HIF-2α regulates NANOG expression in human embryonic stem cells following hypoxia and reoxygenation through the interaction with an oct-sox cis regulatory element

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Petruzzelli, Raffaella ^a   Christensen, David R ^a   Parry, Kate L ^a   Sanchez Elsner, Tilman ^a   Houghton, Franchesca D ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE; HYPOXIA INDUCIBLE FACTOR 2ALPHA; OCTAMER TRANSCRIPTION FACTOR 4; OXYGEN; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; HOMEODOMAIN PROTEIN; NANOG PROTEIN, HUMAN; PROTEIN BINDING; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SOX;

ARTICLE; CELL HYPOXIA; CELL RENEWAL; CIS REGULATORY ELEMENT; CONTROLLED STUDY; DNA STRUCTURE; EMBRYO; EMBRYONIC STEM CELL; EUCHROMATIN; GENETIC TRANSCRIPTION; HETEROCHROMATIN; HISTONE MODIFICATION; HUMAN; HUMAN CELL; HYPOXIC RESPONSE ELEMENT; IN VIVO STUDY; PLURIPOTENT STEM CELL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REOXYGENATION; STEM CELL CULTURE; CELL LINE; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; REGULATORY SEQUENCE; TIME FACTOR;

BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL HYPOXIA; CELL LINE; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION; HISTONES; HOMEODOMAIN PROTEINS; HUMANS; OCTAMER TRANSCRIPTION FACTOR-3; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; REGULATORY SEQUENCES, NUCLEIC ACID; SOXB1 TRANSCRIPTION FACTORS; TIME FACTORS; TRANSCRIPTION FACTORS;

EID: 84907546579     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0108309     Document Type: Article

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