Targeted H3R26 Deimination Specifically Facilitates Estrogen Receptor Binding by Modifying Nucleosome Structure

PLoS Genetics

Volumn 10, Issue 9, 2014, Pages

  Guertin, Michael J ^a   Zhang, Xuesen ^b,c   Anguish, Lynne ^c   Kim, Sohyoung ^a   Varticovski, Lyuba ^a   Lis, John T ^d   Hager, Gordon L ^a   Coonrod, Scott A ^c  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NANJING MEDICAL UNIVERSITY   (China)

^c Animal Health Diagnostic Center   (United States)

^d Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ESTRADIOL; ESTROGEN RECEPTOR; HISTONE; PEPTIDYLARGININE DEIMINASE 2; PROTEIN ARGININE DEIMINASE; UNCLASSIFIED DRUG; ESTROGEN; HYDROLASE; NUCLEOSOME; PROTEIN BINDING; PROTEIN-ARGININE DEIMINASE;

ARTICLE; BREAST CANCER CELL LINE; CANCER SURVIVAL; CONTROLLED STUDY; CORRELATIONAL STUDY; ESTROGEN RECEPTOR POSITIVE BREAST CANCER; GENOMICS; HISTONE DEIMINATION; HISTONE MODIFICATION; HUMAN; HUMAN CELL; NUCLEOSOME; PROTEIN DNA BINDING; PROTEIN EXPRESSION; RECEPTOR BINDING; BREAST TUMOR; CHROMATIN ASSEMBLY AND DISASSEMBLY; DRUG EFFECTS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; MCF 7 CELL LINE; METABOLISM; MORTALITY; PROGNOSIS;

BREAST NEOPLASMS; CHROMATIN ASSEMBLY AND DISASSEMBLY; ESTROGENS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENOMICS; HISTONES; HUMANS; HYDROLASES; MCF-7 CELLS; NUCLEOSOMES; PROGNOSIS; PROTEIN BINDING; RECEPTORS, ESTROGEN;

EID: 84907588752     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004613     Document Type: Article

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