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Volumn 49, Issue 8, 2013, Pages 361-366

CpG island methylation of the MLH1, MGMT, DAPK, and CASP8 genes in cancerous and adjacent noncancerous stomach tissues

Author keywords

CASP8; DAPK; Methylation; MGMT; MLH1; Stomach cancer

Indexed keywords


EID: 84897652719     PISSN: 1010660X     EISSN: None     Source Type: Journal    
DOI: 10.3390/medicina49080056     Document Type: Article
Times cited : (20)

References (38)
  • 1
    • 33947313964 scopus 로고    scopus 로고
    • American Cancer Society.
    • Global cancer facts & figures. 2nd ed. Atlanta: American Cancer Society
    • American Cancer Society. Global cancer facts & figures. 2nd ed. Atlanta: American Cancer Society; 2011.
    • (2011)
  • 2
    • 33644757018 scopus 로고    scopus 로고
    • Alterations of tumor suppressor and tumor-related genes in the development and progression of gastric cancer.
    • Tamura G. Alterations of tumor suppressor and tumor-related genes in the development and progression of gastric cancer. World J Gastroenterol 2006;12:192-8.
    • (2006) World J Gastroenterol , vol.12 , pp. 192-198
    • Tamura, G.1
  • 3
    • 0142026042 scopus 로고    scopus 로고
    • Helicobacter pylori and gastric malignancies.
    • Nardone G, Morgner A. Helicobacter pylori and gastric malignancies. Helicobacter 2003;8 (1 Suppl):44-52.
    • (2003) Helicobacter , vol.8 , Issue.1 , pp. 44-52
    • Nardone, G.1    Morgner, A.2
  • 4
    • 0026583546 scopus 로고
    • Epstein-Barr virus-associated gastric adenocarcinoma
    • Shibata D, Weiss LM. Epstein-Barr virus-associated gastric adenocarcinoma. Am J Pathol 1992;140:769-74.
    • (1992) Am J Pathol , vol.140 , pp. 769-774
    • Shibata, D.1    Weiss, L.M.2
  • 6
    • 33744789155 scopus 로고    scopus 로고
    • CpG island methylation status in gastric carcinoma with and without infection of Epstein-Barr virus
    • Chang MS, Uozaki H, Chong JM, Ushiku T, Sakuma K, Ishikawa S, et al. CpG island methylation status in gastric carcinoma with and without infection of Epstein-Barr virus. Clin Cancer Res 2006;12:2995-3002.
    • (2006) Clin Cancer Res , vol.12 , pp. 2995-3002
    • Chang, M.S.1    Uozaki, H.2    Chong, J.M.3    Ushiku, T.4    Sakuma, K.5    Ishikawa, S.6
  • 7
    • 38149040758 scopus 로고    scopus 로고
    • CpG island hypermethylation of tumor-suppressor genes in H. pylori-infected non-neoplastic gastric mucosa is linked with gastric cancer risk.
    • Kaise M, Yamasaki T, Yonezawa J, Miwa J, Ohta Y, Tajiri H. CpG island hypermethylation of tumor-suppressor genes in H. pylori-infected non-neoplastic gastric mucosa is linked with gastric cancer risk. Helicobacter 2008;13:35-41.
    • (2008) Helicobacter , vol.13 , pp. 35-41
    • Kaise, M.1    Yamasaki, T.2    Yonezawa, J.3    Miwa, J.4    Ohta, Y.5    Tajiri, H.6
  • 8
    • 70349887752 scopus 로고    scopus 로고
    • Promoter hypermethylation of multiple genes in early gastric adenocarcinoma and precancerous lesions
    • Zou XP, Zhang B, Zhang XQ, Chen M, Cao J, Liu WJ. Promoter hypermethylation of multiple genes in early gastric adenocarcinoma and precancerous lesions. Hum Pathol 2009;40:1534-42.
    • (2009) Hum Pathol , vol.40 , pp. 1534-1542
    • Zou, X.P.1    Zhang, B.2    Zhang, X.Q.3    Chen, M.4    Cao, J.5    Liu, W.J.6
  • 10
    • 37349022478 scopus 로고    scopus 로고
    • Methylated TMS1 and DAPK genes predict prognosis and response to chemotherapy in gastric cancer
    • Kato K, Lida S, Uetake H, Takagi Y, Yamashita T, Inokuchi M, et al. Methylated TMS1 and DAPK genes predict prognosis and response to chemotherapy in gastric cancer. Int J Cancer 2008;122:603-8.
    • (2008) Int J Cancer , vol.122 , pp. 603-608
    • Kato, K.1    Lida, S.2    Uetake, H.3    Takagi, Y.4    Yamashita, T.5    Inokuchi, M.6
  • 11
    • 78651350836 scopus 로고    scopus 로고
    • Methylation of BNIP3 and DAPK indicates lower response to chemotherapy and poor prognosis in gastric cancer
    • Sugita H, Lida S, Inokuchi M, Kato K, Ishiguro M, Ishikawa T, et al. Methylation of BNIP3 and DAPK indicates lower response to chemotherapy and poor prognosis in gastric cancer. Oncol Rep 2011;25:513-8.
    • (2011) Oncol Rep , vol.25 , pp. 513-518
    • Sugita, H.1    Lida, S.2    Inokuchi, M.3    Kato, K.4    Ishiguro, M.5    Ishikawa, T.6
  • 12
    • 78049518932 scopus 로고    scopus 로고
    • Promoter DNA hypermethylation in gastric biopsies from subjects at high and low risk for gastric cancer
    • Schneider BG, Peng D, Camargo MC, Piazuelo MB, Sicinschi LA, Mera R, et al. Promoter DNA hypermethylation in gastric biopsies from subjects at high and low risk for gastric cancer. Int J Cancer 2010;127:2588-97.
    • (2010) Int J Cancer , vol.127 , pp. 2588-2597
    • Schneider, B.G.1    Peng, D.2    Camargo, M.C.3    Piazuelo, M.B.4    Sicinschi, L.A.5    Mera, R.6
  • 13
    • 0035575781 scopus 로고    scopus 로고
    • Methylation of O(6)-methylguanine-DNA methyltransferase gene is associated significantly with K-ras mutation, lymph node invasion, tumor staging, and disease free survival in patients with gastric carcinoma.
    • Park TJ, Han SU, Cho YK, Paik WK, Kim YB, Lim IK. Methylation of O(6)-methylguanine-DNA methyltransferase gene is associated significantly with K-ras mutation, lymph node invasion, tumor staging, and disease free survival in patients with gastric carcinoma. Cancer 2001;92: 2760-8.
    • (2001) Cancer , vol.92 , pp. 2760-2768
    • Park, T.J.1    Han, S.U.2    Cho, Y.K.3    Paik, W.K.4    Kim, Y.B.5    Lim, I.K.6
  • 14
    • 84863097904 scopus 로고    scopus 로고
    • Prognostic significance of aberrant gene methylation in gastric cancer
    • Shi J, Zhang G, Yao D, Liu W, Wang N, Ji M, et al. Prognostic significance of aberrant gene methylation in gastric cancer. Am J Cancer Res 2012;2:116-29.
    • (2012) Am J Cancer Res , vol.2 , pp. 116-129
    • Shi, J.1    Zhang, G.2    Yao, D.3    Liu, W.4    Wang, N.5    Ji, M.6
  • 15
    • 0037565368 scopus 로고    scopus 로고
    • Concurrent hypermethylation of gene promoters is associated with a MSI-H phenotype and diploidy in gastric carcinomas
    • Carvalho B, Pinto M, Cirnes L, Oleiveira C, Machado JC, Suriano G, et al. Concurrent hypermethylation of gene promoters is associated with a MSI-H phenotype and diploidy in gastric carcinomas. Eur J Cancer 2003;39:1222-7.
    • (2003) Eur J Cancer , vol.39 , pp. 1222-1227
    • Carvalho, B.1    Pinto, M.2    Cirnes, L.3    Oleiveira, C.4    Machado, J.C.5    Suriano, G.6
  • 16
    • 22644434527 scopus 로고    scopus 로고
    • Effects of dietary intake and genetic factors on hypermethylation of the hMLH1 gene promoter in gastric cancer
    • Nan HM, Song YJ, Yun HY, Park JS, Kim H. Effects of dietary intake and genetic factors on hypermethylation of the hMLH1 gene promoter in gastric cancer. World J Gastroenterol 2005;11:3834-41.
    • (2005) World J Gastroenterol , vol.11 , pp. 3834-3841
    • Nan, H.M.1    Song, Y.J.2    Yun, H.Y.3    Park, J.S.4    Kim, H.5
  • 17
    • 19944428803 scopus 로고    scopus 로고
    • Prognostic significance of CpG island methylator phenotype and microsatellite instability in gastric carcinoma
    • An C, Choi IS, Yao JC, Worah S, Xie K, Mansfield PF, et al. Prognostic significance of CpG island methylator phenotype and microsatellite instability in gastric carcinoma. Clin Cancer Res 2005;11:656-63.
    • (2005) Clin Cancer Res , vol.11 , pp. 656-663
    • An, C.1    Choi, I.S.2    Yao, J.C.3    Worah, S.4    Xie, K.5    Mansfield, P.F.6
  • 18
    • 3042679657 scopus 로고    scopus 로고
    • Frequent CpG island methylation in precursor lesions and early gastric adenocarcinomas
    • Lee JH, Park SJ, Abraham SC, Seo JS, Nam JH, Choi C, et al. Frequent CpG island methylation in precursor lesions and early gastric adenocarcinomas. Oncogene 2004;23:4646-54.
    • (2004) Oncogene , vol.23 , pp. 4646-4654
    • Lee, J.H.1    Park, S.J.2    Abraham, S.C.3    Seo, J.S.4    Nam, J.H.5    Choi, C.6
  • 19
    • 0034661742 scopus 로고    scopus 로고
    • Methylation of the hMLH1 promoter but no hMLH1 mutations in sporadic gastric carcinomas with high-level microsatellite instability
    • Bevilacqua RA, Simpson AJ. Methylation of the hMLH1 promoter but no hMLH1 mutations in sporadic gastric carcinomas with high-level microsatellite instability. Int J Cancer 2000;87:200-3.
    • (2000) Int J Cancer , vol.87 , pp. 200-203
    • Bevilacqua, R.A.1    Simpson, A.J.2
  • 20
    • 67651219459 scopus 로고    scopus 로고
    • Analysis of microsatellite instability, protein expression and methylation status of hMLH1 and hMSH2 genes in gastric carcinomas
    • Gu M, Kim D, Bae Y, Choi J, Kim S, Song S. Analysis of microsatellite instability, protein expression and methylation status of hMLH1 and hMSH2 genes in gastric carcinomas. Hepatogastroenterology 2009;56:899-904.
    • (2009) Hepatogastroenterology , vol.56 , pp. 899-904
    • Gu, M.1    Kim, D.2    Bae, Y.3    Choi, J.4    Kim, S.5    Song, S.6
  • 21
    • 0003412927 scopus 로고    scopus 로고
    • TNM classification of malignant tumors.
    • 6th ed. New York: Wiley-Blackwell
    • Sobin L. TNM classification of malignant tumors. 6th ed. New York: Wiley-Blackwell ; 2002.
    • (2002)
    • Sobin, L.1
  • 22
    • 0003443709 scopus 로고    scopus 로고
    • WHO classification of tumours pathology and genetics of tumours of digestive system.
    • Lyon: IARC
    • Hamilton SR, Aaltonen LA. WHO classification of tumours pathology and genetics of tumours of digestive system. Lyon: IARC; 2000.
    • (2000)
    • Hamilton, S.R.1    Aaltonen, L.A.2
  • 23
    • 12644292106 scopus 로고
    • The two histological main types of gastric carcinoma: diffuse and so called intestinal-type carcinoma. An attempt at a histoloclinical classification.
    • Lauren P. The two histological main types of gastric carcinoma: diffuse and so called intestinal-type carcinoma. An attempt at a histoloclinical classification. Acta Pathol Microbiol Scand 1965;64:31-49.
    • (1965) Acta Pathol Microbiol Scand , vol.64 , pp. 31-49
    • Lauren, P.1
  • 24
    • 0141537154 scopus 로고    scopus 로고
    • Aberrant CpG island hypermethylation of chronic gastritis, in relation to aging, gender, intestinal metaplasia, and chronic inflammation
    • Kang GH, Lee HJ, Hwang KS, Lee S, Kim JH, Kim JS. Aberrant CpG island hypermethylation of chronic gastritis, in relation to aging, gender, intestinal metaplasia, and chronic inflammation. Am J Pathol 2003;163:1551-6.
    • (2003) Am J Pathol , vol.163 , pp. 1551-1556
    • Kang, G.H.1    Lee, H.J.2    Hwang, K.S.3    Lee, S.4    Kim, J.H.5    Kim, J.S.6
  • 25
    • 2442535041 scopus 로고    scopus 로고
    • Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling
    • Lindsey JC, Lusher ME, Anderton JA, Bailey S, Gilbertson RJ, Pearson AD, et al. Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling. Carcinogenesis 2004;25:661-8.
    • (2004) Carcinogenesis , vol.25 , pp. 661-668
    • Lindsey, J.C.1    Lusher, M.E.2    Anderton, J.A.3    Bailey, S.4    Gilbertson, R.J.5    Pearson, A.D.6
  • 26
    • 55549133936 scopus 로고    scopus 로고
    • Distinct TPEF/HPP1 gene methylation patters in gastric cancer indicate a field effect in gastric carcinogenesis
    • Ivanauskas A, Hoffmann J, Jonaitis LV, Markelis R, Juozaityte E, Kupcinskas L, et al. Distinct TPEF/HPP1 gene methylation patters in gastric cancer indicate a field effect in gastric carcinogenesis. Dig Liver Dis 2008;40:920-6.
    • (2008) Dig Liver Dis , vol.40 , pp. 920-926
    • Ivanauskas, A.1    Hoffmann, J.2    Jonaitis, L.V.3    Markelis, R.4    Juozaityte, E.5    Kupcinskas, L.6
  • 27
    • 33846652476 scopus 로고    scopus 로고
    • An inverse correlation between interleukin-6 and select gene promoter methylation in patients with gastric cancer
    • Tang LP, Cho CH, Hui WM, Huang C, Chu KM, Xia HH, et al. An inverse correlation between interleukin-6 and select gene promoter methylation in patients with gastric cancer. Digestion 2006;74:85-90.
    • (2006) Digestion , vol.74 , pp. 85-90
    • Tang, L.P.1    Cho, C.H.2    Hui, W.M.3    Huang, C.4    Chu, K.M.5    Xia, H.H.6
  • 28
    • 67349124873 scopus 로고    scopus 로고
    • Biological significance of promoter hypermethylation of tumor-related genes in patients with gastric carcinoma
    • Ksiaa F, Ziadi S, Amara K, Korbi S, Trimeche M. Biological significance of promoter hypermethylation of tumor-related genes in patients with gastric carcinoma. Clinica Chimica Acta 2009;404:128-33.
    • (2009) Clinica Chimica Acta , vol.404 , pp. 128-133
    • Ksiaa, F.1    Ziadi, S.2    Amara, K.3    Korbi, S.4    Trimeche, M.5
  • 29
    • 77649241211 scopus 로고    scopus 로고
    • CpG island promoter methylation (CIHM) status of tumor suppressor genes correlates with morphological appearances of gastric cancer
    • Tahara T, Shibata T, Arisawa T, Nakamura M, Yamashita H, Yoshioka D, et al. CpG island promoter methylation (CIHM) status of tumor suppressor genes correlates with morphological appearances of gastric cancer. Anticancer Res 2010;30:239-44.
    • (2010) Anticancer Res , vol.30 , pp. 239-244
    • Tahara, T.1    Shibata, T.2    Arisawa, T.3    Nakamura, M.4    Yamashita, H.5    Yoshioka, D.6
  • 30
    • 84859422253 scopus 로고    scopus 로고
    • Epigenetic regulation of death-associated protein kinase expression in primary gastric cancers from Chinese patients
    • Ye M, Li D, Zhou F, Guo Q, Xia B. Epigenetic regulation of death-associated protein kinase expression in primary gastric cancers from Chinese patients. Eur J Cancer Prev 2012;21:241-6.
    • (2012) Eur J Cancer Prev , vol.21 , pp. 241-246
    • Ye, M.1    Li, D.2    Zhou, F.3    Guo, Q.4    Xia, B.5
  • 31
    • 79955482440 scopus 로고    scopus 로고
    • Hypermethylation of tumor-related genes in Tunisian patients with gastric carcinoma: clinical and biological significance
    • Ben Ayed-Guerfali D, Benhaj K, Khabir A, Abid M, Bayrouti MI, Sellami-Boudawara T, et al. Hypermethylation of tumor-related genes in Tunisian patients with gastric carcinoma: clinical and biological significance. J Surg Oncol 2011;103:687-94.
    • (2011) J Surg Oncol , vol.103 , pp. 687-694
    • Ben Ayed-Guerfali, D.1    Benhaj, K.2    Khabir, A.3    Abid, M.4    Bayrouti, M.I.5    Sellami-Boudawara, T.6
  • 32
    • 67349104826 scopus 로고    scopus 로고
    • Lack of death receptor 4 (DR4) expression through gene promoter methylation in gastric cancer
    • Lee KH, Lim SW, Kim HG, Kim DY, Ryu SY, Joo JK, et al. Lack of death receptor 4 (DR4) expression through gene promoter methylation in gastric cancer. Langenbecks Arch Surg 2009;394:661-70.
    • (2009) Langenbecks Arch Surg , vol.394 , pp. 661-670
    • Lee, K.H.1    Lim, S.W.2    Kim, H.G.3    Kim, D.Y.4    Ryu, S.Y.5    Joo, J.K.6
  • 34
    • 80052157951 scopus 로고    scopus 로고
    • Aberrant DNA methylation of cancer-associated genes in gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPICEURGAST)
    • Balassiano K, Lima S, Jenab M, Overvad K, Tjonneland A, Boutron-Ruault MC, et al. Aberrant DNA methylation of cancer-associated genes in gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPICEURGAST). Cancer Lett 2011;311:85-95.
    • (2011) Cancer Lett , vol.311 , pp. 85-95
    • Balassiano, K.1    Lima, S.2    Jenab, M.3    Overvad, K.4    Tjonneland, A.5    Boutron-Ruault, M.C.6
  • 35
    • 77952095889 scopus 로고    scopus 로고
    • Aberrant gene methylation in the lymph nodes provides a possible marker for diagnosing micrometastasis in gastric cancer
    • Hiraki M, Kitajima Y, Sato S, Mitsuno M, Koga Y, Nakamura J, et al. Aberrant gene methylation in the lymph nodes provides a possible marker for diagnosing micrometastasis in gastric cancer. Ann Surg Oncol 2010;17:1177-86.
    • (2010) Ann Surg Oncol , vol.17 , pp. 1177-1186
    • Hiraki, M.1    Kitajima, Y.2    Sato, S.3    Mitsuno, M.4    Koga, Y.5    Nakamura, J.6
  • 38
    • 0035724734 scopus 로고    scopus 로고
    • Promoter methylation status of the DNA repair genes hMLH1 and MGMT in gastric carcinoma and metaplastic mucosa
    • Oue N, Sentani K, Yokozaki H, Kitadai Y, Ito R, Yasui W. Promoter methylation status of the DNA repair genes hMLH1 and MGMT in gastric carcinoma and metaplastic mucosa. Pathobiology 2001;69:143-9.
    • (2001) Pathobiology , vol.69 , pp. 143-149
    • Oue, N.1    Sentani, K.2    Yokozaki, H.3    Kitadai, Y.4    Ito, R.5    Yasui, W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.