Genotoxicity assessment of magnetic iron oxide nanoparticles with different particle sizes and surface coatings

Nanotechnology

Volumn 25, Issue 42, 2014, Pages

  Liu, Yanping ^a   Xia, Qiyue ^a   Liu, Ying ^a   Zhang, Shuyang ^a   Cheng, Feng ^a   Zhong, Zhihui ^a   Wang, Li ^a   Li, Hongxia ^a   Xiao, Kai ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

bacterial reverse mutation test; chromosome aberration test; genotoxicity; iron oxide nanoparticles; micronucleus test; particle size; surface coating

Indexed keywords

BACTERIAL REVERSE MUTATION TESTS; CHROMOSOME ABERRATION TESTS; GENOTOXICITIES; IRON OXIDE NANOPARTICLE; MICRONUCLEUS TEST; SURFACE COATINGS;

PARTICLE SIZE;

FERRIC ION; FERRIC OXIDE; METAL NANOPARTICLE;

ANIMAL; CELL LINE; CHEMICALLY INDUCED; CHEMISTRY; CHROMOSOME ABERRATION; CRICETULUS; DRUG EFFECTS; ERYTHROCYTE; GENETICS; MALE; METABOLISM; MOUSE; MUTAGEN TESTING; PARTICLE SIZE; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM; SPRAGUE DAWLEY RAT;

ANIMALS; CELL LINE; CHROMOSOME ABERRATIONS; CRICETULUS; ERYTHROCYTES; FERRIC COMPOUNDS; MALE; METAL NANOPARTICLES; MICE; MUTAGENICITY TESTS; PARTICLE SIZE; RATS, SPRAGUE-DAWLEY; SALMONELLA TYPHIMURIUM;

EID: 84907736120     PISSN: 09574484     EISSN: 13616528     Source Type: Journal    
DOI: 10.1088/0957-4484/25/42/425101     Document Type: Article

References (57)

1. Singh N, Manshian B, Jenkins G J, Griffiths S M, Williams P M, Maffeis T G, Wright C J and Doak S H 2009 NanoGenotoxicology: the DNA damaging potential of engineered nanomaterials Biomaterials 30 3891-914
2. Gomaa I O, Kader M H, Salah T A and Heikal O A 2013 Evaluation of in vitro mutagenicity and genotoxicity of magnetite Nanoparticles Drug Discov. Ther. 7 116-23
3. Naqvi S, Samim M, Abdin M, Ahmed F J, Maitra A, Prashant C and Dinda A K 2010 Concentration-dependent toxicity of iron oxide nanoparticles mediated by increased oxidative stress Int. J. Nanomedicine 5 983-9
4. Szalay B, Tátrai E, Nyír G, Vezér T and Dura G 2012 Potential toxic effects of iron oxide nanoparticles in in vivo and in vitro experiments J. Appl. Toxicol. 32 446-53
5. Sahu S C and Casciano D A 2009 Nanotoxicity: From In Vivo and In Vitro Models to Health Risks (UK: Wiley)
6. Sadiq R, Khan Q M, Mobeen A and Hashmat A J 2014 In vitro toxicological assessment of iron oxide, aluminium oxide and copper nanoparticles in prokaryotic and eukaryotic cell types Drug Chem. Toxicol. [Epub ahead of print]
7. Woodruff R S, Li Y, Yan J, Bishop M, Jones M Y, Watanabe F, Biris A S, Rice P, Zhou T and Chen T 2012 Genotoxicity evaluation of titanium dioxide nanoparticles using the Ames test and Comet assay J. Appl. Toxicol. 32 934-43
8. Alexis F, Pridgen E, Molnar L K and Farokhzad O C 2008 Factors affecting the clearance and biodistribution of polymeric nanoparticles Mol. Pharm. 5 505-15
9. Xiao K, Li Y, Luo J, Lee J S, Xiao W, Gonik A M, Agarwal R G and Lam K S 2011 The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles Biomaterials 32 3435-46
10. Xiao K, Luo J, Fowler W L, Li Y, Lee J S, Xing L, Cheng R H, Wang L and Lam K S 2009 A self-assembling nanoparticle for paclitaxel delivery in ovarian cancer Biomaterials 30 6006-16
11. Elliott B M, Combes R D, Elcombe C R, Gatehouse D G, Gibson G G, Mackay J M and Wolf R C 1992 Alternatives to aroclor 1254-induced S9 in in vitro genotoxicity assays Mutagenesis 7 175-7
12. OECD (Organization for Economic Cooperation and Development) 1997 Guideline 471 Guideline for the Testing of Chemicals: Bacteria Reverse Mutation Testwww.oecd.org/chemicalsafety/risk-assessment/1948418.pdf (Adopted 21st July, 1997)
13. Ames B N, Durston W E, Yamasaki E and Lee F D 1973 Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection Proc. Natl. Acad. Sci. USA 70 2281-5
14. Maron D M and Ames B N 1983 Revised methods for the Salmonella mutagenicity test Mutat. Res. 113 173-215
15. Ames B N, McCann J and Yamasaki E 1975 Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test Mutat. Res. 31 347-64
16. OECD (Organization for Economic Cooperation and Development) 1997 Guideline 473 Guideline for the Testing of Chemicals: In vitro Mammalian Chromosome Aberration Testwww.oecd.org/chemicalsafety/risk-assessment/1948442.pdf (Adopted 21st July, 1997)
17. Maenosono S, Yoshida R and Saita S 2009 Evaluation of genotoxicity of amine-terminated water-dispersible FePt nanoparticles in the Ames test and in vitro chromosomal aberration test J. Toxicol. Sci. 34 349-54
18. OECD (Organization for Economic Cooperation and Development) 1997 Guideline 474 Guideline for the Testing of Chemicals: Mammalian Erythrocyte Micronucleus Testwww.oecd.org/chemicalsafety/risk-assessment/1948442.pdf (Adopted 21st July, 1997)
19. Trouiller B, Reliene R, Westbrook A, Solaimani P and Schiestl R H 2009 Titanium dioxide nanoparticles induce DNA damage and genetic instability in vivo in mice Cancer Res. 69 8784-9
20. Maenosono S, Suzuki T and Saita S 2007 Mutagenicity of water-soluble FePt nanoparticles in Ames test J. Toxicol. Sci. 32 575-9
21. Kumar A, Pandey A K, Singh S S, Shanker R and Dhawan A 2011 Cellular uptake and mutagenic potential of metal oxide nanoparticles in bacterial cells Chemosphere 83 1124-32
22. Sereemaspun A, Hongpiticharoen P, Rojanathanes R, Maneewattanapinyo P, Ekgasit S and Warisnoicharoen W 2008 Inhibition of human cytochrome P450 enzymes by metallic nanoparticles: a preliminary to nanogenomics Int. J. Pharmacol. 4 492-5
23. Romberg B, Hennink W E and Storm G 2008 Sheddable coatings for long-circulating nanoparticles Pharm. Res. 25 55-71
24. Sharifi S, Behzadi S, Laurent S, Forrest M L, Stroeve P and Mahmoudi M 2012 Toxicity of nanomaterials Chem. Soc. Rev. 41 2323-43
25. Song Y, Li X and Du X 2009 Exposure to nanoparticles is related to pleural effusion, pulmonary fibrosis and granuloma Eur. Respir. J. 34 559-67
26. Kreuter J 2007 Nanoparticles - a historical perspective Int. J. Pharm. 331 1-10
27. Lherm C, Müller R H, Puisieux F and Couvreur P 1992 Alkylcyanoacrylate drug carriers: II. Cytotoxicity of cyanoacrylate nanoparticles with different alkyl chain length Int. J. Pharm 84 13-22
28. Aillon K L, Xie Y, El-Gendy N, Berkland C J and Forrest M L 2009 Effects of nanomaterial physicochemical properties on in vivo toxicity Adv. Drug Delivery Rev. 61 457-66
29. Lanone S and Boczkowski J 2006 Biomedical applications and potential health risks of nanomaterials: molecular mechanisms Curr. Mol. Med. 6 651-63
30. Nel A, Xia T, Mädler L and Li N 2006 Toxic potential of materials at the nanolevel Science 311 622-7
31. Rejman J, Oberle V, Zuhorn I S and Hoekstra D 2004 Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis Biochem. J. 377 159-69
32. Powers K W, Brown S C, Krishna V B, Wasdo S C, Moudgil B M and Roberts S M 2006 Research strategies for safety evaluation of nanomaterials. VI. Characterization of nanoscale particles for toxicological evaluation Toxicol. Sci. 90 296-303
33. Powers K W, Palazuelos M, Moudgil B M and Roberts S M 2007 Characterization of the size, shape, and state of dispersion of nanoparticles for toxicological studies Nanotoxicology 1 42-51
34. Guan R, Kang T, Lu F, Zhang Z, Shen H and Liu M 2012 Cytotoxicity, oxidative stress, and genotoxicity in human hepatocyte and embryonic kidney cells exposed to ZnO nanoparticles Nanoscale Res. Lett. 7 602
35. Hunter A C and Moghimi S M 2010 Cationic carriers of genetic material and cell death: a mitochondrial tale Biochim. Biophys. Acta 1797 1203-9
36. Klien K and Gondić-Cvar J 2012 Genotoxicity of metal nanoparticles: focus on in vivo studies Arh Hig Rada Toksikol 63 133-45
37. Singh R, Pantarotto D, Lacerda L, Pastorin G, Klumpp C, Prato M, Bianco A and Kostarelos K 2006 Tissue biodistribution and blood clearance rates of intravenously administered carbon nanotube radiotracers Proc. Natl. Acad. Sci. USA 103 3357-62
38. Deng X, Jia G, Wang H, Sun H, Wang X, Yang S, Wang T and Liu Y 2007 Translocation and fate of multi-walled carbon nanotubes In Vivo Carbon 45 1419-24
39. Schulze E, Ferrucci J T Jr, Poss K, Lapointe L, Bogdanova A and Weissleder R 1995 Cellular uptake and trafficking of a prototypical magnetic iron oxide label in vitro Invest. Radiol. 30 604-10
40. Berry C C, Wells S, Charles S and Curtis A S 2003 Dextran and albumin derivatised iron oxide nanoparticles: influence on fibroblasts in vitro Biomaterials 24 4551-7
41. Xie J, Xu C, Kohler N, Hou Y and Sun S 2007 Controlled PEGylation of monodisperse Fe3O4 nanoparticles for reduced non-specific uptake by macrophage cells Adv. Mater. 19 3163-6
42. Cho W S, Cho M, Jeong J, Choi M, Cho H Y, Han B S, Kim S H, Kim H O, Lim Y T, Chung B H and Jeong J 2009 Acute toxicity and pharmacokinetics of 13 nm-sized PEG-coated gold nanoparticles Toxicol. Appl. Pharmacol. 236 16-24
43. Hu Y, Xie J, Tong Y W and Wang C H 2007 Effect of PEG conformation and particle size on the cellular uptake efficiency of nanoparticles with the HepG2 cells J. Control. Release 118 7-17
44. Ahamed M, Karns M, Goodson M, Rowe J, Hussain S M, Schlager J J and Hong Y 2008 DNA damage response to different surface chemistry of silver nanoparticles in mammalian cells Toxicol. Appl. Pharmacol. 233 404-10
45. Ahamed M, Posgai R, Gorey T J, Nielsen M, Hussain S M and Rowe J J 2010 Silver nanoparticles induced heat shock protein 70, oxidative stress and apoptosis in Drosophila melanogaster Toxicol. Appl. Pharmacol. 242 263-9
46. Hwang do W, Lee D S and Kim S 2012 Gene expression profiles for genotoxic effects of silica-free and silica-coated cobalt ferrite nanoparticles J. Nucl. Med. 53 106-12
47. Hoshino A, Fujioka K, Oku T, Suga M, Sasaki Y F, Ohta T, Yasuhara M, Suzuki K and Yamamoto K 2004 Physicochemical properties and cellular toxicity of nanocrystal quantum dots depend on their surface modification Nano. Lett. 4 2163-9
48. Goodman C M, McCusker C D, Yilmaz T and Rotello V M 2004 Toxicity of gold nanoparticles functionalized with cationic and anionic side chains Bioconjug. Chem. 15 897-900
49. Saxena R K, Williams W, Mcgee J K, Daniels M J, Boykin E and Ian Gilmour M 2007 Enhanced in vitro and in vivo toxicity of poly-dispersed acid-functionalized single-wall carbon nanotubes Nanotoxicology 1 291-300
50. Pietroiusti A, Massimiani M, Fenoglio I, Colonna M, Valentini F, Palleschi G, Camaioni A, Magrini A, Siracusa G, Bergamaschi A, Sgambato A and Campagnolo L 2011 Low doses of pristine and oxidized single-wall carbon nanotubes affect mammalian embryonic development ACS Nano 5 4624-33
51. Kim S, Fisher B, Eisler H J and Bawendi M 2003 Type-II quantum dots: CdTe/CdSe(core/shell) and CdSe/ZnTe(core/shell) heterostructures J. Am. Chem. Soc. 125 11466-7
52. Geys J, Nemmar A, Verbeken E, Smolders E, Ratoi M, Hoylaerts M F, Nemery B and Hoet P H 2008 Acute toxicity and prothrombotic effects of quantum dots: impact of surface charge Environ. Health Perspect. 116 1607-13
53. Bhattacharjee S, de Haan L H, Evers N M, Jiang X, Marcelis A T, Zuilhof H, Rietjens I M and Alink G M 2010 Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells Part. Fibre Toxicol. 7 25
54. Heiden T C, Dengler E, Kao W J, Heideman W and Peterson R E 2007 Developmental toxicity of low generation PAMAM dendrimers in zebrafish Toxicol. Appl. Pharmacol. 225 70-9
55. Malik N, Evagorou E G and Duncan R 1999 Dendrimer-platinate: a novel approach to cancer chemotherapy Anticancer Drugs 10 767-76
56. Lockman P R, Koziara J M, Mumper R J and Allen D D 2004 Nanoparticle surface charges alter blood-brain barrier integrity and permeability J. Drug Target 12 635-41
57. Ng C T, Li J J, Bay B H and Yung L Y 2010 Current studies into the genotoxic effects of nanomaterials J. Nucleic Acids 947859