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Volumn 18, Issue 4, 2014, Pages 236-244

Telomere shortening: A biological marker of sporadic colorectal cancer with normal expression of p53 and mismatch repair proteins

Author keywords

[No Author keywords available]

Indexed keywords

MISMATCH REPAIR PROTEIN PMS2; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6; PROTEIN P53; TUMOR MARKER;

EID: 84897485600     PISSN: 19450265     EISSN: 19450257     Source Type: Journal    
DOI: 10.1089/gtmb.2013.0436     Document Type: Article
Times cited : (8)

References (41)
  • 2
    • 74049111326 scopus 로고    scopus 로고
    • Telomeres and telomerase in cancer
    • Artandi SE, DePinho RA (2010) Telomeres and telomerase in cancer. Carcinogenesis 31:9-18.
    • (2010) Carcinogenesis , vol.31 , pp. 9-18
    • Artandi, S.E.1    Depinho, R.A.2
  • 3
    • 76549104441 scopus 로고    scopus 로고
    • Evolution in health and medicine Sackler colloquium: Genetic variation in human telomerase is associated with telomere length in Ashkenazi centenarians
    • Atzmon G, Cho M, Cawthon RM, et al. (2010) Evolution in health and medicine Sackler colloquium: genetic variation in human telomerase is associated with telomere length in Ashkenazi centenarians. Proc Natl Acad Sci USA 107Suppl 1:1710-1717.
    • (2010) Proc Natl Acad Sci USA 107Suppl , vol.1 , pp. 1710-1717
    • Atzmon, G.1    Cho, M.2    Cawthon, R.M.3
  • 4
    • 33749631593 scopus 로고    scopus 로고
    • Telomeres: Prognostic markers for solid tumors
    • Bisoffi M, Heaphy CM, Griffith JK (2006) Telomeres: prognostic markers for solid tumors. Int J Cancer 119:2255-2260.
    • (2006) Int J Cancer , vol.119 , pp. 2255-2260
    • Bisoffi, M.1    Heaphy, C.M.2    Griffith, J.K.3
  • 5
    • 0025731583 scopus 로고
    • Structure and function of telomeres
    • Blackburn EH (1991) Structure and function of telomeres. Nature 350:569-573.
    • (1991) Nature , vol.350 , pp. 569-573
    • Blackburn, E.H.1
  • 6
    • 22944488871 scopus 로고    scopus 로고
    • Telomeres and human disease: Ageing, cancer and beyond
    • Blasco MA (2005) Telomeres and human disease: ageing, cancer and beyond. Nat Rev Genet 6:611-622.
    • (2005) Nat Rev Genet , vol.6 , pp. 611-622
    • Blasco, M.A.1
  • 7
    • 3042778750 scopus 로고    scopus 로고
    • Telomere length and human telomerase reverse transcriptase expression as markers for progression and prognosis of colorectal carcinoma
    • Gertler R, Rosenberg R, Stricker D, et al. (2004) Telomere length and human telomerase reverse transcriptase expression as markers for progression and prognosis of colorectal carcinoma. J Clin Oncol 22:1807-1814.
    • (2004) J Clin Oncol , vol.22 , pp. 1807-1814
    • Gertler, R.1    Rosenberg, R.2    Stricker, D.3
  • 8
    • 10044255290 scopus 로고    scopus 로고
    • Two colons-two cancers: Paradigm shift and clinical implications
    • Gervaz P, Bucher P, Morel P (2004) Two colons-two cancers: paradigm shift and clinical implications. J Surg Oncol 88:261-266.
    • (2004) J Surg Oncol , vol.88 , pp. 261-266
    • Gervaz, P.1    Bucher, P.2    Morel, P.3
  • 9
    • 0035940501 scopus 로고    scopus 로고
    • Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors
    • Gisselsson D, Jonson T, Petersen A, et al. (2001) Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors. Proc Natl Acad Sci USA 98:12683-12688.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 12683-12688
    • Gisselsson, D.1    Jonson, T.2    Petersen, A.3
  • 10
    • 84875046987 scopus 로고    scopus 로고
    • Genomics and proteomics approaches for biomarker discovery in sporadic colorectal cancer with metastasis
    • Gonzalez-Gonzalez M, Garcia JG, Montero JA, et al. (2013) Genomics and proteomics approaches for biomarker discovery in sporadic colorectal cancer with metastasis. Cancer Genomics Proteomics 10:19-25.
    • (2013) Cancer Genomics Proteomics , vol.10 , pp. 19-25
    • Gonzalez-Gonzalez, M.1    Garcia, J.G.2    Montero, J.A.3
  • 11
    • 53049087109 scopus 로고    scopus 로고
    • Genomic and epigenetic instability in colorectal cancer pathogenesis
    • Grady WM, Carethers JM (2008) Genomic and epigenetic instability in colorectal cancer pathogenesis. Gastroenterology 135:1079-1099.
    • (2008) Gastroenterology , vol.135 , pp. 1079-1099
    • Grady, W.M.1    Carethers, J.M.2
  • 12
    • 0038350026 scopus 로고    scopus 로고
    • Role of telomeres and telomerase in the pathogenesis of human cancer
    • Hahn WC (2003) Role of telomeres and telomerase in the pathogenesis of human cancer. J Clin Oncol 21:2034-2043.
    • (2003) J Clin Oncol , vol.21 , pp. 2034-2043
    • Hahn, W.C.1
  • 13
    • 0025787643 scopus 로고
    • Telomere loss: Mitotic clock or genetic time bomb?
    • Harley CB (1991) Telomere loss: mitotic clock or genetic time bomb? Mutat Res 256:271-282.
    • (1991) Mutat Res , vol.256 , pp. 271-282
    • Harley, C.B.1
  • 14
    • 39749163359 scopus 로고    scopus 로고
    • Telomerase and cancer therapeutics
    • Harley CB (2008) Telomerase and cancer therapeutics. Nat Rev Cancer 8:167-179.
    • (2008) Nat Rev Cancer , vol.8 , pp. 167-179
    • Harley, C.B.1
  • 15
    • 0025143252 scopus 로고
    • Telomere reduction in human colorectal carcinoma and with ageing
    • Hastie ND, Dempster M, Dunlop MG, et al. (1990) Telomere reduction in human colorectal carcinoma and with ageing. Nature 346:866-868.
    • (1990) Nature , vol.346 , pp. 866-868
    • Hastie, N.D.1    Dempster, M.2    Dunlop, M.G.3
  • 16
    • 37249062107 scopus 로고    scopus 로고
    • Telomere DNA content predicts breast cancer-free survival interval
    • Heaphy CM, Baumgartner KB, Bisoffi M, et al. (2007) Telomere DNA content predicts breast cancer-free survival interval. Clin Cancer Res 13:7037-7043.
    • (2007) Clin Cancer Res , vol.13 , pp. 7037-7043
    • Heaphy, C.M.1    Baumgartner, K.B.2    Bisoffi, M.3
  • 17
    • 0037057510 scopus 로고    scopus 로고
    • Are there two sides to colorectal cancer?
    • Iacopetta B (2002) Are there two sides to colorectal cancer? Int J Cancer 101:403-408.
    • (2002) Int J Cancer , vol.101 , pp. 403-408
    • Iacopetta, B.1
  • 18
    • 84863538955 scopus 로고    scopus 로고
    • Serrated lesions of the colorectum, a new entity: What should a clinician/endoscopist know about it?
    • Jouret-Mourin A, Geboes K (2012) Serrated lesions of the colorectum, a new entity: what should a clinician/endoscopist know about it? Acta Gastroenterol Belg 75:197-202.
    • (2012) Acta Gastroenterol Belg , vol.75 , pp. 197-202
    • Jouret-Mourin, A.1    Geboes, K.2
  • 19
    • 4344698133 scopus 로고    scopus 로고
    • Defective mismatchrepair colorectal cancer: Clinicopathologic characteristics and usefulness of immunohistochemical analysis for diagnosis
    • Jover R, Paya A, Alenda C, et al. (2004) Defective mismatchrepair colorectal cancer: clinicopathologic characteristics and usefulness of immunohistochemical analysis for diagnosis. Am J Clin Pathol 122:389-394.
    • (2004) Am J Clin Pathol , vol.122 , pp. 389-394
    • Jover, R.1    Paya, A.2    Alenda, C.3
  • 20
    • 0033034623 scopus 로고    scopus 로고
    • Clinical usefulness of telomerase activity and telomere length in the preoperative diagnosis of gastric and colorectal cancer
    • Katayama S, Shiota G, Oshimura M, Kawasaki H (1999) Clinical usefulness of telomerase activity and telomere length in the preoperative diagnosis of gastric and colorectal cancer. J Cancer Res Clin Oncol 125:405-410.
    • (1999) J Cancer Res Clin Oncol , vol.125 , pp. 405-410
    • Katayama, S.1    Shiota, G.2    Oshimura, M.3    Kawasaki, H.4
  • 21
    • 0027402360 scopus 로고
    • Malignant polyps: Are they sheep in wolves' clothing?
    • Koretz RL (1993) Malignant polyps: are they sheep in wolves' clothing? Ann Intern Med 118:63-68.
    • (1993) Ann Intern Med , vol.118 , pp. 63-68
    • Koretz, R.L.1
  • 22
    • 30944443562 scopus 로고    scopus 로고
    • The telomere length dynamic and methods of its assessment
    • Lin KW, Yan J (2005) The telomere length dynamic and methods of its assessment. J Cell Mol Med 9:977-989.
    • (2005) J Cell Mol Med , vol.9 , pp. 977-989
    • Lin, K.W.1    Yan, J.2
  • 23
    • 23944480315 scopus 로고    scopus 로고
    • Tumor-specific changes in mtDNA content in human cancer
    • Mambo E, Chatterjee A, Xing M, et al. (2005) Tumor-specific changes in mtDNA content in human cancer. Int J Cancer 116:920-924.
    • (2005) Int J Cancer , vol.116 , pp. 920-924
    • Mambo, E.1    Chatterjee, A.2    Xing, M.3
  • 24
    • 1242338876 scopus 로고    scopus 로고
    • Telomere shortening occurs in subsets of normal breast epithelium as well as in situ and invasive carcinoma
    • Meeker AK, Hicks JL, Gabrielson E, et al. (2004) Telomere shortening occurs in subsets of normal breast epithelium as well as in situ and invasive carcinoma. Am J Pathol 164:925-935.
    • (2004) Am J Pathol , vol.164 , pp. 925-935
    • Meeker, A.K.1    Hicks, J.L.2    Gabrielson, E.3
  • 25
    • 67649476101 scopus 로고    scopus 로고
    • Four novel germline mutations in the MLH1 and PMS2 mismatch repair genes in patients with hereditary nonpolyposis colorectal cancer
    • Montazer Haghighi M, Radpour R, Aghajani K, et al. (2009) Four novel germline mutations in the MLH1 and PMS2 mismatch repair genes in patients with hereditary nonpolyposis colorectal cancer. Int J Colorectal Dis 24:885-893.
    • (2009) Int J Colorectal Dis , vol.24 , pp. 885-893
    • Montazer Haghighi, M.1    Radpour, R.2    Aghajani, K.3
  • 26
    • 84871749525 scopus 로고    scopus 로고
    • Mechanisms of telomere loss and their consequences for chromosome instability
    • Muraki K, Nyhan K, Han L, Murnane JP (2012) Mechanisms of telomere loss and their consequences for chromosome instability. Front Oncol 2:135.
    • (2012) Front Oncol , vol.2 , pp. 135
    • Muraki, K.1    Nyhan, K.2    Han, L.3    Murnane, J.P.4
  • 27
    • 33645501130 scopus 로고    scopus 로고
    • Telomere length in the colon declines with age: A relation to colorectal cancer?
    • O'Sullivan J, Risques RA, Mandelson MT, et al. (2006) Telomere length in the colon declines with age: a relation to colorectal cancer? Cancer Epidemiol Biomarkers Prev 15:573-577.
    • (2006) Cancer Epidemiol Biomarkers Prev , vol.15 , pp. 573-577
    • O'Sullivan, J.1    Risques, R.A.2    Mandelson, M.T.3
  • 28
    • 37149041833 scopus 로고    scopus 로고
    • Molecular classification and correlates in colorectal cancer
    • Ogino S, Goel A (2008) Molecular classification and correlates in colorectal cancer. J Mol Diagn 10:13-27.
    • (2008) J Mol Diagn , vol.10 , pp. 13-27
    • Ogino, S.1    Goel, A.2
  • 29
    • 77952009891 scopus 로고    scopus 로고
    • Correlation of telomere length shortening with promoter methylation profile of p16/Rb and p53/p21 pathways in breast cancer
    • Radpour R, Barekati Z, Haghighi MM, et al. (2010) Correlation of telomere length shortening with promoter methylation profile of p16/Rb and p53/p21 pathways in breast cancer. Mod Pathol 23:763-772.
    • (2010) Mod Pathol , vol.23 , pp. 763-772
    • Radpour, R.1    Barekati, Z.2    Haghighi, M.M.3
  • 30
    • 74049103734 scopus 로고    scopus 로고
    • New trends in molecular biomarker discovery for breast cancer
    • Radpour R, Barekati Z, Kohler C, et al. (2009) New trends in molecular biomarker discovery for breast cancer. Genet Test Mol Biomarkers 13:565-571.
    • (2009) Genet Test Mol Biomarkers , vol.13 , pp. 565-571
    • Radpour, R.1    Barekati, Z.2    Kohler, C.3
  • 31
    • 56449090826 scopus 로고    scopus 로고
    • Highthroughput hacking of the methylation patterns in breast cancer by in vitro transcription and thymidine-specific cleavage mass array on MALDI-TOF silico-chip
    • Radpour R, Haghighi MM, Fan AX, et al. (2008) Highthroughput hacking of the methylation patterns in breast cancer by in vitro transcription and thymidine-specific cleavage mass array on MALDI-TOF silico-chip. Mol Cancer Res 6:1702-1709.
    • (2008) Mol Cancer Res , vol.6 , pp. 1702-1709
    • Radpour, R.1    Haghighi, M.M.2    Fan, A.X.3
  • 32
    • 54949084685 scopus 로고    scopus 로고
    • Telomere shortening is correlated with the DNA damage response and telomeric protein down-regulation in colorectal preneoplastic lesions
    • Raynaud CM, Jang SJ, Nuciforo P, et al. (2008) Telomere shortening is correlated with the DNA damage response and telomeric protein down-regulation in colorectal preneoplastic lesions. Ann Oncol 19:1875-1881.
    • (2008) Ann Oncol , vol.19 , pp. 1875-1881
    • Raynaud, C.M.1    Jang, S.J.2    Nuciforo, P.3
  • 33
    • 0033208626 scopus 로고    scopus 로고
    • Changes of telomerase and telomere lengths in paired normal and cancer tissues of breast
    • Rha SY, Park KH, Kim TS, et al. (1999) Changes of telomerase and telomere lengths in paired normal and cancer tissues of breast. Int J Oncol 15:839-845.
    • (1999) Int J Oncol , vol.15 , pp. 839-845
    • Rha, S.Y.1    Park, K.H.2    Kim, T.S.3
  • 34
    • 84865761205 scopus 로고    scopus 로고
    • Clinical end points for developing pharmaceuticals to manage patients with a sporadic or genetic risk of colorectal cancer
    • Rial NS, Zell JA, Cohen AM, Gerner EW (2012) Clinical end points for developing pharmaceuticals to manage patients with a sporadic or genetic risk of colorectal cancer. Expert Rev Gastroenterol Hepatol 6:507-517.
    • (2012) Expert Rev Gastroenterol Hepatol , vol.6 , pp. 507-517
    • Rial, N.S.1    Zell, J.A.2    Cohen, A.M.3    Gerner, E.W.4
  • 35
    • 0037316266 scopus 로고    scopus 로고
    • Assessment of telomere length and factors that contribute to its stability
    • Saldanha SN, Andrews LG, Tollefsbol TO (2003) Assessment of telomere length and factors that contribute to its stability. Eur J Biochem 270:389-403.
    • (2003) Eur J Biochem , vol.270 , pp. 389-403
    • Saldanha, S.N.1    Andrews, L.G.2    Tollefsbol, T.O.3
  • 36
    • 0036898005 scopus 로고    scopus 로고
    • Effect of fixatives and tissue processing on the content and integrity of nucleic acids
    • Srinivasan M, Sedmak D, Jewell S (2002) Effect of fixatives and tissue processing on the content and integrity of nucleic acids. Am J Pathol 161:1961-1971.
    • (2002) Am J Pathol , vol.161 , pp. 1961-1971
    • Srinivasan, M.1    Sedmak, D.2    Jewell, S.3
  • 37
    • 0033569955 scopus 로고    scopus 로고
    • Telomere shortening and the clinicopathologic characteristics of human colorectal carcinomas
    • Takagi S, Kinouchi Y, Hiwatashi N, et al. (1999) Telomere shortening and the clinicopathologic characteristics of human colorectal carcinomas. Cancer 86:1431-1436.
    • (1999) Cancer , vol.86 , pp. 1431-1436
    • Takagi, S.1    Kinouchi, Y.2    Hiwatashi, N.3
  • 38
    • 58149352913 scopus 로고    scopus 로고
    • Relationship between tumor and plasma levels of hTERT mRNA in patients with colorectal cancer: Implications for monitoring of neoplastic disease
    • Terrin L, Rampazzo E, Pucciarelli S, et al. (2008) Relationship between tumor and plasma levels of hTERT mRNA in patients with colorectal cancer: implications for monitoring of neoplastic disease. Clin Cancer Res 14:7444-7451.
    • (2008) Clin Cancer Res , vol.14 , pp. 7444-7451
    • Terrin, L.1    Rampazzo, E.2    Pucciarelli, S.3
  • 39
    • 46349086833 scopus 로고    scopus 로고
    • Association between chromosomal instability and prognosis in colorectal cancer: A meta-analysis
    • Walther A, Houlston R, Tomlinson I (2008) Association between chromosomal instability and prognosis in colorectal cancer: a meta-analysis. Gut 57:941-950.
    • (2008) Gut , vol.57 , pp. 941-950
    • Walther, A.1    Houlston, R.2    Tomlinson, I.3
  • 40
    • 0033834247 scopus 로고    scopus 로고
    • Telomere dynamics in cancer progression and prevention: Fundamental differences in human and mouse telomere biology
    • Wright WE, Shay JW (2000) Telomere dynamics in cancer progression and prevention: fundamental differences in human and mouse telomere biology. Nat Med 6:849-851.
    • (2000) Nat Med , vol.6 , pp. 849-851
    • Wright, W.E.1    Shay, J.W.2
  • 41
    • 6044230706 scopus 로고    scopus 로고
    • Telomere attrition predominantly occurs in precursor lesions during in vivo carcinogenic process of the uterine cervix
    • Zhang A, Wang J, Zheng B, et al. (2004) Telomere attrition predominantly occurs in precursor lesions during in vivo carcinogenic process of the uterine cervix. Oncogene 23: 7441-7447.
    • (2004) Oncogene , vol.23 , pp. 7441-7447
    • Zhang, A.1    Wang, J.2    Zheng, B.3


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