPH OXIDASE; NEUTROPHILS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; REACTIVE OXYGEN SPECIES; SUPEROXIDES;

MUS;

EID: 70350573933     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2009.234     Document Type: Article

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