Curcuma oil modulates the nitric oxide system response to cerebral ischemia/reperfusion injury

Nitric Oxide - Biology and Chemistry

Volumn 19, Issue 1, 2008, Pages 1-11

  Dohare, Preeti ^a   Varma, Saurabh ^b   Ray, Madhur ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b SAFDARJUNG HOSPITAL CAMPUS   (India)

Author keywords

Apoptosis; MCAo; Rat; Transient focal ischemia; TUNEL

Indexed keywords

CURCUMA EXTRACT; NITRIC OXIDE; PEROXYNITRITE; REACTIVE OXYGEN METABOLITE; VEGETABLE OIL;

ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; CURCUMA LONGA; DNA FRAGMENTATION; DRUG ACTIVITY; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; RAT; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BRAIN ISCHEMIA; CEREBRAL INFARCTION; CURCUMA; CYTOCHROME C GROUP; DNA FRAGMENTATION; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; IN SITU NICK-END LABELING; MALE; MITOCHONDRIA; NEURONS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OILS, VOLATILE; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

CURCUMA; CURCUMA LONGA; RATTUS;

EID: 46149118615     PISSN: 10898603     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.niox.2008.04.020     Document Type: Article

References (37)

1. Jain V., Prasad V., Pal R., and Singh S. Standardization and stability studies of neuroprotective lipid soluble fraction obtained from Curcuma longa. J. Pharm. Biomed. Anal. 44 (2007) 1079-1086
2. M. Ray, R. Pal, S. Singh, N.M. Khanna, Herbal medicaments for the treatment of neurocerebrovascular disorders, US Patent No.: 6991814 Grant Date: 31/01/2006 Patent Appl. No.: 10/319373, 2006.
3. STAIR. Recommendations for standards regarding preclinical neuroprotective and restorative drug development. Stroke 30 (1999) 2752-2758
4. Lestage P., Lockhart B., and Roger A. In vivo exploration of cerebral ischemia: use of neuroprotective agents in animal studies. Therapie 57 (2002) 554-563
5. P. Rathore, P. Dohare, S. Varma, A. Ray, U. Sharma, N.R. Jaganathanan, M. Ray, Curcuma oil: reduces early accumulation of oxidative product and is anti-apoptogenic in transient focal ischemia in rat brain, Neurochem. Res. (online available).
6. Fisher M., Jonas S., Sacco R.L., and Jones S. Prophylactic neuroprotection for cerebral ischemia. Stroke 25 (1994) 1075-1080
7. Jadhav V., Solaroglu I., Obenaus A., and Zhang J.H. Neuroprotection against surgically induced brain injury. Surg. Neurol. 67 (2007) 15-20 (discussion 20)
8. Green A.R., and Shuaib A. Therapeutic strategies for the treatment of stroke. Drug Discov. Today 11 (2006) 681-693
9. Longa E.Z., Weinstein P.R., Carlson S., and Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20 (1989) 84-91
10. Gershenzon J., and Dudareva N. The function of terpene natural products in the natural world. Nat. Chem. Biol. 3 (2007) 408-414
11. Wang C.X., Yang Y., Yang T., and Shuaib A. A focal embolic model of cerebral ischemia in rats: introduction and evaluation. Brain Res. Protoc. 7 (2001) 115-120
12. Rastogi L., Godbole M.M., Ray M., Rathore P., Rathore P., Pradhan S., Gupta S.K., and Pandey C.M. Reduction in oxidative stress and cell death explains hypothyroidism induced neuroprotection subsequent to ischemia/reperfusion insult. Exp. Neurol. 200 (2006) 290-300
13. Swanson R.A., Morton M.T., Tsao-Wu G., Savalos R.A., Davidson C., and Sharp F.R. A semiautomated method for measuring brain infarct volume. J. Cereb. Blood Flow Metab. 10 (1990) 290-293
14. Martinez-Lara E., Canuelo A.R., Siles E., Hernandez R., Del Moral M.L., Blanco S., Pedrosa J.A., Rodrigo J., and Peinado M.A. Constitutive nitric oxide synthases are responsible for the nitric oxide production in the ischemic aged cerebral cortex. Brain Res. 1054 (2005) 88-94
15. Barone F.C., Hillegass L.M., Price W.J., White R.F., Lee E.V., Feuerstein G.Z., Sarau H.M., Clark R.K., and Griswold D.E. Polymorphonuclear leukocyte infiltration into cerebral focal ischemic tissue: myeloperoxidase activity assay and histologic verification. J. Neurosci. Res. 29 (1991) 336-345
16. Crow J.P. Dichlorodihydrofluorescein and dihydrorhodamine 123 are sensitive indicators of peroxynitrite in vitro: implications for intracellular measurement of reactive nitrogen and oxygen species. Nitric Oxide 1 (1997) 145-157
17. Kooy N.W., Royall J.A., Ischiropoulos H., and Beckman J.S. Peroxynitrite-mediated oxidation of dihydrorhodamine 123. Free Radic. Biol. Med. 16 (1994) 149-156
18. Emaus R.K., Grunwald R., and Lemasters J.J. Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties. Biochim. Biophys. Acta 850 (1986) 436-448
19. 2+ of brain neurons: a technical aspect. Brain Res. 728 (1996) 121-124
20. Guo W.P., Wang J., Li R.X., and Peng Y.W. Neuroprotective effects of neuregulin-1 in rat models of focal cerebral ischemia. Brain Res. 1087 (2006) 180-185
21. Ren M., Leng Y., Jeong M., Leeds P.R., and Chuang D.M. Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: potential roles of histone deacetylase inhibition and heat shock protein induction. J. Neurochem. 89 (2004) 1358-1367
22. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193 (1951) 265-275
23. Reempts J.V., and Borgers M. Animal models of stroke: compromise between consistency and clinical relevance?. Neurosci. Res. Commun. 26 (2000) 161-172
24. Tan K.H., Harrington S., Purcell W.M., and Hurst R.D. Peroxynitrite mediates nitric oxide-induced blood-brain barrier damage. Neurochem. Res. 29 (2004) 579-587
25. Beckman J.S., Beckman T.W., Chen J., Marshall P.A., and Freeman B.A. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc. Natl. Acad. Sci. USA 87 (1990) 1620-1624
26. Estevez A.G., Radi R., Barbeito L., Shin J.T., Thompson J.A., and Beckman J.S. Peroxynitrite-induced cytotoxicity in PC12 cells: evidence for an apoptotic mechanism differentially modulated by neurotrophic factors. J. Neurochem. 65 (1995) 1543-1550
27. Almeida A., and Bolanos J.P. A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons. J. Neurochem. 77 (2001) 676-690
28. Dawson V.L., Dawson T.M., London E.D., Bredt D.S., and Snyder S.H. Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures. Proc. Natl. Acad. Sci. USA 88 (1991) 6368-6371
29. Holtz M.L., Craddock S.D., and Pettigrew L.C. Rapid expression of neuronal and inducible nitric oxide synthases during post-ischemic reperfusion in rat brain. Brain Res. 898 (2001) 49-60
30. Leker R.R., Teichner A., Ovadia H., Keshet E., Reinherz E., and Ben-Hur T. Expression of endothelial nitric oxide synthase in the ischemic penumbra: relationship to expression of neuronal nitric oxide synthase and vascular endothelial growth factor. Brain Res. 909 (2001) 1-7
31. Nathan C., and Xie Q.W. Regulation of biosynthesis of nitric oxide. J. Biol. Chem. 269 (1994) 13725-13728
32. Zhu D.Y., Deng Q., Yao H.H., Wang D.C., Deng Y., and Liu G.Q. Inducible nitric oxide synthase expression in the ischemic core and penumbra after transient focal cerebral ischemia in mice. Life Sci. 71 (2002) 1985-1996
33. Togashi H., Sasaki M., Frohman E., Taira E., Ratan R.R., Dawson T.M., and Dawson V.L. Neuronal (type I) nitric oxide synthase regulates nuclear factor kappaB activity and immunologic (type II) nitric oxide synthase expression. Proc. Natl. Acad. Sci. USA 94 (1997) 2676-2680
34. Lantz R.C., Chen G.J., Solyom A.M., Jolad S.D., and Timmermann B.N. The effect of turmeric extracts on inflammatory mediator production. Phytomedicine 12 (2005) 445-452
35. Niwa M., Hara A., Iwai T., Wang S., Hotta K., Mori H., and Uematsu T. Caspase activation as an apoptotic evidence in the gerbil hippocampal CA1 pyramidal cells following transient forebrain ischemia. Neurosci. Lett. 300 (2001) 103-106
36. Watanabe H., Ohta S., Kumon Y., Sakaki S., and Sakanaka M. Increase in p53 protein expression following cortical infarction in the spontaneously hypertensive rat. Brain Res. 837 (1999) 38-45
37. Xiang H., Hochman D.W., Saya H., Fujiwara T., Schwartzkroin P.A., and Morrison R.S. Evidence for p53-mediated modulation of neuronal viability. J. Neurosci. 16 (1996) 6753-6765