Minocycline inhibits ICAD degradation and the NF-κB activation induced by 6-OHDA in PC12 cells

Brain Research

Volumn 1586, Issue , 2014, Pages 1-11

  Jiang, Bao Ping ^a,b   Le, Liang ^a   Xu, Li Jia ^a,b   Xiao, Pei Gen ^a,b  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

Author keywords

6 Hydroxydopamine; Minocycline; Nuclear factor B; Parkinson's disease

Indexed keywords

CASPASE 3; CATALASE; ICAD PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LACTATE DEHYDROGENASE; MALONALDEHYDE; MINOCYCLINE; OXIDOPAMINE; PROTEIN; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; (Z)2-(5-(4-METHOXYBENZYLIDENE)-2,4-DIOXOTHIAZOLIDIN-3-YL)ACETIC ACID; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ADRENERGIC RECEPTOR STIMULATING AGENT; APOPTOSIS REGULATORY PROTEIN; CASPASE-ACTIVATED DNASE INHIBITOR; NEUROPROTECTIVE AGENT;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME RELEASE; IN VITRO STUDY; NEUROPROTECTION; NICK END LABELING; PARKINSON DISEASE; PC12 CELL LINE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; ANIMAL; DOSE RESPONSE; DRUG EFFECTS; DRUG INTERACTION; GENE EXPRESSION REGULATION; METABOLISM; RAT; TUNEL ASSAY;

ADRENERGIC AGENTS; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASE 3; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; GENE EXPRESSION REGULATION; IN SITU NICK-END LABELING; L-LACTATE DEHYDROGENASE; MINOCYCLINE; NEUROPROTECTIVE AGENTS; NF-KAPPA B; OXIDOPAMINE; PC12 CELLS; RATS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; THIAZOLIDINEDIONES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84907677900     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2014.08.001     Document Type: Article

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