Inhibition of p21-activated kinase 1 by IPA-3 attenuates secondary injury after traumatic brain injury in mice

Brain Research

Volumn 1585, Issue , 2014, Pages 13-22

  Ji, Xinran ^a   Zhang, Wei ^a   Zhang, Lihai ^a   Zhang, Licheng ^a   Zhang, Yiling ^a   Tang, Peifu ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

BBB disruption; Brain edema; IPA 3; Neurological functions; PAK1; Traumatic brain injury

Indexed keywords

1,1' DISULFANEDIYLDINAPHTHALEN 2 OL; CASPASE 3; MESSENGER RNA; NEUROPROTECTIVE AGENT; P21 ACTIVATED KINASE 1; PROTEIN SERINE THREONINE KINASE INHIBITOR; UNCLASSIFIED DRUG; CASP3 PROTEIN, MOUSE; DISULFIDE; IPA-3 COMPOUND; NAPHTHOL DERIVATIVE; P21 ACTIVATED KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD BRAIN BARRIER; BRAIN WATER; CELL COUNT; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; INJURY SEVERITY; MALE; MEMBRANE PERMEABILITY; MOUSE; NEUROLOGICAL COMPLICATION; NEUROPROTECTION; NONHUMAN; POSTTRAUMATIC COMPLICATION; PROTEIN CLEAVAGE; PROTEIN CONTENT; TRAUMATIC BRAIN INJURY; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN EDEMA; BRAIN INJURIES; DRUG EFFECTS; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; MOTOR ACTIVITY; PHOSPHORYLATION;

MUS;

ANIMALS; APOPTOSIS; BLOOD-BRAIN BARRIER; BRAIN EDEMA; BRAIN INJURIES; CASPASE 3; DISULFIDES; MALE; MICE; MICE, INBRED ICR; MOTOR ACTIVITY; NAPHTHOLS; P21-ACTIVATED KINASES; PHOSPHORYLATION;

EID: 84907611867     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2014.08.026     Document Type: Article

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