Out-of-Sequence Signal 3 as a Mechanism for Virus-Induced Immune Suppression of CD8 T Cell Responses

PLoS Pathogens

Volumn 10, Issue 9, 2014, Pages

  Urban, Stina L ^a   Welsh, Raymond M ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; GRANZYME B; STAT PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; INTERFERON; MESSENGER RNA; POLYINOSINIC POLYCYTIDYLIC ACID; SOCS1 PROTEIN, MOUSE; SUPPRESSOR OF CYTOKINE SIGNALING;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWNSTREAM PROCESSING; FLOW CYTOMETRY; IMMUNOSUPPRESSIVE TREATMENT; MALE; MOUSE; NONHUMAN; PHOSPHORYLATION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; SPLEEN CELL; VIRUS INFECTION; ANIMAL; C57BL MOUSE; CELL CULTURE; DRUG EFFECTS; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIROLOGY; VIRUS ACTIVATION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; IMMUNOSUPPRESSION; INTERFERON TYPE I; LYMPHOCYTE ACTIVATION; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MALE; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; POLY I-C; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; VIRUS ACTIVATION;

EID: 84907574364     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004357     Document Type: Article

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