Different fates of oocytes with DNA double-strand breaks in vitro and in vivo

Cell Cycle

Volumn 13, Issue 17, 2014, Pages 2674-2680

  Lin, Fei ^a   Ma, Xue Shan ^a   Wang, Zhen Bo ^a   Wang, Zhong Wei ^a   Luo, Yi Bo ^a   Huang, Lin ^a   Jiang, Zong Zhe ^a   Hu, Meng Wen ^a   Schatten, Heide ^b   Sun, Qing Yuan ^a  

^a INSTITUTE OF ZOOLOGY   (China)

^b UNIVERSITY OF MISSOURI   (United States)

Author keywords

Apoptosis; DNA double strand breaks; Meiosis; Oocyte; Spindle assembly checkpoint

Indexed keywords

DNA; BLEOMYCIN; PHLEOMYCIN;

ANAPHASE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CYCLE M PHASE; CELL DAMAGE; CELL FATE; CELL MATURATION; CENTROMERE; CHROMOSOME ABERRATION; CONTROLLED STUDY; DOUBLE STRANDED DNA BREAK; FEMALE; GERMINAL VESICLE BREAKDOWN; IN VITRO STUDY; IN VIVO STUDY; M PHASE CELL CYCLE CHECKPOINT; MEIOSIS; METAPHASE; MICROTUBULE; MOUSE; NONHUMAN; OOCYTE; POLAR BODY; TELOPHASE; ANIMAL; APOPTOSIS; CELL CULTURE; CELL LINEAGE; CYTOLOGY; DRUG EFFECTS; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; PROPHASE; TIME;

ANIMALS; APOPTOSIS; BLEOMYCIN; CELL LINEAGE; CELLS, CULTURED; DNA BREAKS, DOUBLE-STRANDED; FEMALE; IN VITRO TECHNIQUES; KINETOCHORES; M PHASE CELL CYCLE CHECKPOINTS; MEIOSIS; MICE, INBRED ICR; MICROTUBULES; OOCYTES; POLAR BODIES; PROPHASE; TIME FACTORS;

EID: 84907581204     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/15384101.2015.945375     Document Type: Article

References (26)

1. De Bont R, van Larebeke N. Endogenous DNA damage in humans: a review of quantitative data. Mutagenesis 2004; 19:169-85; PMID: 15123782; http://dx.doi.org/10.1093/mutage/geh025
2. Kerr JB, Hutt KJ, Michalak EM, Cook M, Vandenberg CJ, Liew SH, Bouillet P, Mills A, Scott CL, Findlay JK, et al. DNA damage-induced primordial follicle oocyte apoptosis and loss of fertility require TAp63-mediated induction of Puma and Noxa. Mol Cell 2012; 48:343-52; PMID: 23000175; http://dx.doi.org/10.1016/j.molcel.2012.08.017
3. Carroll J, Marangos P. The DNA damage response in mammalian oocytes. Front Genet 2013; 4:117; PMID: 23805152; http://dx.doi.org/10.3389/fgene.2013.00117
4. Shiloh Y. ATM and ATR: networking cellular responses to DNA damage. Curr Opin Genet Dev 2001; 11:71-7; PMID: 11163154; http://dx.doi.org/10.1016/S0959-437X(00)00159-3
5. Durocher D, Jackson SP. DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme? Curr Opin Cell Biol 2001; 13:225-31; PMID: 11248557; http://dx.doi.org/10.1016/S0955-0674(00)00201-5
6. Bakkenist CJ, Kastan MB. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 2003; 421:499-506; PMID: 12556884; http://dx.doi.org/10.1038/nature01368
7. Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 1998; 273:5858-68; PMID: 9488723; http://dx.doi.org/10.1074/jbc.273.10.5858
8. Jacquet P. Sensitivity of germ cells and embryos to ionizing radiation. J Biol Regul Homeost Agents 2004; 18:106-14; PMID: 15471212
9. Suh EK, Yang A, Kettenbach A, Bamberger C, Michaelis AH, Zhu Z, Elvin JA, Bronson RT, Crum CP, McKeon F. p63 protects the female germ line during meiotic arrest. Nature 2006; 444:624-8; PMID: 17122775; http://dx.doi.org/10.1038/nature05337
10. Yuen WS, Merriman JA, O'Bryan MK, Jones KT. DNA double strand breaks but not interstrand crosslinks prevent progress through meiosis in fully grown mouse oocytes. PLoS One 2012; 7:e43875; PMID: 22928046; http://dx.doi.org/10.1371/journal.pone.0043875
11. Marangos P, Carroll J. Oocytes progress beyond prophase in the presence of DNA damage. Curr Biol 2012; 22:989-94; PMID: 22578416; http://dx.doi.org/10.1016/j.cub.2012.03.063
12. Mailhes JB, Marchetti F, Phillips GL, Jr., Barnhill DR. Preferential pericentric lesions and aneuploidy induced in mouse oocytes by the topoisomerase II inhibitor etoposide. Teratog Carcinog Mutagen 1994; 14:39-51; PMID: 7910418; http://dx.doi.org/10.1002/tcm.1770140106
13. Li XM, Yu C, Wang ZW, Zhang YL, Liu XM, Zhou D, Sun QY, Fan HY. DNA topoisomerase II is dispensable for oocyte meiotic resumption but is essential for meiotic chromosome condensation and separation in mice. Biol Reprod 2013; 89:118; PMID: 24048577; http://dx.doi.org/10.1095/biolreprod.113.110692
14. Conti M, Hsieh M, Zamah AM, Oh JS. Novel signaling mechanisms in the ovary during oocyte maturation and ovulation. Mol Cell Endocrinol 2012; 356:65-73; PMID: 22101318; http://dx.doi.org/10.1016/j.mce.2011.11.002
15. Stanford JS, Lieberman SL, Wong VL, Ruderman JV. Regulation of the G2/M transition in oocytes of xenopus tropicalis. Dev Biol 2003; 260:438-48; PMID: 12921744; http://dx.doi.org/10.1016/S0012-1606(03)00259-8
16. Cahill D, Connor B, Carney JP. Mechanisms of eukaryotic DNA double strand break repair. Front Biosci 2006; 11:1958-76; PMID: 16368571; http://dx.doi.org/10.2741/1938
17. Sancar A, Lindsey-Boltz LA, Unsal-Kacmaz K, Linn S. Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annu Rev Biochem 2004; 73:39-85; PMID: 15189136; http://dx.doi.org/10.1146/annurev.biochem.73.011303.073723
18. Yukawa M, Oda S, Mitani H, Nagata M, Aoki F. Deficiency in the response to DNA double-strand breaks in mouse early preimplantation embryos. Biochem Biophys Res Commun 2007; 358:578-84; PMID: 17498656; http://dx.doi.org/10.1016/j.bbrc.2007.04.162
19. Wang ZW, Ma XS, Ma JY, Luo YB, Lin F, Wang ZB, Fan HY, Schatten H, Sun QY. Laser microbeam-induced DNA damage inhibits cell division in fertilized eggs and early embryos. Cell Cycle 2013; 12:3336-44; PMID: 24036543; http://dx.doi.org/10.4161/cc.26327
20. Yoo HY, Kumagai A, Shevchenko A, Dunphy WG. Adaptation of a DNA replication checkpoint response depends upon inactivation of Claspin by the Polo-like kinase. Cell 2004; 117:575-88; PMID: 15163406; http://dx.doi.org/10.1016/S0092-8674(04)00417-9
21. Hashimoto H, Sudo T, Mikami Y, Otani M, Takano M, Tsuda H, Itamochi H, Katabuchi H, Ito M, Nishimura R. Germ cell specific protein VASA is over-expressed in epithelial ovarian cancer and disrupts DNA damage-induced G2 checkpoint. Gynecol Oncol 2008; 111:312-9; PMID: 18805576; http://dx.doi.org/10.1016/j.ygyno.2008.08.014
22. Suganuma M, Kawabe T, Hori H, Funabiki T, Okamoto T. Sensitization of cancer cells to DNA damage-induced cell death by specific cell cycle G2 checkpoint abrogation. Cancer Res 1999; 59:5887-91; PMID: 10606229
23. Xiao Z, Xue J, Sowin TJ, Zhang H. Differential roles of checkpoint kinase 1, checkpoint kinase 2, and mitogen-activated protein kinase-activated protein kinase 2 in mediating DNA damage-induced cell cycle arrest: implications for cancer therapy. Mol Cancer Ther 2006; 5:1935-43; PMID: 16928813; http://dx.doi.org/10.1158/1535-7163.MCT-06-0077
24. Ma JY, Ou Yang YC, Wang ZW, Wang ZB, Jiang ZZ, Luo SM, Hou Y, Liu ZH, Schatten H, Sun QY. The effects of DNA double-strand breaks on mouse oocyte meiotic maturation. Cell Cycle 2013; 12:1233-41; PMID: 23518501; http://dx.doi.org/10.4161/cc.24311
25. De Souza CP, Osmani SA. A new level of spindle assembly checkpoint inactivation that functions without mitotic spindles. Cell Cycle 2011; 10:3805-6; PMID: 22067564; http://dx.doi.org/10.4161/cc.10.22.18187
26. Soleimani R, Heytens E, Darzynkiewicz Z, Oktay K. Mechanisms of chemotherapy-induced human ovarian aging: double strand DNA breaks and microvascular compromise. Aging (Albany NY) 2011; 3:782-93; PMID: 21869459