Effect of prebiotics on the fecal microbiota of elderly volunteers after dietary supplementation of Bacillus coagulans GBI-30, 6086

Anaerobe

Volumn 30, Issue , 2014, Pages 75-81

  Nyangale, Edna P ^a   Farmer, Sean ^b   Keller, David ^b   Chernoff, David ^b   Gibson, Glenn R ^a  

^a UNIVERSITY OF READING   (United Kingdom)

^b Ganeden Biotech Mayfield Heights ^*  (United States)

Author keywords

Bacillus coagulans; Batch culture fermentation; Fructooligosaccharides; Galactooligosaccharides; Probiotic; Synbiotic

Indexed keywords

ACETIC ACID; BC 30; BUTYRIC ACID; CARBOXYLIC ACID DERIVATIVE; FRUCTOSE OLIGOSACCHARIDE; GALACTOSE OLIGOSACCHARIDE; PLACEBO; PREBIOTIC AGENT; PROBIOTIC AGENT; PROPIONIC ACID; UNCLASSIFIED DRUG; CARBOXYLIC ACID; OLIGOSACCHARIDE;

AGED; ANAEROBIC REACTOR; ARTICLE; BACILLUS; BACILLUS COAGULANS; BACTERIUM CULTURE; CLOSTRIDIUM; CLOSTRIDIUM LITUSEBURENSE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CROSSOVER PROCEDURE; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; DRUG DETERMINATION; EUBACTERIUM; EUBACTERIUM RECTALE; FAECALIBACTERIUM PRAUSNITZII; FECES MICROFLORA; FLUORESCENCE IN SITU HYBRIDIZATION; GAS CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; IN VITRO STUDY; INTESTINE FLORA; NONHUMAN; NORMAL HUMAN; POPULATION DENSITY; VERY ELDERLY; VOLUNTEER; BACTERIAL LOAD; FECES; FEMALE; GROWTH, DEVELOPMENT AND AGING; MALE; MICROBIOLOGY; MICROFLORA; RANDOMIZED CONTROLLED TRIAL; THEORETICAL MODEL;

AGED; AGED, 80 AND OVER; BACILLUS; BACTERIAL LOAD; CARBOXYLIC ACIDS; CHROMATOGRAPHY, GAS; CROSS-OVER STUDIES; DIETARY SUPPLEMENTS; FECES; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; MICROBIOTA; MODELS, THEORETICAL; OLIGOSACCHARIDES; PLACEBOS; PREBIOTICS; PROBIOTICS; VOLUNTEERS;

EID: 84907551646     PISSN: 10759964     EISSN: 10958274     Source Type: Journal    
DOI: 10.1016/j.anaerobe.2014.09.002     Document Type: Article

References (53)

1. Leser T.D., Molbak L. Better living through microbial action: the benefits of the mammalian gastrointestinal microbiota on the host. Environ Microbiol 2009, 11:2194-2206.
2. Ley R.E., Peterson D.A., Gordon J.I. Ecological and evolutionary forces shaping microbial diversity in the human intestine. Cell 2006, 124:837-848.
3. Bäckhed F., Ley R.E., Sonnenburg J.L., Peterson D.A., Gordon J.I. Host-bacterial mutualism in the human intestine. Science 2005, 307:1915-1920.
4. Cox M.A., Jackson J., Stanton M., Rojas-Triana A., Bober L., Laverty M., et al. Short-chain fatty acids act as antinflammatory mediators by regulating prostaglandin E-2 and cytokines. World J Gastroenterol 2009, 15:5549-5557.
5. Lin H.V., Frassetto A., Kowalik E.J., Nawrocki A.R., Lu M.F.M., Kosinski J.R., et al. Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms. Plos One 2012, 7.
6. Hooper L.V., Midtvedt T., Gordon J.I. How host-microbial interactions shape the nutrient environment of the mammalian intestine. Ann Rev Nutr 2002, 22:283-307.
7. Stark P.L., Lee A. The microbial ecology of the large bowel of breast-fed and formula-fed infants during the 1st year of life. JMed Microbiol 1982, 15:189-203.
8. Benno Y., Sawada K., Mitsuoka T. The intestinal microflora of infants - composition of fecal flora in breast-fed and bottle-fed Infants. Microbiol Immunol 1984, 28:975-986.
9. Palmer C., Bik E., Digiulio D., Relman D., Brown P. Development of the human infant intestinal microbiota. PLoS Biol 2007, 5:1556-1573.
10. Duncan S.H., Flint H.J. Probiotics and prebiotics and health in ageing populations. Maturitas 2013, 75:44-50.
11. Biagi E., Candela M., Turroni S., Garagnani P., Franceschi C., Brigidi P. Ageing and gut microbes: perspectives for health maintenance and longevity. Pharmacol Res 2013, 69:11-20.
12. Rea M.C., O'Sullivan O., Shanahan F., O'Toole P.W., Stanton C., Ross R.P., et al. Clostridium difficile carriage in elderly subjects and associated changes in the intestinal microbiota. JClin Microbiol 2012, 50:867-875.
13. Candela M., Guidotti M., Fabbri A., Brigidi P., Franceschi C., Fiorentini C. Human intestinal microbiota: cross-talk with the host and its potential role in colorectal cancer. CRC CR Rev Microbiol 2011, 37:1-14.
14. Aspinall R., Andrew D. Immunosenescence: potential causes and strategies for reversal. Biochem Soc 2000, 28:250-254.
15. Neutra M.R., Mantis N.J., Kraehenbuhl J.P. Collaboration of epithelial cells with organized mucosal lymphoid tissues. Nat Immunol 2001, 2:1004-1009.
16. Biagi E., Candela M., Fairweather-Tait S., Franceschi C., Brigidi P. Ageing of the human metaorganism: the microbial counterpart. Age 2012, 34:247-267.
17. Cheng J., Palva A., de Vos W., Satokari R. Contribution of the intestinal microbiota to human health: from birth to 100 Years of age. Between pathogenicity and commensalism 2013, 323-346. Springer Berlin, Heidelberg. U. Dobrindt, J.H. Hacker, C. Svanborg (Eds.).
18. Mueller S., Saunier K., Hanisch C., Norin E., Alm L., Midtvedt T., et al. Differences in fecal microbiota in different European study populations in relation to age, gender, and country: a cross-sectional study. Appl Environ Microbiol 2006, 72:1027-1033.
19. Eiseman B., Silen W., Bascom G.S., Kauvar A.J. Fecal enema as an adjunct in the treatment of pseudomembranous enterocolitis. Surgery 1958, 44:854-859.
20. Guo B., Harstall C., Louie T., Veldhuyzen van Zanten S., Dieleman L.A. Systematic review: faecal transplantation for the treatment of Clostridium difficile-associated disease. Aliment Pharm Ther 2012, 35:865-875.
21. Kelly C.R., de Leon L., Jasutkar N. Fecal microbiota transplantation for relapsing Clostridium difficile infection in 26 patients methodology and results. JClin Gastroenterol 2012, 46:145-149.
22. Gibson G., Roberfroid M. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. JNutr 1995, 125:1401-1412.
23. Blottiere H.M., Buecher B., Galmiche J.P., Cherbut C. Molecular analysis of the effect of short-chain fatty acids on intestinal cell proliferation. PNutr Soc 2003, 62:101-106.
24. Dong H.L., Rowland I., Yaqoob P. Comparative effects of six probiotic strains on immune function invitro. Br J Nutr 2012, 108:459-470.
25. Ahmed M., Prasad J., Gill H., Stevenson L., Gopal P. Impact of consumption of different levels of Bifidobacterium lactis HN019 on the intestinal microflora of elderly human subjects. JNutr Health Aging 2007, 11:26-31.
26. Lahtinen S.J., Tammela L., Korpela J., Parhiala R., Ahokoski H., Mykkanen H., et al. Probiotics modulate the Bifidobacterium microbiota of elderly nursing home residents. Age 2009, 31:59-66.
27. Moro-Garcia M.A., Alonso-Arias R., Baltadjieva M., Benitez C.F., Barrial M.A.F., Ruisanchez E.D., et al. Oral supplementation with Lactobacillus delbrueckii subsp bulgaricus 8481 enhances systemic immunity in elderly subjects. Age 2013, 35:1311-1326.
28. Tuohy K.M., Kolida S., Lustenberger A.M., Gibson G.R. The prebiotic effects of biscuits containing partially hydrolysed guar gum and fructo-oligosaccharides - a human volunteer study. Br J Nutr 2001, 86:341-348.
29. De Preter V., Falony G., Windey K., Hamer H.M., De Vuyst L., Verbeke K. The prebiotic, oligofructose-enriched inulin modulates the faecal metabolite profile: an invitro analysis. Mol Nutr Food Res 2010, 54:1791-1801.
30. Hyronimus B., Le Marrec C., Hadj Sassi A., Deschamps A. Acid and bile tolerance of spore-forming lactic acid bacteria. Int J Food Microbiol 2000, 61:193-197.
31. Maathuis A.J.H., Keller D., Farmer S. Survival and metabolic activity of the GanedenBC30 strain of Bacillus coagulans in a dynamic invitro model of the stomach and small intestine. Benef Microbes 2010, 1:31-36.
32. Honda H., Gibson G.R., Farmer S., Keller D., McCartney A.L. Use of a continuous culture fermentation system to investigate the effect of GanedenBC30 (Bacillus coagulans GBI-30, 6086) supplementation on pathogen survival in the human gut microbiota. Anaerobe 2011, 17:36-42.
33. Le Marrec C., Hyronimus B., Bressollier P., Verneuil B., Urdaci M.C. Biochemical and genetic characterization of coagulin, a new antilisterial bacteriocin in the pediocin family of bacteriocins, produced by Bacillus coagulans I4. Appl Environ Microb 2000, 66:5213-5220.
34. Bizani D., Brandelli A. Characterization of a bacteriocin produced by a newly isolated Bacillus sp. Strain 8 A. JAppl Microb 2002, 93:512-519.
35. Kalman D., Schwartz H., Alvarez P., Feldman S., Pezzullo J., Krieger D. Aprospective, randomized, double-blind, placebo-controlled parallel-group dual site trial to evaluate the effects of a Bacillus coagulans - based product on functional intestinal gas symptoms. BMC Gastroenterol 2009, 9:85.
36. Jensen G.S., Benson K.F., Carter S.G., Endres J.R. GanedenBC(30)(TM) cell wall and metabolites: anti-inflammatory and immune modulating effects invitro. BMC Immunol 2010, 11.
37. Franks A.H., Harmsen H.J.M., Raangs G.C., Jansen G.J., Schut F., Welling G.W. Variations of bacterial populations in human faeces measured by fluorescent in situ hybridization with group-specific 16S rRNA-targeted oligonucleotide probes. Appl Environ Microbiol 1998, 64:3336-3345.
38. Manz W., Amann R., Ludwig W., Vancanneyt M., Schleifer K.H. Application of a suite of 16S rRNA-specific oligonucleotide probes designed to investigate bacteria of the phylum cytophaga-flavobacter-bacteroides in the natural environment. Microbiol-UK 1996, 142:1097-1106.
39. Suau A., Rochet V., Sghir A., Gramet G., Brewaeys S., Sutren M., et al. Fusobacterium prausnitzii and related species represent a dominant group within the human fecal flora. Syst Appl Microbiol 2001, 24:139-145.
40. Cummings J.H., Macfarlane G.T. Colonic microflora: nutrition and health. Nutrition 1997, 13:476-477.
41. Sekirov I., Tam N.M., Jogova M., Robertson M.L., Li Y., Lupp C., et al. Antibiotic-induced perturbations of the intestinal microbiota alter host susceptibility to enteric infection. Infect Immun 2008, 76:4726-4736.
42. Sabikhi L., Babu R., Thompkinson D.K., Kapila S. Resistance of Microencapsulated Lactobacillus acidophilus LA1 to processing treatments and simulated gut conditions. Food Bioprocess Tech 2010, 3:586-593.
43. Ortakci F., Sert S. Stability of free and encapsulated Lactobacillus acidophilus ATCC 4356 in yogurt and in an artificial human gastric digestion system. JDairy Sci 2012, 95:6918-6925.
44. Borges S., Barbosa J., Camilo R., Carvalheira A., Silva J., Sousa S., et al. Effects of encapsulation on the viability of probiotic strains exposed to lethal conditions. Int J Food Sci Tech 2012, 47:416-421.
45. Vulevic J., Drakoularakou A., Yaqoob P., Tzortzis G., Gibson G.R. Modulation of the fecal microflora profile and immune function by a novel trans-galactooligosaccharide mixture (B-GOS) in healthy elderly volunteers. Am J Clin Nutr 2008, 88:1438-1446.
46. Sokol H., Pigneur B., Watterlot L., Lakhdari O., Bermudez-Humaran L.G., Gratadoux J.J., et al. Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl Acad Sci U S A 2008, 105:16731-16736.
47. McIntyre A., Gibson P.R., Young G.P. Butyrate production from dietary fibre and protection against large bowel cancer in a rat model. Gut 1993, 34:386-391.
48. Scheppach W. Effects of short chain fatty acids on gut morphology and function. Gut 1994, 35:S35-S38.
49. Quigley E. Gut microbiota and the role of probiotics in therapy. Curr Opin Pharmacol 2011, 11:593-603.
50. Louis P., Scott K.P., Duncan S.H., Flint H.J. Understanding the effects of diet on bacterial metabolism in the large intestine. JAppl Microbiol 2007, 102:1197-1208.
51. Manderson K., Pinart M., Tuohy K.M., Grace W.E., Hotchkiss A.T., Widmer W., et al. Invitro determination of prebiotic properties of oligosaccharides derived from an orange juice manufacturing by-product stream. Appl Environ Microbiol 2005, 71:8383-8389.
52. Connolly M.L., Lovegrove J.A., Tuohy K.M. Invitro evaluation of the microbiota modulation abilities of different sized whole oat grain flakes. Anaerobe 2010, 16:483-488.
53. Chen L.X., Li P., Wang J.J., Li X.L., Gao H.J., Yin Y.L., et al. Catabolism of nutritionally essential amino acids in developing porcine enterocytes. Amino Acids 2009, 37:143-152.