-
1
-
-
58349109868
-
Incidence of retinoblastoma in the USA: 1975-2004
-
Broaddus E, Topham A and Singh AD: Incidence of retinoblastoma in the USA: 1975-2004. Br J Ophthalmol 93:21-23, 2009.
-
(2009)
Br J Ophthalmol
, vol.93
, pp. 21-23
-
-
Broaddus, E.1
Topham, A.2
Singh, A.D.3
-
3
-
-
0023815309
-
Incidence of second neoplasms in patients with bilateral retinoblastoma
-
Roarty JD, McLean IW and Zimmerman LE: Incidence of second neoplasms in patients with bilateral retinoblastoma. Ophthalmology 95:1583-1587, 1988.
-
(1988)
Ophthalmology
, vol.95
, pp. 1583-1587
-
-
Roarty, J.D.1
McLean, I.W.2
Zimmerman, L.E.3
-
4
-
-
28844433635
-
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
-
Shaw RJ, Lamia KA, Vasquez D, et al: The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. Science 310:1642-1646, 2005.
-
(2005)
Science
, vol.310
, pp. 1642-1646
-
-
Shaw, R.J.1
Lamia, K.A.2
Vasquez, D.3
-
5
-
-
84856838013
-
Success of intra-arterial chemotherapy (chemosurgery) for retinoblastoma: Effect of orbitovascular anatomy
-
Marr BP, Hung C, Gobin YP, Dunkel IJ, Brodie SE and Abramson DH: Success of intra-arterial chemotherapy (chemosurgery) for retinoblastoma: effect of orbitovascular anatomy. Arch Ophthalmol 130:180-185, 2012.
-
(2012)
Arch Ophthalmol
, vol.130
, pp. 180-185
-
-
Marr, B.P.1
Hung, C.2
Gobin, Y.P.3
Dunkel, I.J.4
Brodie, S.E.5
Abramson, D.H.6
-
6
-
-
84875278034
-
Metformin inhibits renal cell carcinoma in vitro and in vivo xenograft
-
Liu J, Li M, Song B, et al: Metformin inhibits renal cell carcinoma in vitro and in vivo xenograft. Urol Oncol 31:264-270, 2013.
-
(2013)
Urol Oncol
, vol.31
, pp. 264-270
-
-
Liu, J.1
Li, M.2
Song, B.3
-
7
-
-
84859269733
-
Fluorescein angiographic findings after intra-arterial chemotherapy for retinoblastoma
-
Bianciotto C, Shields CL, Iturralde JC, Sarici A, Jabbour P and Shields JA: Fluorescein angiographic findings after intra-arterial chemotherapy for retinoblastoma. Ophthalmology 119:843-849, 2012.
-
(2012)
Ophthalmology
, vol.119
, pp. 843-849
-
-
Bianciotto, C.1
Shields, C.L.2
Iturralde, J.C.3
Sarici, A.4
Jabbour, P.5
Shields, J.A.6
-
8
-
-
84857923529
-
Efficacy and complications of super-selective intra-ophthalmic artery melphalan for the treatment of refractory retinoblastoma
-
Muen WJ, Kingston JE, Robertson F, Brew S, Sagoo MS and Reddy MA: Efficacy and complications of super-selective intra-ophthalmic artery melphalan for the treatment of refractory retinoblastoma. Ophthalmology 119:611-616, 2012.
-
(2012)
Ophthalmology
, vol.119
, pp. 611-616
-
-
Muen, W.J.1
Kingston, J.E.2
Robertson, F.3
Brew, S.4
Sagoo, M.S.5
Reddy, M.A.6
-
9
-
-
33750614422
-
2.aminophenoxazine-3.one suppresses the growth of mouse malignant melanoma B16 cells transplanted into C57BL/6Cr Slc mice
-
Miyano-Kurosaki N, Kurosaki K, Hayashi M, et al: 2.aminophenoxazine-3.one suppresses the growth of mouse malignant melanoma B16 cells transplanted into C57BL/6Cr Slc mice. Biol Pharm Bull 29:2197-2201, 2006.
-
(2006)
Biol Pharm Bull
, vol.29
, pp. 2197-2201
-
-
Miyano-Kurosaki, N.1
Kurosaki, K.2
Hayashi, M.3
-
10
-
-
84867346156
-
Intravitreal melphalan for refractory or recurrent vitreous seeding from retinoblastoma
-
Ghassemi F and Shields CL: Intravitreal melphalan for refractory or recurrent vitreous seeding from retinoblastoma. Arch Ophthalmol 130:1268-1271, 2012.
-
(2012)
Arch Ophthalmol
, vol.130
, pp. 1268-1271
-
-
Ghassemi, F.1
Shields, C.L.2
-
11
-
-
84865131639
-
In vitro and in vivo antitumoral action of metformin on hepatocellular carcinoma
-
Qu Z, Zhang Y, Liao M, Chen Y, Zhao J and Pan Y: In vitro and in vivo antitumoral action of metformin on hepatocellular carcinoma. Hepatol Res 42:922-933, 2012.
-
(2012)
Hepatol Res
, vol.42
, pp. 922-933
-
-
Qu, Z.1
Zhang, Y.2
Liao, M.3
Chen, Y.4
Zhao, J.5
Pan, Y.6
-
12
-
-
84864831608
-
Intravitreal chemotherapy for vitreous disease in retinoblastoma revisited: From prohibition to conditional indications
-
Munier FL, Gaillard M-C, Balmer A, et al: Intravitreal chemotherapy for vitreous disease in retinoblastoma revisited: from prohibition to conditional indications. Br J Ophthalmol 96:1078-1083, 2012.
-
(2012)
Br J Ophthalmol
, vol.96
, pp. 1078-1083
-
-
Munier, F.L.1
Gaillard, M.-C.2
Balmer, A.3
-
13
-
-
0036300477
-
Factors predictive of recurrence of retinal tumors, vitreous seeds, and subretinal seeds following chemoreduction for retinoblastoma
-
Shields C L C, Honavar S G S, Shields J A J, Demirci HH, Meadows A T A and Naduvilath T J T: Factors predictive of recurrence of retinal tumors, vitreous seeds, and subretinal seeds following chemoreduction for retinoblastoma. Arch Ophthalmol 120:460-464, 2002.
-
(2002)
Arch Ophthalmol
, vol.120
, pp. 460-464
-
-
Shields, C.L.C.1
Honavar, S.G.S.2
Shields, J.A.J.3
Demirci, H.H.4
Meadows, A.T.A.5
Naduvilath, T.J.T.6
-
14
-
-
0242443398
-
Development of new retinoblastomas after 6 cycles of chemoreduction for retinoblastoma in 162 eyes of 106 consecutive patients
-
Shields CL, Shelil A, Cater J, Meadows AT and Shields JA: Development of new retinoblastomas after 6 cycles of chemoreduction for retinoblastoma in 162 eyes of 106 consecutive patients. Arch Ophthalmol 121:1571-1576, 2003.
-
(2003)
Arch Ophthalmol
, vol.121
, pp. 1571-1576
-
-
Shields, C.L.1
Shelil, A.2
Cater, J.3
Meadows, A.T.4
Shields, J.A.5
-
15
-
-
0037587764
-
Comparison of retinoblastoma reduction for chemotherapy vs external beam radiotherapy
-
Sussman DA, Escalona-Benz E, Benz MS, et al: Comparison of retinoblastoma reduction for chemotherapy vs external beam radiotherapy. Arch Ophthalmol 121:979-984, 2003.
-
(2003)
Arch Ophthalmol
, vol.121
, pp. 979-984
-
-
Sussman, D.A.1
Escalona-Benz, E.2
Benz, M.S.3
-
16
-
-
33845811091
-
Macular retinoblastoma: Evaluation of tumor control, local complications, and visual outcomes for eyes treated with chemotherapy and repetitive foveal laser ablation
-
Schefler AC, Cicciarelli N, Feuer W, Toledano S and Murray TG: Macular retinoblastoma: evaluation of tumor control, local complications, and visual outcomes for eyes treated with chemotherapy and repetitive foveal laser ablation. Opthalmology 114:162-169, 2007.
-
(2007)
Opthalmology
, vol.114
, pp. 162-169
-
-
Schefler, A.C.1
Cicciarelli, N.2
Feuer, W.3
Toledano, S.4
Murray, T.G.5
-
17
-
-
57649129028
-
Forget-me-nots in the care of children with retinoblastoma
-
Shields CL: Forget-me-nots in the care of children with retinoblastoma. Semin Ophthalmol 23:324-334, 2009.
-
(2009)
Semin Ophthalmol
, vol.23
, pp. 324-334
-
-
Shields, C.L.1
-
18
-
-
62449100167
-
Retinoblastoma regression patterns following chemoreduction and adjuvant therapy in 557 tumors
-
Shields CL, Palamar M, Sharma P, et al: Retinoblastoma regression patterns following chemoreduction and adjuvant therapy in 557 tumors. Arch Ophthalmol 127:282-290, 2009.
-
(2009)
Arch Ophthalmol
, vol.127
, pp. 282-290
-
-
Shields, C.L.1
Palamar, M.2
Sharma, P.3
-
19
-
-
0034113861
-
Complications of systemic chemotherapy as treatment of retinoblastoma
-
Benz MS, Scott IU, Murray TG, Kramer D and Toledano S: Complications of systemic chemotherapy as treatment of retinoblastoma. Arch Ophthalmol 118:577-578, 2000.
-
(2000)
Arch Ophthalmol
, vol.118
, pp. 577-578
-
-
Benz, M.S.1
Scott, I.U.2
Murray, T.G.3
Kramer, D.4
Toledano, S.5
-
20
-
-
0035503438
-
Acute myeloblastic leukemia as a second malignancy in a patient with hereditary retinoblastoma
-
Nishimura S, Sato T, Ueda H and Ueda K: Acute myeloblastic leukemia as a second malignancy in a patient with hereditary retinoblastoma. J Clin Oncol 19:4182-4183, 2001.
-
(2001)
J Clin Oncol
, vol.19
, pp. 4182-4183
-
-
Nishimura, S.1
Sato, T.2
Ueda, H.3
Ueda, K.4
-
21
-
-
0029133235
-
Metabolic effects of metformin in non-insulin-dependent diabetes mellitus
-
Stumvoll M, Nurjhan N, Perriello G, Dailey G and Gerich JE: Metabolic effects of metformin in non-insulin-dependent diabetes mellitus. N Engl J Med 333:550-554, 1995.
-
(1995)
N Engl J Med
, vol.333
, pp. 550-554
-
-
Stumvoll, M.1
Nurjhan, N.2
Perriello, G.3
Dailey, G.4
Gerich, J.E.5
-
22
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
Zhou G, Myers R, Li Y, et al: Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest 108:1167-1174, 2001.
-
(2001)
J Clin Invest
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
Myers, R.2
Li, Y.3
-
23
-
-
0026801474
-
Cellular mechanism of metformin action involves glucose transporter translocation from an intracellular pool to the plasma membrane in L6 muscle cells
-
Hundal HS, Ramlal T, Reyes R, Leiter LA and Klip A: Cellular mechanism of metformin action involves glucose transporter translocation from an intracellular pool to the plasma membrane in L6 muscle cells. Endocrinology 131:1165-1173, 1992.
-
(1992)
Endocrinology
, vol.131
, pp. 1165-1173
-
-
Hundal, H.S.1
Ramlal, T.2
Reyes, R.3
Leiter, L.A.4
Klip, A.5
-
24
-
-
44849099894
-
The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level
-
Sahra IB, Laurent K, Loubat A, et al: The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level. Oncogene 27:3576-3586, 2008.
-
(2008)
Oncogene
, vol.27
, pp. 3576-3586
-
-
Sahra, I.B.1
Laurent, K.2
Loubat, A.3
-
25
-
-
34547114031
-
Systemic treatment with the antidiabetic drug metformin selectively impairs p53.deficient tumor cell growth
-
Buzzai M, Jones RG, Amaravadi RK, et al: Systemic treatment with the antidiabetic drug metformin selectively impairs p53.deficient tumor cell growth. Cancer Res 67:6745-6752, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 6745-6752
-
-
Buzzai, M.1
Jones, R.G.2
Amaravadi, R.K.3
-
27
-
-
80053417028
-
Metformin inhibits melanoma development through autophagy and apoptosis mechanisms
-
Tomic T, Botton T, Cerezo M, et al: Metformin inhibits melanoma development through autophagy and apoptosis mechanisms. Cell Death Dis 2: e199, 2011.
-
(2011)
Cell Death Dis
, vol.2
, pp. e199
-
-
Tomic, T.1
Botton, T.2
Cerezo, M.3
-
28
-
-
84859386824
-
The antidiabetic drug metformin inhibits gastric cancer cell proliferation in vitro and in vivo
-
Kato K, Gong J, Iwama H, et al: The antidiabetic drug metformin inhibits gastric cancer cell proliferation in vitro and in vivo. Mol Cancer Ther 11:549-560, 2012.
-
(2012)
Mol Cancer Ther
, vol.11
, pp. 549-560
-
-
Kato, K.1
Gong, J.2
Iwama, H.3
-
29
-
-
84864059240
-
Metformin accelerates the growth of BRAF V600E-driven melanoma by upregulating VEGF-A
-
Martin MJ, Hayward R, Viros A and Marais R: Metformin accelerates the growth of BRAF V600E-driven melanoma by upregulating VEGF-A. Cancer Discov 2:344-355, 2012.
-
(2012)
Cancer Discov
, vol.2
, pp. 344-355
-
-
Martin, M.J.1
Hayward, R.2
Viros, A.3
Marais, R.4
-
30
-
-
58149156184
-
Therapeutic metformin/AMPK activation promotes the angiogenic phenotype in the ERalpha negative MDA-MB-435 breast cancer model
-
Phoenix KN, Vumbaca F and Claffey KP: Therapeutic metformin/AMPK activation promotes the angiogenic phenotype in the ERalpha negative MDA-MB-435 breast cancer model. Breast Cancer Res Treat 113:101-111, 2009.
-
(2009)
Breast Cancer Res Treat
, vol.113
, pp. 101-111
-
-
Phoenix, K.N.1
Vumbaca, F.2
Claffey, K.P.3
-
31
-
-
33751284806
-
Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells
-
Zakikhani M, Dowling R, Fantus IG, Sonenberg N and Pollak M: Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells. Cancer Res 66:10269-10273, 2006.
-
(2006)
Cancer Res
, vol.66
, pp. 10269-10273
-
-
Zakikhani, M.1
Dowling, R.2
Fantus, I.G.3
Sonenberg, N.4
Pollak, M.5
-
32
-
-
58149354390
-
Cell cycle arrest in metformin treated breast cancer cells involves activation of AMPK, downregulation of cyclin D1, and requires p27Kip1 or p21Cip1
-
Zhuang Y and Miskimins WK: Cell cycle arrest in metformin treated breast cancer cells involves activation of AMPK, downregulation of cyclin D1, and requires p27Kip1 or p21Cip1. J Mol Signal 3:18, 2008.
-
(2008)
J Mol Signal
, vol.3
, pp. 18
-
-
Zhuang, Y.1
Miskimins, W.K.2
-
33
-
-
33847080728
-
AMP-activated protein kinase in metabolic control and insulin signaling
-
Towler MC and Hardie DG: AMP-activated protein kinase in metabolic control and insulin signaling. Circ Res 100:328-341, 2007.
-
(2007)
Circ Res
, vol.100
, pp. 328-341
-
-
Towler, M.C.1
Hardie, D.G.2
-
34
-
-
50649101095
-
Puzzles, promises and a cure for ageing
-
Vijg J and Campisi J: Puzzles, promises and a cure for ageing. Nature 454:1065-1071, 2008.
-
(2008)
Nature
, vol.454
, pp. 1065-1071
-
-
Vijg, J.1
Campisi, J.2
-
35
-
-
84871458229
-
Glucose induces autophagy under starvation conditions by a p38 MAPK-dependent pathway
-
Moruno-Manchon JF, Perez-Jimenez E and Knecht E: Glucose induces autophagy under starvation conditions by a p38 MAPK-dependent pathway. Biochem J 449:497-506, 2013.
-
(2013)
Biochem J
, vol.449
, pp. 497-506
-
-
Moruno-Manchon, J.F.1
Perez-Jimenez, E.2
Knecht, E.3
-
36
-
-
84873608350
-
The LKB1-AMPK pathway-friend or foe in cancer?
-
Hardie DG: The LKB1-AMPK pathway-friend or foe in cancer? Cancer Cell 23:131-142, 2013.
-
(2013)
Cancer Cell
, vol.23
, pp. 131-142
-
-
Hardie, D.G.1
-
37
-
-
79251582476
-
Toll-like receptor 4 mediates lipopolysaccharide-induced muscle catabolism via coordinate activation of ubiquitin-proteasome and autophagy-lysosome pathways
-
Doyle A, Zhang G, Abdel Fattah EA, Eissa NT and Li YP: Toll-like receptor 4 mediates lipopolysaccharide-induced muscle catabolism via coordinate activation of ubiquitin-proteasome and autophagy-lysosome pathways. FASEB J 25:99-110, 2011.
-
(2011)
FASEB J
, vol.25
, pp. 99-110
-
-
Doyle, A.1
Zhang, G.2
Abdel Fattah, E.A.3
Eissa, N.T.4
Li, Y.P.5
-
38
-
-
84863610034
-
IFN.γ elicits macrophage autophagy via the p38 MAPK signaling pathway
-
Matsuzawa T, Kim B-H, Shenoy AR, Kamitani S, Miyake M and Macmicking JD: IFN.γ elicits macrophage autophagy via the p38 MAPK signaling pathway. J Immunol 189:813-818, 2012.
-
(2012)
J Immunol
, vol.189
, pp. 813-818
-
-
Matsuzawa, T.1
Kim, B.-H.2
Shenoy, A.R.3
Kamitani, S.4
Miyake, M.5
Macmicking, J.D.6
-
39
-
-
75649085703
-
Coordinated regulation of autophagy by p38alpha MAPK through mAtg9 and p38IP
-
Webber JL and Tooze SA: Coordinated regulation of autophagy by p38alpha MAPK through mAtg9 and p38IP. EMBO J 29:27-40, 2010.
-
(2010)
EMBO J
, vol.29
, pp. 27-40
-
-
Webber, J.L.1
Tooze, S.A.2
-
40
-
-
77953988178
-
Triterpenes from Ganoderma Lucidum induce autophagy in colon cancer through the inhibition of p38 mitogen-activated kinase (p38 MAPK)
-
Thyagarajan A, Jedinak A, Nguyen H, et al: Triterpenes from Ganoderma Lucidum induce autophagy in colon cancer through the inhibition of p38 mitogen-activated kinase (p38 MAPK). Nutr Cancer 62:630-640, 2010.
-
(2010)
Nutr Cancer
, vol.62
, pp. 630-640
-
-
Thyagarajan, A.1
Jedinak, A.2
Nguyen, H.3
-
41
-
-
0345447402
-
Hormone responsive human breast cancer in long-term tissue culture: Effect of insulin
-
Osborne CK, Bolan G, Monaco ME and Lippman ME: Hormone responsive human breast cancer in long-term tissue culture: effect of insulin. Proc Natl Acad Sci USA 73:4536-4540, 1976.
-
(1976)
Proc Natl Acad Sci USA
, vol.73
, pp. 4536-4540
-
-
Osborne, C.K.1
Bolan, G.2
Monaco, M.E.3
Lippman, M.E.4
-
42
-
-
84907691070
-
-
Distributed by: Bristol-Myers Squibb Company Princeton, NJ 08543, USA
-
Metformin insert: 1-6, 2009. Distributed by: Bristol-Myers Squibb Company Princeton, NJ 08543, USA. http://packageinserts-bms.com/pi/pi-glucophage-xr.pdf
-
(2009)
Metformin Insert
, pp. 1-6
-
-
-
43
-
-
84883165443
-
Repositioning metformin for cancer prevention and treatment
-
Quinn BJ, Kitagawa H, Memmott RM, Gills JJ and Dennis PA: Repositioning metformin for cancer prevention and treatment. Trends Endocrinol Metabol 24:469-480, 2013.
-
(2013)
Trends Endocrinol Metabol
, vol.24
, pp. 469-480
-
-
Quinn, B.J.1
Kitagawa, H.2
Memmott, R.M.3
Gills, J.J.4
Dennis, P.A.5
-
45
-
-
59449093294
-
Therapeutic metformin/AMPK activation promotes the angiogenic phenotype in the ERα negative MDA-MB-435 breast cancer model
-
Hadad SM, Appleyard V and Thompson AM: Therapeutic metformin/AMPK activation promotes the angiogenic phenotype in the ERα negative MDA-MB-435 breast cancer model. Breast Cancer Res Treat 114:391-399, 2009.
-
(2009)
Breast Cancer Res Treat
, vol.114
, pp. 391-399
-
-
Hadad, S.M.1
Appleyard, V.2
Thompson, A.M.3
-
46
-
-
84862907716
-
IGF1/insulin receptor kinase inhibition by BMS-536924 is better tolerated than alloxan-induced hypoinsulinemia and more effective than metformin in the treatment of experimental insulin-responsive breast cancer
-
Dool CJ, Mashhedi H, Zakikhani M, et al: IGF1/insulin receptor kinase inhibition by BMS-536924 is better tolerated than alloxan-induced hypoinsulinemia and more effective than metformin in the treatment of experimental insulin-responsive breast cancer. Endocr Relat Cancer 18:699-709, 2011.
-
(2011)
Endocr Relat Cancer
, vol.18
, pp. 699-709
-
-
Dool, C.J.1
Mashhedi, H.2
Zakikhani, M.3
-
47
-
-
0028158709
-
Accumulation of metformin by tissues of the normal and diabetic mouse
-
Wilcock C and Bailey CJ: Accumulation of metformin by tissues of the normal and diabetic mouse. Xenobiotica 24:49-57, 1994.
-
(1994)
Xenobiotica
, vol.24
, pp. 49-57
-
-
Wilcock, C.1
Bailey, C.J.2
-
48
-
-
20444461067
-
Metformin and reduced risk of cancer in diabetic patients
-
Evans JM, Donnelly LA, Emslie-Smith AM, Alessi DR and Morris AD: Metformin and reduced risk of cancer in diabetic patients. BMJ 330:1304-1305, 2005.
-
(2005)
BMJ
, vol.330
, pp. 1304-1305
-
-
Evans, J.M.1
Donnelly, L.A.2
Emslie-Smith, A.M.3
Alessi, D.R.4
Morris, A.D.5
-
50
-
-
84858695046
-
Cancer risk in diabetic patients treated with metformin: A systematic review and meta-analysis
-
Noto H, Goto A, Tsujimoto T and Noda M: Cancer risk in diabetic patients treated with metformin: a systematic review and meta-analysis. PLoS One 7: e33411, 2012.
-
(2012)
PLoS One
, vol.7
, pp. e33411
-
-
Noto, H.1
Goto, A.2
Tsujimoto, T.3
Noda, M.4
-
52
-
-
84877576018
-
Metformin and the risk of endometrial cancer: A case-control analysis
-
Becker C, Jick SS, Meier CR and Bodmer M: Metformin and the risk of endometrial cancer: a case-control analysis. Gynecol Oncol 129:565-569, 2013.
-
(2013)
Gynecol Oncol
, vol.129
, pp. 565-569
-
-
Becker, C.1
Jick, S.S.2
Meier, C.R.3
Bodmer, M.4
-
53
-
-
84867404716
-
Metformin does not alter the risk of lung cancer: A case-control analysis
-
Bodmer M, Becker C, Jick SS and Meier CR: Metformin does not alter the risk of lung cancer: a case-control analysis. Lung Cancer 78:133-137, 2012.
-
(2012)
Lung Cancer
, vol.78
, pp. 133-137
-
-
Bodmer, M.1
Becker, C.2
Jick, S.S.3
Meier, C.R.4
-
54
-
-
84857073798
-
Use of metformin is not associated with a decreased risk of colorectal cancer: A case-control analysis
-
Bodmer M, Becker C, Meier C, Jick SS and Meier CR: Use of metformin is not associated with a decreased risk of colorectal cancer: a case-control analysis. Cancer Epidemiol Biomarkers Prev 21:280-286, 2012.
-
(2012)
Cancer Epidemiol Biomarkers Prev
, vol.21
, pp. 280-286
-
-
Bodmer, M.1
Becker, C.2
Meier, C.3
Jick, S.S.4
Meier, C.R.5
-
55
-
-
84890791760
-
Effect of metformin on prostate cancer outcomes after radical prostatectomy
-
Kaushik D, Karnes RJ, Eisenberg MS, Rangel LJ, Carlson RE and Bergstralh EJ: Effect of metformin on prostate cancer outcomes after radical prostatectomy. Urol Oncol 32:43-e1-7, 2013.
-
(2013)
Urol Oncol
, vol.32
, pp. 43e1-47e1
-
-
Kaushik, D.1
Karnes, R.J.2
Eisenberg, M.S.3
Rangel, L.J.4
Carlson, R.E.5
Bergstralh, E.J.6
-
56
-
-
84859605287
-
Use of antidiabetic agents and the risk of pancreatic cancer: A case-control analysis
-
Bodmer M, Becker C, Meier C, Jick SS and Meier CR: Use of antidiabetic agents and the risk of pancreatic cancer: a case-control analysis. Am J Gastroenterol 107:620-626, 2012.
-
(2012)
Am J Gastroenterol
, vol.107
, pp. 620-626
-
-
Bodmer, M.1
Becker, C.2
Meier, C.3
Jick, S.S.4
Meier, C.R.5
-
57
-
-
84866156935
-
The effect of metformin and thiazolidinedione use on lung cancer in diabetics
-
Mazzone PJ, Rai H, Beukemann M, Xu M, Jain A and Sasidhar M: The effect of metformin and thiazolidinedione use on lung cancer in diabetics. BMC Cancer 12:410, 2012.
-
(2012)
BMC Cancer
, vol.12
, pp. 410
-
-
Mazzone, P.J.1
Rai, H.2
Beukemann, M.3
Xu, M.4
Jain, A.5
Sasidhar, M.6
-
58
-
-
80054767295
-
Use of metformin and the risk of ovarian cancer: A case-control analysis
-
Bodmer M, Becker C, Meier C, Jick SS and Meier CR: Use of metformin and the risk of ovarian cancer: a case-control analysis. Gynecol Oncol 123:200-204, 2011.
-
(2011)
Gynecol Oncol
, vol.123
, pp. 200-204
-
-
Bodmer, M.1
Becker, C.2
Meier, C.3
Jick, S.S.4
Meier, C.R.5
-
59
-
-
77953539812
-
Long-term metformin use is associated with decreased risk of breast cancer
-
Bodmer M, Meier C, Krahenbuhl S, Jick SS and Meier CR: Long-term metformin use is associated with decreased risk of breast cancer. Diabetes Care 33:1304-1308, 2010.
-
(2010)
Diabetes Care
, vol.33
, pp. 1304-1308
-
-
Bodmer, M.1
Meier, C.2
Krahenbuhl, S.3
Jick, S.S.4
Meier, C.R.5
-
60
-
-
55449124298
-
Metformin suppresses intestinal polyp growth in ApcMin/+ mice
-
Tomimoto A, Endo H, Sugiyama M, et al: Metformin suppresses intestinal polyp growth in ApcMin/+ mice. Cancer Science 99:2136-2141, 2008.
-
(2008)
Cancer Science
, vol.99
, pp. 2136-2141
-
-
Tomimoto, A.1
Endo, H.2
Sugiyama, M.3
-
61
-
-
77955818623
-
Retinoblastoma cells are inhibited by aminoimidazole carboxamide ribonucleotide (AICAR) partially through activation of AMP-dependent kinase
-
Theodoropoulou S, Kolovou PE, Morizane Y, et al: Retinoblastoma cells are inhibited by aminoimidazole carboxamide ribonucleotide (AICAR) partially through activation of AMP-dependent kinase. FASEB J 24:2620-2630, 2010.
-
(2010)
FASEB J
, vol.24
, pp. 2620-2630
-
-
Theodoropoulou, S.1
Kolovou, P.E.2
Morizane, Y.3
-
62
-
-
28244466264
-
5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase
-
Rattan R, Giri S, Singh AK and Singh I: 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase. J Biol Chem 280:39582-39593, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 39582-39593
-
-
Rattan, R.1
Giri, S.2
Singh, A.K.3
Singh, I.4
-
63
-
-
0345167800
-
TSC2 mediates cellular energy response to control cell growth and survival
-
Inoki KK, Zhu TT and Guan K-LK: TSC2 mediates cellular energy response to control cell growth and survival. Cell 115:577-590, 2003.
-
(2003)
Cell
, vol.115
, pp. 577-590
-
-
Inoki, K.K.1
Zhu, T.T.2
Guan, K.-L.K.3
-
64
-
-
1942469564
-
Thr2446 is a novel mammalian target of rapamycin (mTOR) phosphorylation site regulated by nutrient status
-
Cheng S W Y, Fryer L G D, Carling D and Shepherd PR: Thr2446 is a novel mammalian target of rapamycin (mTOR) phosphorylation site regulated by nutrient status. J Biol Chem 279:15719-15722, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 15719-15722
-
-
Cheng, S.W.Y.1
Fryer, L.G.D.2
Carling, D.3
Shepherd, P.R.4
-
66
-
-
25444440875
-
The role of autophagy in cancer development and response to therapy
-
Kondo Y, Kanzawa T, Sawaya R and Kondo S: The role of autophagy in cancer development and response to therapy. Nat Rev Cancer 5:726-734, 2005.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 726-734
-
-
Kondo, Y.1
Kanzawa, T.2
Sawaya, R.3
Kondo, S.4
-
67
-
-
0036324142
-
The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism
-
Hawley SA, Gadalla AE, Olsen GS and Hardie DG: The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism. Diabetes 51:2420-2425, 2002.
-
(2002)
Diabetes
, vol.51
, pp. 2420-2425
-
-
Hawley, S.A.1
Gadalla, A.E.2
Olsen, G.S.3
Hardie, D.G.4
-
68
-
-
77955287742
-
Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner
-
Kalender A, Selvaraj A, Kim SY, et al: Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner. Cell Metab 11:390-401, 2010.
-
(2010)
Cell Metab
, vol.11
, pp. 390-401
-
-
Kalender, A.1
Selvaraj, A.2
Kim, S.Y.3
-
69
-
-
67650514082
-
Metformin induces unique biological and molecular responses in triple negative breast cancer cells
-
Liu B, Fan Z, Edgerton SM, et al: Metformin induces unique biological and molecular responses in triple negative breast cancer cells. Cell Cycle 8:2031-2040, 2009.
-
(2009)
Cell Cycle
, vol.8
, pp. 2031-2040
-
-
Liu, B.1
Fan, Z.2
Edgerton, S.M.3
-
70
-
-
84863229883
-
LY294002 and metformin cooperatively enhance the inhibition of growth and the induction of apoptosis of ovarian cancer cells
-
Li C, Liu V W S, Chan DW, Yao KM and Ngan H Y S: LY294002 and metformin cooperatively enhance the inhibition of growth and the induction of apoptosis of ovarian cancer cells. Int J Gynecol Cancer 22:15-22, 2012.
-
(2012)
Int J Gynecol Cancer
, vol.22
, pp. 15-22
-
-
Li, C.1
Liu, V.W.S.2
Chan, D.W.3
Yao, K.M.4
Ngan, H.Y.S.5
-
71
-
-
33645556312
-
Bax translocates to mitochondria of heart cells during simulated ischaemia: Involvement of AMP-activated and p38 mitogen-activated protein kinases
-
Capano M and Crompton M: Bax translocates to mitochondria of heart cells during simulated ischaemia: involvement of AMP-activated and p38 mitogen-activated protein kinases. Biochem J 395:57-64, 2006.
-
(2006)
Biochem J
, vol.395
, pp. 57-64
-
-
Capano, M.1
Crompton, M.2
-
72
-
-
0035798668
-
Stimulation of glucose transport by AMP-activated protein kinase via activation of p38 mitogen-activated protein kinase
-
Xi X, Han J and Zhang JZ: Stimulation of glucose transport by AMP-activated protein kinase via activation of p38 mitogen-activated protein kinase. J Biol Chem 276:41029-41034, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 41029-41034
-
-
Xi, X.1
Han, J.2
Zhang, J.Z.3
-
73
-
-
84872294586
-
Metformin selectively affects human glioblastoma tumor-initiating cell viability: A role for metformin-induced inhibition of Akt
-
Wurth R, Pattarozzi A, Gatti M, et al: Metformin selectively affects human glioblastoma tumor-initiating cell viability: A role for metformin-induced inhibition of Akt. Cell Cycle 12:145-156, 2013.
-
(2013)
Cell Cycle
, vol.12
, pp. 145-156
-
-
Wurth, R.1
Pattarozzi, A.2
Gatti, M.3
-
74
-
-
84859463669
-
Metformin inhibits cell proliferation, migration and invasion by attenuating CSC function mediated by deregulating miRNAs in pancreatic cancer cells
-
Bao B, Wang Z, Ali S, et al: Metformin inhibits cell proliferation, migration and invasion by attenuating CSC function mediated by deregulating miRNAs in pancreatic cancer cells. Cancer Prevent Res 5:355-364, 2012.
-
(2012)
Cancer Prevent Res
, vol.5
, pp. 355-364
-
-
Bao, B.1
Wang, Z.2
Ali, S.3
-
75
-
-
79959764729
-
Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1
-
Ben Sahra I, Regazzetti C, Robert G, et al: Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1. Cancer Res 71:4366-4372, 2011.
-
(2011)
Cancer Res
, vol.71
, pp. 4366-4372
-
-
Sahra, I.B.1
Regazzetti, C.2
Robert, G.3
-
76
-
-
84862848716
-
Cancer risk associated with use of metformin and sulfonylurea in type 2 diabetes: A meta-analysis
-
Soranna D, Scotti L, Zambon A, et al: Cancer risk associated with use of metformin and sulfonylurea in type 2 diabetes: a meta-analysis. Oncologist 17:813-822, 2012.
-
(2012)
Oncologist
, vol.17
, pp. 813-822
-
-
Soranna, D.1
Scotti, L.2
Zambon, A.3
-
78
-
-
79955490053
-
Metformin decreases the dose of chemotherapy for prolonging tumor remission in mouse xenografts involving multiple cancer cell types
-
Iliopoulos D, Hirsch HA and Struhl K: Metformin decreases the dose of chemotherapy for prolonging tumor remission in mouse xenografts involving multiple cancer cell types. Cancer Res 71:3196-3201, 2011.
-
(2011)
Cancer Res
, vol.71
, pp. 3196-3201
-
-
Iliopoulos, D.1
Hirsch, H.A.2
Struhl, K.3
-
79
-
-
70350236538
-
Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission
-
Hirsch HA, Iliopoulos D, Tsichlis PN and Struhl K: Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission. Cancer Res 69:7507-7511, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 7507-7511
-
-
Hirsch, H.A.1
Iliopoulos, D.2
Tsichlis, P.N.3
Struhl, K.4
-
80
-
-
77953527360
-
Metformin and cancer: Doses, mechanisms and the dandelion and hormetic phenomena
-
Martin-Castillo B, Vazquez-Martin A, Oliveras-Ferraros C and Menendez JA: Metformin and cancer: doses, mechanisms and the dandelion and hormetic phenomena. Cell Cycle 9:1057-1064, 2010.
-
(2010)
Cell Cycle
, vol.9
, pp. 1057-1064
-
-
Martin-Castillo, B.1
Vazquez-Martin, A.2
Oliveras-Ferraros, C.3
Menendez, J.A.4
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