Exosomes mediate intercellular transfer of pro-fibrogenic connective tissue growth factor (CCN2) between hepatic stellate cells, the principal fibrotic cells in the liver

Surgery (United States)

Volumn 156, Issue 3, 2014, Pages 548-555

  Charrier, Alyssa ^a   Chen, Ruju ^a   Chen, Li ^a   Kemper, Sherri ^a   Hattori, Takako ^b   Takigawa, Masaharu ^b,c   Brigstock, David R ^a,d,e  

^a THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

^b OKAYAMA UNIVERSITY   (Japan)

^c OKAYAMA UNIVERSITY   (Japan)

^d NATIONWIDE CHILDREN S HOSPITAL   (United States)

^e OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,3' (1,4 PHENYLENE)BIS[N [4 (4,5 DIHYDRO 1H IMIDAZOL 2 YL)PHENYL]ACRYLAMIDE]; BIOLOGICAL MARKER; CONNECTIVE TISSUE GROWTH FACTOR; FLUORESCENT DYE; GREEN FLUORESCENT PROTEIN; MESSENGER RNA; ANILINE DERIVATIVE; BENZYLIDENE DERIVATIVE; CTGF PROTEIN, HUMAN; CTGF PROTEIN, MOUSE; HYBRID PROTEIN;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; COCULTURE; CONTROLLED STUDY; EXOSOME; FIBROGENESIS; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIVER FIBROSIS; MEMBRANE VESICLE; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STELLATE CELL; WESTERN BLOTTING; ACTIVE TRANSPORT; ANIMAL; CELL CULTURE; CELL LINE; DRUG EFFECTS; GENETICS; METABOLISM;

ANILINE COMPOUNDS; ANIMALS; BENZYLIDENE COMPOUNDS; BIOLOGICAL TRANSPORT, ACTIVE; CELL LINE; CELLS, CULTURED; COCULTURE TECHNIQUES; CONNECTIVE TISSUE GROWTH FACTOR; EXOSOMES; HEPATIC STELLATE CELLS; HUMANS; MICE; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84907598459     PISSN: 00396060     EISSN: 15327361     Source Type: Journal    
DOI: 10.1016/j.surg.2014.04.014     Document Type: Article

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