메뉴 건너뛰기




Volumn 8, Issue 5, 2014, Pages 1416-1422

Clinical significance of mismatch repair gene expression in sporadic colorectal cancer

Author keywords

Clinicopathological parameters; Immunohistochemistry; Mismatch repair genes; Prognosis; Sporadic colorectal cancer

Indexed keywords

MISMATCH REPAIR PROTEIN PMS2; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6;

EID: 84907812990     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2014.1927     Document Type: Article
Times cited : (15)

References (49)
  • 1
    • 84878032599 scopus 로고    scopus 로고
    • Geographic epidemiology in a small area: Cancer incidence in Baakline, Lebanon, 2000-2008
    • Adib SM, Tabbal N, Hamadeh R and Ammar W: Geographic epidemiology in a small area: cancer incidence in Baakline, Lebanon, 2000-2008. East Mediterr Health J 19: 320-326, 2013.
    • (2013) East Mediterr Health J , vol.19 , pp. 320-326
    • Adib, S.M.1    Tabbal, N.2    Hamadeh, R.3    Ammar, W.4
  • 2
    • 79954435158 scopus 로고    scopus 로고
    • Colorectal cancer epigenetics: Complex simplicity
    • Van Engeland M, Derks S, Smits KM, et al: Colorectal cancer epigenetics: complex simplicity. J Clin Oncol 29: 1382-1391, 2011.
    • (2011) J Clin Oncol , vol.29 , pp. 1382-1391
    • Van Engeland, M.1    Derks, S.2    Smits, K.M.3
  • 3
    • 78650215962 scopus 로고    scopus 로고
    • Lynch syndrome: The influence of environmental factors on extracolonic cancer risk in hMLH1 c.C1528T mutation carriers and their mutation-negative sisters
    • Blokhuis MM, Pietersen GE, Goldberg PA, et al: Lynch syndrome: the influence of environmental factors on extracolonic cancer risk in hMLH1 c.C1528T mutation carriers and their mutation-negative sisters. Fam Cancer 9: 357-363, 2010.
    • (2010) Fam Cancer , vol.9 , pp. 357-363
    • Blokhuis, M.M.1    Pietersen, G.E.2    Goldberg, P.A.3
  • 4
    • 0027742295 scopus 로고
    • The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
    • Fishel R, Lescoe MK, Rao MR, et al: The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 75: 1027-1038, 1993.
    • (1993) Cell , vol.75 , pp. 1027-1038
    • Fishel, R.1    Lescoe, M.K.2    Rao, M.R.3
  • 5
    • 0032555020 scopus 로고    scopus 로고
    • Incidence of hereditary nonpolyposis colorectal cancer and the feasibility of molecular screening for the disease
    • Aaltonen LA, Salovaara R, Kristo P, et al: Incidence of hereditary nonpolyposis colorectal cancer and the feasibility of molecular screening for the disease. N Engl J Med 338: 1481-1487, 1998.
    • (1998) N Engl J Med , vol.338 , pp. 1481-1487
    • Aaltonen, L.A.1    Salovaara, R.2    Kristo, P.3
  • 6
    • 84874026816 scopus 로고    scopus 로고
    • Immunohistochemical screening of hMLH1 and hMSH2 gene mutations in patients diagnosed with colorectal cancer and microsatellite instability suspicion
    • (In Romanian)
    • Mureşan F, Simescu R, Domşa I, et al: Immunohistochemical screening of hMLH1 and hMSH2 gene mutations in patients diagnosed with colorectal cancer and microsatellite instability suspicion. Chirurgia (Bucur) 106: 775-780, 2011 (In Romanian).
    • (2011) Chirurgia (Bucur) , vol.106 , pp. 775-780
    • Mureşan, F.1    Simescu, R.2    Domşa, I.3
  • 7
    • 79958733350 scopus 로고    scopus 로고
    • Distinct mutations in MLH1 and MSH2 genes in hereditary non-polyposis colorectal cancer (HNPCC) families from China
    • Wei W, Liu F, Liu L, et al: Distinct mutations in MLH1 and MSH2 genes in hereditary non-polyposis colorectal cancer (HNPCC) families from China. BMB Rep 44: 317-322, 2011.
    • (2011) BMB Rep , vol.44 , pp. 317-322
    • Wei, W.1    Liu, F.2    Liu, L.3
  • 8
    • 0031551963 scopus 로고    scopus 로고
    • A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: Meeting highlights and Bethesda guidelines
    • Rodriguez-Bigas MA, Boland CR, Hamilton SR, et al: A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: meeting highlights and Bethesda guidelines. J Natl Cancer Inst 89: 1758-1762.
    • J Natl Cancer Inst , vol.89 , pp. 1758-1762
    • Rodriguez-Bigas, M.A.1    Boland, C.R.2    Hamilton, S.R.3
  • 9
    • 0029833872 scopus 로고    scopus 로고
    • Hereditary nonpolyposis colorectal cancer (Lynch syndrome). An updated review
    • Lynch HT and Smyrk T: Hereditary nonpolyposis colorectal cancer (Lynch syndrome). An updated review. Cancer 78: 1149-1167, 1996.
    • (1996) Cancer , vol.78 , pp. 1149-1167
    • Lynch, H.T.1    Smyrk, T.2
  • 10
    • 84860605783 scopus 로고    scopus 로고
    • Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation: A prospective cohort study
    • Aung Ko Win, Joanne P Young, et al: Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation: a prospective cohort study. J Clin Oncol 30: 958-964, 2012.
    • (2012) J Clin Oncol , vol.30 , pp. 958-964
    • Win, A.K.1    Young, J.P.2
  • 11
    • 22044456306 scopus 로고    scopus 로고
    • The DNA mismatch repair gene hMSH2 is a potent coactivator of oestrogen receptor alpha
    • Wada-Hiraike O, Yano T, Nei T, et al: The DNA mismatch repair gene hMSH2 is a potent coactivator of oestrogen receptor alpha. Br J Cancer 92: 2286-2291, 2005.
    • (2005) Br J Cancer , vol.92 , pp. 2286-2291
    • Wada-Hiraike, O.1    Yano, T.2    Nei, T.3
  • 12
    • 16344363017 scopus 로고    scopus 로고
    • Correlation between hhMLH1/hhMSH2 and p53 protein expression in sporadic colorectal cancer
    • Park IJ, Kim HC, Kim JS, et al: Correlation between hhMLH1/hhMSH2 and p53 protein expression in sporadic colorectal cancer. Hepatogastroenterology 52: 450-454, 2005.
    • (2005) Hepatogastroenterology , vol.52 , pp. 450-454
    • Park, I.J.1    Kim, H.C.2    Kim, J.S.3
  • 13
    • 84859881009 scopus 로고    scopus 로고
    • Analysis and interpretation of RNA splicing alterations in genes involved in genetic disorders
    • Vreeswijk MP and van der Klift HM: Analysis and interpretation of RNA splicing alterations in genes involved in genetic disorders. Methods Mol Biol 867: 49-63, 2012.
    • (2012) Methods Mol Biol , vol.867 , pp. 49-63
    • Vreeswijk, M.P.1    van der Klift, H.M.2
  • 14
    • 84907807777 scopus 로고    scopus 로고
    • Relationship between Aberrant Expression of hMSH2 and prognosis in patients with sporadic colorectal cancer
    • Sun ZQ, Yu XB, Wang HJ, et al: Relationship between Aberrant Expression of hMSH2 and prognosis in patients with sporadic colorectal cancer. Canc Cell Rec 2: e47-e54, 2014.
    • (2014) Canc Cell Rec , vol.2 , pp. e47-e54
    • Sun, Z.Q.1    Yu, X.B.2    Wang, H.J.3
  • 15
    • 84904543667 scopus 로고    scopus 로고
    • Gut microbial metabolism drives transformation of msh2-deficient colon epithelial cells
    • Belcheva A, Irrazabal T, Robertson SJ, et al: Gut microbial metabolism drives transformation of msh2-deficient colon epithelial cells. Cell 158: 288-299, 2014.
    • (2014) Cell , vol.158 , pp. 288-299
    • Belcheva, A.1    Irrazabal, T.2    Robertson, S.J.3
  • 16
    • 0034827025 scopus 로고    scopus 로고
    • The frequency of hereditary defective mismatch repair in a prospective series of unselected colorectal carcinomas
    • Cunningham JM, Kim CY, Chirstensen ER, et al: The frequency of hereditary defective mismatch repair in a prospective series of unselected colorectal carcinomas. Am J Hum Genet 69: 780-790, 2001.
    • (2001) Am J Hum Genet , vol.69 , pp. 780-790
    • Cunningham, J.M.1    Kim, C.Y.2    Chirstensen, E.R.3
  • 17
    • 0027285475 scopus 로고
    • Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
    • Ionov Y, Peinado MA, Malkhosyan S, et al: Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 363: 558-561, 1993.
    • (1993) Nature , vol.363 , pp. 558-561
    • Ionov, Y.1    Peinado, M.A.2    Malkhosyan, S.3
  • 18
    • 14544300998 scopus 로고    scopus 로고
    • Systematic review of microsatellite instability and colorectal cancer prognosis
    • Popat S, Hubner R and Houlston RS: Systematic review of microsatellite instability and colorectal cancer prognosis. J Clin Oncol 23: 609-618, 2005.
    • (2005) J Clin Oncol , vol.23 , pp. 609-618
    • Popat, S.1    Hubner, R.2    Houlston, R.S.3
  • 19
    • 0038002279 scopus 로고    scopus 로고
    • Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer
    • Ribic CM, Sargent DJ, Moore MJ, et al: Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer. N Engl J Med 349: 247-257, 2003.
    • (2003) N Engl J Med , vol.349 , pp. 247-257
    • Ribic, C.M.1    Sargent, D.J.2    Moore, M.J.3
  • 20
    • 77954748953 scopus 로고    scopus 로고
    • Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer
    • Sargent DJ, Marsoni S, Monges G, et al: Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer. J Clin Oncol 28: 3219-3226, 2010.
    • (2010) J Clin Oncol , vol.28 , pp. 3219-3226
    • Sargent, D.J.1    Marsoni, S.2    Monges, G.3
  • 21
    • 84879605114 scopus 로고    scopus 로고
    • A 44-year-old woman with hereditary nonpolyposis colon carcinoma: Screening examinations for non-colonic tumors
    • (In German)
    • Holzhüter J, Rösch T, Block A, et al: A 44-year-old woman with hereditary nonpolyposis colon carcinoma: screening examinations for non-colonic tumors. Internist (Berl) 54: 353-358, 2013 (In German).
    • (2013) Internist (Berl) , vol.54 , pp. 353-358
    • Holzhüter, J.1    Rösch, T.2    Block, A.3
  • 22
    • 3142682227 scopus 로고    scopus 로고
    • Immunohistochemical detection of the hMLH1 and hMSH2 proteins in hereditary non-polyposis colon cancer and sporadic colon cancer
    • Plevová P, Krepelová A, Papezová M, et al: Immunohistochemical detection of the hMLH1 and hMSH2 proteins in hereditary non-polyposis colon cancer and sporadic colon cancer. Neoplasma 51: 275-284, 2004.
    • (2004) Neoplasma , vol.51 , pp. 275-284
    • Plevová, P.1    Krepelová, A.2    Papezová, M.3
  • 23
    • 0037083484 scopus 로고    scopus 로고
    • Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors
    • Lindor NM, Burgart LJ, Leontovich O, et al: Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors. J Clin Oncol 20: 1043-1048, 2002.
    • (2002) J Clin Oncol , vol.20 , pp. 1043-1048
    • Lindor, N.M.1    Burgart, L.J.2    Leontovich, O.3
  • 24
    • 12244278227 scopus 로고    scopus 로고
    • Correlation of mismatch repair genes immunohistochemistry and microsatellite instability status in HNPCC-associated tumours
    • Ruszkiewicz A, Bennett G, Moore J, et al: Correlation of mismatch repair genes immunohistochemistry and microsatellite instability status in HNPCC-associated tumours. Pathology 34: 541-547, 2002.
    • (2002) Pathology , vol.34 , pp. 541-547
    • Ruszkiewicz, A.1    Bennett, G.2    Moore, J.3
  • 25
    • 11144279281 scopus 로고    scopus 로고
    • Value of immunohistochemical detection of DNA mismatch repair proteins in predicting germline mutation in hereditary colorectal neoplasms
    • Shia J, Klimstra DS, Nafa K, et al: Value of immunohistochemical detection of DNA mismatch repair proteins in predicting germline mutation in hereditary colorectal neoplasms. Am J Surg Pathol 29: 96-104, 2005.
    • (2005) Am J Surg Pathol , vol.29 , pp. 96-104
    • Shia, J.1    Klimstra, D.S.2    Nafa, K.3
  • 26
    • 0032852979 scopus 로고    scopus 로고
    • Immunohistochemistry for hMLH1 and hMSH2: A practical test for DNA mismatch repair-deficient tumors
    • Marcus VA, Madlensky L, Gryfe R, et al: Immunohistochemistry for hMLH1 and hMSH2: a practical test for DNA mismatch repair-deficient tumors. Am J Surg Pathol 23: 1248-1255, 1999.
    • (1999) Am J Surg Pathol , vol.23 , pp. 1248-1255
    • Marcus, V.A.1    Madlensky, L.2    Gryfe, R.3
  • 27
    • 84902939693 scopus 로고    scopus 로고
    • Heterogenous mismatch-repair status in colorectal cancer
    • Joost P, Veurink N, Holck S, et al: Heterogenous mismatch-repair status in colorectal cancer. Diagn Pathol 9: 126, 2014.
    • (2014) Diagn Pathol , vol.9 , pp. 126
    • Joost, P.1    Veurink, N.2    Holck, S.3
  • 28
    • 84897485600 scopus 로고    scopus 로고
    • Telomere shortening: A biological marker of sporadic colorectal cancer with normal expression of p53 and mismatch repair proteins
    • Haghighi MM, Aghagolzadeh P, Zadeh SM, et al: Telomere shortening: a biological marker of sporadic colorectal cancer with normal expression of p53 and mismatch repair proteins. Genet Test Mol Biomarkers 18: 236-244, 2014.
    • (2014) Genet Test Mol Biomarkers , vol.18 , pp. 236-244
    • Haghighi, M.M.1    Aghagolzadeh, P.2    Zadeh, S.M.3
  • 29
    • 0035812238 scopus 로고    scopus 로고
    • Sporadic colorectal cancers with microsatellite instability and their possible origin in hyperplastic polyps and serrated adenomas
    • Hawkins NJ and Ward RL: Sporadic colorectal cancers with microsatellite instability and their possible origin in hyperplastic polyps and serrated adenomas. J Natl Cancer Inst 93: 1307-1313, 2001.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 1307-1313
    • Hawkins, N.J.1    Ward, R.L.2
  • 30
    • 84897652719 scopus 로고    scopus 로고
    • CpG island methylation of the MLH1, MGMT, DAPK, and CASP8 genes in cancerous and adjacent noncancerous stomach tissues
    • Kupčinskaitė-Noreikienė R, Skiecevičienė J, Jonaitis L, et al: CpG island methylation of the MLH1, MGMT, DAPK, and CASP8 genes in cancerous and adjacent noncancerous stomach tissues. Medicina (Kaunas) 49: 361-366, 2013.
    • (2013) Medicina (Kaunas) , vol.49 , pp. 361-366
    • Kupčinskaitė-Noreikienė, R.1    Skiecevičienė, J.2    Jonaitis, L.3
  • 31
    • 84897056300 scopus 로고    scopus 로고
    • Promoter hypermethylation of DNA repair genes MLH1 and MSH2 in adenocarcinomas and squamous cell carcinomas of the lung
    • Gomes A, Reis-Silva M, Alarcão A, et al: Promoter hypermethylation of DNA repair genes MLH1 and MSH2 in adenocarcinomas and squamous cell carcinomas of the lung. Rev Port Pneumol 20: 20-30, 2014.
    • (2014) Rev Port Pneumol , vol.20 , pp. 20-30
    • Gomes, A.1    Reis-Silva, M.2    Alarcão, A.3
  • 32
    • 72349083209 scopus 로고    scopus 로고
    • Colorectal cancer in Iran: Immunohistochemical profiles of four mismatch repair proteins
    • Molaei M, Mansoori BK, Ghiasi S, et al: Colorectal cancer in Iran: immunohistochemical profiles of four mismatch repair proteins. Int J Colorectal Dis 25: 63-69, 2010.
    • (2010) Int J Colorectal Dis , vol.25 , pp. 63-69
    • Molaei, M.1    Mansoori, B.K.2    Ghiasi, S.3
  • 33
    • 73949154143 scopus 로고    scopus 로고
    • Colorectal cancer due to deficiency in DNA mismatch repair function: A review
    • Bellizzi AM and Frankel WL: Colorectal cancer due to deficiency in DNA mismatch repair function: a review. Adv Anat Pathol 16: 405-417, 2009.
    • (2009) Adv Anat Pathol , vol.16 , pp. 405-417
    • Bellizzi, A.M.1    Frankel, W.L.2
  • 34
    • 33947539706 scopus 로고    scopus 로고
    • Clinicopathologic and pedigree differences in amsterdam I-positive hereditary nonpolyposis colorectal cancer families according to tumor microsatellite instability status
    • Valle L, Perea J, Carbonell P, et al: Clinicopathologic and pedigree differences in amsterdam I-positive hereditary nonpolyposis colorectal cancer families according to tumor microsatellite instability status. J Clin Oncol 25: 781-786, 2007.
    • (2007) J Clin Oncol , vol.25 , pp. 781-786
    • Valle, L.1    Perea, J.2    Carbonell, P.3
  • 35
    • 16544364390 scopus 로고    scopus 로고
    • HNPCC and sporadic MSI-H colorectal cancer: A review of the morphological similarities and differences
    • Jass JR: HNPCC and sporadic MSI-H colorectal cancer: a review of the morphological similarities and differences. Fam Cancer 3: 93-100, 2004.
    • (2004) Fam Cancer , vol.3 , pp. 93-100
    • Jass, J.R.1
  • 36
    • 84902837353 scopus 로고    scopus 로고
    • Immunohistochemical examination of MSH2, PMS2, MLH1, MSH6 compared with the analysis of microsatellite instability in colon adenocarcinoma
    • (In Russian)
    • Raskin GA, Ianus GA, Kornilov AV, et al: Immunohistochemical examination of MSH2, PMS2, MLH1, MSH6 compared with the analysis of microsatellite instability in colon adenocarcinoma. Vopr Onkol 60: 47-50, 2014 (In Russian).
    • (2014) Vopr Onkol , vol.60 , pp. 47-50
    • Raskin, G.A.1    Ianus, G.A.2    Kornilov, A.V.3
  • 37
    • 84898917325 scopus 로고    scopus 로고
    • Molecular and prognostic heterogeneity of microsatellite-unstable colorectal cancer
    • Kim JH and Kang GH: Molecular and prognostic heterogeneity of microsatellite-unstable colorectal cancer. World J Gastroenterol 20: 4230-4243, 2014.
    • (2014) World J Gastroenterol , vol.20 , pp. 4230-4243
    • Kim, J.H.1    Kang, G.H.2
  • 38
    • 84907814266 scopus 로고    scopus 로고
    • Multicenter retrospective analysis of metastatic colorectal cancer (CRC) with high-level microsatellite instability (MSI-H)
    • Goldstein J, Tran B, Ensor J, et al: Multicenter retrospective analysis of metastatic colorectal cancer (CRC) with high-level microsatellite instability (MSI-H). Ann Oncol 25: 1032-1038, 2014.
    • (2014) Ann Oncol , vol.25 , pp. 1032-1038
    • Goldstein, J.1    Tran, B.2    Ensor, J.3
  • 39
    • 0345059244 scopus 로고    scopus 로고
    • Family history and colorectal cancer: Predictors of risk
    • Slattery ML, Levin TR, Ma K, et al: Family history and colorectal cancer: predictors of risk. Cancer Causes Control 14: 879-887, 2003.
    • (2003) Cancer Causes Control , vol.14 , pp. 879-887
    • Slattery, M.L.1    Levin, T.R.2    Ma, K.3
  • 40
    • 34548813612 scopus 로고    scopus 로고
    • Excess body weight and colorectal cancer risk in Canada: Associations in subgroups of clinically defined familial risk of cancer
    • Campbell PT, Cotterchio M, Dicks E, et al: Excess body weight and colorectal cancer risk in Canada: associations in subgroups of clinically defined familial risk of cancer. Cancer Epidemiol Biomarkers Prev 16: 1735-1744, 2007.
    • (2007) Cancer Epidemiol Biomarkers Prev , vol.16 , pp. 1735-1744
    • Campbell, P.T.1    Cotterchio, M.2    Dicks, E.3
  • 41
    • 84880916690 scopus 로고    scopus 로고
    • Do lifestyle factors influence colorectal cancer risk in Lynch syndrome?
    • van Duijnhoven FJ, Botma A, Winkels R, et al: Do lifestyle factors influence colorectal cancer risk in Lynch syndrome? Fam Cancer 12: 285-293, 2013.
    • (2013) Fam Cancer , vol.12 , pp. 285-293
    • van Duijnhoven, F.J.1    Botma, A.2    Winkels, R.3
  • 42
    • 78049431561 scopus 로고    scopus 로고
    • Body mass index increases risk of colorectal adenomas in men with Lynch syndrome: The GEOLynch cohort study
    • Botma A, Nagengast FM, Braem MG, et al: Body mass index increases risk of colorectal adenomas in men with Lynch syndrome: the GEOLynch cohort study. J Clin Oncol 28: 4346-4353, 2010.
    • (2010) J Clin Oncol , vol.28 , pp. 4346-4353
    • Botma, A.1    Nagengast, F.M.2    Braem, M.G.3
  • 43
    • 79959752616 scopus 로고    scopus 로고
    • Body mass index in early adulthood and colorectal cancer risk for carriers and non-carriers of germline mutations in DNA mismatch repair genes
    • Win AK, Dowty JG, English DR, et al: Body mass index in early adulthood and colorectal cancer risk for carriers and non-carriers of germline mutations in DNA mismatch repair genes. Br J Cancer 105: 162-169, 2011.
    • (2011) Br J Cancer , vol.105 , pp. 162-169
    • Win, A.K.1    Dowty, J.G.2    English, D.R.3
  • 44
    • 35348918876 scopus 로고    scopus 로고
    • Molecular analysis of colorectal cancer tumors from patients with mismatch repair proficient hereditary nonpolyposis colorectal cancer suggests novel carcinogenic pathways
    • Sánchez-de-Abajo A, de la Hoya M, van Puijenbroek M, et al: Molecular analysis of colorectal cancer tumors from patients with mismatch repair proficient hereditary nonpolyposis colorectal cancer suggests novel carcinogenic pathways. Clin Cancer Res 13: 5729-5735, 2007.
    • (2007) Clin Cancer Res , vol.13 , pp. 5729-5735
    • Sánchez-De-Abajo, A.1    de la Hoya, M.2    van Puijenbroek, M.3
  • 45
    • 33947304434 scopus 로고    scopus 로고
    • Colorectal carcinogenesis. 1. Hereditary predisposition and colorectal cancer
    • (In French)
    • Karoui M, Tresallet C, Brouquet A, et al: Colorectal carcinogenesis. 1. Hereditary predisposition and colorectal cancer. J Chir (Paris) 144: 13-18, 2007 (In French).
    • (2007) J Chir (Paris) , vol.144 , pp. 13-18
    • Karoui, M.1    Tresallet, C.2    Brouquet, A.3
  • 46
    • 0029991682 scopus 로고    scopus 로고
    • Microsatellite instability and the role of hhMSH2 in sporadic colorectal cancer
    • Bubb VJ, Curtis LJ, Cunningham C, et al: Microsatellite instability and the role of hhMSH2 in sporadic colorectal cancer. Oncogene 12: 2641-2649, 1996.
    • (1996) Oncogene , vol.12 , pp. 2641-2649
    • Bubb, V.J.1    Curtis, L.J.2    Cunningham, C.3
  • 47
    • 0034642605 scopus 로고    scopus 로고
    • Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer
    • Gryfe R, Kim H, Hsieh ET, et al: Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer. N Engl J Med 342: 69-77, 2000.
    • (2000) N Engl J Med , vol.342 , pp. 69-77
    • Gryfe, R.1    Kim, H.2    Hsieh, E.T.3
  • 48
    • 0030061148 scopus 로고    scopus 로고
    • Better survival rates in patients with hMLH1-associated hereditary colorectal cancer
    • Sankila R, Aaltonen LA, Järvinen HJ and Mecklin JP: Better survival rates in patients with hMLH1-associated hereditary colorectal cancer. Gastroenterology 110: 682-687, 1996.
    • (1996) Gastroenterology , vol.110 , pp. 682-687
    • Sankila, R.1    Aaltonen, L.A.2    Järvinen, H.J.3    Mecklin, J.P.4
  • 49
    • 0033564464 scopus 로고    scopus 로고
    • Influence of selection criteria on mutation detection in patients with hereditary nonpolyposis colorectal cancer
    • Heinimann K, Scott RJ, Buerstedde JM, et al: Influence of selection criteria on mutation detection in patients with hereditary nonpolyposis colorectal cancer. Cancer 85: 2512-2518, 1999.
    • (1999) Cancer , vol.85 , pp. 2512-2518
    • Heinimann, K.1    Scott, R.J.2    Buerstedde, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.