Connective tissue growth factor (CCN2) and microRNA-21 are components of a positive feedback loop in pancreatic stellate cells (PSC) during chronic pancreatitis and are exported in PSC-derived exosomes

Journal of Cell Communication and Signaling

Volumn 8, Issue 2, 2014, Pages 147-156

  Charrier, Alyssa ^a,b   Chen, Ruju ^a   Chen, Li ^a   Kemper, Sherri ^a   Hattori, Takako ^c   Takigawa, Masaharu ^c   Brigstock, David R ^a,b  

^a THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c OKAYAMA UNIVERSITY   (Japan)

Author keywords

Alcohol; Connective tissue growth factor; Fibrosis; Microvesicle; miR; Pancreas

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CD9 ANTIGEN; COLLAGEN; COLLAGEN ALPHA1; CONNECTIVE TISSUE GROWTH FACTOR; MESSENGER RNA; MICRORNA; MICRORNA 148A; MICRORNA 199A 3P; MICRORNA 21; MICRORNA 211; MICRORNA 802; UNCLASSIFIED DRUG;

ALCOHOLIC PANCREATITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL ISOLATION; CHRONIC PANCREATITIS; CONTROLLED STUDY; DOWN REGULATION; EXOSOME; EXTRACELLULAR SPACE; IMMUNOREACTIVITY; MALE; MOUSE; NONHUMAN; PANCREATIC STELLATE CELL; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

MURINAE;

EID: 84904022899     PISSN: 18739601     EISSN: 1873961X     Source Type: Journal    
DOI: 10.1007/s12079-014-0220-3     Document Type: Article

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