-
1
-
-
33846246406
-
Syndecans in wound healing, inflammation and vascular biology
-
Alexopoulou, A. N., Multhaupt, H. A., and Couchman, J. R. (2007). Syndecans in wound healing, inflammation and vascular biology. Int. J. Biochem. Cell Biol. 39, 505-528.
-
(2007)
Int. J. Biochem. Cell Biol
, vol.39
, pp. 505-528
-
-
Alexopoulou, A.N.1
Multhaupt, H.A.2
Couchman, J.R.3
-
2
-
-
34248159909
-
Syndecan-4-dependent Rac1 regulation determines directional migration in response to the extracellular matrix
-
Bass, M. D., Roach, K. A., Morgan, M. R., Mostafavi-Pour, Z., Schoen, T., Muramatsu, T., Mayer, U., Ballestrem, C., Spatz, J. P., and Humphries, M. J. (2007). Syndecan-4-dependent Rac1 regulation determines directional migration in response to the extracellular matrix. J. Cell Biol. 177, 527-538.
-
(2007)
J. Cell Biol
, vol.177
, pp. 527-538
-
-
Bass, M.D.1
Roach, K.A.2
Morgan, M.R.3
Mostafavi-Pour, Z.4
Schoen, T.5
Muramatsu, T.6
Mayer, U.7
Ballestrem, C.8
Spatz, J.P.9
Humphries, M.J.10
-
3
-
-
5444242206
-
The syndecan-1 ectodomain regulates alphavbeta3 integrin activity in human mammary carcinoma cells
-
Beauvais, D. M., Burbach, B. J., and Rapraeger, A. C. (2004). The syndecan-1 ectodomain regulates alphavbeta3 integrin activity in human mammary carcinoma cells. J. Cell Biol. 167, 171-181.
-
(2004)
J. Cell Biol
, vol.167
, pp. 171-181
-
-
Beauvais, D.M.1
Burbach, B.J.2
Rapraeger, A.C.3
-
5
-
-
0028104088
-
Aggregation-induced association of syndecan-1 with microfilaments mediated by the cytoplasmic domain
-
Carey, D. J., Stahl, R. C., Tucker, B., Bendt, K. A., and Cizmeci-Smith, G. (1994). Aggregation-induced association of syndecan-1 with microfilaments mediated by the cytoplasmic domain. Exp. Cell Res. 214, 12-21.
-
(1994)
Exp. Cell Res
, vol.214
, pp. 12-21
-
-
Carey, D.J.1
Stahl, R.C.2
Tucker, B.3
Bendt, K.A.4
Cizmeci-Smith, G.5
-
6
-
-
0345169052
-
Syndecans: Proteoglycan regulators of cell-surface microdomains?
-
Couchman, J. R. (2003). Syndecans: proteoglycan regulators of cell-surface microdomains? Nat. Rev. Mol. Cell Biol. 4, 926-937.
-
(2003)
Nat. Rev. Mol. Cell Biol
, vol.4
, pp. 926-937
-
-
Couchman, J.R.1
-
7
-
-
0032746544
-
Syndecan-4 and integrins: Combinatorial signaling in cell adhesion
-
Couchman, J. R., and Woods, A. (1999). Syndecan-4 and integrins: combinatorial signaling in cell adhesion. J. Cell Sci. 112(Pt 20), 3415-3420.
-
(1999)
J. Cell Sci
, vol.112
, Issue.PART 20
, pp. 3415-3420
-
-
Couchman, J.R.1
Woods, A.2
-
8
-
-
0037214892
-
Keratinocyte motility induced by TGF-beta1 is accompanied by dramatic changes in cellular interactions with laminin 5
-
Decline, F., Okamoto, O., Mallein-Gerin, F., Helbert, B., Bernaud, J., Rigal, D., and Rousselle, P. (2003). Keratinocyte motility induced by TGF-beta1 is accompanied by dramatic changes in cellular interactions with laminin 5. Cell Motil. Cytoskelet. 54, 64-80.
-
(2003)
Cell Motil. Cytoskelet
, vol.54
, pp. 64-80
-
-
Decline, F.1
Okamoto, O.2
Mallein-Gerin, F.3
Helbert, B.4
Bernaud, J.5
Rigal, D.6
Rousselle, P.7
-
9
-
-
0035145150
-
Delayed wound repair and impaired angiogenesis in mice lacking syndecan-4
-
Echtermeyer, F., Streit, M., Wilcox-Adelman, S., Saoncella, S., Denhez, F., Detmar, M., and Goetinck, P. (2001). Delayed wound repair and impaired angiogenesis in mice lacking syndecan-4. J. Clin. Invest. 107, R9-R14.
-
(2001)
J. Clin. Invest
, vol.107
-
-
Echtermeyer, F.1
Streit, M.2
Wilcox-Adelman, S.3
Saoncella, S.4
Denhez, F.5
Detmar, M.6
Goetinck, P.7
-
10
-
-
0025739490
-
Induced expression of syndecan in healing wounds
-
Elenius, K., Vainio, S., Laato, M., Salmivirta, M., Thesleff, I., and Jalkanen, M. (1991). Induced expression of syndecan in healing wounds. J. Cell Biol. 114, 585-595.
-
(1991)
J. Cell Biol
, vol.114
, pp. 585-595
-
-
Elenius, K.1
Vainio, S.2
Laato, M.3
Salmivirta, M.4
Thesleff, I.5
Jalkanen, M.6
-
11
-
-
33749441307
-
The role of syndecans in disease and wound healing
-
Fears, C. Y., and Woods, A. (2006). The role of syndecans in disease and wound healing. Matrix Biol. 25, 443-456.
-
(2006)
Matrix Biol
, vol.25
, pp. 443-456
-
-
Fears, C.Y.1
Woods, A.2
-
12
-
-
0029850943
-
Syndecans-1 and -4 are induced during wound repair of neonatal but not fetal skin
-
Gallo, R., Kim, C., Kokenyesi, R., Adzick, N. S., and Bernfield, M. (1996). Syndecans-1 and -4 are induced during wound repair of neonatal but not fetal skin. J. Invest. Dermatol. 107, 676-683.
-
(1996)
J. Invest. Dermatol
, vol.107
, pp. 676-683
-
-
Gallo, R.1
Kim, C.2
Kokenyesi, R.3
Adzick, N.S.4
Bernfield, M.5
-
13
-
-
0032489876
-
Processing of laminin-5 and its functional consequences: Role of plasmin and tissue-type plasminogen activator
-
Goldfinger, L. E., Stack, M. S., and Jones, J. C. (1998). Processing of laminin-5 and its functional consequences: role of plasmin and tissue-type plasminogen activator. J. Cell Biol. 141, 255-265.
-
(1998)
J. Cell Biol
, vol.141
, pp. 255-265
-
-
Goldfinger, L.E.1
Stack, M.S.2
Jones, J.C.3
-
14
-
-
24344452170
-
Wounding activates p38 map kinase and activation transcription factor 3 in leading keratinocytes
-
Harper, E. G., Alvares, S. M., and Carter, W. G. (2005). Wounding activates p38 map kinase and activation transcription factor 3 in leading keratinocytes. J. Cell Sci. 118, 3471-3485.
-
(2005)
J. Cell Sci
, vol.118
, pp. 3471-3485
-
-
Harper, E.G.1
Alvares, S.M.2
Carter, W.G.3
-
15
-
-
0031882281
-
Laminin-5 expression is independent of the injury and the microenvironment during reepithelialization of wounds
-
Kainulainen, T., Hakkinen, L., Hamidi, S., Larjava, K., Kallioinen, M., Peltonen, J., Salo, T., Larjava, H., and Oikarinen, A. (1998). Laminin-5 expression is independent of the injury and the microenvironment during reepithelialization of wounds. J. Histochem. Cytochem. 46, 353-360.
-
(1998)
J. Histochem. Cytochem
, vol.46
, pp. 353-360
-
-
Kainulainen, T.1
Hakkinen, L.2
Hamidi, S.3
Larjava, K.4
Kallioinen, M.5
Peltonen, J.6
Salo, T.7
Larjava, H.8
Oikarinen, A.9
-
16
-
-
0037015150
-
Identification of neurite outgrowth promoting sites on the laminin alpha 3 chain G domain
-
Kato, K., Utani, A., Suzuki, N., Mochizuki, M., Yamada, M., Nishi, N., Matsuura, H., Shinkai, H., and Nomizu, M. (2002). Identification of neurite outgrowth promoting sites on the laminin alpha 3 chain G domain. Biochemistry 41, 10747-10753.
-
(2002)
Biochemistry
, vol.41
, pp. 10747-10753
-
-
Kato, K.1
Utani, A.2
Suzuki, N.3
Mochizuki, M.4
Yamada, M.5
Nishi, N.6
Matsuura, H.7
Shinkai, H.8
Nomizu, M.9
-
17
-
-
33748306120
-
Integrin structures and conformational signaling
-
Luo, B. H., and Springer, T. A. (2006). Integrin structures and conformational signaling. Curr. Opin. Cell Biol. 18, 579-586.
-
(2006)
Curr. Opin. Cell Biol
, vol.18
, pp. 579-586
-
-
Luo, B.H.1
Springer, T.A.2
-
18
-
-
33746067151
-
Syndecan-1 regulates alphavbeta5 integrin activity in B82L fibroblasts
-
McQuade, K. J., Beauvais, D. M., Burbach, B. J., and Rapraeger, A. C. (2006). Syndecan-1 regulates alphavbeta5 integrin activity in B82L fibroblasts. J. Cell Sci. 119, 2445-2456.
-
(2006)
J. Cell Sci
, vol.119
, pp. 2445-2456
-
-
McQuade, K.J.1
Beauvais, D.M.2
Burbach, B.J.3
Rapraeger, A.C.4
-
19
-
-
20344381818
-
Laminin alpha3 LG4 module induces keratinocyte migration: Involvement of matrix metalloproteinase-9
-
Momota, Y., Suzuki, N., Kasuya, Y., Kobayashi, T., Mizoguchi, M., Yokoyama, F., Nomizu, M., Shinkai, H., Iwasaki, T., and Utani, A. (2005). Laminin alpha3 LG4 module induces keratinocyte migration: involvement of matrix metalloproteinase-9. J. Recept. Signal Transduct. Res. 25, 1-17.
-
(2005)
J. Recept. Signal Transduct. Res
, vol.25
, pp. 1-17
-
-
Momota, Y.1
Suzuki, N.2
Kasuya, Y.3
Kobayashi, T.4
Mizoguchi, M.5
Yokoyama, F.6
Nomizu, M.7
Shinkai, H.8
Iwasaki, T.9
Utani, A.10
-
20
-
-
36448970493
-
Synergistic control of cell adhesion by integrins and syndecans
-
Morgan, M. R., Humphries, M. J., and Bass, M. D. (2007). Synergistic control of cell adhesion by integrins and syndecans. Nat. Rev. Mol. Cell Biol. 8, 957-969.
-
(2007)
Nat. Rev. Mol. Cell Biol
, vol.8
, pp. 957-969
-
-
Morgan, M.R.1
Humphries, M.J.2
Bass, M.D.3
-
21
-
-
0037437153
-
Integrin-specific signaling pathways controlling focal adhesion formation and cell migration
-
Mostafavi-Pour, Z., Askari, J. A., Parkinson, S. J., Parker, P. J., Ng, T. T., and Humphries, M. J. (2003). Integrin-specific signaling pathways controlling focal adhesion formation and cell migration. J. Cell Biol. 161, 155-167.
-
(2003)
J. Cell Biol
, vol.161
, pp. 155-167
-
-
Mostafavi-Pour, Z.1
Askari, J.A.2
Parkinson, S.J.3
Parker, P.J.4
Ng, T.T.5
Humphries, M.J.6
-
22
-
-
0029664954
-
The inhibitory anti-beta1 integrin monoclonal antibody 13 recognizes an epitope that is attenuated by ligand occupancy. Evidence for allosteric inhibition of integrin function
-
Mould, A. P., Akiyama, S. K., and Humphries, M. J. (1996). The inhibitory anti-beta1 integrin monoclonal antibody 13 recognizes an epitope that is attenuated by ligand occupancy. Evidence for allosteric inhibition of integrin function. J. Biol. Chem. 271, 20365-20374.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 20365-20374
-
-
Mould, A.P.1
Akiyama, S.K.2
Humphries, M.J.3
-
23
-
-
0037205483
-
Integrin activation involves a conformational change in the alpha 1 helix of the beta subunit A-domain
-
Mould, A. P., Askari, J. A., Barton, S., Kline, A. D., McEwan, P. A., Craig, S. E., and Humphries, M. J. (2002). Integrin activation involves a conformational change in the alpha 1 helix of the beta subunit A-domain. J. Biol. Chem. 277, 19800-19805.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 19800-19805
-
-
Mould, A.P.1
Askari, J.A.2
Barton, S.3
Kline, A.D.4
McEwan, P.A.5
Craig, S.E.6
Humphries, M.J.7
-
24
-
-
0032079781
-
Regulation of integrin function: Evidence that bivalent-cation-induced conformational changes lead to the unmasking of ligand-binding sites within integrin alpha5 beta1
-
Mould, A. P., Garratt, A. N., Puzon-McLaughlin, W., Takada, Y., and Humphries, M. J. (1998). Regulation of integrin function: evidence that bivalent-cation-induced conformational changes lead to the unmasking of ligand-binding sites within integrin alpha5 beta1. Biochem. J. 331(Pt 3), 821-828.
-
(1998)
Biochem. J
, vol.331
, Issue.PART 3
, pp. 821-828
-
-
Mould, A.P.1
Garratt, A.N.2
Puzon-McLaughlin, W.3
Takada, Y.4
Humphries, M.J.5
-
25
-
-
4444281827
-
Regulation of integrin function through conformational complexity: Not simply a knee-jerk reaction?
-
Mould, A. P., and Humphries, M. J. (2004). Regulation of integrin function through conformational complexity: not simply a knee-jerk reaction? Curr. Opin. Cell Biol. 16, 544-551.
-
(2004)
Curr. Opin. Cell Biol
, vol.16
, pp. 544-551
-
-
Mould, A.P.1
Humphries, M.J.2
-
26
-
-
0033813105
-
Deposition of laminin 5 in epidermal wounds regulates integrin signaling and adhesion
-
Nguyen, B. P., Ryan, M. C., Gil, S. G., and Carter, W. G. (2000). Deposition of laminin 5 in epidermal wounds regulates integrin signaling and adhesion. Curr. Opin. Cell Biol. 12, 554-562.
-
(2000)
Curr. Opin. Cell Biol
, vol.12
, pp. 554-562
-
-
Nguyen, B.P.1
Ryan, M.C.2
Gil, S.G.3
Carter, W.G.4
-
27
-
-
0032478739
-
Integrin activation by dithiothreitol or Mn2+ induces a ligand-occupied conformation and exposure of a novel NH2-terminal regulatory site on the beta1 integrin chain
-
Ni, H., Li, A., Simonsen, N., and Wilkins, J. A. (1998). Integrin activation by dithiothreitol or Mn2+ induces a ligand-occupied conformation and exposure of a novel NH2-terminal regulatory site on the beta1 integrin chain. J. Biol. Chem. 273, 7981-7987.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 7981-7987
-
-
Ni, H.1
Li, A.2
Simonsen, N.3
Wilkins, J.A.4
-
28
-
-
0032455415
-
Localisation of a novel adhesion blocking epitope on the human beta 1 integrin chain
-
Ni, H., and Wilkins, J. A. (1998). Localisation of a novel adhesion blocking epitope on the human beta 1 integrin chain. Cell Adhes. Commun. 5, 257-271.
-
(1998)
Cell Adhes. Commun
, vol.5
, pp. 257-271
-
-
Ni, H.1
Wilkins, J.A.2
-
29
-
-
0242414749
-
Normal human keratinocytes bind to the alpha3LG4/5 domain of unprocessed laminin-5 through the receptor syndecan-1
-
Okamoto, O., Bachy, S., Odenthal, U., Bernaud, J., Rigal, D., Lortat-Jacob, H., Smyth, N., and Rousselle, P. (2003). Normal human keratinocytes bind to the alpha3LG4/5 domain of unprocessed laminin-5 through the receptor syndecan-1. J. Biol. Chem. 278, 44168-44177.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 44168-44177
-
-
Okamoto, O.1
Bachy, S.2
Odenthal, U.3
Bernaud, J.4
Rigal, D.5
Lortat-Jacob, H.6
Smyth, N.7
Rousselle, P.8
-
30
-
-
0028899738
-
Expression of proteoglycans and hyaluronan during wound healing
-
Oksala, O., Salo, T., Tammi, R., Hakkinen, L., Jalkanen, M., Inki, P., and Larjava, H. (1995). Expression of proteoglycans and hyaluronan during wound healing. J. Histochem. Cytochem. 43, 125-135.
-
(1995)
J. Histochem. Cytochem
, vol.43
, pp. 125-135
-
-
Oksala, O.1
Salo, T.2
Tammi, R.3
Hakkinen, L.4
Jalkanen, M.5
Inki, P.6
Larjava, H.7
-
31
-
-
27544449024
-
Focal adhesion kinase regulates syndecan-2-mediated tumorigenic activity of HT1080 fibrosarcoma cells
-
Park, H., Han, I., Kwon, H. J., and Oh, E. S. (2005). Focal adhesion kinase regulates syndecan-2-mediated tumorigenic activity of HT1080 fibrosarcoma cells. Cancer Res. 65, 9899-9905.
-
(2005)
Cancer Res
, vol.65
, pp. 9899-9905
-
-
Park, H.1
Han, I.2
Kwon, H.J.3
Oh, E.S.4
-
32
-
-
0028085840
-
Cloning of the LamA3 gene encoding the alpha 3 chain of the adhesive ligand epiligrin. Expression in wound repair
-
Ryan, M. C., Tizard, R., VanDevanter, D. R., and Carter, W. G. (1994). Cloning of the LamA3 gene encoding the alpha 3 chain of the adhesive ligand epiligrin. Expression in wound repair. J. Biol. Chem. 269, 22779-22787.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 22779-22787
-
-
Ryan, M.C.1
Tizard, R.2
VanDevanter, D.R.3
Carter, W.G.4
-
33
-
-
36849069343
-
A peptide derived from tenascin-C induces beta1 integrin activation through syndecan-4
-
Saito, Y. et al. (2007). A peptide derived from tenascin-C induces beta1 integrin activation through syndecan-4. J. Biol. Chem. 282, 34929-34937.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 34929-34937
-
-
Saito, Y.1
-
34
-
-
5444255540
-
Globular domains 4/5 of the laminin alpha3 chain mediate deposition of precursor laminin 5
-
Sigle, R. O. et al. (2004). Globular domains 4/5 of the laminin alpha3 chain mediate deposition of precursor laminin 5. J. Cell Sci. 117, 4481-4494.
-
(2004)
J. Cell Sci
, vol.117
, pp. 4481-4494
-
-
Sigle, R.O.1
-
35
-
-
12244305625
-
Defects in keratinocyte activation during wound healing in the syndecan-1-deficient mouse
-
Stepp, M. A. et al. (2002). Defects in keratinocyte activation during wound healing in the syndecan-1-deficient mouse. J. Cell Sci. 115, 4517-4531.
-
(2002)
J. Cell Sci
, vol.115
, pp. 4517-4531
-
-
Stepp, M.A.1
-
36
-
-
0037899925
-
ADAM12/syndecan-4 signaling promotes beta 1 integrin-dependent cell spreading through protein kinase Calpha and RhoA
-
Thodeti, C. K., Albrechtsen, R., Grauslund, M., Asmar, M., Larsson, C., Takada, Y., Mercurio, A. M., Couchman, J. R., and Wewer, U. M. (2003). ADAM12/syndecan-4 signaling promotes beta 1 integrin-dependent cell spreading through protein kinase Calpha and RhoA. J. Biol. Chem. 278, 9576-9584.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 9576-9584
-
-
Thodeti, C.K.1
Albrechtsen, R.2
Grauslund, M.3
Asmar, M.4
Larsson, C.5
Takada, Y.6
Mercurio, A.M.7
Couchman, J.R.8
Wewer, U.M.9
-
37
-
-
42349086700
-
Targeting a tumor-specific laminin domain critical for human carcinogenesis
-
Tran, M., Rousselle, P., Nokelainen, P., Tallapragada, S., Nguyen, N. T., Fincher, E. F., and Marinkovich, M. P. (2008). Targeting a tumor-specific laminin domain critical for human carcinogenesis. Cancer Res. 68, 2885-2894.
-
(2008)
Cancer Res
, vol.68
, pp. 2885-2894
-
-
Tran, M.1
Rousselle, P.2
Nokelainen, P.3
Tallapragada, S.4
Nguyen, N.T.5
Fincher, E.F.6
Marinkovich, M.P.7
-
38
-
-
0034735987
-
Isolation and activity of proteolytic fragment of laminin-5 alpha3 chain
-
Tsubota, Y., Mizushima, H., Hirosaki, T., Higashi, S., Yasumitsu, H., and Miyazaki, K. (2000). Isolation and activity of proteolytic fragment of laminin-5 alpha3 chain. Biochem. Biophys. Res. Commun. 278, 614-620.
-
(2000)
Biochem. Biophys. Res. Commun
, vol.278
, pp. 614-620
-
-
Tsubota, Y.1
Mizushima, H.2
Hirosaki, T.3
Higashi, S.4
Yasumitsu, H.5
Miyazaki, K.6
-
39
-
-
0030782678
-
Classification of 'activation' antibodies against integrin beta1 chain
-
Tsuchida, J., Ueki, S., Saito, Y., and Takagi, J. (1997). Classification of 'activation' antibodies against integrin beta1 chain. FEBS Lett. 416, 212-216.
-
(1997)
FEBS Lett
, vol.416
, pp. 212-216
-
-
Tsuchida, J.1
Ueki, S.2
Saito, Y.3
Takagi, J.4
-
40
-
-
0141594869
-
Laminin alpha 3 LG4 module induces matrix metalloproteinase-1 through mitogen-activated protein kinase signaling
-
Utani, A., Momota, Y., Endo, H., Kasuya, Y., Beck, K., Suzuki, N., Nomizu, M., and Shinkai, H. (2003). Laminin alpha 3 LG4 module induces matrix metalloproteinase-1 through mitogen-activated protein kinase signaling. J. Biol. Chem. 278, 34483-34490.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 34483-34490
-
-
Utani, A.1
Momota, Y.2
Endo, H.3
Kasuya, Y.4
Beck, K.5
Suzuki, N.6
Nomizu, M.7
Shinkai, H.8
-
41
-
-
0035800814
-
A unique sequence of the laminin alpha 3 G domain binds to heparin and promotes cell adhesion through syndecan-2 and -4
-
Utani, A., Nomizu, M., Matsuura, H., Kato, K., Kobayashi, T., Takeda, U., Aota, S., Nielsen, P. K., and Shinkai, H. (2001). A unique sequence of the laminin alpha 3 G domain binds to heparin and promotes cell adhesion through syndecan-2 and -4. J. Biol. Chem. 276, 28779-28788.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 28779-28788
-
-
Utani, A.1
Nomizu, M.2
Matsuura, H.3
Kato, K.4
Kobayashi, T.5
Takeda, U.6
Aota, S.7
Nielsen, P.K.8
Shinkai, H.9
-
42
-
-
0027278234
-
Epiligrin, a component of epithelial basement membranes, is an adhesive ligand for alpha 3 beta 1 positive T lymphocytes
-
Wayner, E. A., Gil, S. G., Murphy, G. F., Wilke, M. S., and Carter, W. G. (1993). Epiligrin, a component of epithelial basement membranes, is an adhesive ligand for alpha 3 beta 1 positive T lymphocytes. J. Cell Biol. 121, 1141-1152.
-
(1993)
J. Cell Biol
, vol.121
, pp. 1141-1152
-
-
Wayner, E.A.1
Gil, S.G.2
Murphy, G.F.3
Wilke, M.S.4
Carter, W.G.5
-
43
-
-
0035479818
-
Syndecan-4 and focal adhesion function
-
Woods, A., and Couchman, J. R. (2001). Syndecan-4 and focal adhesion function. Curr. Opin. Cell Biol. 13, 578-583.
-
(2001)
Curr. Opin. Cell Biol
, vol.13
, pp. 578-583
-
-
Woods, A.1
Couchman, J.R.2
|