Platelet 12-LOX is essential for FcγRIIa-mediated platelet activation

Blood

Volumn 124, Issue 14, 2014, Pages 2271-2279

  Yeung, Jennifer ^a   Tourdot, Benjamin E ^a   Fernandez Perez, Pilar ^a   Vesci, Joanne ^a   Ren, Jin ^a   Smyrniotis, Christopher J ^b   Luci, Diane K ^c   Jadhav, Ajit ^c   Simeonov, Anton ^c   Maloney, David J ^c   Holman, Theodore R ^b   McKenzie, Steven E ^a   Holinstat, Michael ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; ARACHIDONATE 12 LIPOXYGENASE; CALCIUM; FC RECEPTOR; FC RECEPTOR IIA; PHOSPHOLIPASE C GAMMA; PROTEIN KINASE C;

ANIMAL; C57BL MOUSE; CHEMISTRY; ENZYME ACTIVATION; HUMAN; IMMUNOLOGY; METABOLISM; MOUSE; PHOSPHORYLATION; SIGNAL TRANSDUCTION; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOSIS; TRANSGENIC MOUSE;

12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID; ANIMALS; ARACHIDONATE 12-LIPOXYGENASE; BLOOD PLATELETS; CALCIUM; ENZYME ACTIVATION; HUMANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PLATELET ACTIVATION; PLATELET AGGREGATION; PROTEIN KINASE C; RECEPTORS, IGG; SIGNAL TRANSDUCTION; THROMBOSIS;

EID: 84907708978     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-05-575878     Document Type: Article

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